Development and biological evaluation of C60 fulleropyrrolidine-thalidomide dyad as a new anti-inflammation agent

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 18, 2008, Pages 8619-8626

  Huang, Sheng Tung ^a   Ho, Chia Shin ^a   Lin, Chun Mao ^b   Fang, Hsu Wei ^a   Peng, Yi Xiang ^a  

^a NATIONAL TAIPEI UNIVERSITY OF TECHNOLOGY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Anti inflammation; C60 fulleropyrrolidine; Nitric oxide; Thalidomide; TNF

Indexed keywords

FULLERENE DERIVATIVE; FULLEROPYRROLIDINE THALIDOMIDE COMPLEX; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PYRROLIDINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; THALIDOMIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ENZYME PHOSPHORYLATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL SURVIVAL; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FULLERENES; LIPOPOLYSACCHARIDES; MACROPHAGES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; PYRROLIDINES; REACTIVE OXYGEN SPECIES; THALIDOMIDE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 51349169729     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.08.004     Document Type: Article

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