Prognostic impact of marginal adipose tissue invasion in ductal carcinoma of the breast

American Journal of Clinical Pathology

Volumn 130, Issue 3, 2008, Pages 382-388

  Yamaguchi, Junzo ^a   Ohtani, Hiroshi ^b   Nakamura, Kazukuni ^a   Shimokawa, Isao ^b   Kanematsu, Takashi ^b  

^a NATIONAL HOSPITAL ORGANIZATION   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

Adipose tissue invasion; Breast cancer; Lymph node status; Lymphatic vessel invasion; Prognosis

Indexed keywords

ADIPOSE TISSUE; ADULT; AGED; ARTICLE; AXILLARY LYMPH NODE; BREAST CARCINOMA; BREAST DUCT CARCINOMA; CANCER CELL; CANCER INVASION; CANCER SURVIVAL; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE FREE SURVIVAL; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; LYMPH VESSEL; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS; REPRODUCIBILITY; RISK FACTOR; SURVIVAL RATE; SURVIVAL TIME;

ADIPOSE TISSUE; ADULT; AGED; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; FEMALE; HUMANS; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM INVASIVENESS; PROGNOSIS; RETROSPECTIVE STUDIES;

EID: 51349123575     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/MX6KKA1UNJ1YG8VN     Document Type: Article

References (25)

1. Mattila MM, Ruohola JK, Karpanen T, et al. VEGF-C induced lymphangiogenesis is associated with lymph node metastasis in orthotopic MCF-7 tumors. Int J Cancer. 2002;98:946-951.
2. Ohtani O, Shao XJ, Saitoh M, et al. Lymphatics of the rat mammary gland during virgin, pregnant, lactating and postweaning periods. J Steroid Biochem Mol Biol. 1998;103:335-342.
3. Acs G, Dumoff KL, Solin LJ, et al. Extensive retraction artifact correlates with lymphatic invasion and nodal metastasis and predicts poor outcome in early stage breast carcinoma. Am J Surg Pathol. 2007;31:129-140.
4. Agarwal B, Saxena R, Morimiya A, et al. Lymphangiogenesis does not occur in breast cancer. Am J Surg Pathol. 2005;29:1449-1455.
5. Kimijima I, Ohtake T, Sagara H, et al. Scattered fat invasion: an indicator for poor prognosis in premenopausal, and for positive estrogen receptor in postmenopausal breast cancer patients. Oncology. 2000;59:25-30.
6. Padera TP, Kadambi A, di Tomaso E, et al. Lymphatic metastasis in the absence of functional intratumor lymphatics. Science. 2002;296:1883-1886.
7. Firon M, Shaharabany M, Altstock RT, et al. Dominant negative Met reduces tumorigenicity-metastasis and increases tubule formation in mammary cells. Oncogene. 2000;19:2386-2397.
8. Hasebe T, Imoto S, Sasaki S, et al. A proposal for a new histological classification scheme for predicting short-term tumor recurrence and death in patients with invasive ductal carcinoma of the breast. Jpn J Cancer Res. 1998;89:1358-1373.
9. Hasebe T, Mukai K, Tsuda H, et al. New prognostic histological parameter of invasive ductal carcinoma of the breast: clinicopathological significance of fibrotic focus. Pathol Int. 2000;50:263-272.
10. Gajdos C, Tartter PI, Bleiweiss IJ. Lymphatic invasion, tumor size, and age independent predictors of axillary lymph node metastases in women with T1 breast cancers. Ann Surg. 1999;230:692-696.
11. Nathanson SD, Zarbo RJ, Wachna DL, et al. Microvessels that predict axillary lymph node metastases in patients with breast cancer. Arch Surg. 2000;135:586-594.
12. Schoppmann SF, Bayer G, Aumayr K, et al. Prognostic value of lymphangiogenesis and lymphovascular invasion in invasive breast cancer. Ann Surg. 2004;240:306-312.
13. Fitzgibbons PL, Page DL, Weaver D, et al. Prognostic factors in breast cancer: College of American Pathologists consensus statement 1999. Arch Pathol Lab Med. 2000;124:966-978.
14. Goldhirsch A, Glick JH, Gelber RD, et al. Meeting highlights: international expert consensus on the primary therapy of early breast cancer 2005. Ann Oncol. 2005;16:1569-1583.
15. Woo CS, Silberman H, Nakamura SK, et al. Lymph node status combined with lymphovascular invasion creates a more powerful tool for predicting outcome in patients with invasive breast cancer. Am J Surg. 2002;184:337-340.
16. Mascarel I, Bonichon F, Durand M, et al. Obvious peritumoral emboli: an elusive prognostic factor reappraised: multivariate analysis of 1320 node-negative breast cancers. Eur J Cancer. 1998;34:58-65.
17. Robbins P, Pinder S, Klerk N, et al. Histological grading of breast carcinomas: a study of interobserver agreement. Hum Pathol. 1995;26:873-879.
18. Samaratunga H, Fairweather P, Purdie D. Significance of stromal reaction patterns in invasive urothelial carcinoma. Am J Clin Pathol. 2005;123:851-857.
19. Bulun SE, Price TM, Aitken J, et al. A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription. J Clin Endocrinol Metab. 1993;77:1622-1628.
20. O'Neill JS, Elton RA, Miller WR. Aromatase activity in adipose tissue from breast quadrants: a link with tumor site. Br Med J. 1988;296:741-743.
21. Sasano H, Ozaki M. Aromatase expression and its localization in human breast cancer. J Steroid Biochem Mol Biol. 1997;61:293-298.
22. Sasano H, Harada N. Intratumoral aromatase in human breast, endometrial, and ovarian malignancies. Endocr Rev. 1998;19:593-607.
23. Garofalo C, Koda M, Cascio S, et al. Increased expression of leptin and leptin receptor as a marker of breast cancer progression: possible role of obesity-related stimuli. Clin Cancer Res. 2006;12:1447-1453.
24. Alkarain AA, Kahn HJ, Narod SA, et al. Significance of lymph vessel invasion identified by the endothelial lymphatic marker D2-40 in node negative breast cancer. Mod Pathol. 2007;20:183-191.
25. Seidman JD, Schnaper LA, Aisner SC. Relationship of the size of the invasive component of the primary breast carcinoma to axillary lymph node metastasis. Cancer. 1995;75:65-71.