-
1
-
-
2742529418
-
Human proto-oncogene c-kit: A new cell surface receptor tyrosine kinase for an unidentified ligand
-
Yarden, Y., Kuang, W. J., Yang-Feng, T., Coussens, L., Munemitsu, S. Dull, T. J. et al. (1987) Human proto-oncogene c-kit: A new cell surface receptor tyrosine kinase for an unidentified ligand. Embo J, 6, pp. 3341-3351.
-
(1987)
Embo J
, vol.6
, pp. 3341-3351
-
-
Yarden, Y.1
Kuang, W.J.2
Yang-Feng, T.3
Coussens, L.4
Munemitsu, S.5
Dull, T.J.6
-
2
-
-
0023989811
-
Primary structure of c-kit: Relationship with the CSF-1/PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus
-
Qiu, F. H., Ray, P., Brown, K., Barker, P. E., Jhanwar, S. Ruddle, F. H. et al. (1988) Primary structure of c-kit: Relationship with the CSF-1/ PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus. Embo J, 7, pp. 1003-1011.
-
(1988)
Embo J
, vol.7
, pp. 1003-1011
-
-
Qiu, F.H.1
Ray, P.2
Brown, K.3
Barker, P.E.4
Jhanwar, S.5
Ruddle, F.H.6
-
3
-
-
0025001894
-
Stem cell factor is encoded at the Sl locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor
-
Zsebo, K. M., Williams, D. A., Geissler, E. N., Broudy, V. C., Martin, F. H. Atkins, H. L. et al. (1990) Stem cell factor is encoded at the Sl locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor. Cell, 63, pp. 213-224.
-
(1990)
Cell
, vol.63
, pp. 213-224
-
-
Zsebo, K.M.1
Williams, D.A.2
Geissler, E.N.3
Broudy, V.C.4
Martin, F.H.5
Atkins, H.L.6
-
4
-
-
0034608859
-
Crystal structure of human stem cell factor: Implication for stem cell factor receptor dimerization and activation
-
Zhang, Z., Zhang, R., Joachimiak, A., Schlessinger, J. and Kong, X. P. (2000) Crystal structure of human stem cell factor: Implication for stem cell factor receptor dimerization and activation. Proc Natl Acad Sci USA, 97, pp. 7732-7737.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 7732-7737
-
-
Zhang, Z.1
Zhang, R.2
Joachimiak, A.3
Schlessinger, J.4
Kong, X.P.5
-
5
-
-
2942594298
-
Juxtamembrane autoinhibition in receptor tyrosine kinases
-
Hubbard, S. R. (2004) Juxtamembrane autoinhibition in receptor tyrosine kinases. Nat Rev Mol Cell Biol, 5, pp. 464-471.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 464-471
-
-
Hubbard, S.R.1
-
6
-
-
2942542387
-
Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase
-
Mol, C. D., Dougan, D. R., Schneider, T. R., Skene, R. J., Kraus, M. L. Scheibe, D. N. et al. (2004) Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase. J Biol Chem, 279, pp. 31655-31663.
-
(2004)
J Biol Chem
, vol.279
, pp. 31655-31663
-
-
Mol, C.D.1
Dougan, D.R.2
Schneider, T.R.3
Skene, R.J.4
Kraus, M.L.5
Scheibe, D.N.6
-
7
-
-
34250024319
-
Recent advances in the understanding of mastocytosis: The role of KIT mutations
-
Orfao, A., Garcia-Montero, A. C., Sanchez, L. and Escribano, L. (2007) Recent advances in the understanding of mastocytosis: The role of KIT mutations. Br J Haematol, 138, pp. 12-30.
-
(2007)
Br J Haematol
, vol.138
, pp. 12-30
-
-
Orfao, A.1
Garcia-Montero, A.C.2
Sanchez, L.3
Escribano, L.4
-
8
-
-
0028231570
-
c-kit is expressed by primitive human hematopoietic cells that give rise to colony-forming cells in stroma-dependent or cytokine-supplemented culture
-
Simmons, P. J., Aylett, G. W., Niutta, S., To, L. B., Juttner, C. A. and Ashman, L. K. (1994) c-kit is expressed by primitive human hematopoietic cells that give rise to colony-forming cells in stroma-dependent or cytokine-supplemented culture. Exp Hematol, 22, pp. 157-165.
-
(1994)
Exp Hematol
, vol.22
, pp. 157-165
-
-
Simmons, P.J.1
Aylett, G.W.2
Niutta, S.3
To, L.B.4
Juttner, C.A.5
Ashman, L.K.6
-
9
-
-
33646825375
-
Regulation of normal and neoplastic human mast cell development in mastocytosis
-
Metcalfe, D. D. (2005) Regulation of normal and neoplastic human mast cell development in mastocytosis. Trans Am Clin Climatol Assoc, 116, pp. 185-203.
-
(2005)
Trans Am Clin Climatol Assoc
, vol.116
, pp. 185-203
-
-
Metcalfe, D.D.1
-
10
-
-
0028796630
-
W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity
-
Huizinga, J. D., Thuneberg, L., Kluppel, M., Malysz, J., Mikkelsen, H. B. and Bernstein, A. (1995) W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature, 373, pp. 347-349.
-
(1995)
Nature
, vol.373
, pp. 347-349
-
-
Huizinga, J.D.1
Thuneberg, L.2
Kluppel, M.3
Malysz, J.4
Mikkelsen, H.B.5
Bernstein, A.6
-
11
-
-
0028861393
-
Expression of the c-kit proto-oncogene and its ligand stem cell factor (SCF) in normal and malignant human testicular tissue
-
Strohmeyer, T., Reese, D., Press, M., Ackermann, R., Hartmann, M. and Slamon, D. (1995) Expression of the c-kit proto-oncogene and its ligand stem cell factor (SCF) in normal and malignant human testicular tissue. J Urol, 153, pp. 511-515.
-
(1995)
J Urol
, vol.153
, pp. 511-515
-
-
Strohmeyer, T.1
Reese, D.2
Press, M.3
Ackermann, R.4
Hartmann, M.5
Slamon, D.6
-
12
-
-
0025765399
-
Preferential expression of c-kit protooncogene transcripts in small cell lung cancer
-
Sekido, Y., Obata, Y., Ueda, R., Hida, T., Suyama, M. Shimokata, K. et al. (1991) Preferential expression of c-kit protooncogene transcripts in small cell lung cancer. Cancer Res, 51, pp. 2416-2419.
-
(1991)
Cancer Res
, vol.51
, pp. 2416-2419
-
-
Sekido, Y.1
Obata, Y.2
Ueda, R.3
Hida, T.4
Suyama, M.5
Shimokata, K.6
-
13
-
-
0032528497
-
The reliability and specificity of c-kit for the diagnosis of acute myeloid leukemias and undifferentiated leukemias. The European Group for the Immunological Classification of Leukemias (EGIL)
-
Bene, M. C., Bernier, M., Casasnovas, R. O., Castoldi, G., Knapp, W. Lanza, F. et al. (1998) The reliability and specificity of c-kit for the diagnosis of acute myeloid leukemias and undifferentiated leukemias. The European Group for the Immunological Classification of Leukemias (EGIL). Blood, 92, pp. 596-599.
-
(1998)
Blood
, vol.92
, pp. 596-599
-
-
Bene, M.C.1
Bernier, M.2
Casasnovas, R.O.3
Castoldi, G.4
Knapp, W.5
Lanza, F.6
-
14
-
-
15644363454
-
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
-
Hirota, S., Isozaki, K., Moriyama, Y., Hashimoto, K., Nishida, T. Ishiguro, S. et al. (1998) Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science, 279, pp. 577-580.
-
(1998)
Science
, vol.279
, pp. 577-580
-
-
Hirota, S.1
Isozaki, K.2
Moriyama, Y.3
Hashimoto, K.4
Nishida, T.5
Ishiguro, S.6
-
15
-
-
0036141147
-
The complexity of KIT gene mutations and chromosome rearrangements and their clinical correlation in gastrointestinal stromal (pacemaker cell) tumors
-
Andersson, J., Sjogren, H., Meis-Kindblom, J. M., Stenman, G., Aman, P. and Kindblom, L. G. (2002) The complexity of KIT gene mutations and chromosome rearrangements and their clinical correlation in gastrointestinal stromal (pacemaker cell) tumors. Am J Pathol, 160, pp. 15-22.
-
(2002)
Am J Pathol
, vol.160
, pp. 15-22
-
-
Andersson, J.1
Sjogren, H.2
Meis-Kindblom, J.M.3
Stenman, G.4
Aman, P.5
Kindblom, L.G.6
-
16
-
-
1842465615
-
Clinicopathologic, phenotypic, and genotypic characteristics of gastrointestinal mesenchymal tumors
-
Emile, J. F., Theou, N., Tabone, S., Cortez, A., Terrier, P. Chaumette, M. T. et al. (2004) Clinicopathologic, phenotypic, and genotypic characteristics of gastrointestinal mesenchymal tumors. Clin Gastroenterol Hepatol, 2, pp. 597-605.
-
(2004)
Clin Gastroenterol Hepatol
, vol.2
, pp. 597-605
-
-
Emile, J.F.1
Theou, N.2
Tabone, S.3
Cortez, A.4
Terrier, P.5
Chaumette, M.T.6
-
17
-
-
1542784354
-
KIT mutations are common in testicular seminomas
-
Kemmer, K., Corless, C. L., Fletcher, J. A., McGreevey, L., Haley, A. Griffith, D. et al. (2004) KIT mutations are common in testicular seminomas. Am J Pathol, 164, pp. 305-313.
-
(2004)
Am J Pathol
, vol.164
, pp. 305-313
-
-
Kemmer, K.1
Corless, C.L.2
Fletcher, J.A.3
McGreevey, L.4
Haley, A.5
Griffith, D.6
-
18
-
-
1542514868
-
Immunophenotyping of acute leukemias and myelodysplastic syndromes
-
Orfao, A., Ortuno, F., de Santiago, M., Lopez, A. and San Miguel, J (2004) Immunophenotyping of acute leukemias and myelodysplastic syndromes. Cytometry A, 58, pp. 62-71.
-
(2004)
Cytometry A
, vol.58
, pp. 62-71
-
-
Orfao, A.1
Ortuno, F.2
de Santiago, M.3
Lopez, A.4
San Miguel, J.5
-
19
-
-
33747113568
-
Mutational analysis of the KIT gene in myelodysplastic syndrome (MDS) and MDS-derived leukemia
-
Lorenzo, F., Nishii, K., Monma, F., Kuwagata, S., Usui, E. and Shiku, H. (2006) Mutational analysis of the KIT gene in myelodysplastic syndrome (MDS) and MDS-derived leukemia. Leuk Res, 30, pp. 1235-1239.
-
(2006)
Leuk Res
, vol.30
, pp. 1235-1239
-
-
Lorenzo, F.1
Nishii, K.2
Monma, F.3
Kuwagata, S.4
Usui, E.5
Shiku, H.6
-
20
-
-
34347236177
-
A comparative study of molecular mutations in 381 patients with myelodysplastic syndrome and in 4130 patients with acute myeloid leukemia
-
Bacher, U., Haferlach, T., Kern, W., Haferlach, C. and Schnittger, S. (2007) A comparative study of molecular mutations in 381 patients with myelodysplastic syndrome and in 4130 patients with acute myeloid leukemia. Haematologica, 92, pp. 744-752.
-
(2007)
Haematologica
, vol.92
, pp. 744-752
-
-
Bacher, U.1
Haferlach, T.2
Kern, W.3
Haferlach, C.4
Schnittger, S.5
-
21
-
-
0028849992
-
c-kit point mutation of extracellular domain in patients with myeloproliferative disorders
-
Nakata, Y., Kimura, A., Katoh, O., Kawaishi, K., Hyodo, H. Abe, K. et al. (1995) c-kit point mutation of extracellular domain in patients with myeloproliferative disorders. Br J Haematol, 91, pp. 661-663.
-
(1995)
Br J Haematol
, vol.91
, pp. 661-663
-
-
Nakata, Y.1
Kimura, A.2
Katoh, O.3
Kawaishi, K.4
Hyodo, H.5
Abe, K.6
-
22
-
-
0036207241
-
Kit and c-kit mutations in mastocytosis: A short overview with special reference to novel molecular and diagnostic concepts
-
Feger, F., Ribadeau, A Dumas, Leriche, L., Valent, P. and Arock, M. (2002) Kit and c-kit mutations in mastocytosis: A short overview with special reference to novel molecular and diagnostic concepts. Int Arch Allergy Immunol, 127, pp. 110-114.
-
(2002)
Int Arch Allergy Immunol
, vol.127
, pp. 110-114
-
-
Feger, F.1
Ribadeau, A.2
Dumas Leriche, L.3
Valent, P.4
Arock, M.5
-
23
-
-
21344465615
-
Clonality and molecular pathogenesis of mastocytosis
-
Akin, C. (2005) Clonality and molecular pathogenesis of mastocytosis. Acta Haematol, 114, pp. 61-69.
-
(2005)
Acta Haematol
, vol.114
, pp. 61-69
-
-
Akin, C.1
-
24
-
-
34250796815
-
Mastocytosis: State of the art
-
Horny, H. P., Sotlar, K. and Valent, P. (2007) Mastocytosis: State of the art. Pathobiology, 74, pp. 121-132.
-
(2007)
Pathobiology
, vol.74
, pp. 121-132
-
-
Horny, H.P.1
Sotlar, K.2
Valent, P.3
-
25
-
-
27244452986
-
Genetics of myeloid malignancies: Pathogenetic and clinical implications
-
Frohling, S., Scholl, C., Gilliland, D. G. and Levine, R. L. (2005) Genetics of myeloid malignancies: Pathogenetic and clinical implications. J Clin Oncol, 23, pp. 6285-6295.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6285-6295
-
-
Frohling, S.1
Scholl, C.2
Gilliland, D.G.3
Levine, R.L.4
-
26
-
-
0027359443
-
Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product
-
Furitsu, T., Tsujimura, T., Tono, T., Ikeda, H., Kitayama, H. Koshimizu, U. et al. (1993) Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product. J Clin Invest, 92, pp. 1736-1744.
-
(1993)
J Clin Invest
, vol.92
, pp. 1736-1744
-
-
Furitsu, T.1
Tsujimura, T.2
Tono, T.3
Ikeda, H.4
Kitayama, H.5
Koshimizu, U.6
-
27
-
-
0028258512
-
Activating mutations of the c-kit proto-oncogene in a human mast cell leukemia cell line
-
Kanakura, Y., Furitsu, T., Tsujimura, T., Butterfield, J. H., Ashman, L. K. Ikeda, H. et al. (1994) Activating mutations of the c-kit proto-oncogene in a human mast cell leukemia cell line. Leukemia, 8, pp. S18-S22.
-
(1994)
Leukemia
, vol.8
-
-
Kanakura, Y.1
Furitsu, T.2
Tsujimura, T.3
Butterfield, J.H.4
Ashman, L.K.5
Ikeda, H.6
-
28
-
-
0038170400
-
Incidence and prognosis of c-KIT and FLT3 mutations in core binding factor (CBF) acute myeloid leukaemias
-
Care, R. S., Valk, P. J., Goodeve, A. C., Abu-Duhier, F. M., Geertsma-Kleinekoort, W. M. Wilson, G. A. et al. (2003) Incidence and prognosis of c-KIT and FLT3 mutations in core binding factor (CBF) acute myeloid leukaemias. Br J Haematol, 121, pp. 775-777.
-
(2003)
Br J Haematol
, vol.121
, pp. 775-777
-
-
Care, R.S.1
Valk, P.J.2
Goodeve, A.C.3
Abu-Duhier, F.M.4
Geertsma-Kleinekoort, W.M.5
Wilson, G.A.6
-
29
-
-
0041737454
-
Activating mutations of RTK/ras signal transduction pathway in pediatric acute myeloid leukemia
-
Meshinchi, S., Stirewalt, D. L., Alonzo, T. A., Zhang, Q., Sweetser, D. A. Woods, W. G. et al. (2003) Activating mutations of RTK/ras signal transduction pathway in pediatric acute myeloid leukemia. Blood, 102, pp. 1474-1479.
-
(2003)
Blood
, vol.102
, pp. 1474-1479
-
-
Meshinchi, S.1
Stirewalt, D.L.2
Alonzo, T.A.3
Zhang, Q.4
Sweetser, D.A.5
Woods, W.G.6
-
30
-
-
3943068350
-
KIT activating mutations: Incidence in adult and pediatric acute myeloid leukemia, and identification of an internal tandem duplication
-
Beghini, A., Ripamonti, C. B., Cairoli, R., Cazzaniga, G., Colapietro, P. Elice, F. et al. (2004) KIT activating mutations: Incidence in adult and pediatric acute myeloid leukemia, and identification of an internal tandem duplication. Haematologica, 89, pp. 920-925.
-
(2004)
Haematologica
, vol.89
, pp. 920-925
-
-
Beghini, A.1
Ripamonti, C.B.2
Cairoli, R.3
Cazzaniga, G.4
Colapietro, P.5
Elice, F.6
-
31
-
-
23744498520
-
Mutations in the receptor tyrosine kinase pathway are associated with clinical outcome in patients with acute myeloblastic leukemia harboring t(8;21)(q22;q22)
-
Nanri, T., Matsuno, N., Kawakita, T., Suzushima, H., Kawano, F. Mitsuya, H. et al. (2005) Mutations in the receptor tyrosine kinase pathway are associated with clinical outcome in patients with acute myeloblastic leukemia harboring t(8;21)(q22;q22). Leukemia, 19, pp. 1361-1366.
-
(2005)
Leukemia
, vol.19
, pp. 1361-1366
-
-
Nanri, T.1
Matsuno, N.2
Kawakita, T.3
Suzushima, H.4
Kawano, F.5
Mitsuya, H.6
-
32
-
-
19944431253
-
AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: Implication in stepwise leukemogenesis and response to Gleevec
-
Wang, Y. Y., Zhou, G. B., Yin, T., Chen, B., Shi, J. Y. Liang, W. X. et al. (2005) AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: Implication in stepwise leukemogenesis and response to Gleevec. Proc Natl Acad Sci USA, 102, pp. 1104-1109.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1104-1109
-
-
Wang, Y.Y.1
Zhou, G.B.2
Yin, T.3
Chen, B.4
Shi, J.Y.5
Liang, W.X.6
-
33
-
-
33646432204
-
Prognostic impact of c-KIT mutations in core binding factor leukemias: An Italian retrospective study
-
Cairoli, R., Beghini, A., Grillo, G., Nadali, G., Elice, F. Ripamonti, C. B. et al. (2006) Prognostic impact of c-KIT mutations in core binding factor leukemias: An Italian retrospective study. Blood, 107, pp. 3463-3468.
-
(2006)
Blood
, vol.107
, pp. 3463-3468
-
-
Cairoli, R.1
Beghini, A.2
Grillo, G.3
Nadali, G.4
Elice, F.5
Ripamonti, C.B.6
-
34
-
-
33344465478
-
KIT-D816 mutations in AML1-ETO-positive AML are associated with impaired event-free and overall survival
-
Schnittger, S., Kohl, T. M., Haferlach, T., Kern, W., Hiddemann, W. Spiekermann, K. et al. (2006) KIT-D816 mutations in AML1-ETO-positive AML are associated with impaired event-free and overall survival. Blood, 107, pp. 1791-1799.
-
(2006)
Blood
, vol.107
, pp. 1791-1799
-
-
Schnittger, S.1
Kohl, T.M.2
Haferlach, T.3
Kern, W.4
Hiddemann, W.5
Spiekermann, K.6
-
35
-
-
0032989226
-
c-kit proto-oncogene exon 8 in-frame deletion plus insertion mutations in acute myeloid leukaemia
-
Gari, M., Goodeve, A., Wilson, G., Winship, P., Langabeer, S. Linch, D. et al. (1999) c-kit proto-oncogene exon 8 in-frame deletion plus insertion mutations in acute myeloid leukaemia. Br J Haematol, 105, pp. 894-900.
-
(1999)
Br J Haematol
, vol.105
, pp. 894-900
-
-
Gari, M.1
Goodeve, A.2
Wilson, G.3
Winship, P.4
Langabeer, S.5
Linch, D.6
-
36
-
-
33744487375
-
Incidence and prognostic impact of c-Kit, FLT3, and Ras gene mutations in core binding factor acute myeloid leukemia (CBF-AML)
-
Boissel, N., Leroy, H., Brethon, B., Philippe, N., de Botton, S. Auvrignon, A. et al. (2006) Incidence and prognostic impact of c-Kit, FLT3, and Ras gene mutations in core binding factor acute myeloid leukemia (CBF-AML). Leukemia, 20, pp. 965-970.
-
(2006)
Leukemia
, vol.20
, pp. 965-970
-
-
Boissel, N.1
Leroy, H.2
Brethon, B.3
Philippe, N.4
de Botton, S.5
Auvrignon, A.6
-
37
-
-
33748467435
-
Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): A Cancer and Leukemia Group B Study
-
Paschka, P., Marcucci, G., Ruppert, A. S., Mrozek, K., Chen, H. Kittles, R. A. et al. (2006) Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): A Cancer and Leukemia Group B Study. J Clin Oncol, 24, pp. 3904-3911.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3904-3911
-
-
Paschka, P.1
Marcucci, G.2
Ruppert, A.S.3
Mrozek, K.4
Chen, H.5
Kittles, R.A.6
-
38
-
-
0034650957
-
C-kit mutations in core binding factor leukemias
-
Beghini, A., Peterlongo, P., Ripamonti, C. B., Larizza, L., Cairoli, R. Morra, E. et al. (2000) C-kit mutations in core binding factor leukemias. Blood, 95, pp. 726-727.
-
(2000)
Blood
, vol.95
, pp. 726-727
-
-
Beghini, A.1
Peterlongo, P.2
Ripamonti, C.B.3
Larizza, L.4
Cairoli, R.5
Morra, E.6
-
39
-
-
51349094696
-
Mutations in KIT and RAS are frequent events in pediatric core-binding factor acute myeloid leukemia
-
Goemans, B. F., Zwaan, C. M., Miller, M., Zimmermann, M., Harlow, A. Meshinchi, S. et al. (2008) Mutations in KIT and RAS are frequent events in pediatric core-binding factor acute myeloid leukemia. Leukemia, 22, pp. 303-307.
-
(2008)
Leukemia
, vol.22
, pp. 303-307
-
-
Goemans, B.F.1
Zwaan, C.M.2
Miller, M.3
Zimmermann, M.4
Harlow, A.5
Meshinchi, S.6
-
40
-
-
85044559428
-
Cooperating mutations of receptor tyrosine kinases and Ras genes in childhood core-binding factor acute myeloid leukemia and a comparative analysis on paired diagnosis and relapse samples
-
Shih, L. Y., Liang, D. C., Huang, C. F., Chang, Y. T., Lai, C. L. Lin, T. H. et al. Cooperating mutations of receptor tyrosine kinases and Ras genes in childhood core-binding factor acute myeloid leukemia and a comparative analysis on paired diagnosis and relapse samples. Leukemia
-
Leukemia
-
-
Shih, L.Y.1
Liang, D.C.2
Huang, C.F.3
Chang, Y.T.4
Lai, C.L.5
Lin, T.H.6
-
41
-
-
33344471932
-
KIT mutations, and not FLT3 internal tandem duplication, are strongly associated with a poor prognosis in pediatric acute myeloid leukemia with t(8;21): A study of the Japanese Childhood AML Cooperative Study Group
-
Shimada, A., Taki, T., Tabuchi, K., Tawa, A., Horibe, K. Tsuchida, M. et al. (2006) KIT mutations, and not FLT3 internal tandem duplication, are strongly associated with a poor prognosis in pediatric acute myeloid leukemia with t(8;21): A study of the Japanese Childhood AML Cooperative Study Group. Blood, 107, pp. 1806-1809.
-
(2006)
Blood
, vol.107
, pp. 1806-1809
-
-
Shimada, A.1
Taki, T.2
Tabuchi, K.3
Tawa, A.4
Horibe, K.5
Tsuchida, M.6
-
42
-
-
33750609891
-
Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin
-
Corbacioglu, S., Kilic, M., Westhoff, M. A., Reinhardt, D., Fulda, S. and Debatin, K. M. (2006) Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin. Blood, 108, pp. 3504-3513.
-
(2006)
Blood
, vol.108
, pp. 3504-3513
-
-
Corbacioglu, S.1
Kilic, M.2
Westhoff, M.A.3
Reinhardt, D.4
Fulda, S.5
Debatin, K.M.6
-
43
-
-
0028856070
-
Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder
-
Nagata, H., Worobec, A. S., Oh, C. K., Chowdhury, B. A., Tannenbaum, S. Suzuki, Y. et al. (1995) Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder. Proc Natl Acad Sci USA, 92, pp. 10560-10564.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 10560-10564
-
-
Nagata, H.1
Worobec, A.S.2
Oh, C.K.3
Chowdhury, B.A.4
Tannenbaum, S.5
Suzuki, Y.6
-
44
-
-
0009013631
-
Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis: Establishment of clonality in a human mast cell neoplasm
-
Longley, B. J., Tyrrell, L., Lu, S. Z., Ma, Y. S., Langley, K. Ding, T. G. et al. (1996) Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis: Establishment of clonality in a human mast cell neoplasm. Nat Genet, 12, pp. 312-314.
-
(1996)
Nat Genet
, vol.12
, pp. 312-314
-
-
Longley, B.J.1
Tyrrell, L.2
Lu, S.Z.3
Ma, Y.S.4
Langley, K.5
Ding, T.G.6
-
45
-
-
13044305857
-
Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis
-
Longley, Jr BJ, Metcalfe, D. D., Tharp, M., Wang, X., Tyrrell, L. Lu, S. Z. et al. (1999) Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis. Proc Natl Acad Sci USA, 96, pp. 1609-1614.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 1609-1614
-
-
Longley Jr., B.J.1
Metcalfe, D.D.2
Tharp, M.3
Wang, X.4
Tyrrell, L.5
Lu, S.Z.6
-
46
-
-
33749368009
-
KIT mutation in mast cells and other bone marrow hematopoietic cell lineages in systemic mast cell disorders: A prospective study of the Spanish Network on Mastocytosis (REMA) in a series of 113 patients
-
Garcia-Montero, A. C., Jara-Acevedo, M., Teodosio, C., Sanchez, M. L., Nunez, R. Prados, A. et al. (2006) KIT mutation in mast cells and other bone marrow hematopoietic cell lineages in systemic mast cell disorders: a prospective study of the Spanish Network on Mastocytosis (REMA) in a series of 113 patients. Blood, 108, pp. 2366-2372.
-
(2006)
Blood
, vol.108
, pp. 2366-2372
-
-
Garcia-Montero, A.C.1
Jara-Acevedo, M.2
Teodosio, C.3
Sanchez, M.L.4
Nunez, R.5
Prados, A.6
-
47
-
-
0032456567
-
Identification of activating c-kit mutations in adult-, but not in childhood-onset indolent mastocytosis: A possible explanation for divergent clinical behavior
-
Buttner, C., Henz, B. M., Welker, P., Sepp, N. T. and Grabbe, J. (1998) Identification of activating c-kit mutations in adult-, but not in childhood-onset indolent mastocytosis: A possible explanation for divergent clinical behavior. J Invest Dermatol, 111, pp. 1227-1231.
-
(1998)
J Invest Dermatol
, vol.111
, pp. 1227-1231
-
-
Buttner, C.1
Henz, B.M.2
Welker, P.3
Sepp, N.T.4
Grabbe, J.5
-
48
-
-
0344643427
-
One-step detection of c-kit point mutations using peptide nucleic acid-mediated polymerase chain reaction clamping and hybridization probes
-
Sotlar, K., Escribano, L., Landt, O., Mohrle, S., Herrero, S. Torrelo, A. et al. (2003) One-step detection of c-kit point mutations using peptide nucleic acid-mediated polymerase chain reaction clamping and hybridization probes. Am J Pathol, 162, pp. 737-746.
-
(2003)
Am J Pathol
, vol.162
, pp. 737-746
-
-
Sotlar, K.1
Escribano, L.2
Landt, O.3
Mohrle, S.4
Herrero, S.5
Torrelo, A.6
-
49
-
-
0031039992
-
A new c-kit mutation in a case of aggressive mast cell disease
-
Pignon, J. M., Giraudier, S., Duquesnoy, P., Jouault, H., Imbert, M. Vainchenker, W. et al. (1997) A new c-kit mutation in a case of aggressive mast cell disease. Br J Haematol, 96, pp. 374-376.
-
(1997)
Br J Haematol
, vol.96
, pp. 374-376
-
-
Pignon, J.M.1
Giraudier, S.2
Duquesnoy, P.3
Jouault, H.4
Imbert, M.5
Vainchenker, W.6
-
50
-
-
0037405219
-
Systemic mastocytosis with associated clonal hematological non-mast-cell lineage disease: Analysis of clinicopathologic features and activating c-kit mutations
-
Pullarkat, V. A., Bueso-Ramos, C., Lai, R., Kroft, S., Wilson, C. S. Pullarkat, S. T. et al. (2003) Systemic mastocytosis with associated clonal hematological non-mast-cell lineage disease: Analysis of clinicopathologic features and activating c-kit mutations. Am J Hematol, 73, pp. 12-17.
-
(2003)
Am J Hematol
, vol.73
, pp. 12-17
-
-
Pullarkat, V.A.1
Bueso-Ramos, C.2
Lai, R.3
Kroft, S.4
Wilson, C.S.5
Pullarkat, S.T.6
-
51
-
-
2642581620
-
Systemic mastocytosis with associated clonal haematological non-mast cell lineage diseases: A histopathological challenge
-
Horny, H. P., Sotlar, K., Sperr, W. R. and Valent, P. (2004) Systemic mastocytosis with associated clonal haematological non-mast cell lineage diseases: A histopathological challenge. J Clin Pathol, 57, pp. 604-608.
-
(2004)
J Clin Pathol
, vol.57
, pp. 604-608
-
-
Horny, H.P.1
Sotlar, K.2
Sperr, W.R.3
Valent, P.4
-
52
-
-
35448970526
-
The origin of neoplastic mast cells in systemic mastocytosis with AML1/ ETO-positive acute myeloid leukemia
-
Nagai, S., Ichikawa, M., Takahashi, T., Sato, H., Yokota, H. Oshima, K. et al. (2007) The origin of neoplastic mast cells in systemic mastocytosis with AML1/ETO-positive acute myeloid leukemia. Exp Hematol, 35, pp. 1747-1752.
-
(2007)
Exp Hematol
, vol.35
, pp. 1747-1752
-
-
Nagai, S.1
Ichikawa, M.2
Takahashi, T.3
Sato, H.4
Yokota, H.5
Oshima, K.6
-
53
-
-
33845193026
-
Neoplastic mast cells in systemic mastocytosis associated with t(8;21) acute myeloid leukemia are derived from the leukemic clone
-
Pullarkat, V., Bedell, V., Kim, Y., Bhatia, R., Nakamura, R. Forman, S. et al. (2007) Neoplastic mast cells in systemic mastocytosis associated with t(8;21) acute myeloid leukemia are derived from the leukemic clone. Leuk Res, 31, pp. 261-265.
-
(2007)
Leuk Res
, vol.31
, pp. 261-265
-
-
Pullarkat, V.1
Bedell, V.2
Kim, Y.3
Bhatia, R.4
Nakamura, R.5
Forman, S.6
-
54
-
-
0023950976
-
Establishment of an immature mast cell line from a patient with mast cell leukemia
-
Butterfield, J. H., Weiler, D., Dewald, G. and Gleich, G. J. (1988) Establishment of an immature mast cell line from a patient with mast cell leukemia. Leuk Res, 12, pp. 345-355.
-
(1988)
Leuk Res
, vol.12
, pp. 345-355
-
-
Butterfield, J.H.1
Weiler, D.2
Dewald, G.3
Gleich, G.J.4
-
55
-
-
0043169405
-
Effects of tyrosine kinase inhibitor STI571 on human mast cells bearing wild-type or mutated c-kit
-
Akin, C BK, D'Ambrosio, C., Kirshenbaum, A. S., Ma, Y., Longley, B. J. and Metcalfe, D. D. (2003) Effects of tyrosine kinase inhibitor STI571 on human mast cells bearing wild-type or mutated c-kit. Exp Hematol, 31, pp. 686-692.
-
(2003)
Exp Hematol
, vol.31
, pp. 686-692
-
-
Akin, C.B.K.1
D'Ambrosio, C.2
Kirshenbaum, A.S.3
Ma, Y.4
Longley, B.J.5
Metcalfe, D.D.6
-
56
-
-
8644277148
-
Aleukemic mast cell leukemia with abnormal immunophenotype and c-kit mutation D816V
-
Noack, F., Sotlar, K., Notter, M., Thiel, E., Valent, P. and Horny, H. P. (2004) Aleukemic mast cell leukemia with abnormal immunophenotype and c-kit mutation D816V. Leuk Lymphoma, 45, pp. 2295-2302.
-
(2004)
Leuk Lymphoma
, vol.45
, pp. 2295-2302
-
-
Noack, F.1
Sotlar, K.2
Notter, M.3
Thiel, E.4
Valent, P.5
Horny, H.P.6
-
57
-
-
0033532190
-
Inhibition of spontaneous receptor phosphorylation by residues in a putative alpha-helix in the KIT intracellular juxtamembrane region
-
Ma, Y., Cunningham, M. E., Wang, X., Ghosh, I., Regan, L. and Longley, B. J. (1999) Inhibition of spontaneous receptor phosphorylation by residues in a putative alpha-helix in the KIT intracellular juxtamembrane region. J Biol Chem, 274, pp. 13399-13402.
-
(1999)
J Biol Chem
, vol.274
, pp. 13399-13402
-
-
Ma, Y.1
Cunningham, M.E.2
Wang, X.3
Ghosh, I.4
Regan, L.5
Longley, B.J.6
-
58
-
-
0029045934
-
Regulation of development, survival and neoplastic growth of mast cells through the c-kit receptor
-
Kitamura, Y., Tsujimura, T., Jippo, T., Kasugai, T. and Kanakura, Y. (1995) Regulation of development, survival and neoplastic growth of mast cells through the c-kit receptor. Int Arch Allergy Immunol, 107, pp. 54-56.
-
(1995)
Int Arch Allergy Immunol
, vol.107
, pp. 54-56
-
-
Kitamura, Y.1
Tsujimura, T.2
Jippo, T.3
Kasugai, T.4
Kanakura, Y.5
-
59
-
-
0035902180
-
Oncogenic kinase signalling
-
Blume-Jensen, P. and Hunter, T. (2001) Oncogenic kinase signalling. Nature, 411, pp. 355-365.
-
(2001)
Nature
, vol.411
, pp. 355-365
-
-
Blume-Jensen, P.1
Hunter, T.2
-
60
-
-
0024991898
-
pEF-BOS, a powerful mammalian expression vector
-
Mizushima, S. and Nagata, S. (1990) pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res, 18, p. 5322.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 5322
-
-
Mizushima, S.1
Nagata, S.2
-
61
-
-
0028890689
-
The fourth immunoglobulin domain of the stem cell factor receptor couples ligand binding to signal transduction
-
Blechman, J. M., Lev, S., Barg, J., Eisenstein, M., Vaks, B. Vogel, Z. et al. (1995) The fourth immunoglobulin domain of the stem cell factor receptor couples ligand binding to signal transduction. Cell, 80, pp. 103-113.
-
(1995)
Cell
, vol.80
, pp. 103-113
-
-
Blechman, J.M.1
Lev, S.2
Barg, J.3
Eisenstein, M.4
Vaks, B.5
Vogel, Z.6
-
62
-
-
0025812785
-
Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase
-
Reith, A. D., Ellis, C., Lyman, S. D., Anderson, D. M., Williams, D. E. Bernstein, A. et al. (1991) Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase. Embo J, 10, pp. 2451-2459.
-
(1991)
Embo J
, vol.10
, pp. 2451-2459
-
-
Reith, A.D.1
Ellis, C.2
Lyman, S.D.3
Anderson, D.M.4
Williams, D.E.5
Bernstein, A.6
-
63
-
-
0027235872
-
Expression of isoforms of the human receptor tyrosine kinase c-kit in leukemic cell lines and acute myeloid leukemia
-
Crosier, P. S., Ricciardi, S. T., Hall, L. R., Vitas, M. R., Clark, S. C. and Crosier, K. E. (1993) Expression of isoforms of the human receptor tyrosine kinase c-kit in leukemic cell lines and acute myeloid leukemia. Blood, 82, pp. 1151-1158.
-
(1993)
Blood
, vol.82
, pp. 1151-1158
-
-
Crosier, P.S.1
Ricciardi, S.T.2
Hall, L.R.3
Vitas, M.R.4
Clark, S.C.5
Crosier, K.E.6
-
64
-
-
0026096497
-
Exon skipping by mutation of an authentic splice site of c-kit gene in W/ W mouse
-
Hayashi, S., Kunisada, T., Ogawa, M., Yamaguchi, K. and Nishikawa, S. (1991) Exon skipping by mutation of an authentic splice site of c-kit gene in W/W mouse. Nucleic Acids Res, 19, pp. 1267-1271.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 1267-1271
-
-
Hayashi, S.1
Kunisada, T.2
Ogawa, M.3
Yamaguchi, K.4
Nishikawa, S.5
-
65
-
-
34548136982
-
Multiple novel alterations in Kit tyrosine kinase in patients with gastrointestinally pronounced systemic mast cell activation disorder
-
Molderings, G. J., Kolck, U. W., Scheurlen, C., Bruss, M., Homann, J. and Von, Kugelgen I. (2007) Multiple novel alterations in Kit tyrosine kinase in patients with gastrointestinally pronounced systemic mast cell activation disorder. Scand J Gastroenterol, 42, pp. 1045-1053.
-
(2007)
Scand J Gastroenterol
, vol.42
, pp. 1045-1053
-
-
Molderings, G.J.1
Kolck, U.W.2
Scheurlen, C.3
Bruss, M.4
Homann, J.5
Von Kugelgen, I.6
-
66
-
-
0028181438
-
Expression of the Kit and KitA receptor isoforms in human acute myelogenous leukemia
-
Piao, X., Curtis, J. E., Minkin, S., Minden, M. D. and Bernstein, A. (1994) Expression of the Kit and KitA receptor isoforms in human acute myelogenous leukemia. Blood, 83, pp. 476-481.
-
(1994)
Blood
, vol.83
, pp. 476-481
-
-
Piao, X.1
Curtis, J.E.2
Minkin, S.3
Minden, M.D.4
Bernstein, A.5
-
67
-
-
1842579440
-
A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinib
-
Akin, C., Fumo, G., Yavuz, A. S., Lipsky, P. E., Neckers, L. and Metcalfe, D. D. (2004) A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinib. Blood, 103, pp. 3222-3225.
-
(2004)
Blood
, vol.103
, pp. 3222-3225
-
-
Akin, C.1
Fumo, G.2
Yavuz, A.S.3
Lipsky, P.E.4
Neckers, L.5
Metcalfe, D.D.6
-
68
-
-
0036968834
-
Apparent KIT Ser(715) deletion in GIST mRNA is not detectable in genomic DNA and represents a previously known splice variant of KIT transcript
-
Lasota, J., Kopczynski, J., Majidi, M., Miettinen, M. and Sarlomo-Rikala, M. (2002) Apparent KIT Ser(715) deletion in GIST mRNA is not detectable in genomic DNA and represents a previously known splice variant of KIT transcript. Am J Pathol, 161, pp. 739-741.
-
(2002)
Am J Pathol
, vol.161
, pp. 739-741
-
-
Lasota, J.1
Kopczynski, J.2
Majidi, M.3
Miettinen, M.4
Sarlomo-Rikala, M.5
-
69
-
-
3442901337
-
Systemic mastocytosis associated with acute myeloid leukemia: Case report and implications for disease pathogenesis
-
Escribano, L., Garca-Montero, A., Nunez-Lopez, R., Lopez-Jimenez, J., Almeida, J. Prados, A. et al. (2004) Systemic mastocytosis associated with acute myeloid leukemia: Case report and implications for disease pathogenesis. J Allergy Clin Immunol, 114, pp. 28-33.
-
(2004)
J Allergy Clin Immunol
, vol.114
, pp. 28-33
-
-
Escribano, L.1
Garca-Montero, A.2
Nunez-Lopez, R.3
Lopez-Jimenez, J.4
Almeida, J.5
Prados, A.6
|