Functional disturbances in the striatum by region-specific ablation of NMDA receptors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 35, 2008, Pages 12961-12966

  Ohtsuka, Nobuhisa ^a   Tansky, Morris F ^a   Kuang, Hui ^a,b   Kourrich, Saïd ^c   Thomas, Mark J ^c   Rubenstein, John L R ^d   Ekker, Marc ^e   Leeman, Susan E ^a   Tsien, Joe Z ^a,b  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Dopamine; Knockout; Locomotion; NR1; Striatum

Indexed keywords

DOPAMINE 1 RECEPTOR; DOPAMINE 1 RECEPTOR STIMULATING AGENT; DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR STIMULATING AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DYSFUNCTION; BRAIN ELECTROPHYSIOLOGY; BRAIN REGION; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC ACTIVITY; DOPAMINERGIC TRANSMISSION; FEMALE; FOOD INTAKE; GENETIC ENGINEERING; GROWTH RETARDATION; IN VIVO STUDY; LETHALITY; LOCOMOTION; MALE; MOUSE; NONHUMAN; OSCILLATION; PERINATAL PERIOD; POSTNATAL GROWTH; PRIORITY JOURNAL;

ACTION POTENTIALS; ANIMALS; ANIMALS, NEWBORN; ELECTROPHYSIOLOGY; GENE DELETION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; NEOSTRIATUM; ORGAN SPECIFICITY; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPTIC TRANSMISSION;

ANIMALIA; MUS;

EID: 51349095661     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0806180105     Document Type: Article

References (37)

1. McGeer PL, McGeer EG, Scherer U, Singh K (1977) A glutamatergic corticostriatal path? Brain Res 128:369-373.
2. Fonnum F, Storm-Mathisen J, Divac I (1981) Biochemical evidence for glutamate as neurotransmitter in corticostriatal and corticothalamic fibres in rat brain. Neuroscience 6:863-873.
3. Gerfen CR (1992) The neostriatal mosaic: Multiple levels of compartmental organization in the basal ganglia. Annu Rev Neurosci 15:285-320.
4. Kemp JM, Powell TP (1971) The structure of the caudate nucleus of the cat: Light and electron microscopy. Philos Trans R Soc Lond Ser B 262:383-401.
5. Albin RL, et al. (1992) Excitatory amino acid binding sites in the basal ganglia of the rat: A quantitative autoradiographic study. Neuroscience 46:35-48.
6. Standaert DG, Friberg IK, Landwehrmeyer GB, Young AB, Penney JB, Jr (1999) Expression of NMDA glutamate receptor subunit mRNAs in neurochemically identified projection and interneurons in the striatum of the rat. Brain Res Mol Brain Res 64:11-23.
7. Schambra UB, et al. (1994) Ontogeny of D1A and D2 dopamine receptor subtypes in rat brain using in situ hybridization and receptor binding. Neuroscience 62:65-85.
8. Hurst RS, Cepeda C, Shumate LW, Levine MS (2001) Delayed postnatal development of NMDA receptor function in medium-sized neurons of the rat striatum. Dev Neurosci 23:122-134.
9. Scott L, et al. (2002) Selective up-regulation of dopamine D1 receptors in dendritic spines by NMDA receptor activation. Proc Natl Acad Sci USA 99:1661-1664.
10. Scott L, et al. (2006) Allosteric changes of the NMDA receptor trap diffusible dopamine 1 receptors in spines. Proc Natl Acad Sci USA 103:762-767.
11. Pei L, Lee FJ, Moszczynska A, Vukusic B, Liu F (2004) Regulation of dopamine D1 receptor function by physical interaction with the NMDA receptors. J Neurosci 24:1149-1158.
12. Liu XY, et al. (2006) Modulation of D2R-NR2B interactions in response to cocaine. Neuron 52:897-909.
13. Li Y, Erzurumlu RS, Chen C, Jhaveri S, Tonegawa S (1994) Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice. Cell 76:427-437.
14. Forrest D, et al. (1994) Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death. Neuron 13:325-338.
15. Ghanem N, et al. (2003) Regulatory roles of conserved intergenic domains in vertebrate Dlx bigene clusters. Genome Res 13:533-543.
16. Tsien JZ, Huerta PT, Tonegawa S (1996) The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell 87:1327-1338.
17. Kobayashi M, et al. (2004) Simultaneous absence of dopamine D1 and D2 receptor-mediated signaling is lethal in mice. Proc Natl Acad Sci USA 101:11465-11470.
18. Zhou QY, Palmiter RD (1995) Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic. Cell 83:1197-1209.
19. Kreitzer AC, Malenka RC (2007) Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease models. Nature 445:643-647.
20. Cull-Candy S, Kelly L, Farrant M (2006) Regulation of Ca2+-permeable AMPA receptors: Synaptic plasticity and beyond. Curr Opin Neurobiol 16:288-297.
21. Lin L, et al. (2006) Large-scale neural ensemble recording in the brains of freely behaving mice. J Neurosci Methods 155:28-38.
22. Misgeld U, Okada Y, Hassler R (1979) Locally evoked potentials in slices of rat neostriatum: A tool for the investigation of intrinsic excitatory processes. Exp Brain Res 34:575-590.
23. Ryan LJ, Tepper JM, Young SJ, Groves PM (1986) Frontal cortex stimulation evoked neostriatal potentials in rats: Intracellular and extracellular analysis. Brain Res Bull 17:751-758.
24. Masimore B, Schmitzer-Torbert NC, Kakalios J, Redish AD (2005) Transient striatal gamma local field potentials signal movement initiation in rats. NeuroReport 16:2021-2024.
25. Cui Z, et al. (2004) Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain. Neuron 41:781-793.
26. Dang MT, et al. (2006) Disrupted motor learning and long-term synaptic plasticity in mice lacking NMDAR1 in the striatum. Proc Natl Acad Sci USA 103:15254-15259.
27. Heusner CL, Palmiter RD (2005) Expression of mutant NMDA receptors in dopamine D1 receptor-containing cells prevents cocaine sensitization and decreases cocaine preference. J Neurosci 25:6651-6657.
28. Kelley AE (2004) Ventral striatal control of appetitive motivation: Role in ingestive behavior and reward-related learning. Neurosci Biobehav Rev 27:765-776.
29. Stratford TR, Kelley AE (1999) Evidence of a functional relationship between the nucleus accumbens shell and lateral hypothalamus subserving the control of feeding behavior. J Neurosci 19:11040-11048.
30. Jicha GA, Salamone JD (1991) Vacuous jaw movements and feeding deficits in rats with ventrolateral striatal dopamine depletion: Possible relation to parkinsonian symptoms. J Neurosci 11:3822-3829.
31. Salamone JD, Mahan K, Rogers S (1993) Ventrolateral striatal dopamine depletions impair feeding and food handling in rats. Pharmacol Biochem Behav 44:605-610.
32. Jung AB, Bennett JP, Jr (1996) Development of striatal dopaminergic function. I. Pre- and postnatal development of mRNAs and binding sites for striatal D1 (D1a) and D2 (D2a) receptors. Brain Res Dev Brain Res 94:109-120.
33. David HN, Ansseau M, Abraini JH (2005) Dopamine-glutamate reciprocal modulation of release and motor responses in the rat caudate-putamen and nucleus accumbens of "intact" animals. Brain Res Brain Res Rev 50:336-360.
34. Bevan MD, Atherton JF, Baufreton J (2006) Cellular principles underlying normal and pathological activity in the subthalamic nucleus. Curr Opin Neurobiol 16:621-628.
35. Rampon C, et al. (2000) Enrichment induces structural changes and recovery from nonspatial memory deficits in CA1 NMDAR1-knockout mice. Nat Neurosci 3:238-244.
36. Tsien JZ, et al. (1996) Subregion- and cell type-restricted gene knockout in mouse brain. Cell 87:1317-1326.
37. Thomas MJ, Beurrier C, Bonci A, Malenka RC (2001) Long-term depression in the nucleus accumbens: A neural correlate of behavioral sensitization to cocaine. Nat Neurosci 4:1217-1223.