New multicomponent bioerodible electrospun nanofibers for dual-controlled drug release

Journal of Bioactive and Compatible Polymers

Volumn 23, Issue 5, 2008, Pages 423-443

  Piras, A M ^a   Chiellini, F ^a   Chiellini, E ^a   Nikkola, L ^b   Ashammakhi, N ^b  

^a UNIVERSITY OF PISA   (Italy)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

Drug release; Electrospinning; Nanofibers; Nanotechnology

Indexed keywords

ABS RESINS; DIELECTRIC RELAXATION; ETHERS; FIBERS; MALEIC ANHYDRIDE; NANOFIBERS; ORGANIC COMPOUNDS; SODIUM;

DRUG RELEASE; ELECTROSPINNING; MULTI COMPONENTS; NANOTECHNOLOGY;

NANOSTRUCTURED MATERIALS;

DICLOFENAC; HUMAN SERUM ALBUMIN; NANOFIBER; NANOMATERIAL; POLY(MALEIC ANHYDRIDE ALT 2 METHOXYETHYLVINYLETHER)BUTYL HEMIESTER; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL MODEL; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG POTENCY; DRUG RELEASE; DRUG STRUCTURE; ELECTROSPRAY; HYDROPHOBICITY; NANOTECHNOLOGY; SCANNING ELECTRON MICROSCOPY;

EID: 51349084060     PISSN: 08839115     EISSN: 15308030     Source Type: Journal    
DOI: 10.1177/0883911508093357     Document Type: Article

References (40)

1. Chew, S.Y., Wen, J., Yim, E.K.F. and Leong, K.W. (2005). Sustained Release of Proteins from Electrospun Biodegradable Fibers, Biomacromolecules, 6: 2017-2024.
2. Li, C., Vepari, C., Jin, H.J., Kim, H.J. and Kaplan, D.L. (2006). Electrospun silk-BMP-2 Scaffolds for Bone Tissue Engineering, Biomaterials, 27: 3115-3124.
3. Ashammakhi, N., Ndreu, A., Piras, A., Nikkola, L., Sindelar, T., Ylikauppila, H., et al. (2007). Biodegradable Nanomaterials Produced by Electrospinning: Expanding Multifunctionality and Potential for Tissue Engineering, J. Nanosci. Nanotechnol., 7 (3). 862-887.
4. Saltzman, W.M. and Olbricht, W.L. (2002). Building Drug Delivery Into Tissue Engineering, Nat. Rev. Drug. Discov., 1: 177-186.
5. Ikada, Y. and Tsuji, H. (2000). Biodegradable Polyesters for Medical and Ecological Applications, Macromol. Rapid Commun., 21: 117-132.
6. Kohn, J., Langer, R., Ratner, B.D., Hoffman, A.S., Schoen, F.J. and Lemons, J.E. (1996). Biomaterials Science, pp. 64-73, Academic Press Ed., San Diego, CA, USA.
7. Spasova, M., Stoilova, O., Manolova, N., Rashkov, I. and Altankov, G. (2007). Preparation of PLLA/PEG Nanofibers by Electrospinning and Potential Applications, J. Bioact. Compatible Polym., 22: 62-76.
8. Griffith, L.G. (2002). Emerging Design Principles in Biomaterials and Scaffolds for Tissue Engineering, Ann. N.Y. Acad. Sci., 961: 83-95.
9. Chiellini, E. and Solaro, R. (1995). Multifunctional Bioerodible/ Biodegradable Polymeric Materials, Macromolecular Symposia, 98: 803-824.
10. Choi, J.S. and Hyuk Sang Yoo, H.S. (2007). Electrospun Nanofibers Surface-modified with Fluorescent Proteins, J. Bioact. Compatible Polym., 22: 508-524.
11. Zeng, J., Aigner, A., Czubayko, F., Kissel, T., Wendorff, J.H. and Greiner, A. (2005). Poly(vinyl alcohol) Nanofibers by Electrospinning as a Protein Delivery System and the Retardation of Enzyme Release by Additional Polymer Coatings, Biomacromolecules, 6: 1484-1488.
12. Yang, F., Murugan, R., Wang, S. and Ramakrishna, S. (2005). Electrospinning of Nano/Micro Scale poly(L-lactic acid) Aligned Fibers and Their Potential in Neural Tissue Engineering, Biomaterials, 26: 2603-2610.
13. Tuzlakoglu, K., Bolgen, N., Salgado, A.J., Gomes, M.E., Piskin, E. and Reis, R.L. (2005). Nano- and Micro-fiber Combined Scaffolds: A New Architecture for Bone Tissue Engineering, J. Mater. Sci. Mater. Med., 16: 1099-1104.
14. Li, M., Mondrinos, M.J., Gandhi, M.R., Ko, F.K., Weiss, A.S. and Lelkes, P.I. (2005). Electrospun Protein Fibers as Matrices for Tissue Engineering, Biomaterials, 26: 5999-6008.
15. Jayaraman, K., Kotaki, M., Zhang, Y.Z., Mo, X.M. and Ramakrishna, S. (2004). Recent Advances in Polymer Nanofibers, J. Nanosci. Nanotechnol., 4: 52-65.
16. Deitzel, J.M., Kleinmeyer, J., Harris, D. and Beck, Tan, N.C. (2001). The Effect of Variables on the Morphology of Electrospun Nanofibers and Textiles, Polymer, 42: 261-272.
17. Pham, Q.P., Sharma, U. and Mikos, A.G. (2006). Electrospinning of Polymeric Nanofibers for Tissue Engineering Applications: A Review, Tissue Eng., 12: 1197-1211.
18. Deitzel, J.M., Kleinmeyer, J.D., Hiervonen, J.K. and Beck Tan, N.C. (2001). Controlled Deposition of Electronspun Poly(ethylene oxide) Fibers, Polymer, 42: 8163-8170.
19. Jiang, H., Fang, D., Hsiao, B., Chu, B. and Chen, W. (2004). Preparation and Characterization of Ibuprofen-loaded Poly(lactide-co-glycolide)/ poly(ethylene glycol) - γ-Chitosan Electrospun Membranes, J. Biomater. Sci. Polym. Ed., 15: 279-296.
20. Jiang, H., Hu, Y., Li, Y., Zhao, P., Zhu, K. and Chen, W. (2005). A Facile Technique to Prepare Biodegradable Coaxial Electrospun Nanofibers for Controlled Release of Bioactive Agents, J. Control. Release, 108: 237-243.
21. Solaro, R., Chiellini, F., Signori, F., Fiumi, C., Bizzarri, R. and Chiellini, E. (2003). Nanoparticle Systems for the Targeted Release of Active Principles of Proteic Nature, J. Mater. Sci. Mater. Med., 14: 705-711.
22. Chiellini, E.E., Chiellini, F. and Solaro, R. (2006). Bioerodible Polymeric Nanoparticles for Targeted Delivery of Proteic Drugs, J. Nanosci. Nanotechnol., 6: 3040-3047.
23. Huolma, R. and Ashammakhi, N. (2007). Novel Multifunctional Clodronate Releasing PLGA 80/20 Rods, J. Craniofac. Surg., 18 (2). 295-301.
24. Viitanen, P., Suokas, E., Törmälä, P. and Ashammakhi, N. (2006). Release of Diclofenac Sodium from Polylactide-co-glycolide 80/20 Rods, J. Mater. Sci. Mater. Med., 17 (12). 1267-1274.
25. Niemela, S.-M., Lansman, S., Ikaheimo, I., Koskela, M., Veiranto, M., Suokas, E. et al. (2006). Self-Reinforced Ciprofloxacin-Releasing Polylactide-co-Glycolide 80/20 Inhibits Attachment and Biofilm Formation by Staphylococcus Epidermidis: An in vitro Study, J. Craniofac. Surg., 17: 950-956.
26. Piras, A.M., Nikkola, L., Chiellini, F., Ashammakhi, N. and Chiellini, E. (2006). Development of Diclofenac Sodium Releasing Bio-Erodible Polymeric Nanomaterials, J. Nanosci. Nanotechnol., 6: 3310-3320.
27. Nikkola, L., Seppälä, J., Harlin, A., Ndreu, A. and Ashammakhi, N. (2006). Electrospun Multifunctional Diclofenac Sodium Releasing Nanoscaffold, J. Nanosci. Nanotechnol., 6: 3290-3295.
28. Chiellini, E., Leonardi, G., Giannasi, D. and Solaro, R. (1992). Partial Esters of Alternating Copolymers of Maleic Anhydride and Alkyl Vinyl Ethers for Pharmaceutical Applications, J. Bioact. Compat. Polym., 7: 161-174.
29. Chiellini, E. and Saettone, M.F. (1988). Polymer Drug Delivery Systems in Ophthalmic Applications, J. Bioact. Compat. Polym., 3: 86-93.
30. Saettone, M.F., Giannaccini, B., Leonardi, G., Monti, D., Chetoni, P., Galli, G. et al. (1988). Inserts for sustained Ocular Delivery of Pilocarpine: Evaluation of a Series of Partial Esters of (Maleic Acid - Alkyl Vinyl Ether) Alternating Copolymers, In: Migliaresi, C., Nicolais, L., Giusti, P. and Chiellini, E. (Eds), Polymers in Medicine III: Biomedical and Pharmaceutical Applications, pp. 209-224, Elsevier, Amsterdam, NL.
31. Chiellini, E., Solaro, R., Leonardi, G., Giannasi, D., Lisciani, R. and Mazzanti, G. (1992). New Polymeric Hydrogel Formulations for the Controlled Release of α-Interferon, J. Control. Rel., 22: 273-282.
32. Chiellini, E., Chiellini, E.E., Chiellini, F. and Solaro, R. (2001). Targeted Administration of Proteic Drugs. I. Preparation of Polymeric Nanoparticles, J. Bioact. Compat. Polym., 16: 441-465.
33. Chiellini, F., Piras, A.M., Gazzarri, M., Bartoli, C., Ferri, M. and Paolini, L. (2008). Bioactive Polymeric Materials for Targeted Administration of Active Agents - Synthesis and Evaluation Macromolecular Bioscience, doi:10.1002/ mabi.200700228.
34. Piras, A.M., Chiellini, F., Fiumi, C., Bartoli, C., Chiellini, E., Fiorentino, B. and Farina, C. (2008). A New Biocompatible Nanoparticle Delivery System for the Release of Fibrinolytic Drugs, Int J Pharm 357: 260-271.
35. Piras, AM, Dessy, A., Chiellini, F., Chiellini, E., Farina, C., Ramelli, M. and Della Valle, E. (2008). Polymeric Nanoparticles for Hemoglobin-Based Oxygen Carriers BBA - Proteins and Proteomics Special Issue. BBAPAP37914.
36. Subbiah, T., Bhat, G.S., Tock, R.W., Parameswaran, S. and Ramkumar, S.S. (2005). Electrospinning of Nanofibers, J. Appl. Polym. Sci., 96: 557-569.
37. Villiers, C., Braud, C., Vert, M., Chiellini, E. and Marchetti, M. (1978). Optically Active Alternating Copolymers of Maleic Acid and Alkylvinylethers, Eur. Polym., 14: 211-217.
38. Villiers, C., Braud, C., Vert, M. and Chiellini, E. (1979). Optically Active Polyelectrolytes with Variable Hydrophobicity. 3. Effects of pH-Induced Chromophore and Conformation Changes on Chiroptical Properties of Alternating Copolymers of Maleic Acid and Optically Active 1-Methylalkyl Vinyl Ethers, Macromolecules, 12: 103-107.
39. Yoshimoto, H., Shin, Y.M., Terai, H. and Vacanti, J.P. (2003). A Biodegradable Nanofiber Scaffold by Electrospinning and its Potential for Bone Tissue Engineering, Biomaterials, 24: 2077-2082.
40. Verreck, G., Chun, I., Rosenblatt, J., Peeters, J., Van Dijck, A., Mensch, J., Noppe, M. and Brewster, M.E. (2003). Incorporation of Drugs in an Amorphous State into Electrospun Nanofibers Composed of a Water-insoluble, Nonbiodegradable Polymer, J. Control. Release, 92: 349-360.