Prolificacy and lamb survival at birth in Awassi and Assaf sheep carrying the FecB (Booroola) mutation

Animal Reproduction Science

Volumn 108, Issue 3-4, 2008, Pages 402-411

  Gootwine, Elisha ^a   Reicher, Shay ^a   Rozov, Alexander ^a  

^a VOLCANI CENTER   (Israel)

Author keywords

Assaf; Awassi; Booroola; FecB; Sheep

Indexed keywords

BONE MORPHOGENETIC PROTEIN RECEPTOR 1; DNA;

ALLELE; ANIMAL; ANIMAL DISEASE; ARTICLE; CHEMISTRY; CROSS BREEDING; FEMALE; GENETICS; GENOTYPE; LITTER SIZE; MALE; MUTATION; NEWBORN; POLYMERASE CHAIN REACTION; PREGNANCY; REGRESSION ANALYSIS; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SHEEP; SURVIVAL;

ALLELES; ANIMALS; ANIMALS, NEWBORN; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; CROSSES, GENETIC; DNA; FEMALE; GENOTYPE; LEAST-SQUARES ANALYSIS; LITTER SIZE; MALE; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PREGNANCY; SHEEP; SURVIVAL ANALYSIS;

OVIS ARIES;

EID: 51249092373     PISSN: 03784320     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anireprosci.2007.09.009     Document Type: Article

References (38)

1. Chu M.X., Liu Z.H., Jiao C.L., He Y.Q., Fang L., Ye S.C., Chen G.H., and Wang J.Y. Mutations in BMPR-IB and BMP-15 genes are associated with litter size in Small Tailed Han sheep (Ovis aries). J. Anim. Sci. 85 (2007) 598-603
2. Davis G.H., Balakrishnan L., Ross I.K., Wilson T., Galloway S.M., Lumsden B.M., Hanrahan J.P., Mullen M., Mao X.Z., Wang G.L., Zhao Z.S., Zeng Y.Q., Robinson J.J., Mavrogenis A.P., Papachristoforou C., Peter C., Baumung R., Cardyn P., Boujenane I., Cockett N.E., Eythorsdottir E., Arranz J.J., and Notter D.R. Investigation of the Booroola (FecB) and Inverdale (FecX(I)) mutations in 21 prolific breeds and strains of sheep sampled in 13 countries. Anim. Reprod. Sci. 92 (2006) 87-96
3. Davis G.H., Elsen J.M., Bodin L., Fahmy M., Castonguay F., Gootwine E., Bor A., Braw-Tal R., Greef J.F., Lengyel A., Paszthy F., and Cummins L. A Comparison of the Production from Booroola and Local Breed Sheep in Different Countries. In: Elsen J.M., Bodin L., and Thimonier J. (Eds). Major Genes for Reproduction in Sheep (1991), INRA, Paris 315-323
4. Davis G.H., Galloway S.M., Ross I.K., Gregan S.M., Ward J., Nimbkar B.V., Ghalsasi P.M., Nimbkar C., Gray G.D., Subandriyo, Inounu I., Tiesnamurti B., Martyniuk E., Eythorsdottir E., Mulsant P., Lecerf F., Hanrahan J.P., Bradford G.E., and Wilson T. DNA tests in prolific sheep from eight countries provide new evidence on origin of the Booroola (FecB) mutation. Biol. Reprod. 66 (2002) 1869-1874
5. Dodds K.G., Davis G.H., Elsen J.M., Isaacs K.L., and Owens J.L. The effect of Booroola genotype on some reproductive traits in a Booroola Merino Flock. In: Elsen J.M., Bodin L., and Thimonier J. (Eds). Major Genes for Reproduction in Sheep (1990), INRA, Toulouse 359-366
6. Epstein, H., 1985. The Awassi sheep with special reference to the improved dairy type. Animal Production and Health Paper No. 57. FAO, Rome.
7. Farquhar P.A., Dodds K.G., and Davis G.H. Introgression of the Booroola mutation (FecB) leads to hyper-prolificacy in a Romney sheep flock. 8th World Congress on Genetics Applied to Livestock Production. Belo Horizonte, MG, Brazil (2006)
8. Fogarty N., Hopkins D., and van der Van R. Lamb production from diverse genotypes. 1. Lamb growth and survival and ewe performances. Animal Sci. 70 (2000) 135-145
9. Gama L., Dickerson G., Young L., and Leymaster K.A. Effect of breed, heterosis, age of dam, litter size and birth weight on lamb mortality. J. Anim. Sci. 69 (1991) 2727-2734
10. Gootwine E. Variability in the rate of decline in birth weight as litter size increases in sheep. Animal Sci. 81 (2005) 393-398
11. Gootwine E., Bor A., Braw-Tal R., and Zenou A. Reproductive performance and milk production of the improved Awassi breed as compared to its crosses with the Booroola Merino. Animal Sci. 60 (1995) 109-115
12. Gootwine E., Braw-Tal R., Shalhevet D., Bor A., and Zenou A. Reproductive performance of Assaf and Booroola-Assaf crossbred ewes and its association with plasma FSH levels and induced ovulation rate measured at pre-puberty. Anim. Reprod. Sci. 9 (1993) 145-151
13. Gootwine E., and Pollott G.E. Factors affecting milk production in improved Awassi dairy ewes. Animal Sci. 71 (2000) 607-615
14. Gootwine E., and Rozov A. Seasonal effects on birth weight of lambs born to prolific ewes maintained under intensive management. Livest. Prod. Sci. 105 (2006) 277-283
15. Gootwine, E., Rozov, A., Bor, A., Reicher, S., 2003. Effects of the FecB (Booroola) gene on reproductive and productive traits in the Assaf breed. In: Proceedings of the International Workshop on Major Genes and QTL in Sheep and Goats. Toulouse, CD-ROM communication no. 2-12, p. 4.
16. Gootwine E., Rozov A., Bor A., and Reicher S. Carrying the FecB (Booroola) mutation is associated with lower birth weight and slower post weaning growth rate for lambs and lighter mature body weight for ewes. Reprod. Fertil. Dev. 18 (2006) 433-437
17. Gootwine E., Spencer T.E., and Bazer F.W. Litter-size-dependent intrauterine growth restriction in sheep. Animal 1 (2007) 547-564
18. Gootwine E., Zenou A., Bor A., Yossefi S., Rozov A., and Pollott G.E. Genetic and economic analysis of introgression of the B allele of the FecB (Booroola) gene into the Awassi and Assaf dairy breeds. Livest. Prod. Sci. 71 (2001) 49-58
19. Guan F., Liu S.R., Shi G.Q., and Yang L.G. Polymorphism of FecB gene in nine sheep breeds or strains and its effects on litter size, lamb growth and development. Anim. Reprod Sci. 99 (2007) 44-52
20. Hinch G., Crosbie S., Kelly R., Owens J., and Davis G.H. Influence of birth weight and litter size on lamb survival in high fecundity Booroola-Merino crossbred flocks. N. Z. J. Agric. Res. 28 (1985) 31-38
21. Kleemann D.O., and Walker S.K. Fertility in South Australian commercial merino flocks: source of reproductive wastage. Theriogenology 63 (2005) 2075-2088
22. Kumar S., Kolte A.P., Mishra A.K., Arora A.L., and Singh V.K. Identification of the FecB mutation in Garole × Malpura sheep and its effect on litter size. Small Rumin. Res. 64 (2006) 305-310
23. Kumar S., Mishra A.K., Kolte A.P., Arora A.L., Singh D., and Singh V.K. Effects of the Booroola (FecB) genotypes on growth performance, ewe's productivity efficiency and litter size in Garole × Malpura sheep. Anim. Reprod. Sci. 105 (2008) 319-331
24. Meyer H.H. Breed differences in ovulation rate and uterine efficiency and their contribution to fecundity. In: Land R.B., and Robinson D.W. (Eds). Genetics of Reproduction in Sheep (1985), Butterworths, London 185-191
25. Meyer H.H., Baker R.L., Harvey S.M., and Hickey S.M. Effects of Booroola Merino breeding and the FecB gene on performance of crosses with longwool breeds. 2. Effects on reproductive performance and weight of lamb weaned by young ewes. Livest. Prod. Sci. 39 (1994) 191-200
26. Mulsant P., Lecerf F., Fabre S., Schibler L., Monget P., Lanneluc I., Pisselet C., Riquet J., Monniaux D., Callebaut I., Cribiu E., Thimonier J., Teyssier J., Bodin L., Cognie Y., Chitour N., and Elsen J.M. Mutation in bone morphogenetic protein receptor-IB is associated with increased ovulation rate in Booroola Merino ewes. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 5104-5109
27. Piper L.R., Bindon B.M., and Davis G.H. The single gene inheritance of the high litter size of the Booroola Merino. In: Land R.B., and Robinson D.W. (Eds). Genetics of Reproduction in Sheep (1985), Butterworths, London 115-125
28. Pollott G.E., and Gootwine E. Reproductive performance and milk production of Assaf sheep in an intensive management system. J. Dairy Sci. 87 (2004) 3690-3703
29. Safari E., Fogarty N.M., and Gilmour A.R. A review of genetic parameter estimates for wool, growth, meat and reproduction traits in sheep. Livest. Prod. Sci. 92 (2005) 271-289
30. ®, User's Guide Version 5 (2001), SAS Institute, Duxbury, CA, USA
31. Schulze K.S., Waldron D.F., Willingham T.D., Shelby D.R., Engdahl G.R., Gootwine E., Yoshefi S., Montgomery G.M., Tate M., and Lord E.A. Effects of the FecB gene in half-sib families of Rambouillet-cross ewes. Sheep Goat Res. 18 (2003) 83-88
32. Southey B.R., Thomas D.L., Gottferedson R.G., and Zelinsky R.D. Ewe productivity of Booroola Merino-Rambouillet crossbred sheep during early stages of the introgression of the FecB allele into a Rambouillet population. Livest. Prod. Sci. 75 (2002) 33-44
33. Souza C.J., MacDougall C., Campbell B.K., McNeilly A.S., and Baird D.T. The Booroola (FecB) phenotype is associated with a mutation in the bone morphogenetic receptor type 1B (BMPR-1B) gene. J. Endocrinol. 2 (2001) R1-R6
34. Teyssier, J., Elsen, J.M., Bodin, L., Bouquet, P.M., Mulsant, P., Thimonier, J., 2003. The Booroola gene in Merinos D'Arles sSheep: introduction of the gene (FecB), productivity of FecB heterozygous carrier ewes under farm conditions. In: Proceedings of the International Workshop on Major Genes and QTL in Sheep and Goat, INRA, Toulouse, CD-ROM communication no. 2-13, p. 4.
35. Visscher A.H., and van Haandel B.B.P.G. Influence of Booroola F-gene on reproductive, growth and carcass characteristics in a Texel Flock. In: Elsen J.M., Bodin L., and Thimonier J. (Eds). Major Genes for Reproduction in Sheep (1991), INRA, Paris 391-396
36. Wilson T., Wu X.Y., Juengel J.L., Ross I.K., Lumsden J.M., Lord E.A., Dodds K.G., Walling G.A., McEwan J.C., O'Connell A.R., McNatty K.P., and Montgomery G.W. Highly prolific Booroola sheep have a mutation in the intracellular kinase domain of bone morphogenetic protein IB receptor (ALK-6) that is expressed in both oocytes and granulosa cells. Biol. Reprod. 64 (2001) 1225-1235
37. Young L.D., and Dickerson G.E. Comparison of Booroola Merino and Finnsheep: effects on productivity of mates and performance of crossbred lambs. J. Anim. Sci. 69 (1991) 1899-1911
38. Zamir S., Rozov A., and Gootwine E. Improving ewes' and lambs' survival in cases of pregnancy toxemia using Flunixin Meglumine. Hanoked (in Hebrew) 45 (2007) 20-23