Staged intrastromal delivery of riboflavin with UVA cross-linking in advanced bullous keratopathy: Laboratory investigation and first clinical case

Journal of Refractive Surgery

Volumn 24, Issue 7, 2008, Pages

  Krueger, Ronald R ^a   Ramos Esteban, Jerome C ^a   Kanellopoulos, A John ^b,c  

^a LERNER RESEARCH INSTITUTE   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Laservisiongr Institute   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

RIBOFLAVIN;

AGED; CASE REPORT; CONFERENCE PAPER; CORNEA EDEMA; CORNEA THICKNESS; CORNEA TRANSPLANTATION; CROSS LINKING; DRUG ADMINISTRATION ROUTE; FEMALE; HUMAN; HUMAN TISSUE; INTRASTROMAL DRUG ADMINISTRATION; KERATOPATHY; PRIORITY JOURNAL; ULTRAVIOLET A RADIATION;

EID: 51149115767     PISSN: 1081597X     EISSN: None     Source Type: Journal    
DOI: 10.3928/1081597x-20080901-17     Document Type: Conference Paper

References (15)

1. Rao GN, Aquavella JV, Goldberg SH, Berk SL. Pseudophakic bullous keratopathy. Relationship to preoperative corneal endothelial status. Ophthalmology. 1984;91:1135-1140.
2. Waltman SR. Penetrating keratoplasty for pseudophakic bullous keratopathy. Visual results. Arch Ophthalmol. 1981;99:415-416.
3. Koenig SB, Covert DJ, Dupps WJ Jr, Meisler DM. Visual acuity, refractive error, endothelial cell density six months after Descemet stripping and automated endothelial keratoplasty (DSAEK). Cornea. 2007;26:670-674.
4. Wollensak G, Spoerl E, Seiler T. Riboflavin/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol. 2003;135:620-627.
5. Mazzotta C, Traversi C, Baiocchi S, Sergio P, Caporossi T, Caporossi A. Conservative treatment of keratoconus by riboflavin-uva-induced cross-linking of corneal collagen: qualitative investigation. Eur J Ophthalmol. 2006;16:530-535.
6. Caporossi A, Baiocchi S, Mazzotta C, Traversi C, Caporossi T. Parasurgical therapy for keratoconus by riboflavin-ultraviolet type A rays induced cross-linking of corneal collagen: preliminary refractive results in an Italian study. J Cataract Refract Surg. 2006;32:837-845.
7. Kanellopoulos AJ. Collagen cross-linking (CCL) with sequential topography-guided PRK: a temporizing alternative for keratoconus to penetrating keratoplasty. Cornea. 2007;26:891-895.
8. Hafezi F, Kanellopoulos J, Wiltfang R, Seiler T. Corneal collagen crosslinking with riboflavin and ultraviolet A to treat induced keratectasia after laser in situ keratomileusis. J Cataract Refract Surg. 2007;33:2035-2040.
9. Kanellopoulos AJ. Post-LASIK ectasia. Ophthalmology. 2007;114:1230.
10. Spoerl E, Wollensak G, Seiler T. Increased resistance of cross-linked cornea against enzymatic digestion. Curr Eye Res. 2004;29:35-40.
11. Wollensak G, Iomdina E, Dittert DD, Salamatina O, Stoltenburg G. Cross-linking of scleral collagen in the rabbit using riboflavin and UVA. Acta Ophthalmol Scand. 2005;83:477-482.
12. Thornton IL, Dupps WJ, Krueger RR. Biomechanical effect of intraocular pressure elevation on optic nerve/lamina cribrosa before and after peripapillary scleral collagen crosslinking. Invest Ophthalmol Vis Sci. In press.
13. Wollensak G, Aurich H, Pham DT, Wirbelauer C. Hydration behavior of porcine cornea crosslinked with riboflavin and ultraviolet A. J Cataract Refract Surg. 2007;33:516-521.
14. Mazzotta C, Balestrazzi A, Baiocchi S, Traversi C, Caporossi A. Stromal haze after combined riboflavin-UVA corneal collagen cross-linking in keratoconus: in vivo confocal microscopic evaluation. Clin Experiment Ophthalmol. 2007;35:580-582.
15. Spoerl E, Mrochen M, Sliney D, Trokel S, Seiler T. Safety of UVA-riboflavin cross-linking of the cornea. Cornea. 2007;26:385-389.