CD117 in atypical fibroxanthoma: Tumor or stroma?

American Journal of Dermatopathology

Volumn 30, Issue 4, 2008, Pages 401-402

  Beer, Trevor William ^a  

^a Cutaneous Pathology ^*  (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CD68 ANTIGEN; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; PROTEIN S 100; STEM CELL FACTOR RECEPTOR; TRYPTASE; TUMOR MARKER;

ADULT; CASE REPORT; DENDRITIC CELL; ELECTRON MICROSCOPY; EPITHELIUM CELL; FIBROXANTHOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LANGERHANS CELL; LEIOMYOSARCOMA; LETTER; MALE; MAST CELL; MELANOCYTE; MERKEL CELL TUMOR; PRIORITY JOURNAL; SPINDLE CELL CARCINOMA; STROMA; TUMOR CELL; BIOSYNTHESIS; DERMATOFIBROMA; METABOLISM; NOTE; SKIN TUMOR; STROMA CELL;

HISTIOCYTOMA, BENIGN FIBROUS; HUMANS; IMMUNOHISTOCHEMISTRY; PROTO-ONCOGENE PROTEINS C-KIT; SKIN NEOPLASMS; STROMAL CELLS; TUMOR MARKERS, BIOLOGICAL;

EID: 51149101665     PISSN: 01931091     EISSN: None     Source Type: Journal    
DOI: 10.1097/DAD.0b013e318177e1b7     Document Type: Letter

References (6)

1. Mathew RA, Schlauder SM, Calder KB, et al. CD117 immunoreactivity in atypical fibroxan-thoma. Am J Dermatopathol. 2008;30:34-36.
2. Horie M, Hatomochi A, Yamazaki S, et al. A case of cutaneous leiomyosarcoma with over expression of KIT: do CD117 (KIT)-positive primary gastrointestinal stromal tumours of the skin exist? Br J Dermatol. 2006;154:1013-1016.
3. Swick BL, Ravdel L, Fitzpatrick JE, et al. Merkel cell carcinoma: evaluation of KIT(CD117) expression and failure to demonstrate activating mutations in the C-KIT proto-oncogene-implications for treatment with imatinib mesylate. J Cutan Pathol. 2007;34:324-329.
4. Chan JK. Mesenchymal tumors of the gastrointestinal tract: a paradise for acronyms (STUMP, GIST, GANT and now GIPACT), implication of c-kit in genesis, and yet another of the many emerging roles of the interstitial cell of Cajal in the pathogenesis of gastrointestinal diseases? Adv Anat Pathol. 1999;6:19-40.
5. Ricci A Jr, Cartun RW, Zakowski MF, et al. Atypical fibroxanthoma. A study of 14 cases emphasizing the presence of Langerhans' histio-cytes with implications for differential diagnosis by antibody panels. Am J Surg Pathol. 1988;12: 591-598.
6. Carson JW, Schwartz RA, McCandless CM Jr, et al. Atypical fibroxanthoma of the skin. Report of a case with Langerhans-like granules. Arch Dermatol. 1984;120:234-239.