Automation of Sample Dispensing Using Pocket Tips for Evaluation of CYP2C9 Isoenzyme Reversible Inhibition in an Evolution Precision Pipetting Platform

Journal of Laboratory Automation

Volumn 13, Issue 5, 2008, Pages 289-296

  Ramírez, Manuel ^a   Tudela, Consuelo ^a   Crespo, Juan B ^a   Rubles, Alicia ^a   Jiménez, Antonio ^a   Tarazona, Guillermo ^a   Fernández, Laura ^a   Sánchez, Pilar ^a   Kroncke, Doug ^b   Tabanera, Noemí ^a   Pérez, Joseé ^a   Sánchez, Manuel ^a   Tormo, José R ^a   Peláez, Fernando ^a  

^a Medical affairs Merck sharp and Dohme ltd   (Spain)

^b nAscent Biosciences   (United States)

Author keywords

CYP (cytochrome P 450) isoenzymes; PerkinElmer Evolution P3; PocketTips Technology; TECAN Spectra Fluor; TECAN Ultra Evolution; WinPREP software

Indexed keywords

ASSAYS; COMPUTER NETWORKS; CONCENTRATION (PROCESS); DIMETHYL SULFOXIDE; ELECTRONIC EQUIPMENT MANUFACTURE; ELECTRONICS PACKAGING; PROCESS ENGINEERING; RESEARCH LABORATORIES; SOLUTIONS; SOLVENTS; TITRATION; VOLUMETRIC ANALYSIS;

CYP (CYTOCHROME P-450) ISOENZYMES; PERKINELMER EVOLUTION P3; POCKETTIPS TECHNOLOGY; TECAN SPECTRA FLUOR; TECAN ULTRA EVOLUTION; WINPREP SOFTWARE;

ORGANIC SOLVENTS;

CYTOCHROME P450 2C9; DIMETHYL SULFOXIDE; ISOENZYME; SOLVENT;

ARTICLE; ASSAY; AUTOMATION; CONCENTRATION (PARAMETERS); ENZYME INHIBITION; EQUIPMENT; EVALUATION; IN VITRO STUDY; LABORATORY; LIQUID; PIPETTE; RADIOMETRY; ROBOTICS; SAMPLE; SAMPLING; SCREENING; SOLUBILITY; TITRIMETRY; VALIDATION PROCESS;

EID: 51149099568     PISSN: 22110682     EISSN: 15402452     Source Type: Journal    
DOI: 10.1016/j.jala.2008.06.003     Document Type: Article

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