Molecular cloning, tissue distribution and segmental ontogenetic regulation of b0,+ amino acid transporter in lantang pigs

Asian-Australasian Journal of Animal Sciences

Volumn 21, Issue 8, 2008, Pages 1134-1142

  Zhi, Ai Min ^a   Feng, Ding Yuan ^a   Zhou, Xiang Yan ^a   Zou, Shi Geng ^a   Huang, Zhi Yi ^a   Zuo, Jian Jun ^a   Ye, Hui ^a   Zhang, Chang Ming ^a   Dong, Ze Min ^a   Liu, Zhun ^a  

^a SOUTH CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

b0,+at; Cationic amino acid transporter; Ontogenetic regulation; SLC7A9

Indexed keywords

SUIDAE; SUS;

EID: 51149083652     PISSN: 10112367     EISSN: None     Source Type: Journal    
DOI: 10.5713/ajas.2008.80044     Document Type: Article

References (28)

1. Arriza, J. L., M. P. Kavanaugh, W. A. Fairman, Y. N. Wu, G. H. Murdoch, R. A. North and S. G Amara. 1993. Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family. J. Biol. Chem. 268:15329-15332.
2. Buddington, R. K., J. Elnif, A. A. Puchal-Gardiner and P. T. Sangild. 2001. Intestinal apical amino acid absorption during development of the pig. Am. J. Physiol. Regul. Integr. Comp. Physiol. 280:241-247.
3. Chairoungdua, A., H. Segawa, J. Y. Kim, K.-I. Miyamoto, H. Haga, Y. Fukui, K. I. Mizoguchi, H. Ito, E. Takeda, H. Endou, Y. Kanai. 1999. Identification of an amino acid transporter associated with the cystinuria-related type II membrane glycoprotein. J. Biol. Chem. 274:28845-28848.
4. Chaudhry, F. A., R. J. Reimer, D. Krizaj, D. Barber, J. Storm-Mathisen, D. R. Copenhagen and A. R. H. Edwards. 1999. Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission farrukh a chaudhry. Cell. 99:769-780.
5. +L-like. A tertiary active transport mechanism for renal reabsorption of cystine and dibasic amino acids. J. Biol. Chem. 271:17761-17770.
6. Chillaron, J., R. Roca, A. Valencia, A. Zorzano and M. Palacin. 2001. Heteromeric amino acid transporters: biochemistry, genetics, and physiology. Am. J. Physiol. Renal. Physiol. 281:995-1018.
7. de Castro, E., C. J. A. Sigrist, A. Gattiker, V. Bulliard, P. S. Langendijk-Genevaux, E. Gasteiger, A. Bairoch, N. Hulo. 2006. ScanProsite: detection of PROSITE signature matches and pro rule-associated functional and structural residues in proteins. Nucl. Acids Res. 34:362-365.
8. 0,+AT) of rBAT. Nat.Genet. 23:52-57.
9. Font-Llitjos, M., L. Feliubadalo, M. Espino, R. Clerics, S. Manas, I. M. Frey, S. Puertas, G Colell, S. Palomo, J. Aranda, J. Visa, M. Palacin and V. Nunes. 2007. Slc7a9 knockout mouse is a good cystinuria model for antilithiasic pharmacological studies. Am. J. Physiol. Renal. Physio. 293:732-740.
10. Font, M., L. Feliubadalo, X. Estivill, V. Nunes, E. Golomb, Y. Kreiss, E. Pras, L. Bisceglia, A. P. d'Adamo, L. Zelante, P. Gasparini, M. T. Bassi, A. L. George, Jr., M. Manzoni, M. Riboni, A. Ballabio, G Borsani, N. Reig, E. Fernandez, A. Zorzano, J. Bertran and M. Palacin. 2001. Functional analysis of mutations in SLC7A9, and genotype-phenotype correlation in non-type I cystinuria. Hum. Mol. Genet. 10:305-316.
11. Johnson, L. R. 1997. Page 130 in Gastrointestinal Physiology, 6th ed. Mosby Inc. St. Louis, MI.
12. Kanail, Y. and H. Endoul. 2001. Heterodimeric amino acid transporters: molecular biology and pathological and pharmacological relevance. Curr. Drug. Metab. 2:339-354.
13. 0 from a human placenta! choriocarcinoma cell line. J. Biol. Chem. 271:18657-18661.
14. 0. Am. J. Physiol. Gastrointest Liver Physiol. 272:1463-1472.
15. Krogh, A., B. Larsson, G V. Heijne and E. L. L. Sonnhammer. 2001. Predicting transmembrane protein topology with a hidden markov model: application to complete genomes. J. Molec. Biol. 305:567-580.
16. -ΔCT method. Methods 25:402-408.
17. Mastroberardino, L., B. Spindler, R. Pfeiffer, P. J. Skelly, J. Loffing, C. B. Shoemaker and F. Verrey. 1998. Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family. Nature 395(6699):288-291.
18. 0,+, XAG and ASC in swine small intestine. Comp. Biochem. Physiol. A Mol. Integr. Physiol. 126:527-537.
19. Palacin, M., R. Estevez, J. Bertran and A. Zorzano. 1998. Molecular biology of mammalian plasma membrane amino acid transporters. Physiol. Rev. 78:969-1054.
20. Pfeiffer, R., B. Spindler, J. Loffing, P. J. Skelly, C. B. Shoemaker and F. Verrey. 1998. Functional heterodimeric amino acid transporters lacking cysteine residues involved in disulfide bond. FEBS. 439:157-162.
21. Pfeiffer, R., J. Loffing, G Rossier, C. Bauch, C. Meier, T. Eggermann, D. Loffing-Cueni, L. C. Kuhn and F. Verrey. 1999. Luminal heterodimeric amino acid transporter defective in cystinuria. Mol. Biol. Cell 10:4135-4147.
22. 0,+-like amino acid transporter functioning as a heterodimer with 4F2hc instead of rBAT. A new candidate gene for cystinuria. J. Biol. Chem. 274:29005-29010.
23. 0,+ is fully functional in the absence of the heavy subunit. The EMBO J. 21:4906-4914.
24. Shi-bin Yuan, Dai-wen Chen, K.-Y. Zhang and B. Yu. 2007, Effects of oxidative stress on growth performance, nutrient digestibilities and activities of antioxidative enzymes of weanling pigs. Asian-Aust. J. Anim. Sci. 20:1600-1605.
25. +-independent transport of basic and zwitterionic amino acids in mouse blastocysts by a shared system and by processes which distinguish between these substrates. J. Biol. Chem. 263:3150-3163.
26. Varoqui, H., H. Zhu, D. Yao, H. Ming and J. D. Erickson. 2000. Cloning and functional identification of a neuronal glutamine transporter. J. Biol. Chem. 275:4049-4054.
27. Wagner, C. A., F. Lang and S. Broer. 2001. Function and structure of heterodimeric amino acid transporters. Am. J. Physiol. Cell Physiol. 281:1077-1093.
28. Wang, J. F., T. Lundh, B. Westrm and J. E. Lindberg. 2005. The Effect of complementary access to milk replacer to piglets on the activity of brush border enzymes in the piglet small intestine. Asian-Aust. J. Anim. Sci. 18:1617-1622.