GTP binding is required for SEPT12 to form filaments and to interact with SEPT11

Molecules and Cells

Volumn 25, Issue 3, 2008, Pages 385-389

  Ding, Xiangming ^a   Yu, Wenbo ^a   Liu, Ming ^a   Shen, ShuQing ^a   Chen, Fang ^a   Cao, Lihuan ^a   Wan, Bo ^a   Yu, Long ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Co localization; GTP binding domain; Protein interaction; Septin; Subcellular localization

Indexed keywords

ASPARAGINE; GLYCINE; GUANINE NUCLEOTIDE BINDING PROTEIN; SEPTIN; SEPTIN 12; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; GUANOSINE TRIPHOSPHATE; SEPT11 PROTEIN, HUMAN; SEPT12 PROTEIN, HUMAN;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE EXPRESSION; GENE INTERACTION; GENE MUTATION; HELA CELL; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; NUCLEOTIDE SEQUENCE; PROTEIN AGGREGATION; PROTEIN PROTEIN INTERACTION; TRANSIENT EXPRESSION; WILD TYPE; GENETICS; METABOLISM; MUTATION; ULTRASTRUCTURE;

MAMMALIA;

CELL CYCLE PROTEINS; GTP-BINDING PROTEINS; GUANOSINE TRIPHOSPHATE; HELA CELLS; HUMANS; MUTATION;

EID: 51049124338     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Adam, J.C., Pringle, J.R., and Peifer, M. (2000). Evidence for functional differentiation among Drosophila septins in cytokinesis and cellularization. Mol. Biol. Cell. 11, 3123-3135.
2. Beites, C.L., Xie, H., Bowser, R., and Trimble, W.S. (1999). The septin CDCrel-1 binds syntaxin and inhibits exocytosis. Nat. Neurosci. 2, 434-439.
3. Blaser, S., Horn, J., Wurmell, P., Bauer, H., Strumpell, S., Nurden, P., Pagenstecher, A., Busse, A., Wunderle, D., Hainmann, I., et al. (2004). The novel human platelet septin SEPT8 is an interaction partner of SEPT4. Thromb. Haemost. 91, 959-966.
4. Blaser, S., Roseler, S., Rempp, H., Bartsch, I., Bauer, H., Lieber, M., Lessmann, E., Weingarten, L., Busse, A., Huber, M., et al. (2006). Human endothelial cell septins: SEPT11 is an interaction partner of SEPT5. J. Pathol. 210, 103-110.
5. Cooper, J.A., and Kiehart, D.P. (1996). Septins may form a ubiquitous family of cytoskeletal filaments. J. Cell Biol. 134, 1345-1348.
6. Field, C.M., al-Awar, O., Rosenblatt, J., Wong, M.L., Alberts, B., and Mitchison, T.J. (1996). A purified Drosophila septin complex forms filaments and exhibits GTPase activity. J. Cell Biol. 133, 605-616.
7. Field, C.M., and Kellogg, D. (1999). Septins: cytoskeletal polymers or signalling GTPases? Trends Cell Biol. 9, 387-394.
8. Hall, P.A., Jung, K., Hillan, K.J., and Russell, S.E. (2005). Expression profiling the human septin gene family. J. Pathol. 206, 269-278.
9. Hanai, N., Nagata, K., Kawajiri, A., Shiromizu, T., Saitoh, N., Hasegawa, Y., Murakami, S., and Inagaki, M. (2004). Biochemical and cell biological characterization of a mammalian septin, Sept11. FEBS Lett. 568, 83-88.
10. Hartwell, L.H. (1971). Genetic control of the cell division cycle in yeast. IV. Genes controlling bud emergence and cytokinesis. Exp. Cell Res. 69, 265-276.
11. Hsu, S.C., Hazuka, C.D., Roth, R., Foletti, D.L., Heuser, J., and Scheller, R.H. (1998). Subunit composition, protein interactions, and structures of the mammalian brain sec6/8 complex and septin filaments. Neuron 20, 1111-1122
12. Ihara, M., Tomimoto, H., Kitayama, H., Morioka, Y., Akiguchi, I., Shibasaki, H., Noda, M., and Kinoshita, M. (2003). Association of the cytoskeletal GTP-binding protein Sept4/H5 with cytoplasmic inclusions found in Parkinson's disease and other synucleinopathies. J. Biol. Chem. 278, 24095-24102.
13. Kinoshita, M. (2003). Assembly of mammalian septins. J. Biochem. (Tokyo). 134, 491-496.
14. Kinoshita, M., Field, C.M., Coughlin, M.L., Straight, A.F., and Mitchison, T.J. (2002). Self- and actin-templated assembly of Mammalian septins. Dev. Cell. 3, 791-802.
15. Kinoshita, M., Kumar, S., Mizoguchi, A., Ide, C., Kinoshita, A., Haraguchi, T., Hiraoka, Y., and Noda, M. (1997). Nedd5, a mammalian septin, is a novel cytoskeletal component interacting with actin-based structures. Genes Dev. 11, 1535-1547.
16. Larisch, S., Yi, Y., Lotan, R., Kerner, H., Eimerl, S., Tony Parks, W., Gottfried, Y., Birkey, Reffey S., de Caestecker, M.P., Danielpour, D., et al. (2000). A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its Ploop motif. Nat. Cell Biol. 2, 915-921.
17. Martinez, C., Sanjuan, M.A., Dent, J.A., Karlsson, L., and Ware, J. (2004). Human septin-septin interactions as a prerequisite for targeting septin complexes in the cytosol. Biochem. J. 382, 783-791.
18. McIlhatton, M.A., Burrows, J.F., Donaghy, P.G., Chanduloy, S., Johnston, P.G., and Russell, S.E. (2001). Genomic organization, complex splicing pattern and expression of a human septin gene on chromosome 17q25.3. Oncogene 20, 5930-5939.
19. Mendoza, M., Hyman, A.A., and Glotzer, M. (2002). GTP binding induces filament assembly of a recombinant septin. Curr. Biol. 12, 1858-1863.
20. Nagata, K., Asano, T., Nozawa, Y., and Inagaki, M. (2004). Biochemical and cell biological analyses of a mammalian septin complex, Sept7/9b/11. J. Biol. Chem. 279, 55895-55904.
21. Nagata, K., Kawajiri, A., Matsui, S., Takagishi, M., Shiromizu, T., Saitoh, N., Izawa, I., Kiyono, T., Itoh, T.J., Hotani, H., et al. (2003). Filament formation of MSF-A, a mammalian septin, in human mammary epithelial cells depends on interactions with microtubules. J. Biol. Chem. 278, 18538-18543.
22. Russell, S.E., and Hall, P.A. (2005). Do septins have a role in cancer? Br. J. Cancer. 93, 499-503.
23. Surka, M.C., Tsang, C.W., and Trimble, W.S. (2002). The mammalian septin MSF localizes with microtubules and is required for completion of cytokinesis. Mol. Biol. Cell 13, 3532-3545.
24. Versele, M., and Thorner, J. (2004). Septin collar formation in budding yeast requires GTP binding and direct phosphorylation by the PAK, Cla4. J. Cell Biol. 164, 701-715.
25. Versele, M., and Thorner, J. (2005). Some assembly required: yeast septins provide the instruction manual. Trends Cell Biol. 15, 414-424.
26. Vrabioiu, A.M., Gerber, S.A., Gygi, S.P., Field, C.M., and Mitchison, T.J. (2004). The majority of the Saccharomyces cerevisiae septin complexes do not exchange guanine nucleotides. J. Biol. Chem. 279, 3111-3118.
27. Xue, J., Wang, X., Malladi, C.S., Kinoshita, M., Milburn, P.J., Lengyel, I., Rostas, J.A., and Robinson, P.J. (2000). Phosphorylation of a new brain-specific septin, G-septin, by cGMP-dependent protein kinase. J. Biol. Chem. 275, 10047-10056.