Impact of menthol inhalation on nasal mucosal temperature and nasal patency

American Journal of Rhinology

Volumn 22, Issue 4, 2008, Pages 402-405

  Lindemann, Joerg ^a   Tsakiropoulou, Evangelia ^b   Scheithauer, Marc O ^a   Konstantinidis, Iordanis ^b   Wiesmiller, Kerstin M ^a  

^a UNIVERSITY OF ULM   (Germany)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Cold receptors; Cooling sensation; Menthol; Nasal mucosal temperature; Nasal patency; Nasal valve; Rhinomanometry; Trigeminal; Visual analog scale

Indexed keywords

MENTHOL;

ADULT; ARTICLE; FEMALE; HUMAN; HUMAN EXPERIMENT; INHALATION; MALE; MANOMETRY; MEASUREMENT; NORMAL HUMAN; NOSE AIRFLOW; NOSE BREATHING; NOSE MUCOSA; TEMPERATURE; VAPOR; VISUAL ANALOG SCALE; VOLUNTEER;

ADMINISTRATION, INHALATION; ADULT; AIRWAY RESISTANCE; ANTIPRURITICS; BODY TEMPERATURE; FEMALE; HUMANS; MALE; MENTHOL; MIDDLE AGED; NASAL MUCOSA; RHINOMANOMETRY; SENSATION;

EID: 51049109168     PISSN: 10506586     EISSN: None     Source Type: Journal    
DOI: 10.2500/ajr.2008.22.3194     Document Type: Article

References (22)

1. Passali D, Mezzedimi C, Passali GC, et al. The role of rhinomanometry, acoustic rhinometry, and mucociliary transport time in the assessment of nasal patency. Ear Nose Throat J 79:397-400, 2000.
2. Jones AS, Wight RG, and Durham LH. The distribution of thermoreceptors within the nasal cavity. Clin Otolaryngol 14:235-239, 1989.
3. Eccles R. Menthol: Effects on nasal sensation of airflow and the drive to breath. Curr Allergy Asthma Rep 3:210-214, 2003.
4. Eccles R, Griffiths DH, Newton CG, et al. The effects of D and L isomers of menthol upon nasal sensation of airflow. J Laryngol Otol 102:506-508, 1988.
5. Lindemann J, Keck T, Leiacker R, et al. Nasal mucosal temperature in relation to nasal airflow as measured by rhinomanometry. Am J Rhinol 21:46-49, 2007.
6. Lindemann J, Keck T, Wiesmiller K, et al. Nasal air temperature and airflow during respiration in numerical simulation based on multislice computed tomography scan. Am J Rhinol 20:219-223, 2006.
7. Lindemann J, Leiacker R, Rettinger G, et al. The effect of topical xylometazoline on the mucosal temperature of the nasal septum. Am J Rhinol 16:229-234, 2002.
8. Lindemann J, Leiacker R, Rettinger G, et al. Nasal mucosal temperature during respiration. Clin Otolaryngol 27:135-139, 2002.
9. Clement PAR, and Gordts F. Consensus report on acoustic rhinometry and rhinomanometry. Rhinology 43:169-179, 2005.
10. Naito K, Komori M, Kondo Y, et al. The effect of L-menthol stimulation of the major palatine nerve on subjective and objective nasal patency. Auris Nasus Larynx 24:159-162, 1997.
11. Naito K, Ohoka E, Kato R, et al. The effect of L-menthol stimulation of the major palatine nerve on nasal patency. Auris Nasus Larynx 18:221-226, 1991.
12. Eccles R, Morris S, and Tolley NS. The effects of nasal anaesthesia upon nasal sensation of airflow. Acta Otolaryngol 106:152-155, 1988.
13. Schafer K, Braun HA, and Isenberg C. Effect of menthol on cold receptor activity. J Gen Physiol 88:757-776, 1986.
14. Eccles R, and Jones AS. The effect of menthol on nasal resistance to air flow. J Laryngol Otol 97:705-709, 1983.
15. Doty RL. In Handbook of Olfaction and Gustation. Doty RL (Ed), chap. 21. New York: Marcel Dekker, 821-833, 1995.
16. Peier AM, Moqrich A, Hergarden AC, et al. A TRP channel that senses cold stimuli and menthol. Cell 108:705-715, 2002.
17. Willatt DJ, and Jones AS. The role of the temperature of the nasal lining in the sensation of nasal patency. Clin Otolaryngol 21:519-523, 1996.
18. Frasnelli J, Heilmann S, and Hummel T. Responsiveness of human nasal mucosa to trigeminal stimuli depends on the site of stimulation. Neurosci Lett 362:65-69, 2004.
19. Jones AS, Wight RG, and Durham LH. The distribution of thermoreceptors within the nasal cavity. Clin Otolaryngol 14:235-239, 1989.
20. Sekizawa S, Tsubone H, Kuwahara M, et al. Nasal receptors responding to cold and 1-menthol airflow in the guinea pig. Respir Physiol 103:211-219, 1996.
21. Bautista DM, Siemens J, Glazer JM, et al. The menthol receptor TRPM8 is the principal detector of environmental cold. Nature 448:204-209, 2007.
22. Chu YH, Wu CC, and Wang HW. Effect of cooling on electrical field stimulation and norepinephrine-induced contraction in isolated hypertrophic human nasal mucosa. Am J Rhinol 20:471-475, 2006.