Single- and multiple-dose pharmacokinetics of genistein capsules in healthy chinese subjects: A phase I, randomized, open-label study

Current Therapeutic Research - Clinical and Experimental

Volumn 69, Issue 4, 2008, Pages 318-333

  Zeng, Xing ^a   Feng, Yi ^a   Yang, Liu ^a   Huang, Yu ^a   Zhou, Dan ^a   Sun, Jing ^a   Liu, Yiming ^a   Deng, Yuanhui ^a  

^a GUANGDONG PROVINCIAL HOSPITAL OF CHINESE MEDICINE   (China)

Author keywords

genistein capsule; healthy Chinese subject; multiple dose; pharmacokinetics; single dose

Indexed keywords

ASCORBIC ACID; ESTRADIOL; GENISTEIN; GLUCURONOLACTONE; GLUTATHIONE;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; AREA UNDER THE CURVE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CHINESE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DEMOGRAPHY; DRUG BLOOD LEVEL; DRUG CAPSULE; DRUG DOSE ESCALATION; DRUG GLUCURONIDATION; DRUG HALF LIFE; DRUG INDICATION; DRUG STRUCTURE; DRUG TOLERABILITY; ECG ABNORMALITY; ERYTHROCYTE COUNT; FEMALE; FOOD; FOOD DRUG INTERACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LEUKOCYTE COUNT; MALE; MAXIMUM PLASMA CONCENTRATION; MULTIPLE DRUG DOSE; NAUSEA; OPEN STUDY; OSTEOPOROSIS; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REPEATED DRUG DOSE; SIDE EFFECT; SINGLE DRUG DOSE; SOPHORA; TANDEM MASS SPECTROMETRY; THYROTROPIN BLOOD LEVEL; TIME TO MAXIMUM PLASMA CONCENTRATION; VOLUNTEER; VOMITING;

EID: 51049090138     PISSN: 0011393X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.curtheres.2008.08.006     Document Type: Article

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