Exposure to maternal diabetes induces salt-sensitive hypertension and impairs renal function in adult rat offspring

Diabetes

Volumn 57, Issue 8, 2008, Pages 2167-2175

  Nehiri, Touria ^a,b,c   Van Huyen, Jean Paul Duong ^a,b,c,d   Viltard, Melanie ^a,b,c   Fassot, Céline ^a,b,c   Heudes, Didier ^a,b,c,d   Freund, Nicole ^a,b,c   Deschênes, Georges ^e   Houillier, Pascal ^a,b,c,d   Bruneval, Patrick ^a,b,c,d   Lelievre Pégorier, Martine ^a,b,c  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^e HÔPITAL ROBERT DEBRÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

RENIN; SODIUM CHLORIDE; STREPTOZOCIN; EPITHELIAL SODIUM CHANNEL;

ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GESTATIONAL AGE; GLOMERULUS; HISTOPATHOLOGY; HYPERTENSION; KIDNEY FUNCTION; KIDNEY PARENCHYMA; MALE; MATERNAL DIABETES MELLITUS; MORPHOMETRICS; NEWBORN; NONHUMAN; PLASMA RENIN ACTIVITY; PREGNANCY; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROGENY; RAT; SALT INTAKE; SODIUM TRANSPORT; SPRAGUE DAWLEY RAT; SYSTOLIC BLOOD PRESSURE; WESTERN BLOTTING; ANIMAL; BLOOD PRESSURE; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; GLOMERULUS FILTRATION RATE; IMMUNOHISTOCHEMISTRY; KIDNEY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PREGNANCY DIABETES MELLITUS; TIME;

ANIMALS; ANIMALS, NEWBORN; BLOOD PRESSURE; BLOTTING, WESTERN; DIABETES MELLITUS, EXPERIMENTAL; EPITHELIAL SODIUM CHANNEL; FEMALE; GLOMERULAR FILTRATION RATE; HYPERTENSION; IMMUNOHISTOCHEMISTRY; KIDNEY; PREGNANCY; PREGNANCY IN DIABETICS; RATS; RATS, SPRAGUE-DAWLEY; RENIN; SODIUM CHLORIDE, DIETARY; TIME FACTORS;

EID: 50949134253     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db07-0780     Document Type: Article

References (33)

1. National Center for Health Statistics: Pregnancy complications and outcomes among women with diabetes-North Carolina. MMWR Morb Mortal Wkly Rep 42:847-851, 1993
2. National Center for Health Statistics: Prenatal care and pregnancies complicated by diabetes: U.S. reporting areas. MMWR Morb Mortal Wkly Rep 42:119-122, 1993
3. Jensen DM, Damm P, Moelsted-Pedersen L, Ovesen P, Westergaard JG, Moeller M, Beck-Nielsen H: Outcomes in type 1 diabetic pregnancies: a nationwide, population-based study. Diabetes Care 27:2819-2823, 2004
4. Casson IF, Clarke CA, Howard CV, McKendrick O, Pennycook S, Pharoah PO, Platt MJ, Stanisstreet M, van Velszen D, Walkinshaw S: Outcomes of pregnancy in insulin dependent diabetic women: results of a five year population cohort study. BMJ 315:275-278, 1997
5. Fuhrmann K, Reiher H, Semmler K, Fischer F, Fischer M, Glockner E: Prevention of congenital malformations in infants of insulin-dependent diabetic mothers. Diabetes Care 6:219-223, 1983
6. Lynch SA, Wright C: Sirenomelia, limb reduction defects, cardiovascular malformation, renal agenesis in an infant born to a diabetic mother. Clin Dysmorphol 6:75-80, 1997
7. Fetita LS, Sobngwi E, Serradas P, Calvo F, Gautier JF: Consequences of fetal exposure to maternal diabetes in offspring. J Clin Endocrinol Metab 91:3718-3724, 2006
8. Rocha SO, Gomes GN, Forti AL, do Carmo Pinho Franco M, Fortes ZB, de Fatima Cavanal M, Gil FZ: Long-term effects of maternal diabetes on vascular reactivity and renal function in rat male offspring. Pediatr Res 58:1274-1279, 2005
9. Magaton A, Gil FZ, Casarini DE, Cavanal MD, Gomes GN: Maternal diabetes mellitus: early consequences for the offspring. Pediatr Nephrol 22:37-43, 2007
10. Barker DJ, Bagby SP: Developmental antecedents of cardiovascular disease: a historical perspective. J Am Soc Nephrol 16:2537-2544, 2005
11. McMillen IC, Robinson JS: Developmental origins of the metabolic syndrome: prediction, plasticity, and programming. Physiol Rev 85:571-633, 2005
12. Zandi-Nejad K, Luyckx VA, Brenner BM: Adult hypertension and kidney disease: the role of fetal programming. Hypertension 47:502-508, 2006
13. Amri K, Freund N, Vilar J, Merlet-Benichou C, Lelievre-Pegorier M: Adverse effects of hyperglycemia on kidney development in rats: in vivo and in vitro studies. Diabetes 48:2240-2245, 1999
14. Amri K, Freund N, Van Huyen JP, Merlet-Benichou C, Lelievre-Pegorier M: Altered nephrogenesis due to maternal diabetes is associated with increased expression of IGF-II/mannose-6-phosphate receptor in the fetal kidney. Diabetes 50:1069-1075, 2001
15. Duong Van Huyen JP, Amri K, Belair MF, Vilar J, Merlet-Benichou C, Bruneval P, Lelievre-Pegorier M: Spatiotemporal distribution ofinsulin-like growth factor receptors during nephrogenesis in fetuses from normal and diabetic rats. Cell Tissue Res 314:367-379, 2003
16. Karam H, Clozel JP, Bruneval P, Gonzalez MF, Menard J: Contrasting effects of selective T- and L-type calcium channel blockade on glomerular damage in DOCA hypertensive rats. Hypertension 34:673-678, 1999
17. Francois V, Heudes D, Bariety J, Bruneval P, Corman B: Glomerular capillary network of cortical nephrons is reduced in male but not in female aging rats. Mech Ageing Dev 91:11-22, 1996
18. Heudes D, Michel O, Chevalier J, Scalbert E, Ezan E, Bariety J, Zimmerman A, Corman B: Effect of chronic ANG I-converting enzyme inhibition on aging processes: I. Kidney structure and function. Am J Physiol 266: R1038-R1051, 1994
19. Pietri L, Bloch-Faure M, Belair MF, Sanford LP, Doetschman T, Menard J, Bruneval P, Meneton P: Altered renin synthesis and secretion in the kidneys of heterozygous mice with a null mutation in the TGF-beta(2) gene. Exp Nephrol 10:374-382, 2002
20. Quentin F, Eladari D, Frische S, Cambillau M, Nielsen S, Alper SL, Paillard M, Chambrey R: Regulation of the Cl-/HCO3- exchanger AE2 in rat thick ascending limb of Henle's loop in response to changes in acid-base and sodium balance. J Am Soc Nephrol 15:2988-2997, 2004
21. Lourdel S, Lofflng J, Favre G, Paulais M, Nissant A, Fakitsas P, Creminon C, Feraille E, Verrey F, Teulon J, Doucet A, Deschenes G: Hyperaldoste- ronemia and activation of the epithelial sodium channel are not required for sodium retention in puromycin-induced nephrosis. J Am Soc Nephrol 16:3642-3650, 2005
22. Woods LL, Weeks DA, Rasch R: Hypertension after neonatal unine- phrectomy in rats precedes glomerular damage. Hypertension 38:337342, 2001
23. Brenner BM, Garcia DL, Anderson S: Glomeruli and blood pressure: less of one, more the other? Am J Hypertens 1:335-347, 1988
24. Skov K, Nyengaard JR, Korsgaard N, Mulvany MJ: Number and size ofrenal glomeruli in spontaneously hypertensive rats. J Hypertens 12:1373-1376, 1994
25. Fassi A, Sangalli F, Maffi R, Colombi F, Mohamed EI, Brenner BM, Remuzzi G, Remuzzi A: Progressive glomerular injury in the MWF rat is predicted by inborn nephron deficit. J Am Soc Nephrol 9:1399-1406, 1998
26. Black MJ, Briscoe TA, Constantinou M, Kett MM, Bertram JF: Is there an association between level of adult blood pressure and nephron number or renal filtration surface area? Kidney Int 65:582-588, 2004
27. Meneton P, Jeunemaitre X, de Wardener HE, MacGregor GA: Links between dietary salt intake, renal salt handling, blood pressure, and cardiovascular diseases. Physiol Rev 85:679-715, 2005
28. Manning J, Beutler K, Knepper MA, Vehaskari VM: Upregulation of renal BSC1 and TSC in prenatally programmed hypertension. Am J Physiol Renal Physiol 283:F202-F206, 2002
29. Kim SW, Wang W, Kwon TH, Knepper MA, Frokiaer J, Nielsen S: Increased expression of ENaC subunits and increased apical targeting of AQP2 in the kidneys of spontaneously hypertensive rats. Am J Physiol Renal Physiol 289:F957-F968, 2005
30. Gilbert T, Lelievre-Pegorier M, Merlet-Benichou C: Immediate and long- term renal effects of fetal exposure to gentamicin. Pediatr Nephrol 4:445-450, 1990
31. Tendron-Franzin A, Gouyon JB, Guignard JP, Decramer S, Justrabo E, Gilbert T, Semama DS: Long-term effects of in utero exposure to cyclo- sporin A on renal function in the rabbit. J Am Soc Nephrol 15:2687-2693, 2004
32. Doggrell SA, Brown L: Rat models of hypertension, cardiac hypertrophy and failure. Cardiovasc Res 39:89-105, 1998
33. Vehaskari VM, Woods LL: Prenatal programming of hypertension: lessons from experimental models. J Am Soc Nephrol 16:2545-2556, 2005