-
1
-
-
34547629612
-
Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic Clostridium difficile strains in the cecal contents of mice
-
Adams, D. A., M. M. Riggs, and C. J. Donskey. 2007. Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic Clostridium difficile strains in the cecal contents of mice. Antimicrob. Agents Chemother. 51:2674-2678.
-
(2007)
Antimicrob. Agents Chemother
, vol.51
, pp. 2674-2678
-
-
Adams, D.A.1
Riggs, M.M.2
Donskey, C.J.3
-
2
-
-
33646441418
-
Antimicrobial susceptibility pattern of Clostridium difficile and its relation to PCR ribotypes in a Swedish university hospital
-
Aspevall, O., A. Lundberg, L. G. Burman, T. Akerlund, and B. Svenungsson. 2006. Antimicrobial susceptibility pattern of Clostridium difficile and its relation to PCR ribotypes in a Swedish university hospital. Antimicrob. Agents Chemother. 50:1890-1892.
-
(2006)
Antimicrob. Agents Chemother
, vol.50
, pp. 1890-1892
-
-
Aspevall, O.1
Lundberg, A.2
Burman, L.G.3
Akerlund, T.4
Svenungsson, B.5
-
3
-
-
35048865459
-
Prospective study of Clostridium difficile infections in Europe with phenotypic and genotypic characterisation of the isolates
-
Barbut, F., P. Mastrantonio, M. Delmee, J. Brazier, E. Kuijper, and I. Poxton. 2007. Prospective study of Clostridium difficile infections in Europe with phenotypic and genotypic characterisation of the isolates. Clin. Microbiol. Infect. 13:1048-1057.
-
(2007)
Clin. Microbiol. Infect
, vol.13
, pp. 1048-1057
-
-
Barbut, F.1
Mastrantonio, P.2
Delmee, M.3
Brazier, J.4
Kuijper, E.5
Poxton, I.6
-
4
-
-
0022491104
-
Faecal metronidazole concentrations during oral and intravenous therapy for antibiotic associated colitis due to Clostridium difficile
-
Bolton, R. P., and M. A. Culshaw. 1986. Faecal metronidazole concentrations during oral and intravenous therapy for antibiotic associated colitis due to Clostridium difficile. Gut 27:1169-1172.
-
(1986)
Gut
, vol.27
, pp. 1169-1172
-
-
Bolton, R.P.1
Culshaw, M.A.2
-
5
-
-
0027940266
-
Validation of a combined comorbidity index
-
Charlson, M., T. P. Szatrowski, J. Peterson, and J. Gold. 1994. Validation of a combined comorbidity index. J. Clin. Epidemiol. 47:1245-1251.
-
(1994)
J. Clin. Epidemiol
, vol.47
, pp. 1245-1251
-
-
Charlson, M.1
Szatrowski, T.P.2
Peterson, J.3
Gold, J.4
-
6
-
-
50949095671
-
-
Comité sur les Infections Nosocomiales du Québec. 2005. Prévention et contrôle de la diarrhée nosocomiale associée au Clostridium difficile au Québec - lignes directrices pour les établissements de soins, 3e éd., février 2005. http://www.inspq.qc.ca/pdf/publications/362-CDifficile- LignesDirectrices -3eEdition.pdf. Accessed 30 April 2007.
-
Comité sur les Infections Nosocomiales du Québec. 2005. Prévention et contrôle de la diarrhée nosocomiale associée au Clostridium difficile au Québec - lignes directrices pour les établissements de soins, 3e éd., février 2005. http://www.inspq.qc.ca/pdf/publications/362-CDifficile- LignesDirectrices -3eEdition.pdf. Accessed 30 April 2007.
-
-
-
-
7
-
-
34249712006
-
Evaluation of Clostridium difficile-associated disease pressure as a risk factor for C. difficile-associated disease
-
Dubberke, E. R., K. A. Reske, M. A. Olsen, K. M. McMullen, J. L. Mayfield, L. C. McDonald, and V. J. Fraser. 2007. Evaluation of Clostridium difficile-associated disease pressure as a risk factor for C. difficile-associated disease. Arch. Intern. Med. 167:1092-1097.
-
(2007)
Arch. Intern. Med
, vol.167
, pp. 1092-1097
-
-
Dubberke, E.R.1
Reske, K.A.2
Olsen, M.A.3
McMullen, K.M.4
Mayfield, J.L.5
McDonald, L.C.6
Fraser, V.J.7
-
8
-
-
40449114824
-
Clostridium difficile-associated disease in a setting of endemicity: Identification of novel risk factors
-
Dubberke, E. R., K. A. Reske, Y. Yan, M. A. Olsen, L. C. McDonald, and V. J. Fraser. 2007. Clostridium difficile-associated disease in a setting of endemicity: identification of novel risk factors. Clin. Infect. Dis. 45:1543-1549.
-
(2007)
Clin. Infect. Dis
, vol.45
, pp. 1543-1549
-
-
Dubberke, E.R.1
Reske, K.A.2
Yan, Y.3
Olsen, M.A.4
McDonald, L.C.5
Fraser, V.J.6
-
9
-
-
34548487752
-
Spread and epidemiology of Clostridium difficile polymerase chain reaction ribotype 027/toxinotype III in The Netherlands
-
Goorhuis, A., T. van der Kooi, N. Vaessen, F. W. Dekker, R. Van den Berg, C. Harmanus, S. van den Hof, D. W. Notermans, and E. J. Kuijper. 2007. Spread and epidemiology of Clostridium difficile polymerase chain reaction ribotype 027/toxinotype III in The Netherlands. Clin. Infect. Dis. 45:695-703.
-
(2007)
Clin. Infect. Dis
, vol.45
, pp. 695-703
-
-
Goorhuis, A.1
van der Kooi, T.2
Vaessen, N.3
Dekker, F.W.4
Van den Berg, R.5
Harmanus, C.6
van den Hof, S.7
Notermans, D.W.8
Kuijper, E.J.9
-
10
-
-
0036263387
-
Development and evaluation of a PCR method for detection of the Clostridium difficile toxin B gene in stool specimens
-
Guilbault, C., A. C. Labbe, L. Poirier, L. Busque, C. Beliveau, and M. Laverdiere. 2002. Development and evaluation of a PCR method for detection of the Clostridium difficile toxin B gene in stool specimens. J. Clin. Microbiol. 40:2288-2290.
-
(2002)
J. Clin. Microbiol
, vol.40
, pp. 2288-2290
-
-
Guilbault, C.1
Labbe, A.C.2
Poirier, L.3
Busque, L.4
Beliveau, C.5
Laverdiere, M.6
-
11
-
-
50949101393
-
-
Mandatory surveillance of healthcare associated infections report, Accessed 25 November 2006
-
Health Protection Agency. 2006. Mandatory surveillance of healthcare associated infections report, 2006. http://www.hpa.org.uk/infections/ topics_az/hai/mandatory_report_2006.htm. Accessed 25 November 2006.
-
(2006)
Health Protection Agency. 2006
-
-
-
12
-
-
33846156548
-
A portrait of the geographic dissemination of the Clostridium difficile North American pulsed-field type 1 strain and the epidemiology of C. difficile-associated disease in Quebec
-
Hubert, B., V. G. Loo, A. M. Bourgault, L. Poirier, A. Daseal, E. Fortin, M. Dionne, and M. Lorange. 2007. A portrait of the geographic dissemination of the Clostridium difficile North American pulsed-field type 1 strain and the epidemiology of C. difficile-associated disease in Quebec. Clin. Infect. Dis. 44:238-244.
-
(2007)
Clin. Infect. Dis
, vol.44
, pp. 238-244
-
-
Hubert, B.1
Loo, V.G.2
Bourgault, A.M.3
Poirier, L.4
Daseal, A.5
Fortin, E.6
Dionne, M.7
Lorange, M.8
-
14
-
-
50949124397
-
La situation démographique au Québec
-
Institut National de Santé Publique du Québec, //. Accessed 15 December 2007
-
Institut National de Santé Publique du Québec. 2006. La situation démographique au Québec. Bilan 2006. Institut de Statistique du Québec, http: //www.stat.gouv.qc.ca/publications/demograp/ pdf2006/Bilan2006c4.pdf. Accessed 15 December 2007.
-
(2006)
Bilan 2006. Institut de Statistique du Québec, http
-
-
-
15
-
-
33646567932
-
-
Joseph, R., D. Demeyer, D. Vanrenterghem, R. van den Berg, E. Kuijper, and M. Delmee. 2005. First isolation of Clostridium difficile PCR ribotype 027, toxinotype III in Belgium. Euro. Surveill. 10:E051020.
-
Joseph, R., D. Demeyer, D. Vanrenterghem, R. van den Berg, E. Kuijper, and M. Delmee. 2005. First isolation of Clostridium difficile PCR ribotype 027, toxinotype III in Belgium. Euro. Surveill. 10:E051020.
-
-
-
-
16
-
-
37349036379
-
Update of Clostridium difficile-associated disease due to PCR ribotype 027 in Europe
-
Kuijper, E. J., B. Coignard, J. S. Brazier, C. Suetens, D. Drudy, C. Wiuff, H. Pituch, P. Reichert, F. Schneider, A. F. Widmer, K. E. Olsen, F. Allerberger, D. W. Notermans, F. Barbut, M. Delmee, M. Wilcox, A. Pearson, B. C. Patel, D. J. Brown, R. Frei, T. Akerlund, I. R. Poxton, and P. Tull. 2007. Update of Clostridium difficile-associated disease due to PCR ribotype 027 in Europe. Euro. Surveill. 12:E1-E2.
-
(2007)
Euro. Surveill
, vol.12
-
-
Kuijper, E.J.1
Coignard, B.2
Brazier, J.S.3
Suetens, C.4
Drudy, D.5
Wiuff, C.6
Pituch, H.7
Reichert, P.8
Schneider, F.9
Widmer, A.F.10
Olsen, K.E.11
Allerberger, F.12
Notermans, D.W.13
Barbut, F.14
Delmee, M.15
Wilcox, M.16
Pearson, A.17
Patel, B.C.18
Brown, D.J.19
Frei, R.20
Akerlund, T.21
Poxton, I.R.22
Tull, P.23
more..
-
17
-
-
33646562852
-
Clostridium difficile ribotype 027, toxinotype III, The Netherlands
-
Kuijper, E. J., R. J. van den Berg, S. Debast, C. E. Visser, D. Veenendaal, A. Troelstra, T. van der Kooi, S. van den Hof, and D. W. Notermans. 2006. Clostridium difficile ribotype 027, toxinotype III, The Netherlands. Emerg. Infect. Dis. 12:827-830.
-
(2006)
Emerg. Infect. Dis
, vol.12
, pp. 827-830
-
-
Kuijper, E.J.1
van den Berg, R.J.2
Debast, S.3
Visser, C.E.4
Veenendaal, D.5
Troelstra, A.6
van der Kooi, T.7
van den Hof, S.8
Notermans, D.W.9
-
18
-
-
28844441314
-
A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality
-
Loo, V. G., L. Poirier, M. A. Miller, M. Oughton, M. D. Libman, S. Michaud, A. M. Bourgault, T. Nguyen, C. Frenette, M. Kelly, A. Vibien, P. Brassard, S. Fenn, K. Dewar, T. J. Hudson, R. Horn, P. Rene, Y. Monczak, and A. Daseal. 2005. A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality. N. Engl. J. Med. 353:2442-2449.
-
(2005)
N. Engl. J. Med
, vol.353
, pp. 2442-2449
-
-
Loo, V.G.1
Poirier, L.2
Miller, M.A.3
Oughton, M.4
Libman, M.D.5
Michaud, S.6
Bourgault, A.M.7
Nguyen, T.8
Frenette, C.9
Kelly, M.10
Vibien, A.11
Brassard, P.12
Fenn, S.13
Dewar, K.14
Hudson, T.J.15
Horn, R.16
Rene, P.17
Monczak, Y.18
Daseal, A.19
-
19
-
-
33745120517
-
Molecular analysis of Clostridium difficile PCR ribotype 027 isolates from eastern and western Canada
-
MacCannell, D. R., T. J. Louie, D. B. Gregson, M. Laverdiere, A. C. Labbe, F. Laing, and S. Henwick. 2006. Molecular analysis of Clostridium difficile PCR ribotype 027 isolates from eastern and western Canada. J. Clin. Microbiol. 44:2147-2152.
-
(2006)
J. Clin. Microbiol
, vol.44
, pp. 2147-2152
-
-
MacCannell, D.R.1
Louie, T.J.2
Gregson, D.B.3
Laverdiere, M.4
Labbe, A.C.5
Laing, F.6
Henwick, S.7
-
20
-
-
34249782307
-
Clostridium difficile toxin expression is inhibited by the novel regulator TcdC
-
Matamouros, S., P. England, and B. Dupuy. 2007. Clostridium difficile toxin expression is inhibited by the novel regulator TcdC. Mol. Microbiol. 64: 1274-1288.
-
(2007)
Mol. Microbiol
, vol.64
, pp. 1274-1288
-
-
Matamouros, S.1
England, P.2
Dupuy, B.3
-
21
-
-
36049015601
-
Confronting Clostridium difficile in inpatient health care facilities
-
McDonald, L. C. 2007. Confronting Clostridium difficile in inpatient health care facilities. Clin. Infect. Dis. 45:1274-1276.
-
(2007)
Clin. Infect. Dis
, vol.45
, pp. 1274-1276
-
-
McDonald, L.C.1
-
22
-
-
28844494086
-
An epidemic, toxin gene-variant strain of Clostridium difficile
-
McDonald, L. C, G. E. Killgore, A. Thompson, R. C. Owens, Jr., S. V. Kazakova, S. P. Sambol, S. Johnson, and D. N. Gerding. 2005. An epidemic, toxin gene-variant strain of Clostridium difficile. N. Engl. J. Med. 353:2433-2441.
-
(2005)
N. Engl. J. Med
, vol.353
, pp. 2433-2441
-
-
McDonald, L.C.1
Killgore, G.E.2
Thompson, A.3
Owens Jr., R.C.4
Kazakova, S.V.5
Sambol, S.P.6
Johnson, S.7
Gerding, D.N.8
-
23
-
-
33644523410
-
Clostridium difficile infection in patients discharged from US short-stay hospitals, 1996-2003
-
McDonald, L. C., M. Owings, and D. B. Jernigan. 2006. Clostridium difficile infection in patients discharged from US short-stay hospitals, 1996-2003. Emerg. Infect. Dis. 12:409-415.
-
(2006)
Emerg. Infect. Dis
, vol.12
, pp. 409-415
-
-
McDonald, L.C.1
Owings, M.2
Jernigan, D.B.3
-
24
-
-
33746626011
-
Nitazoxanide for the treatment of Clostridium difficile colitis
-
Musher, D. M., N. Logan, R. J. Hamill, H. L. Dupont, A. Lentnek, A. Gupta, and J. F. Rossignol. 2006. Nitazoxanide for the treatment of Clostridium difficile colitis. Clin. Infect. Dis. 43:421-427.
-
(2006)
Clin. Infect. Dis
, vol.43
, pp. 421-427
-
-
Musher, D.M.1
Logan, N.2
Hamill, R.J.3
Dupont, H.L.4
Lentnek, A.5
Gupta, A.6
Rossignol, J.F.7
-
25
-
-
36048999595
-
Control of an outbreak of infection with the hypervirulent Clostridium difficile BI strain in a university hospital using a comprehensive "bundle" approach
-
Muto, C. A., M. K. Blank, J. W. Marsh, E. N. Vergis, M. M. O'Leary, K. A. Shutt, A. W. Pasculle, M. Pokrywka, J. G. Garcia, K. Posey, T. L. Roberts, B. A. Potoski, G. E. Blank, R. L. Simmons, P. Veldkamp, L. H. Harrison, and D. L. Paterson. 2007. Control of an outbreak of infection with the hypervirulent Clostridium difficile BI strain in a university hospital using a comprehensive "bundle" approach. Clin. Infect. Dis. 45:1266-1273.
-
(2007)
Clin. Infect. Dis
, vol.45
, pp. 1266-1273
-
-
Muto, C.A.1
Blank, M.K.2
Marsh, J.W.3
Vergis, E.N.4
O'Leary, M.M.5
Shutt, K.A.6
Pasculle, A.W.7
Pokrywka, M.8
Garcia, J.G.9
Posey, K.10
Roberts, T.L.11
Potoski, B.A.12
Blank, G.E.13
Simmons, R.L.14
Veldkamp, P.15
Harrison, L.H.16
Paterson, D.L.17
-
26
-
-
20144386999
-
A large outbreak of Clostridium difficile-associated disease with an unexpected proportion of deaths and colectomies at a teaching hospital following increased fluoroquinolone use
-
Muto, C. A., M. Pokrywka, K. Shutt, A. B. Mendelsohn, K. Nouri, K. Posey, T. Roberts, K. Croyle, S. Krystofiak, S. Patel-Brown, A. W. Pasculle, D. L. Paterson, M. Saul, and L. H. Harrison. 2005. A large outbreak of Clostridium difficile-associated disease with an unexpected proportion of deaths and colectomies at a teaching hospital following increased fluoroquinolone use. Infect. Control Hosp. Epidemiol. 26:273-280.
-
(2005)
Infect. Control Hosp. Epidemiol
, vol.26
, pp. 273-280
-
-
Muto, C.A.1
Pokrywka, M.2
Shutt, K.3
Mendelsohn, A.B.4
Nouri, K.5
Posey, K.6
Roberts, T.7
Croyle, K.8
Krystofiak, S.9
Patel-Brown, S.10
Pasculle, A.W.11
Paterson, D.L.12
Saul, M.13
Harrison, L.H.14
-
27
-
-
3042797680
-
Methods for antimicrobial susceptibility testing of anaerobic bacteria; approved standard
-
National Committee for Clinical Laboratory Standards, 6th ed, National Committee for Clinical Laboratory Standards, Wayne, PA
-
National Committee for Clinical Laboratory Standards. 2004. Methods for antimicrobial susceptibility testing of anaerobic bacteria; approved standard, 6th ed. NCCLS document M11-A6, Vol. 24, No. 2. National Committee for Clinical Laboratory Standards, Wayne, PA.
-
(2004)
NCCLS document
, vol.24
, Issue.2
-
-
-
28
-
-
39749120072
-
Antimicrobial-associated risk factors for Clostridium difficile infection
-
Owens, R. C., Jr., C. J. Donskey, R. Gaynes, V. G. Loo, and C. A. Muto. 2008. Antimicrobial-associated risk factors for Clostridium difficile infection. Clin. Infect. Dis. 46(Suppl. 1):S19-S31.
-
(2008)
Clin. Infect. Dis
, vol.46
, Issue.SUPPL. 1
-
-
Owens Jr., R.C.1
Donskey, C.J.2
Gaynes, R.3
Loo, V.G.4
Muto, C.A.5
-
29
-
-
27444437759
-
Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficile-associated diarrhea: A cohort study during an epidemic in Quebec
-
Pepin, J., N. Saheb, M. A. Coulombe, M. E. Alary, M. P. Corriveau, S. Authier, M. Leblanc, G. Rivard, M. Bettez, V. Primeau, M. Nguyen, C. E. Jacob, and L. Lanthier. 2005. Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficile-associated diarrhea: a cohort study during an epidemic in Quebec. Clin. Infect. Dis. 41:1254-1260.
-
(2005)
Clin. Infect. Dis
, vol.41
, pp. 1254-1260
-
-
Pepin, J.1
Saheb, N.2
Coulombe, M.A.3
Alary, M.E.4
Corriveau, M.P.5
Authier, S.6
Leblanc, M.7
Rivard, G.8
Bettez, M.9
Primeau, V.10
Nguyen, M.11
Jacob, C.E.12
Lanthier, L.13
-
30
-
-
27544511378
-
Mortality attributable to nosocomial Clostridium difficile-associated disease during an epidemic caused by a hypervirulent strain in Quebec
-
Pepin, J., L. Valiquette, and B. Cossette. 2005. Mortality attributable to nosocomial Clostridium difficile-associated disease during an epidemic caused by a hypervirulent strain in Quebec. CMAJ 173:1037-1042.
-
(2005)
CMAJ
, vol.173
, pp. 1037-1042
-
-
Pepin, J.1
Valiquette, L.2
Cossette, B.3
-
31
-
-
34848889558
-
Clostridium difficile: Emergence of hypervirulence and fluoroquinolone resistance
-
Razavi, B., A. Apisarnthanarak, and L. M. Mundy. 2007. Clostridium difficile: emergence of hypervirulence and fluoroquinolone resistance. Infection 35:300-307.
-
(2007)
Infection
, vol.35
, pp. 300-307
-
-
Razavi, B.1
Apisarnthanarak, A.2
Mundy, L.M.3
-
32
-
-
34848836638
-
Increase in Clostridium difficile-related mortality, United States, 1999-2004
-
Redelings, M. D., F. Sorvillo, and L. Mascola. 2007. Increase in Clostridium difficile-related mortality, United States, 1999-2004. Emerg. Infect. Dis. 13:1417-1419.
-
(2007)
Emerg. Infect. Dis
, vol.13
, pp. 1417-1419
-
-
Redelings, M.D.1
Sorvillo, F.2
Mascola, L.3
-
33
-
-
34447542645
-
Increasing prevalence and severity of Clostridium difficile colitis in hospitalized patients in the United States
-
Ricciardi, R., D. A. Rothenberger, R. D. Madoff, and N. N. Baxter. 2007. Increasing prevalence and severity of Clostridium difficile colitis in hospitalized patients in the United States. Arch. Surg. 142:624-631.
-
(2007)
Arch. Surg
, vol.142
, pp. 624-631
-
-
Ricciardi, R.1
Rothenberger, D.A.2
Madoff, R.D.3
Baxter, N.N.4
-
34
-
-
33746601156
-
-
Smith, A. 2005. Outbreak of Clostridium difficile infection in an English hospital linked to hypertoxin-producing strains in Canada and the US. Euro. Surveill. 10:E050630.
-
Smith, A. 2005. Outbreak of Clostridium difficile infection in an English hospital linked to hypertoxin-producing strains in Canada and the US. Euro. Surveill. 10:E050630.
-
-
-
-
35
-
-
34548267536
-
Impact of a reduction in the use of high-risk antibiotics on the course of an epidemic of Clostridium difficile-associated disease caused by the hypervirulent NAP1/027 strain
-
Valiquette, L., B. Cossette, M. P. Garant, H. Diab, and J. Pepin. 2007. Impact of a reduction in the use of high-risk antibiotics on the course of an epidemic of Clostridium difficile-associated disease caused by the hypervirulent NAP1/027 strain. Clin. Infect. Dis. 45(Suppl. 2):S112-S121.
-
(2007)
Clin. Infect. Dis
, vol.45
, Issue.SUPPL. 2
-
-
Valiquette, L.1
Cossette, B.2
Garant, M.P.3
Diab, H.4
Pepin, J.5
-
36
-
-
25144469664
-
Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe
-
Warny, M., J. Pepin, A. Fang, G. Killgore, A. Thompson, J. Brazier, E. Frost, and L. C. McDonald. 2005. Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe. Lancet 366:1079-1084.
-
(2005)
Lancet
, vol.366
, pp. 1079-1084
-
-
Warny, M.1
Pepin, J.2
Fang, A.3
Killgore, G.4
Thompson, A.5
Brazier, J.6
Frost, E.7
McDonald, L.C.8
-
37
-
-
50849099766
-
-
WHO Collaborating Centre for Drug Statistics Methodology, Accessed 23 April 2007
-
WHO Collaborating Centre for Drug Statistics Methodology. 2007. ATC/DDD index 2007. WHO Collaborating Centre for Drug Statistics Methodology. http://www.whocc.no/atcddd/. Accessed 23 April 2007.
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(2007)
ATC/DDD index 2007
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