In vitro and in vivo trypanocidal effect of lipophilic extracts of medicinal plants from Mali and Burkina Faso

Journal of Ethnopharmacology

Volumn 119, Issue 2, 2008, Pages 225-231

  Aderbauer, Birgit ^a   Clausen, Peter Henning ^a   Kershaw, Olivia ^a   Melzig, Matthias F ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Acacia nilotica; Antitrypanosomal activity; Immunosuppressive activity; Medicinal plants; Securidaca longepedunculata; Trypanosoma brucei brucei

Indexed keywords

ACACIA NILOTICA EXTRACT; ANNONA SENEGALENSIS EXTRACT; BALANITES AEGYPTIACA EXTRACT; DICHLOROMETHANE; DIMINAZENE ACETURATE; GUIERA SENEGALENSIS EXTRACT; PLANT EXTRACT; SECURIDACA LONGEPEDUNCULATA EXTRACT; UNCLASSIFIED DRUG;

ACACIA; ACUTE KIDNEY FAILURE; AFRICAN MEDICINE; AFRICAN TRYPANOSOMIASIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANNONA SENEGALENSIS; ARTICLE; BALANITES; BARK; BURKINA FASO; CAUSE OF DEATH; CONTROLLED STUDY; DOSE CALCULATION; DRUG CYTOTOXICITY; EMBRYO; ETHNOBOTANY; EXPERIMENTAL INFECTION; FEMALE; GUIERA SENEGALENSIS; IMMUNE SYSTEM; IN VITRO STUDY; IN VIVO STUDY; MALE; MALI; MAMMAL CELL; MEDICINAL PLANT; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; PARASITEMIA; PLANT LEAF; PLANT ROOT; PLANT STEM; SECURIDACA LONGEPEDUNCULATA; TRADITIONAL MEDICINE; TRYPANOSOMA BRUCEI; TRYPANOSOMIASIS;

ANIMALS; BURKINA FASO; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MALE; MALI; MEDICINE, AFRICAN TRADITIONAL; MICROBIAL SENSITIVITY TESTS; MURINAE; PLANT EXTRACTS; PLANTS, MEDICINAL; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS, AFRICAN;

ACACIA NILOTICA; COMBRETACEAE; FABACEAE; GUIERA SENEGALENSIS; MUS; POLYGALACEAE; SECURIDACA LONGEPEDUNCULATA; TRYPANOSOMA BRUCEI BRUCEI;

EID: 50949111132     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2008.06.024     Document Type: Article

References (38)

1. Adewunmi C.O., Agbedahunsi J.M., Adebajo A.C., Aladesanmi A.J., Murphy N., and Wando J. Ethno-veterinary medicine: screening of Nigerian medicinal plants for trypanocidal properties. Journal of Ethnopharmacology 77 (2001) 19-24
2. Agunu A., Yusuf S., Andrew G.O., Zezi A.U., and Abdurahman E.M. Evaluation of five medicinal plants used in diarrhoea treatment in Nigeria. Journal of Ethnopharmacology 101 (2005) 27-30
3. Alakurtti S., Makela T., Koskimies S., and Yli-Kauhaluoma J. Pharmacological properties of the ubiquitous natural product betulin. European Journal of Pharmaceutical Sciences 29 (2006) 1-13
4. Asuzu I.U., and Chimene C.N. Effects of Morinda lucida leaf extract on Trypanosoma brucei brucei infection in mice. Journal of Ethnopharmacology 30 (1990) 307-313
5. Ayoub S.M. Polyphenolic molluscicides from Acacia nilotica. Planta Medica 50 (1984) 532
6. Baltz T., Baltz D., Giroud C., and Crockett J. Cultivation in a semi-defined medium of animal infective forms of Trypanosoma brucei, T. equiperdum, T. evansi, T. rhodesiense and T. gambiense. The EMBO Journal 4 (1985) 1273-1277
7. Bizimana N., Tietjen U., Zessin K.H., Diallo D., Djibril C., Melzig M.F., and Clausen P.-H. Evaluation of medicinal plants from Mali for their in vitro and in vivo trypanocidal activity. Journal of Ethnopharmacology 103 (2006) 350-356
8. Bouic P.J., Clark A., Lamprecht J., Freestone M., Pool E.J., Liebenberg R.W., Kotze D., and van Jaarsveld P.P. The effects of B-sitosterol (BSS) and B-sitosterol glucoside (BSSG) mixture on selected immune parameters of marathon runners: inhibition of post marathon immune suppression and inflammation. International Journal of Sports Medicine 20 (1999) 258-262
9. Bouic P.J., and Lamprecht J.H. Plant sterols and sterolins: a review of their immune-modulating properties. Alternative Medicine Review 4 (1999) 170-177
10. Brun R., Jenni L., Tanner M., Schonenberger M., and Schell K.F. Cultivation of vertebrate infective forms derived from metacyclic forms of pleomorphic Trypanosoma brucei stocks. Short communication. Acta Tropica 36 (1979) 387-390
11. Chaubal R., Mujumdar A.M., Puranik V.G., Deshpande V.H., and Deshpande N.R. Isolation and X-ray study of an anti-inflammatory active androstene steroid from Acacia nilotica. Planta Medica 69 (2003) 287-288
12. Chaubal R., Pawar P.V., Hebbalkar G.D., Tungikar V.B., Puranik V.G., Deshpande V.H., and Deshpande N.R. Larvicidal activity of Acacia nilotica extracts and isolation of d-pinitol-a bioactive carbohydrate. Chemistry and Biodiversity 2 (2005) 684-688
13. Eisler M.C., Brandt J., Bauer B., Clausen P.-H., Delespaux V., Holmes P.H., Ilemobade A., Machila N., Mbwambo H., McDermott J., Mehlitz D., Murilla G., Ndung'u J.M., Peregrine A.S., Sidibe I., Sinyangwe L., and Geerts S. Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle. Veterinary Parasitology 97 (2001) 171-182
14. Freiburghaus F., Jonker S.A., Nkunya M.H., Mwasumbi L.B., and Brun R. In vitro trypanocidal activity of some rare Tanzanian medicinal plants. Acta Tropica 66 (1997) 79-83
15. Freiburghaus F., Kaminsky R., Nkunya M.H., and Brun R. Evaluation of African medicinal plants for their in vitro trypanocidal activity. Journal of Ethnopharmacology 55 (1996) 1-11
16. Ha J.Y., Min K.R., Kang S.-H., Kim J.S., Lee G.-I., Kang S.S., and Kim Y. Suppressive effects of triterpenoids on CINC-1 induction in interleukin-1beta-stimulated rat fibroblast NRK-49F cells. Archives of Pharmacal Research 20 (1997) 234-238
17. Herbert W.J., and Lumsden W.H. Trypanosoma brucei: a rapid "matching" method for estimating the host's parasitemia. Experimental Parasitology 40 (1976) 427-431
18. Kaminsky R., Chuma F., and Zweygarth E. Trypanosoma brucei brucei: expression of drug resistance in vitro. Experimental Parasitology 69 (1989) 281-289
19. Kaur K., Arora S., Hawthorne M.E., Kaur S., Kumar S., and Mehta R.G. A correlative study on antimutagenic and chemopreventive activity of Acacia auriculiformis A. Cunn. and Acacia nilotica (L.) Willd. Ex Del. Drug and Chemical Toxicology 25 (2002) 39-64
20. Kirira P.G., Rukunga G.M., Wanyonyi A.W., Muregi F.M., Gathirwa J.W., Muthaura C.N., Omar S.A., Tolo F., Mungai G.M., and Ndiege I.O. Anti-plasmodial activity and toxicity of extracts of plants used in traditional malaria therapy in Meru and Kilifi Districts of Kenya. Journal of Ethnopharmacology 106 (2006) 403-407
21. Kokwaro, J.O., 1976. Medicinal plants of East Africa. East African literature bureau, Nairobi, Kampala, Dar es Salaam, p. 125.
22. Kutney J.P., Hewitt G.M., Lee G., Piotrowska K., Roberts R., and Rettig S.J. Studies with tissue cultures of the Chinese herbal plant Tripterygium wilfordii. Isolation of metabolites of interest in rheumatoid arthritis, immunosuppression, and male contraceptive activity. Canadian Journal of Chemistry 70 (1992) 1455-1480
23. Lee J.S., Jung I.D., Jeong Y.-I., Lee C.-M., Shin Y.K., Lee S.-Y., Suh D.-S., Yoon M.-S., Lee K.-S., Choi Y.H., Chung H.Y., and Park Y.M. d-Pinitol inhibits Th1 polarization via the suppression of dendritic cells. International Immunopharmacology 7 (2007) 791-804
24. Lee J.S., Lee C.M., Jeong Y.I., Jung I.D., Kim B.H., Seong E.Y., Kim J.I., Choi I.W., Chung H.Y., and Park Y.M. d-Pinitol regulates Th1/Th2 balance via suppressing Th2 immune response in ovalbumin-induced asthma. FEBS Letters 581 (2007) 57-64
25. Maeser P., Grether-Buehler Y., Kaminsky R., and Brun R. An anticontamination cocktail for the in vitro isolation and cultivation of parasitic protozoa. Parasitology Research 88 (2002) 172-174
26. Mehlitz D. Investigations on the susceptibility of Mastomys natalensis to Trypanosoma (Trypanozoon) brucei gambiense (author's transl). Tropenmedizin und Parasitologie 29 (1978) 101-107
27. Okhoya N. Eradicating tsetse flies from Africa. Africa Recovery 17 (2003) 17
28. Peregrine A.S. Chemotherapy and delivery systems: haemoparasites. Veterinary Parasitology 54 (1994) 223-248
29. Prakash L., and Garg G. Chemical constituents of the roots of Millingtonia hortensis Linn. and Acacia nilotica (Linn.) Del. Journal of the Indian Chemical Society 58 (1981) 96-97
30. Sultana B., Anwar F., and Przybylski R. Antioxidant activity of phenolic components present in barks of Azadirachta indica, Terminalia arjuna, Acacia nilotica, and Eugenia jambolana Lam. trees. Food Chemistry 104 (2007) 1106-1114
31. Von Maydell H.-J. Arbres et arbustes du Sahel (1983), Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ), Eschborn pp. 111-114
32. Von Ostertag, R., 1920. Deutsches Kolonial-Lexikon. Schnee, H., Quelle & Meyer, Leipzig, p. 614.
33. Walker P.J. Capillary concentration technique applicable to infections of T. congolense in cattle. Transactions of the Royal Society of Tropical Medicine and Hygiene 66 (1972) 348
34. Watt J.M., and Breyer-Brandwijk M.G. The Medicinal and Poisonous Plants of Southern and Eastern Africa. (Being an account of their medicinal and other uses, chemical composition, pharmacological effects and toxicology in man and animal) (1962), E. & S. Livingstone, Ltd., Edinburg & London pp. 546-548
35. WHO, 2003. Traditional medicine. Fact sheet, 134.
36. Woo P.T. The haematocrit centrifuge technique for the diagnosis of African trypanosomiasis. Acta Tropica 27 (1970) 384-386
37. Yamashita K., Lu H., Lu J., Chen G., Yokoyama T., Sagara Y., Manabe M., and Kodama H. Effect of three triterpenoids, lupeol, betulin, and betulinic acid on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils. Clinica Chimica Acta 325 (2002) 91-96
38. Youan B.B.C., Coulibaly S., Miezan T.B., Doua F., and Bamba M. In vivo evaluation of sixteen plant extracts on mice inoculated with Trypanosoma brucei gambiense. Bulletin of the World Health Organization 75 (1997) 343-348