In vivo evaluation of sixteen plant extracts on mice inoculated with Trypanosoma brucei gambiense

Bulletin of the World Health Organization

Volumn 75, Issue 4, 1997, Pages 343-348

  Youan, B B C ^a   Coulibaly, S ^b   Miezan, T B ^c   Doua, F ^d   Bamba, M ^b  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIVERSITÉ NANGUI ABROGOUA   (Côte d’Ivoire)

^c Proj Clin Res on Trypanosomiasis   (Côte d’Ivoire)

^d PRCT ^*  (Côte d’Ivoire)

Author keywords

[No Author keywords available]

Indexed keywords

EFLORNITHINE; MELARSOPROL; PENTAMIDINE; PLANT EXTRACT;

AFRICAN TRYPANOSOMIASIS; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; COTE D'IVOIRE; DRUG EFFICACY; EVALUATION AND FOLLOW UP; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; TRYPANOSOMA GAMBIENSE;

ADMINISTRATION, ORAL; ANIMALS; COTE D'IVOIRE; EFLORNITHINE; INFUSIONS, PARENTERAL; INJECTIONS, INTRAPERITONEAL; MEDICINE, TRADITIONAL; MELARSOPROL; MICE; PENTAMIDINE; PLANT EXTRACTS; SODIUM CHLORIDE; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI GAMBIENSE; TRYPANOSOMIASIS, AFRICAN;

EID: 0030754975     PISSN: 00429686     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Dumas M, Boa YF. Human African trypanosomiasis. Handbook of clinical neurology. Amsterdam, Elsevier Science Publishers, 1988, 8: 339-344.
2. Epidemiology and control of African trypanosomiasis. Report of a WHO Expert Committee. Geneva, World Health Organization 1986 (WHO Technical Report Series, No. 739).
3. Adjanohoun E, Ake-Assi L. Contribution au recensement des plantes médicinales de Côte d'lvoire. Abidjan, Université Nationale de Côte d'lvoire, 1979.
4. Kerharo J, Adam JG. La pharmacopée sénégalaise traditionnelle. Plantes médicinales et toxiques. Paris, Vigot, 1974: 994.
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6. Bacchi CJ et al. In vivo effects of alpha-DL difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei. Molecular and biochemical parasitology, 1983, 7: 209-225.
7. Doua F et al. Treatment of human late-stage gambiense trypanosomiasis with alpha-difluoromethylornthine (eflornithine): efficacy and tolerance in 14 cases in Côte d'lvoire. American journal of tropical medicine and hygiene, 1987, 37: 525-533.