메뉴 건너뛰기




Volumn 98, Issue 3, 2008, Pages 148-155

Isolated limb perfusion with tumor necrosis factor and melphalan for non-resectable soft tissue sarcomas: Long-term results on efficacy and limb salvage in a selected group of patients

Author keywords

Advanced extremity sarcomas; Local treatment; Multidisciplinary team work; Prevention of amputation

Indexed keywords

MELPHALAN; TUMOR NECROSIS FACTOR;

EID: 50949108994     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.21081     Document Type: Article
Times cited : (43)

References (53)
  • 1
    • 0003964361 scopus 로고
    • American Cancer Society:, Atlanta, GA: American Cancer Society;
    • American Cancer Society: Cancer: Facts and figures. Atlanta, GA: American Cancer Society; 1995.
    • (1995) Cancer: Facts and figures
  • 2
    • 0029911378 scopus 로고    scopus 로고
    • The national cancer data base report on soft tissue sarcoma
    • Pollock RE, Karnell LH, Menck HR, et al.: The national cancer data base report on soft tissue sarcoma. Cancer 1996;78:2247-2257.
    • (1996) Cancer , vol.78 , pp. 2247-2257
    • Pollock, R.E.1    Karnell, L.H.2    Menck, H.R.3
  • 3
    • 0030850333 scopus 로고    scopus 로고
    • Prognostic factors for local control of sarcomas of the soft tissues managed by radiation and surgery
    • Spiro IJ, Gebhardt MC, Jennings LC, et al.: Prognostic factors for local control of sarcomas of the soft tissues managed by radiation and surgery. Semin Oncol 1997;24:540-546.
    • (1997) Semin Oncol , vol.24 , pp. 540-546
    • Spiro, I.J.1    Gebhardt, M.C.2    Jennings, L.C.3
  • 4
    • 0030148063 scopus 로고    scopus 로고
    • Local recurrence and survival in soft tissue sarcomas
    • Karakousis CP, Proimakis C, Rao U, et al.: Local recurrence and survival in soft tissue sarcomas. Ann Surg Oncol 1996;3:255-260.
    • (1996) Ann Surg Oncol , vol.3 , pp. 255-260
    • Karakousis, C.P.1    Proimakis, C.2    Rao, U.3
  • 6
    • 0026483502 scopus 로고
    • Comparison of amputation with limb-sparing operations for adult soft tissue sarcoma of the extremity
    • Williard WC, Hajdu SI, Casper ES, et al.: Comparison of amputation with limb-sparing operations for adult soft tissue sarcoma of the extremity. Ann Surg 1992;216:615-616.
    • (1992) Ann Surg , vol.216 , pp. 615-616
    • Williard, W.C.1    Hajdu, S.I.2    Casper, E.S.3
  • 7
    • 0026483502 scopus 로고
    • A comparison of amputation with limb-sparing operations for adult soft tissue sarcoma of the extremity
    • Stotter A: A comparison of amputation with limb-sparing operations for adult soft tissue sarcoma of the extremity. Ann Surg 1992;216:615-616.
    • (1992) Ann Surg , vol.216 , pp. 615-616
    • Stotter, A.1
  • 8
    • 0025730184 scopus 로고
    • Is local recurrence of minor importance for metastases in soft tissue sarcomas?
    • Gustafson P, Rooser B, Rydholm A: Is local recurrence of minor importance for metastases in soft tissue sarcomas? Cancer 1991;67:2083-2086.
    • (1991) Cancer , vol.67 , pp. 2083-2086
    • Gustafson, P.1    Rooser, B.2    Rydholm, A.3
  • 9
    • 0028294006 scopus 로고
    • Influence of surgical margins on outcome in patients with preoperatively irradiated extremity soft tissue sarcomas
    • Tanabe KK, Pollock RE, Ellis LM, et al.: Influence of surgical margins on outcome in patients with preoperatively irradiated extremity soft tissue sarcomas. Cancer. 1994;73:1652-1659.
    • (1994) Cancer , vol.73 , pp. 1652-1659
    • Tanabe, K.K.1    Pollock, R.E.2    Ellis, L.M.3
  • 10
    • 0027771008 scopus 로고
    • Results of preoperative neoadjuvant chemotherapy and surgery in the management of patients with soft tissue sarcoma
    • Rahoty P, Konya A: Results of preoperative neoadjuvant chemotherapy and surgery in the management of patients with soft tissue sarcoma. Eur J Surg Oncol 1993;19:641-645.
    • (1993) Eur J Surg Oncol , vol.19 , pp. 641-645
    • Rahoty, P.1    Konya, A.2
  • 11
    • 0026495379 scopus 로고
    • Neoadjuvant chemotherapy and combined conservative treatment of soft tissue sarcoma in the adult
    • Cany L, Bui NB, Stockle E, et al.: Neoadjuvant chemotherapy and combined conservative treatment of soft tissue sarcoma in the adult. Bull Cancer 1992;79:1077-1085.
    • (1992) Bull Cancer , vol.79 , pp. 1077-1085
    • Cany, L.1    Bui, N.B.2    Stockle, E.3
  • 12
    • 0019493014 scopus 로고
    • Preoperative radiation therapy for sarcoma of soft tissue
    • Suit HD, Proppe KH, Mankin HJ, et al.: Preoperative radiation therapy for sarcoma of soft tissue. Cancer 1981;47:2269-2274.
    • (1981) Cancer , vol.47 , pp. 2269-2274
    • Suit, H.D.1    Proppe, K.H.2    Mankin, H.J.3
  • 13
    • 0021278515 scopus 로고
    • Limb salvage for skeletal and soft tissue sarcomas: Multidisciplinary preoperative therapy
    • Eilber FR, Morton DL, Eckhart J, et al.: Limb salvage for skeletal and soft tissue sarcomas: Multidisciplinary preoperative therapy. Cancer 1984;53:2579-2584.
    • (1984) Cancer , vol.53 , pp. 2579-2584
    • Eilber, F.R.1    Morton, D.L.2    Eckhart, J.3
  • 14
    • 0025876065 scopus 로고
    • Brachytherapy and function-saving resection of soft tissue sarcoma arising in the limb
    • Shiu MH, Hilaris BS, Harrison LB: Brachytherapy and function-saving resection of soft tissue sarcoma arising in the limb. Int J Radiat Oncol Biol Phys 1991; 1485-1492.
    • (1991) Int J Radiat Oncol Biol Phys , pp. 1485-1492
    • Shiu, M.H.1    Hilaris, B.S.2    Harrison, L.B.3
  • 15
    • 0028339992 scopus 로고
    • Local control of soft tissue sarcoma of the extremity. The experience of a multidisciplinary sarcoma group with definitive surgery and radiotherapy
    • Wilson AN, Davis A, Bell RS, et al.: Local control of soft tissue sarcoma of the extremity. The experience of a multidisciplinary sarcoma group with definitive surgery and radiotherapy. Eur J Cancer 1994;30A:746-751.
    • (1994) Eur J Cancer , vol.30 A , pp. 746-751
    • Wilson, A.N.1    Davis, A.2    Bell, R.S.3
  • 16
    • 4344690868 scopus 로고    scopus 로고
    • Isolated extremity perfusion with TNF-alpha and melphalan in unresectable soft tissue sarcoma. Indications, principle and technique
    • Taeger G, Ruchholtz S, Niebel W, et al.: Isolated extremity perfusion with TNF-alpha and melphalan in unresectable soft tissue sarcoma. Indications, principle and technique. Unfallchirurg 2004;107:619-623.
    • (2004) Unfallchirurg , vol.107 , pp. 619-623
    • Taeger, G.1    Ruchholtz, S.2    Niebel, W.3
  • 17
    • 0027358516 scopus 로고
    • Systemic leakage during Isolated limb perfusion for melanoma
    • Klaase JM, Kroon BB, van Geel AN, et al.: Systemic leakage during Isolated limb perfusion for melanoma. Br J Surg 1993;80:1124-1126.
    • (1993) Br J Surg , vol.80 , pp. 1124-1126
    • Klaase, J.M.1    Kroon, B.B.2    van Geel, A.N.3
  • 18
    • 78651031713 scopus 로고
    • Chemotherapy of cancer: Regional perfusion utilizing an extracorporeal circuit
    • Creech O, Krementz ET, Ryan RF, et al.: Chemotherapy of cancer: Regional perfusion utilizing an extracorporeal circuit. Ann Surg 1958;148:616-632.
    • (1958) Ann Surg , vol.148 , pp. 616-632
    • Creech, O.1    Krementz, E.T.2    Ryan, R.F.3
  • 19
    • 0026559430 scopus 로고
    • Isolated limb perfusion for melanoma: Effectiveness and toxicity of cisplatin compared with that of melphalan and other drugs
    • Thompson JF, Gianoutsos MP: Isolated limb perfusion for melanoma: Effectiveness and toxicity of cisplatin compared with that of melphalan and other drugs. Worl J Surg 1992;16:227-233.
    • (1992) Worl J Surg , vol.16 , pp. 227-233
    • Thompson, J.F.1    Gianoutsos, M.P.2
  • 20
    • 0024358425 scopus 로고
    • Results of regional isolation perfusion with cytostatics in patients with soft tissue tumors of the extremities
    • Klaase JM, Kroon BB, Benckhuijsen C, et al.: Results of regional isolation perfusion with cytostatics in patients with soft tissue tumors of the extremities. Cancer 1989;64:616-621.
    • (1989) Cancer , vol.64 , pp. 616-621
    • Klaase, J.M.1    Kroon, B.B.2    Benckhuijsen, C.3
  • 21
    • 0028329179 scopus 로고
    • Phase II study on neoadjuvant hyperthermic-antiblastic perfusion with doxorubicin in patients with intermediate or high grade sarcomas
    • Rossi CR, Vecchiato A, Foletto M, et al.: Phase II study on neoadjuvant hyperthermic-antiblastic perfusion with doxorubicin in patients with intermediate or high grade sarcomas. Cancer 1994;73:2140-2146.
    • (1994) Cancer , vol.73 , pp. 2140-2146
    • Rossi, C.R.1    Vecchiato, A.2    Foletto, M.3
  • 22
    • 0026531756 scopus 로고
    • High-dose recombinant tumor necrosis factor in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma
    • Lienard D, Ewalenko P, Delmotte JJ, et al.: High-dose recombinant tumor necrosis factor in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma. J Clin Oncol 1992;10:52-60.
    • (1992) J Clin Oncol , vol.10 , pp. 52-60
    • Lienard, D.1    Ewalenko, P.2    Delmotte, J.J.3
  • 23
    • 0009885824 scopus 로고    scopus 로고
    • Isolated limb perfusion with tumor necrosis factor and melphalan for limb salvage in 186 patients with locally advanced soft tissue extremity sarcomas. The cumulative multicenter European experience
    • discussion 764-5
    • Eggermont AM, Schraffordt, Koops H, Klausner JM, et al.: Isolated limb perfusion with tumor necrosis factor and melphalan for limb salvage in 186 patients with locally advanced soft tissue extremity sarcomas. The cumulative multicenter European experience. Ann Surg 1996;224:756-764; discussion 764-5.
    • (1996) Ann Surg , vol.224 , pp. 756-764
    • Eggermont, A.M.1    Schraffordt2    Koops, H.3    Klausner, J.M.4
  • 24
    • 0030437624 scopus 로고    scopus 로고
    • Treatment of recurrent sarcoma of the extremity by isolated limb perfusion using tumor necrosis factor alpha and melphalan
    • Santinami M, Deraco M, Azzarelli A, et al.: Treatment of recurrent sarcoma of the extremity by isolated limb perfusion using tumor necrosis factor alpha and melphalan. Tumori 1996;82:579-584.
    • (1996) Tumori , vol.82 , pp. 579-584
    • Santinami, M.1    Deraco, M.2    Azzarelli, A.3
  • 25
    • 0033013236 scopus 로고    scopus 로고
    • Multifocal soft tissue sarcoma: Limb salvage following hyperthermic isolated limb prefusion with high-dose tumor necrosis factor and melphalan
    • Lev-Chelouche D, Abu-Abeid S, Kollander Y, Meller I, et al.: Multifocal soft tissue sarcoma: Limb salvage following hyperthermic isolated limb prefusion with high-dose tumor necrosis factor and melphalan. J Surg Oncol 1999;70:185-189.
    • (1999) J Surg Oncol , vol.70 , pp. 185-189
    • Lev-Chelouche, D.1    Abu-Abeid, S.2    Kollander, Y.3    Meller, I.4
  • 26
    • 0030889278 scopus 로고    scopus 로고
    • High dose tumor necrosis factor alpha and melphalan administrated via isolated limb perfusion for advanced limb soft tissues sarcoma results in >90% response rate and limb preservation
    • Gutman M, Inbar M, Lev-Shlush D, et al.: High dose tumor necrosis factor alpha and melphalan administrated via isolated limb perfusion for advanced limb soft tissues sarcoma results in >90% response rate and limb preservation. Cancer 1997;79:1129-1137.
    • (1997) Cancer , vol.79 , pp. 1129-1137
    • Gutman, M.1    Inbar, M.2    Lev-Shlush, D.3
  • 27
    • 0141787019 scopus 로고    scopus 로고
    • Isolated limb perfusion with tumor necrosis factor-alpha and melphalan for patients with unresectable soft tissue sarcoma of the extremities
    • Noorda EM, Vrouenraets BC, Nieweg OE, et al.: Isolated limb perfusion with tumor necrosis factor-alpha and melphalan for patients with unresectable soft tissue sarcoma of the extremities. Cancer 2003;98:1483-1490.
    • (2003) Cancer , vol.98 , pp. 1483-1490
    • Noorda, E.M.1    Vrouenraets, B.C.2    Nieweg, O.E.3
  • 28
    • 33744955317 scopus 로고    scopus 로고
    • Efficiency of recombinant human TNF in human cancer therapy
    • Lejeune FJ, Lienard D, Matter M, et al.: Efficiency of recombinant human TNF in human cancer therapy. Cancer Immun 2006;6:6.
    • (2006) Cancer Immun , vol.6 , pp. 6
    • Lejeune, F.J.1    Lienard, D.2    Matter, M.3
  • 29
    • 0033229740 scopus 로고    scopus 로고
    • soft tissue limb sarcomas: Italian clinical trials with hyperthermic antiblastic perfusion
    • Rossi CR, Foletto M, Di Filippo F, et al.: soft tissue limb sarcomas: Italian clinical trials with hyperthermic antiblastic perfusion. Cancer 1999;86:1742-1749.
    • (1999) Cancer , vol.86 , pp. 1742-1749
    • Rossi, C.R.1    Foletto, M.2    Di Filippo, F.3
  • 30
    • 0032897078 scopus 로고    scopus 로고
    • Prerequisites for effective isolated limb perfusion using tumor necrosis factor-alpha and melphalan in rats
    • De Wilt JH, Manusama ER, van Tiel ST, et al.: Prerequisites for effective isolated limb perfusion using tumor necrosis factor-alpha and melphalan in rats. Br J Cancer. 1999;80:161-166.
    • (1999) Br J Cancer , vol.80 , pp. 161-166
    • De Wilt, J.H.1    Manusama, E.R.2    van Tiel, S.T.3
  • 31
    • 0033636988 scopus 로고    scopus 로고
    • Limb salvage by neoadjuvant isolated limb perfusion with TNF alpha and melphalan for non-resectable soft tissue sarcoma of the extremities
    • Lejeune FJ, Pujol N, Lienard D, et al.: Limb salvage by neoadjuvant isolated limb perfusion with TNF alpha and melphalan for non-resectable soft tissue sarcoma of the extremities. Eur J Surg Oncol 2000;26:669-678.
    • (2000) Eur J Surg Oncol , vol.26 , pp. 669-678
    • Lejeune, F.J.1    Pujol, N.2    Lienard, D.3
  • 32
    • 0021366779 scopus 로고
    • Soft tissue sarcomas of adults; study of pathological prognostic variables and definition of a histological grading system
    • Trojani M, Contesso G, Coindre JM, et al.: Soft tissue sarcomas of adults; study of pathological prognostic variables and definition of a histological grading system. Int J Cancer 1984;33:37-42.
    • (1984) Int J Cancer , vol.33 , pp. 37-42
    • Trojani, M.1    Contesso, G.2    Coindre, J.M.3
  • 33
    • 0031023138 scopus 로고    scopus 로고
    • Comparative study of the National Cancer Institute and French Federation of Cancer Center Sarcoma Group grading systems in a population of 410 adult patients with soft tissue sarcoma
    • Guillou L, Coindre JM, Bonichon F, et al.: Comparative study of the National Cancer Institute and French Federation of Cancer Center Sarcoma Group grading systems in a population of 410 adult patients with soft tissue sarcoma. J Clin Oncol 1997;15:350-362.
    • (1997) J Clin Oncol , vol.15 , pp. 350-362
    • Guillou, L.1    Coindre, J.M.2    Bonichon, F.3
  • 36
    • 0029258638 scopus 로고
    • Administration of high-dose tumor necrosis factor alpha by isolation perfusion of the limbs. Rationale and results
    • Lejeune FJ, Lienard D, Eggermont AM, et al.: Administration of high-dose tumor necrosis factor alpha by isolation perfusion of the limbs. Rationale and results. J Infus Chemother 1995;5:73-81.
    • (1995) J Infus Chemother , vol.5 , pp. 73-81
    • Lejeune, F.J.1    Lienard, D.2    Eggermont, A.M.3
  • 37
    • 0037225741 scopus 로고    scopus 로고
    • Isolated limb perfusion: Distinct tourniquet and tumor necrosis factor effects on the early hemodynamic response
    • Christoforidis D, Chassot PG, Mosimann F, et al.: Isolated limb perfusion: Distinct tourniquet and tumor necrosis factor effects on the early hemodynamic response. Arch Surg 2003;138:17-25.
    • (2003) Arch Surg , vol.138 , pp. 17-25
    • Christoforidis, D.1    Chassot, P.G.2    Mosimann, F.3
  • 38
    • 0020365748 scopus 로고
    • Dosimetry in isolation perfusion of the limbs by assessment of perfused tissue volume and grading of toxic tissue reactions
    • Wieberdink J, Benckhuijsen C, Braat RP, et al.: Dosimetry in isolation perfusion of the limbs by assessment of perfused tissue volume and grading of toxic tissue reactions. Eur J Cancer Clin Oncol 1982;18:905-910.
    • (1982) Eur J Cancer Clin Oncol , vol.18 , pp. 905-910
    • Wieberdink, J.1    Benckhuijsen, C.2    Braat, R.P.3
  • 39
    • 84878759997 scopus 로고    scopus 로고
    • WHO handbook for reporting results of cancer treatment, WHO Offset Publication No. 48, Geneva: WHO; 1979.
    • WHO handbook for reporting results of cancer treatment, WHO Offset Publication No. 48, Geneva: WHO; 1979.
  • 40
    • 0029098875 scopus 로고    scopus 로고
    • Systemic leakage and side effects of tumor necrosis factor alpha administered via isolated limb perfusion can be manipulated by flow rate adjustment
    • Sorkin P, Abu-Abid S, Lev D, et al.: Systemic leakage and side effects of tumor necrosis factor alpha administered via isolated limb perfusion can be manipulated by flow rate adjustment. Arch Surg 1996;13:1079-1084.
    • (1996) Arch Surg , vol.13 , pp. 1079-1084
    • Sorkin, P.1    Abu-Abid, S.2    Lev, D.3
  • 41
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • Therasse P, Arbuck SG, Eisenhauer EA, et al.: New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 2000;92:205-216.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3
  • 43
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Statist Assoc 1958;53:457-481.
    • (1958) J Am Statist Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 44
    • 0030305457 scopus 로고    scopus 로고
    • R: A language for data analysis and graphics
    • Ihaka R, Gentleman R: R: A language for data analysis and graphics. J Comput Graph Statist 1996;5:299-314.
    • (1996) J Comput Graph Statist , vol.5 , pp. 299-314
    • Ihaka, R.1    Gentleman, R.2
  • 45
    • 0032719726 scopus 로고    scopus 로고
    • Limb desmoid tumors: A possible role for isolated limb perfusion with tumor necrosis factor-alpha and melphalan
    • Lev-Chelouche D, Abu-Abeid S, Nakache R, et al.: Limb desmoid tumors: A possible role for isolated limb perfusion with tumor necrosis factor-alpha and melphalan. Surgery 1999;126:963-967.
    • (1999) Surgery , vol.126 , pp. 963-967
    • Lev-Chelouche, D.1    Abu-Abeid, S.2    Nakache, R.3
  • 46
    • 0032873149 scopus 로고    scopus 로고
    • Long-term functional morbidity after mild hyperthermic isolated limb perfusion with melphalan
    • Vrouenraets BC, in't Veld GJ, Nieweg OE, et al.: Long-term functional morbidity after mild hyperthermic isolated limb perfusion with melphalan. Eur J Surg Oncol 1999;25:503-508.
    • (1999) Eur J Surg Oncol , vol.25 , pp. 503-508
    • Vrouenraets, B.C.1    in't Veld, G.J.2    Nieweg, O.E.3
  • 47
    • 0031945945 scopus 로고    scopus 로고
    • Feasibility and efficacy of external beam radiotherapy after hyperthermic isolated limb perfusion with TNF-alpha and melphalan for limb-saving treatment in locally advanced extremity soft-tissue sarcoma
    • Olieman AF, Pras E, van Ginkel RJ, et al.: Feasibility and efficacy of external beam radiotherapy after hyperthermic isolated limb perfusion with TNF-alpha and melphalan for limb-saving treatment in locally advanced extremity soft-tissue sarcoma. Int J Radiat Oncol Biol Phys 1998;40:807-814.
    • (1998) Int J Radiat Oncol Biol Phys , vol.40 , pp. 807-814
    • Olieman, A.F.1    Pras, E.2    van Ginkel, R.J.3
  • 48
    • 0000409279 scopus 로고    scopus 로고
    • Limb salvage by isolation limb perfusion with tumor necrosis factor alpha and melphalan for locally advanced soft tissue sarcomas: Results of 270 perfusions in 246 patients
    • Abstr
    • Eggermont AM, Schraffordt Koops H, Klausner JM, et al.: Limb salvage by isolation limb perfusion with tumor necrosis factor alpha and melphalan for locally advanced soft tissue sarcomas: Results of 270 perfusions in 246 patients. Proc Am Soc Clin Oncol 1999;11:497 (Abstr).
    • (1999) Proc Am Soc Clin Oncol , vol.11 , pp. 497
    • Eggermont, A.M.1    Schraffordt Koops, H.2    Klausner, J.M.3
  • 49
    • 0037266665 scopus 로고    scopus 로고
    • Fifty tumor necrosis factor-based isolated limb perfusions for limb salvage in patients older than 75 years with limb-threatening soft tissue sarcomas and other extremity tumors
    • van Etten B, de Wilt JH, Eggermont AM: Fifty tumor necrosis factor-based isolated limb perfusions for limb salvage in patients older than 75 years with limb-threatening soft tissue sarcomas and other extremity tumors. Ann Surg Oncol 2003;10:32-337.
    • (2003) Ann Surg Oncol , vol.10 , pp. 32-337
    • van Etten, B.1    de Wilt, J.H.2    Eggermont, A.M.3
  • 50
    • 21144457435 scopus 로고    scopus 로고
    • Isolated limb perfusions with tumor necrosis factor and melphalan for locally recurrent soft tissue sarcoma in previously irradiated limbs
    • Epub March 31
    • Lans TE, Grunhagen DJ, de Wilt JH, et al.: Isolated limb perfusions with tumor necrosis factor and melphalan for locally recurrent soft tissue sarcoma in previously irradiated limbs. Ann Surg Oncol 2005;12:406-411. Epub 2005 March 31.
    • (2005) Ann Surg Oncol 2005 , vol.12 , pp. 406-411
    • Lans, T.E.1    Grunhagen, D.J.2    de Wilt, J.H.3
  • 51
    • 25444508401 scopus 로고    scopus 로고
    • Bonvalot S, Laplanche A, Lejeune F, et al.: Limb salvage with isolated perfusion for soft tissue sarcoma: Could less TNF-alpha be better? Ann Oncol 2005;16:1061-1068. Epub 2005 June 1.
    • Bonvalot S, Laplanche A, Lejeune F, et al.: Limb salvage with isolated perfusion for soft tissue sarcoma: Could less TNF-alpha be better? Ann Oncol 2005;16:1061-1068. Epub 2005 June 1.
  • 52
    • 0030737741 scopus 로고    scopus 로고
    • Complications of combined radiotherapy and isolated limb perfusion with tumor necrosis factor alpha ± interferon gamma and melphalan in patients with irresectable soft tissue tumors
    • Vrouenraets BC, Keus RB, Nieweg OE, et al.: Complications of combined radiotherapy and isolated limb perfusion with tumor necrosis factor alpha ± interferon gamma and melphalan in patients with irresectable soft tissue tumors. J Surg Oncol 1997;65:88-94.
    • (1997) J Surg Oncol , vol.65 , pp. 88-94
    • Vrouenraets, B.C.1    Keus, R.B.2    Nieweg, O.E.3
  • 53
    • 0029913782 scopus 로고    scopus 로고
    • Analysis of prognostic factors in 1,041 patients with localized soft tissue sarcomas of the extremities
    • Pisters PW, Leung DH, Woodruff J, et al.: Analysis of prognostic factors in 1,041 patients with localized soft tissue sarcomas of the extremities. J Clin Oncol 1996;14:1679-1689.
    • (1996) J Clin Oncol , vol.14 , pp. 1679-1689
    • Pisters, P.W.1    Leung, D.H.2    Woodruff, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.