-
1
-
-
0345596439
-
Isolated hepatic perfusion with tumor necrosis factor and melphalan for unresectable cancers confined to the liver
-
Alexander HR, Bartlett DL, Libutti SK, Fraker DL, Moser T and Rosenberg SA (1998) Isolated hepatic perfusion with tumor necrosis factor and melphalan for unresectable cancers confined to the liver. J Clin Oncol 12: 1479-1489
-
(1998)
J Clin Oncol
, vol.12
, pp. 1479-1489
-
-
Alexander, H.R.1
Bartlett, D.L.2
Libutti, S.K.3
Fraker, D.L.4
Moser, T.5
Rosenberg, S.A.6
-
2
-
-
0023130601
-
Studies of the antitumor efficacy of systemically administered recombinant tumor necrosis factor against several murine tumors in vivo
-
Asher AL, Mule JJ, Reichert CM, Shiloni E and Rosenberg SA (1987) Studies of the antitumor efficacy of systemically administered recombinant tumor necrosis factor against several murine tumors in vivo. J Immunol 138: 963-974
-
(1987)
J Immunol
, vol.138
, pp. 963-974
-
-
Asher, A.L.1
Mule, J.J.2
Reichert, C.M.3
Shiloni, E.4
Rosenberg, S.A.5
-
3
-
-
0023885868
-
Regional perfusion treatment with melphalan for melanoma in a limb: An evaluation of drug kinetics
-
Benckhuijsen C, Kroon BBR, Van Geel AN and Wieberdink J (1988) Regional perfusion treatment with melphalan for melanoma in a limb: an evaluation of drug kinetics. Eur J Surg Oncol 14: 157-163
-
(1988)
Eur J Surg Oncol
, vol.14
, pp. 157-163
-
-
Benckhuijsen, C.1
Kroon, B.B.R.2
Van Geel, A.N.3
Wieberdink, J.4
-
4
-
-
0030953617
-
Isolated hepatic perfusion in the pig with TNF-α with and without melphalan
-
Borel Rinkes IHM, de Vries MR, Jonker AM, Swaak TJG, Hack CE, Nooijen PTGA, Wiggers T and Eggermont AMM (1997) Isolated hepatic perfusion in the pig with TNF-α with and without melphalan. Br J Cancer 75: 1447-1453
-
(1997)
Br J Cancer
, vol.75
, pp. 1447-1453
-
-
Borel Rinkes, I.H.M.1
De Vries, M.R.2
Jonker, A.M.3
Swaak, T.J.G.4
Hack, C.E.5
Nooijen, P.T.G.A.6
Wiggers, T.7
Eggermont, A.M.M.8
-
5
-
-
0026757715
-
Selective species specificity of tumor necrosis factor for toxicity in the mouse
-
Broukaert P, Libert C, Everaerdt B and Fiers W (1992) Selective species specificity of tumor necrosis factor for toxicity in the mouse. Lymphokine Cytokine Res 11: 193-196
-
(1992)
Lymphokine Cytokine Res
, vol.11
, pp. 193-196
-
-
Broukaert, P.1
Libert, C.2
Everaerdt, B.3
Fiers, W.4
-
6
-
-
0027940288
-
Melphalan uptake, hyperthermic synergism and drug resistance in a human cell culture model for the isolated limb perfusions of melanoma
-
Clark J, Grabs AJ, Parson PG, Smithers BM, Addison RS and Roberts MS (1994) Melphalan uptake, hyperthermic synergism and drug resistance in a human cell culture model for the isolated limb perfusions of melanoma. Melanoma Res 4: 365-370
-
(1994)
Melanoma Res
, vol.4
, pp. 365-370
-
-
Clark, J.1
Grabs, A.J.2
Parson, P.G.3
Smithers, B.M.4
Addison, R.S.5
Roberts, M.S.6
-
7
-
-
0348198386
-
Determination of melphalan and hydrolysis products in body fluids by GC-MS
-
De Boeck G, van Cauwenberghe K, Eggermont AMM, van Oosterom AT and de Bruijn EA (1997) Determination of melphalan and hydrolysis products in body fluids by GC-MS. J High Res Chromat 20: 697-700
-
(1997)
J High Res Chromat
, vol.20
, pp. 697-700
-
-
De Boeck, G.1
Van Cauwenberghe, K.2
Eggermont, A.M.M.3
Van Oosterom, A.T.4
De Bruijn, E.A.5
-
8
-
-
0031637434
-
Isolated hepatic perfusion with tumor necrosis factor-α(TNFα) and melphalan
-
De Vries MR, Borel Rinkes IHM, van de Velde CJH, Wiggers T, Tollenaar RAEM, Kuppen PJK, Vahnmeijer A and Eggermont (1998) Isolated hepatic perfusion with tumor necrosis factor-α(TNFα) and melphalan. Rec Results Cancer Res 147: 107-119
-
(1998)
Rec Results Cancer Res
, vol.147
, pp. 107-119
-
-
De Vries, M.R.1
Borel Rinkes, I.H.M.2
Van De Velde, C.J.H.3
Wiggers, T.4
Tollenaar, R.A.E.M.5
Kuppen, P.J.K.6
Vahnmeijer, A.7
Eggermont8
-
9
-
-
0029541070
-
Treatment of melanoma in-transit metastases confined to the limb
-
Eggermont AMM (1996) Treatment of melanoma in-transit metastases confined to the limb. Cancer Surv 26: 335-349
-
(1996)
Cancer Surv
, vol.26
, pp. 335-349
-
-
Eggermont, A.M.M.1
-
10
-
-
0029738520
-
Isolated limb perfusion with high-dose tumor necrosis factor-α in combination with interferon-γ and melphalan for non-resectable extremity soft tissue sarcomas: A multicenter trial
-
Eggermont AMM, Schraffordt Koops H. Liénard D, Kroon BBR, van Geel AN, Hoekstra HJ and Lejeune FJ (1996a) Isolated limb perfusion with high-dose tumor necrosis factor-α in combination with interferon-γ and melphalan for non-resectable extremity soft tissue sarcomas: a multicenter trial. J Clin Oncol 14: 2653-2665
-
(1996)
J Clin Oncol
, vol.14
, pp. 2653-2665
-
-
Eggermont, A.M.M.1
Schraffordt Koops, H.2
Liénard, D.3
Kroon, B.B.R.4
Van Geel, A.N.5
Hoekstra, H.J.6
Lejeune, F.J.7
-
11
-
-
0009885824
-
Isolated limb perfusion with tumor necrosis factor and melphalan for limb salvage in 186 patients with locally advanced soft tissue extremity sarcomas: The cumulative multicenter european experience
-
Eggermont AMM, Schraffordt Koops H, Klausner J, Kroon BBR, Schlag PM, Liénard D, van Geel AN, Hoekstra HJ, Meller I, Nieweg OE, Kettelhack C, Ben-Ari G, Pector JC and Lejeune FJ (1996b) Isolated limb perfusion with tumor necrosis factor and melphalan for limb salvage in 186 patients with locally advanced soft tissue extremity sarcomas: the cumulative multicenter European experience. Ann Surg 224: 756-765
-
(1996)
Ann Surg
, vol.224
, pp. 756-765
-
-
Eggermont, A.M.M.1
Schraffordt Koops, H.2
Klausner, J.3
Kroon, B.B.R.4
Schlag, P.M.5
Liénard, D.6
Van Geel, A.N.7
Hoekstra, H.J.8
Meller, I.9
Nieweg, O.E.10
Kettelhack, C.11
Ben-Ari, G.12
Pector, J.C.13
Lejeune, F.J.14
-
13
-
-
0026568694
-
Dual role of tumor necrosis factor-α in angiogenesis
-
Fajardo LF, Kwan HH, Kowalski J, Prionas SD and Allison AC (1992) Dual role of tumor necrosis factor-α in angiogenesis. Am J Pathol 140: 539-544
-
(1992)
Am J Pathol
, vol.140
, pp. 539-544
-
-
Fajardo, L.F.1
Kwan, H.H.2
Kowalski, J.3
Prionas, S.D.4
Allison, A.C.5
-
14
-
-
0028625512
-
Use of tumor necrosis factor in isolated hepatic perfusion
-
Fraker DL, Alexander HR and Thom AK (1994) Use of tumor necrosis factor in isolated hepatic perfusion. Circ Shock 44: 45-50
-
(1994)
Circ Shock
, vol.44
, pp. 45-50
-
-
Fraker, D.L.1
Alexander, H.R.2
Thom, A.K.3
-
15
-
-
0030058843
-
Treatment of patients with melanoma of the extremity using hyperthermic isolated limb perfusion with melphalan, tumor necrosis factor, and interferon gamma: Results of a tumor necrosis factor dose-escalation study
-
Fraker DL, Alexander HR, Andrich M and Rosenburg SA (1996) Treatment of patients with melanoma of the extremity using hyperthermic isolated limb perfusion with melphalan, tumor necrosis factor, and interferon gamma: results of a tumor necrosis factor dose-escalation study. J Clin Oncol 14: 479-489
-
(1996)
J Clin Oncol
, vol.14
, pp. 479-489
-
-
Fraker, D.L.1
Alexander, H.R.2
Andrich, M.3
Rosenburg, S.A.4
-
16
-
-
0027275758
-
Low-dose tumour necrosis factor α and melphalan in hyperthermic isolated limb perfusion
-
Hill S, Fawcett WJ, Sheldon J, Soni N, Williams T and Thomas JM (1993) Low-dose tumour necrosis factor α and melphalan in hyperthermic isolated limb perfusion. Br J Surg 80: 995-997
-
(1993)
Br J Surg
, vol.80
, pp. 995-997
-
-
Hill, S.1
Fawcett, W.J.2
Sheldon, J.3
Soni, N.4
Williams, T.5
Thomas, J.M.6
-
17
-
-
0024358425
-
Results of regional isolation perfusion with cytostatics in patients with soft tissue tumors of the extremities
-
Klaase JM, Kroon BBR, Benckhuijsen C, van Geel AN, Albus-Lutter CE and Wieberdink J (1989). Results of regional isolation perfusion with cytostatics in patients with soft tissue tumors of the extremities. Cancer 64: 616-621
-
(1989)
Cancer
, vol.64
, pp. 616-621
-
-
Klaase, J.M.1
Kroon, B.B.R.2
Benckhuijsen, C.3
Van Geel, A.N.4
Albus-Lutter, C.E.5
Wieberdink, J.6
-
18
-
-
0026666806
-
Enhanced sensitivity of human colon tumor cell lines in vitro in response to thermochemoimmunotherapy
-
Klostergaard J, Leroux E, Siddik ZH, Khodadadian M and Tomasovic SP (1992) Enhanced sensitivity of human colon tumor cell lines in vitro in response to thermochemoimmunotherapy. Cancer Res 52: 5271-5277
-
(1992)
Cancer Res
, vol.52
, pp. 5271-5277
-
-
Klostergaard, J.1
Leroux, E.2
Siddik, Z.H.3
Khodadadian, M.4
Tomasovic, S.P.5
-
19
-
-
0023021899
-
Serum-free in vitro bioassay for the detection of tumor necrosis factor
-
Kramer SM and Carver ME (1986) Serum-free in vitro bioassay for the detection of tumor necrosis factor. J Immunol Methods 93: 201-206
-
(1986)
J Immunol Methods
, vol.93
, pp. 201-206
-
-
Kramer, S.M.1
Carver, M.E.2
-
22
-
-
0026531756
-
High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma
-
Liénard D, Ewalenko P, Delmotte JJ, Renard N and Lejeune FJ (1992) High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma. J Clin Oncol 10: 52-60
-
(1992)
J Clin Oncol
, vol.10
, pp. 52-60
-
-
Liénard, D.1
Ewalenko, P.2
Delmotte, J.J.3
Renard, N.4
Lejeune, F.J.5
-
23
-
-
0029985727
-
Synergistic antitumour effect of recombinant human tumour necrosis factor α with melphalan in isolated limb perfusion in the rat
-
Manusama ER, Nooijen PTGA, Stavast J, Durante NMC, Marquet RL and Eggermont AMM (1996) Synergistic antitumour effect of recombinant human tumour necrosis factor α with melphalan in isolated limb perfusion in the rat. Br J Surg 83: 551-555
-
(1996)
Br J Surg
, vol.83
, pp. 551-555
-
-
Manusama, E.R.1
Nooijen, P.T.G.A.2
Stavast, J.3
Durante, N.M.C.4
Marquet, R.L.5
Eggermont, A.M.M.6
-
24
-
-
0023864018
-
Synergistic effects of recombinant human tumor necrosis factor and hyperthermia on in vitro cytotoxicity and artificial metastasis
-
Niitsu Y, Watanabe, Umeno H, Sone H, Neda H, Yamauchi N, Maeda M and Urushizaki I (1988) Synergistic effects of recombinant human tumor necrosis factor and hyperthermia on in vitro cytotoxicity and artificial metastasis. Cancer Res 48: 654-657
-
(1988)
Cancer Res
, vol.48
, pp. 654-657
-
-
Niitsu, Y.1
Watanabe2
Umeno, H.3
Sone, H.4
Neda, H.5
Yamauchi, N.6
Maeda, M.7
Urushizaki, I.8
-
25
-
-
0030456873
-
Synergistic anti-tumour effects of TNF-α and melphalan in an isolated limb perfusion model of rat sarcoma: A histopathologic, immunohistochemical and electron microscopic study
-
Nooijen PTGA, Manusama ER, Eggermont AMM, Schalkwijk L, Stavast J, Marquet RL, de Waal RMW and Ruiter DJ (1996a) Synergistic anti-tumour effects of TNF-α and melphalan in an isolated limb perfusion model of rat sarcoma: a histopathologic, immunohistochemical and electron microscopic study. Br J Cancer 74: 1908-1915
-
(1996)
Br J Cancer
, vol.74
, pp. 1908-1915
-
-
Nooijen, P.T.G.A.1
Manusama, E.R.2
Eggermont, A.M.M.3
Schalkwijk, L.4
Stavast, J.5
Marquet, R.L.6
De Waal, R.M.W.7
Ruiter, D.J.8
-
26
-
-
0029993389
-
Transient induction of E-selectin expression following TNFalpha-based isolated limb perfusion in melanoma and sarcoma patients is not tumor specific
-
Nooijen PTGA, Eggermont AMM, Verbeck MM, Schalkwijk L, Buurman WA, de Waal RMW and Ruiter DJ (1996b) Transient induction of E-selectin expression following TNFalpha-based isolated limb perfusion in melanoma and sarcoma patients is not tumor specific. J Immunother Emphasis Tumor Immunol 19: 33-44
-
(1996)
J Immunother Emphasis Tumor Immunol
, vol.19
, pp. 33-44
-
-
Nooijen, P.T.G.A.1
Eggermont, A.M.M.2
Verbeck, M.M.3
Schalkwijk, L.4
Buurman, W.A.5
De Waal, R.M.W.6
Ruiter, D.J.7
-
27
-
-
0027090125
-
Optimization of isolated hyperthermic limb perfusion
-
Omlor G, Gross G, Ecker KW, Burger I and Feifel G (1992) Optimization of isolated hyperthermic limb perfusion. World J Surg 16: 1117-1119
-
(1992)
World J Surg
, vol.16
, pp. 1117-1119
-
-
Omlor, G.1
Gross, G.2
Ecker, K.W.3
Burger, I.4
Feifel, G.5
-
28
-
-
0000170217
-
Hyperthermic isolated limb perfusion (HILP) with tumor necrosis factor alpha (TNF) alone for metastatic in-transit melanoma
-
Posner M, Liénard D, Lejeune FJ, Rosenfelder D and Kirkwood J (1994) Hyperthermic isolated limb perfusion (HILP) with tumor necrosis factor alpha (TNF) alone for metastatic in-transit melanoma. Proc Annu Meet Am Soc Clin Oncol 13: A1351
-
(1994)
Proc Annu Meet Am Soc Clin Oncol
, vol.13
-
-
Posner, M.1
Liénard, D.2
Lejeune, F.J.3
Rosenfelder, D.4
Kirkwood, J.5
-
29
-
-
0028232019
-
Early endothelium activation and polymorphonuclear cell invasion precede specific necrosis of human melanoma and sarcoma treated by intravascular high-dose tumour necrosis factor alpha (rTNFα)
-
Renard N, Liénard D, Lespagnard L, Eggermont A, Heimann R and Lejeune F (1994) Early endothelium activation and polymorphonuclear cell invasion precede specific necrosis of human melanoma and sarcoma treated by intravascular high-dose tumour necrosis factor alpha (rTNFα). Int J Cancer 57: 656-663
-
(1994)
Int J Cancer
, vol.57
, pp. 656-663
-
-
Renard, N.1
Liénard, D.2
Lespagnard, L.3
Eggermont, A.4
Heimann, R.5
Lejeune, F.6
-
30
-
-
0029144112
-
VWF release and platelet aggregation in human melanoma after perfusion with TNFα
-
Renard N, Nooijen PTGA, Schalkwijk L, de Waal RMW. Eggermont AMM, Liénard D, Kroon BBR, Lejeune FJ and Ruiter DJ (1995) VWF release and platelet aggregation in human melanoma after perfusion with TNFα. J Pathol 176: 279-287
-
(1995)
J Pathol
, vol.176
, pp. 279-287
-
-
Renard, N.1
Nooijen, P.T.G.A.2
Schalkwijk, L.3
De Waal, R.M.W.4
Eggermont, A.M.M.5
Liénard, D.6
Kroon, B.B.R.7
Lejeune, F.J.8
Ruiter, D.J.9
-
31
-
-
0028931781
-
Cytotoxic interactions of tumor necrosis factor, melphalan and 41.8°C hyperthermia
-
Robins HI, d'Oleire F, Kutz M, Bird A, Schmitt-Tiggelaar CL, Cohen JD and Spriggs DR (1995) Cytotoxic interactions of tumor necrosis factor, melphalan and 41.8°C hyperthermia. Cancer Lett 89: 55-62
-
(1995)
Cancer Lett
, vol.89
, pp. 55-62
-
-
Robins, H.I.1
D'Oleire, F.2
Kutz, M.3
Bird, A.4
Schmitt-Tiggelaar, C.L.5
Cohen, J.D.6
Spriggs, D.R.7
-
32
-
-
0024361443
-
Anti-tumor effect of recombinant TNF-alpha (rMuTNFα) given by continuous i.v. Infusion as compared to repeated i.v. Injections in a rat metastasis model
-
Scheringa M, Keizer A, Jeekel J and Marquet RL (1989) Anti-tumor effect of recombinant TNF-alpha (rMuTNFα) given by continuous i.v. infusion as compared to repeated i.v. injections in a rat metastasis model. Int J Cancer 43: 905-909
-
(1989)
Int J Cancer
, vol.43
, pp. 905-909
-
-
Scheringa, M.1
Keizer, A.2
Jeekel, J.3
Marquet, R.L.4
-
33
-
-
0026648398
-
The pharmacokinetic advantages of isolated limb perfusions with melphalan for malignant melanoma
-
Scott RN, Kerr DJ, Blackie R, Hughes J, Burnside G, Mackie RM, Byrne DS and McKay AJ (1992) The pharmacokinetic advantages of isolated limb perfusions with melphalan for malignant melanoma. Br J Cancer 66: 159-166
-
(1992)
Br J Cancer
, vol.66
, pp. 159-166
-
-
Scott, R.N.1
Kerr, D.J.2
Blackie, R.3
Hughes, J.4
Burnside, G.5
Mackie, R.M.6
Byrne, D.S.7
McKay, A.J.8
-
34
-
-
0029027185
-
The cytotoxicity of melphalan and its relationship to pH, hypoxia and drug uptake
-
Skarsgard LD, Skwarchuk MW, Vinezan A, Kristl J and Chaplin DJ (1995) The cytotoxicity of melphalan and its relationship to pH, hypoxia and drug uptake. Anticancer Res 15: 219-224
-
(1995)
Anticancer Res
, vol.15
, pp. 219-224
-
-
Skarsgard, L.D.1
Skwarchuk, M.W.2
Vinezan, A.3
Kristl, J.4
Chaplin, D.J.5
-
35
-
-
0026559430
-
Isolated limb perfusion for melanoma: Effectiveness and toxicity of cisplatin compared with that of melphalan and other drugs
-
Thompson JF and Gianoutsos MP (1992) Isolated limb perfusion for melanoma: effectiveness and toxicity of cisplatin compared with that of melphalan and other drugs. World J Surg 16: 227-233
-
(1992)
World J Surg
, vol.16
, pp. 227-233
-
-
Thompson, J.F.1
Gianoutsos, M.P.2
-
36
-
-
0028551932
-
Isolated limb infusion with melphalan for recurrent limb melanoma: A simple alternative to isolated limb perfusion
-
Thompson JF, Waugh RC, Saw RPM and Kam PCA (1994) Isolated limb infusion with melphalan for recurrent limb melanoma: a simple alternative to isolated limb perfusion. Reg Cancer Treat 7: 188-192
-
(1994)
Reg Cancer Treat
, vol.7
, pp. 188-192
-
-
Thompson, J.F.1
Waugh, R.C.2
Saw, R.P.M.3
Kam, P.C.A.4
-
37
-
-
0024408986
-
Blood flow, oxygen and nutrient supply, and metabolic micro environment of human tumors: A review
-
Vaupel P, Kallinowski F and Okunieff P (1989) Blood flow, oxygen and nutrient supply, and metabolic micro environment of human tumors: a review. Cancer Res 49: 6449-6465
-
(1989)
Cancer Res
, vol.49
, pp. 6449-6465
-
-
Vaupel, P.1
Kallinowski, F.2
Okunieff, P.3
-
38
-
-
4243779409
-
Absence of severe systemic toxicity after leakage controlled isolated limb perfusion (ILP) with high-dose TNFα and melphalan
-
Vrouenraets BC, Kroon BBR, Ogilvie AC, van Geel AN, Nieweg OE, Swaak AJG and Eggermont AMM (1997) Absence of severe systemic toxicity after leakage controlled isolated limb perfusion (ILP) with high-dose TNFα and melphalan. Melanoma Res 7: s111
-
(1997)
Melanoma Res
, vol.7
-
-
Vrouenraets, B.C.1
Kroon, B.B.R.2
Ogilvie, A.C.3
Van Geel, A.N.4
Nieweg, O.E.5
Swaak, A.J.G.6
Eggermont, A.M.M.7
-
39
-
-
0023832885
-
Synergistic cytotoxic and antitumor effects of recombinant human tumor necrosis factor and hyperthermia
-
Watanabe N, Niitsu Y, Umeno H, Sone H, Neda H, Yamauchi N, Maeda M and Urushizaki I (1988a) Synergistic cytotoxic and antitumor effects of recombinant human tumor necrosis factor and hyperthermia. Cancer Res 48: 650-653
-
(1988)
Cancer Res
, vol.48
, pp. 650-653
-
-
Watanabe, N.1
Niitsu, Y.2
Umeno, H.3
Sone, H.4
Neda, H.5
Yamauchi, N.6
Maeda, M.7
Urushizaki, I.8
-
40
-
-
0023877120
-
Toxic effect of tumor necrosis factor on tumor vasculature in mice
-
Watanabe N, Niitsu Y, Umeno H, Kuriyama H, Neda H, Yamauchi N, Maeda M and Urushizaki (1988b) Toxic effect of tumor necrosis factor on tumor vasculature in mice. Cancer Res 48: 2179-2183
-
(1988)
Cancer Res
, vol.48
, pp. 2179-2183
-
-
Watanabe, N.1
Niitsu, Y.2
Umeno, H.3
Kuriyama, H.4
Neda, H.5
Yamauchi, N.6
Maeda, M.7
Urushizaki8
-
41
-
-
0030975331
-
The effects of perfusion conditions on melphalan distribution in the isolated perfused rat hindlimb bearing a human melanoma xenograft
-
Wu ZY, Smithers BM, Parsons PG and Roberts MS (1997) The effects of perfusion conditions on melphalan distribution in the isolated perfused rat hindlimb bearing a human melanoma xenograft. Br J Cancer 75: 1160-1166
-
(1997)
Br J Cancer
, vol.75
, pp. 1160-1166
-
-
Wu, Z.Y.1
Smithers, B.M.2
Parsons, P.G.3
Roberts, M.S.4
|