Increase of the cytotoxic effect of Bothrops jararacussu venom on mouse extensor digitorum longus and soleus by potassium channel blockers and by Na+/K+-ATPase inhibition

Toxicon

Volumn 52, Issue 4, 2008, Pages 551-558

  Tomaz, Marcelo A ^a   Fernandes, Fabrício F A ^a   El Kik, Camila Z ^a   Moraes, Raphael A M ^a   Calil Elias, Sabrina ^b   Saturnino Oliveira, Jeison ^c   Martinez, Ana Maria B ^a   Ownby, Charlotte L ^d   Melo, Paulo A ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b Administracao Farmaceutica   (Brazil)

^c DEPARTAMENTO DE CIÊNCIAS BIOLÓGICAS   (Brazil)

^d OKLAHOMA STATE UNIVERSITY   (United States)

Author keywords

Bothrops jararacussu venom; Denervation; Mouse fast and slow twitch muscles; Myotoxicity; Potassium channels blockers

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); BATROXOBIN; BEE VENOM; CALCIUM; CLOTRIMAZOLE; CREATINE KINASE; GLIBENCLAMIDE; OUABAIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; SNAKE VENOM; TETRYLAMMONIUM; TRITON X 100;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME INHIBITION; ENZYME RELEASE; EXTENSOR DIGITORUM LONGUS MUSCLE; MOUSE; MUSCLE DENERVATION; NONHUMAN; PRIORITY JOURNAL; SOLEUS MUSCLE;

ANIMALS; BOTHROPS; CREATINE KINASE; CROTALID VENOMS; MICE; MUSCLE DENERVATION; MUSCLE, SKELETAL; OUABAIN; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; SODIUM-POTASSIUM-EXCHANGING ATPASE; TOXICITY TESTS;

AGKISTRODON CONTORTRIX LATICINCTUS; APIS MELLIFERA; BOTHROPS JARARACUSSU; CROTALUS DURISSUS TERRIFICUS; CROTALUS VIRIDIS VIRIDIS; NAJA NAJA; STROPHANTHUS GRATUS;

EID: 50949103700     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2008.07.003     Document Type: Article

References (50)

1. Albuquerque E.X., and McIsaac R.J. Fast and slow mammalian muscles after denervation. Exp. Biol. 26 (1969) 183-202
2. Calil-Elias S., Martinez A.M.B., and Melo P.A. Effect of heparin and antivenom on skeletal muscle damage produced by Bothrops jararacussu venom. Histol. Histopathol. 17 (2002) 463-470
3. + pump regulation and skeletal muscle contractility. Physiol. Rev. 83 (2003) 1269-1324
4. 2+ release and force development during fatigue in vitro. J. Physiol. 582 (2007) 843-857
5. da Silva N.M., Arruda E.Z., Murakami Y.L., Moraes R.A., El-Kik C.Z., Tomaz M.A., Fernandes F.F., Oliveira C.Z., Soares A.M., Giglio J.R., and Melo P.A. Evaluation of three Brazilian antivenom ability to antagonize myonecrosis and hemorrhage induced by Bothrops snake venoms in a mouse model. Toxicon 50 (2007) 196-205
6. Fatehi M., Harvey A.L., and Rowan E.G. Characterisation of the effects of depolarising toxins on nerve terminal action potentials: apparent block of presynaptic potassium currents. Toxicon 36 (1998) 115-129
7. Fuly A.L., Calil-Elias S., Martinez A.M., Melo P.A., and Guimarães J.A. Myotoxicity induced by an acidic Asp-49 phospholipase A(2) isolated from Lachesis muta snake venom. Comparison with lysophosphatidylcholine. Int. J. Biochem. Cell. Biol. 35 (2003) 1470-1481
8. 2: insights into mechanisms of local and systemic myotoxicity. Toxicon 42 (2003) 915-931
9. Gutiérrez J.M., Ownby C.L., and Odel G.V. Pathogenesis of myonecrosis induced by crude venom and a myotoxin of Bothrops asper. Exp. Mol. Pathol. 40 (1984) 367-379
10. Gutiérrez J.M., Rucavado A., Escalante T., and Diaz C. Hemorrhage induced by snake venom metalloproteinases: biochemical and biophysical mechanisms involved in microvessel damage. Toxicon 45 (2005) 997-1011
11. 2 and the regeneration of skeletal muscles. Toxicon 42 (2003) 933-945
12. Harris J.B., and Cullen M.J. Muscle necrosis caused by snake venoms and toxins. Electron. Microsc. Rev. 3 (1990) 183-211
13. Harris J.B., and Maltin C.A. Myotoxic activity of the crude venom and the principal neurotoxin, taipoxin, of the Australian taipan, Oxyuranus scutellatus. Br. J. Pharmacol. 76 (1982) 61-75
14. Harris J.B., Johnson M.A., and Karlsson E. Pathological responses of rat skeletal muscle to a single subcutaneous injection of a toxin isolated from the venom of the Australian tiger snake, Notechis scutatus scutatus. Clin. Exp. Pharmacol. Physiol. 2 (1975) 383-404
15. Harris J.B., Vater R., Wilson M., and Cullen M.J. Muscle fibre breakdown in venom-induced muscle degeneration. J. Anat. 202 (2003) 363-372
16. Harvey A.L. Snake venom peptides. In: Kastin A.J. (Ed). Handbook of Biologically Active Peptides (2006), Academic Press-Elsevier, USA 355-362
17. Hernandez-Benito M.J., Macianskiene R., Sipido K.R., Flameng W., and Mubagwa K. Suppression of transient outward potassium currents in mouse ventricular myocytes by imidazole antimycotics and by glybenclamide. J. Pharmacol. Exp. Ther. 298 (2001) 598-606
18. Hille B. Description of channels. Bertil Hille - Ion Channels of Excitable Membranes. third edition (2001), Sinauer Associates, Inc., MA, USA 23-306
19. Homsi-Brandeburgo M.I., Queiroz L.S., Santo-Neto H., Rodrigues-Simioni L., and Giglio J.R. Fractionation of Bothrops jararacussu snake venom: partial chemical characterization and biological activity of bothropstoxin. Toxicon 26 (1988) 615-627
20. Jenkinson D.H. Potassium channels - multiplicity and challenges. Br. J. Pharmacol. 147 (2006) S63-S71
21. Johnson E.K., and Ownby C.L. The role of extracellular ions in the pathogenesis of myonecrosis induced by a myotoxin isolated from Broad-Banded Copperhead (Agkistrodon contortrix laticinctus) venom. Comp. Biochem. Physiol. 107C 3 (1994) 359-366
22. 2 in rabbit skeletal muscle. FEBS 293 1, 2 (1991) 29-33
23. Leung W.N., Jeffrey P.I., and Rostas J.A. Effect of denervation on sarcolemmal proteins and glycoproteins of fast and slow mammalian skeletal muscle. Exp. Neurol. 91 (1986) 229-245
24. Lin Y.L., Lin S.R., Wu T.T., and Chang L.S. Evidence showing an intermolecular interaction between KChIP proteins and Taiwan cobra cardiotoxins. Biochem. Biophys. Res. Commun. 319 (2004) 720-724
25. Magnusson C., Hogklint L., Libelius R., and Tagerud S. Expression of mRNA for plasminogen activators and protease nexin-1 in innervated and denervated mouse skeletal muscle. J. Neurosci. Res. 66 (2001) 457-463
26. Mazzi M.V., Marcussi S., Carlos G.B., Stábeli R.G., Franco J.J., Ticli F.K., Cintra A.C., França S.C., Soares A.M., and Sampaio S.V. A new hemorrhagic metalloprotease from Bothrops jararacussu snake venom: isolation and biochemical characterization. Toxicon 44 (2004) 215-223
27. Mebs D., and Ownby C.L. Myotoxic components of snake venoms: their biochemical and biological activities. Pharmacol. Ther. 48 (1990) 223-236
28. Melo P.A., and Ownby C.L. Different sensitivity of fast- and slow-twitch muscles to some snake venoms and myotoxins. Toxicon 34 (1996) 653-669
29. 2 myotoxins. Toxicon 37 (1999) 199-215
30. Melo P.A., and Suarez-Kurtz G. Release of creatine kinase from skeletal muscle by Bothrops venoms: heparin potentiation of inhibition by antivenin. Braz. J. Med. Biol. Res. 21 (1988) 545-548
31. Melo P.A., and Suarez-Kurtz G. Release of sarcoplasmic enzymes from skeletal muscle by Bothrops jararacussu venom: antagonism by heparin and by the serum of South American marsupials. Toxicon 26 (1988) 87-95
32. Melo P.A., Homsi-Brandeburgo M.I., Giglio J.R., and Suarez-Kurtz G. Antagonism of the myotoxic effects of Bothrops jararacussu venom and bothropstoxin by polyanions. Toxicon 31 (1993) 285-291
33. Melo P.A., Nascimento M.C., Mors W.B., and Suarez-Kurtz G. Inhibition of the myotoxic and hemorrhagic activities of crotalid venoms by Eclipta prostrata (Asteraceae) extracts and constituents. Toxicon 32 (1994) 595-603
34. Melo P.A., Burns C.F., Blankemeyer J.T., and Ownby C.L. Membrane depolarization is the initial action of crotoxin on isolated murine skeletal muscle. Toxicon 43 (2004) 111-119
35. + channel density in extrajunctional sarcolemma of fast and slow twitch mouse skeletal muscle fibers: functional implications and plasticity after fast motoneuron transplantation on to a slow muscle. J. Muscle Res. Cell Motil. 16 (1995) 430-439
36. Mora R., Maldonado A., Valverde B., and Gutiérrez J.M. Calcium plays a key role in the effects induced by a snake venom Lys49 phospholipase A2 homologue on a lymphoblastoid cell line. Toxicon 47 (2006) 75-86
37. + shifts induced by contractile activities of rat skeletal muscles. Comp. Biochem. Physiol. A Physiol. 109 (1994) 957-965
38. Neelands T.R., Herson P.S., Jacobson D., Adelman J.P., and Maylie J. Small-conductance calcium-activated potassium currents in mouse hyperexcitable denervated skeletal muscle. J. Physiol. 536.2 (2001) 397-407
39. Okamoto T., IsodaKubota H.N., Takahata K., Takahashi T., KishiNakamura T.Y., Muromachi Y., Matsui Y., and Goshima K. Melittin cardiotoxicity in cultured mouse cardiac myocytes and its correlation with calcium overload. Toxicol. Appl. Pharmacol. 133 (1995) 150-163
40. Ownby C.L., and Colberg T.R. Classification of myonecrosis induced by snake venoms: venoms from the prairie rattlesnake (Crotalus viridis viridis), western diamondback rattlesnake (Crotalus atrox) and the indian cobra (Naja naja naja). Toxicon 26 (1988) 459-474
41. Ownby C.L., Cameron D., and Tu A.T. Isolation of myotoxic component from rattlesnake (Crotalus viridis viridis) venom. Electron microscopic analysis of muscle damage. Am. J. Pathol. 85 (1976) 149-166
42. 2 from bee (Apis mellifera) venom cause necrosis of murine skeletal muscle in vivo. Toxicon 33 (1997) 67-80
43. Pang Y., Hunton D.L., Bounelis P., and Marchase R.B. Hyperglycemia inhibits capacitative calcium entry and hypertrophy in neonatal cardiomyocytes. Diabetes 51 (2002) 3461-3467
44. Panunto P.C., Da Silva M.A., Linardi A., Buzin M.P., Melo S.E., Mello S.M., Prado-Franceschi J., and Hyslop S. Biological activities of a lectin from Bothrops jararacussu snake venom. Toxicon 47 (2006) 21-31
45. Perez A.V., Saravia P., Rucavado A., Sant'ana C.D., Soares A.M., and Gutiérrez J.M. Local and systemic pathophysiological alterations induced by a serine proteinase from the venom of the snake Bothrops jararacussu. Toxicon 49 (2007) 1063-1069
46. Queiroz L.S., Santo-Neto H., Rodriques-Simioni L., and Prado-Franceschi J. Muscle necrosis and regeneration after envenomation by Bothrops jararacussu snake venom. Toxicon 22 (1984) 339-346
47. Queiroz L.S., Marques M.J., and Santo Neto H. Acute local nerve lesions induced by Bothrops jararacussu snake venom. Toxicon 40 (2002) 1483-1486
48. Rosenfeld G. Symptomatology, pathology and treatment of snake bites in South America. Venomous Animals and their Venoms vol. 2 (1971), Academic Press, New York, 345-384
49. 2 variant: isolation and characterization from eastern regional Indian cobra (Naja naja) venom. Toxicon 47 (2006) 727-733
50. Villalobos J.C., Mora R., Lomonte B., Gutiérrez J.M., and Angulo Y. Cytotoxicity induced in myotubes by a Lys49 phospholipase A2 homologue from the venom of the snake Bothrops asper: evidence of rapid plasma membrane damage and a dual role for extracellular calcium. Toxicol. In Vitro 21 (2007) 1382-1389