Enhanced in vivo transgene expression and immunogenicity from plasmid vectors following electrostimulation in rodents and primates

Vaccine

Volumn 26, Issue 40, 2008, Pages 5202-5209

  Simon, Adam J ^a   Casimiro, Danilo R ^a   Finnefrock, Adam C ^a   Davies, Mary Ellen ^a   Tang, Aimin ^a   Chen, Minchun ^a   Chastain, Michael ^a   Kath, Gary S ^a   Chen, Ling ^a   Shiver, John W ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

DNA vaccines; Electroporation

Indexed keywords

DNA VACCINE; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; PLASMID VECTOR;

ADENOVIRUS 5; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BAGG ALBINO MOUSE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG POTENCY; ELECTROPORATION; ELECTROSTIMULATION; FEMALE; GENE EXPRESSION; IMMUNOGENICITY; IN VIVO STUDY; MACACA; MOUSE; NONHUMAN; PRIMATE; PRIORITY JOURNAL; RODENT; TRANSGENE;

AIDS VACCINES; ALKALINE PHOSPHATASE; ANIMALS; CELL LINE; ELECTROPORATION; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HIV INFECTIONS; HUMANS; MACACA; MICE; MICE, INBRED BALB C; PLASMIDS; TRANSGENES; VACCINES, DNA;

EID: 50849125106     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2008.03.058     Document Type: Article

References (51)

1. Robbins P.D., Tahara H., and Ghivizzani S.C. Viral vectors for gene therapy. Trends Biotechnol 16 January (1) (1998) 35-40
2. Wolff J.A., Malone R.W., Williams P., Chong W., Acsadi G., Jani A., et al. Direct gene transfer into mouse muscle in vivo. Science 247 March (4949 Pt 1) (1990) 1465-1468
3. Yang N.S., Burkholder J., Roberts B., Martinell B., and McCabe D. In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment. Proc Natl Acad Sci USA 87 December (24) (1990) 9568-9572
4. Vahlsing H.L., Yankauckas M.A., Sawdey M., Gromkowski S.H., and Manthorpe M. Immunization with plasmid DNA using a pneumatic gun. J Immunol Methods 175 September (1) (1994) 11-22
5. Fynan E.F., Webster R.G., Fuller D.H., Haynes J.R., Santoro J.C., and Robinson H.L. DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations. Proc Natl Acad Sci USA 90 December (24) (1993) 11478-11482
6. Furth P.A., Shamay A., and Hennighausen L. Gene transfer into mammalian cells by jet injection. Hybridoma 14 April (2) (1995) 149-152
7. Nishikawa M., and Huang L. Nonviral vectors in the new millennium: delivery barriers in gene transfer. Hum Gene Ther 12 May (8) (2001) 861-870
8. Tripathy S.K., Svensson E.C., Black H.B., Goldwasser E., Margalith M., Hobart P.M., et al. Long-term expression of erythropoietin in the systemic circulation of mice after intramuscular injection of a plasmid DNA vector. Proc Natl Acad Sci USA 93 October (20) (1996) 10876-10880
9. Ulmer J.B., Donnelly J.J., Parker S.E., Rhodes G.H., Felgner P.L., Dwarki V.J., et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 259 March (5102) (1993) 1745-1749
10. Davis H.L., Michel M.L., and Whalen R.G. DNA-based immunization induces continuous secretion of hepatitis B surface antigen and high levels of circulating antibody. Hum Mol Genet 2 November (11) (1993) 1847-1851
11. Donnelly J.J., Ulmer J.B., Shiver J.W., and Liu M.A. DNA vaccines. Annu Rev Immunol 15 (1997) 617-648
12. Iwasaki A., Stiernholm B.J., Chan A.K., Berinstein N.L., and Barber B.H. Enhanced CTL responses mediated by plasmid DNA immunogens encoding costimulatory molecules and cytokines. J Immunol 158 May (10) (1997) 4591-4601
13. Krieg A.M. The role of CpG motifs in innate immunity. Curr Opin Immunol 12 February (1) (2000) 35-43
14. Luo Y., O'Hagan D., Zhou H., Singh M., Ulmer J., Reisfeld R.A., et al. Plasmid DNA encoding human carcinoembryonic antigen (CEA) adsorbed onto cationic microparticles induces protective immunity against colon cancer in CEA-transgenic mice. Vaccine 21 May (17/18) (2003) 1938-1947
15. Titomirov A.V., Sukharev S., and Kistanova E. In vivo electroporation and stable transformation of skin cells of newborn mice by plasmid DNA. Biochim Biophys Acta 1088 January (1) (1991) 131-134
16. Heller R., Jaroszeski M., Atkin A., Moradpour D., Gilbert R., Wands J., et al. In vivo gene electroinjection and expression in rat liver. FEBS Lett 389 July (3) (1996) 225-228
17. Nishi T., Yoshizato K., Yamashiro S., Takeshima H., Sato K., Hamada K., et al. High-efficiency in vivo gene transfer using intraarterial plasmid DNA injection following in vivo electroporation. Cancer Res 56 March (5) (1996) 1050-1055
18. Rols M.P., Delteil C., Golzio M., Dumond P., Cros S., and Teissie J. In vivo electrically mediated protein and gene transfer in murine melanoma. Nat Biotechnol 16 February (2) (1998) 168-171
19. Muramatsu T., Mizutani Y., Ohmori Y., and Okumura J. Comparison of three nonviral transfection methods for foreign gene expression in early chicken embryos in ovo. Biochem Biophys Res Commun 230 January (2) (1997) 376-380
20. Aihara H., and Miyazaki J. Gene transfer into muscle by electroporation in vivo. Nat Biotechnol 16 September (9) (1998) 867-870
21. Mir L.M., Bureau M.F., Rangara R., Schwartz B., and Scherman D. Long-term, high level in vivo gene expression after electric pulse-mediated gene transfer into skeletal muscle. C R Acad Sci III 321 November (11) (1998) 893-899
22. Mir L.M., Bureau M.F., Gehl J., Rangara R., Rouy D., Caillaud J.M., et al. High-efficiency gene transfer into skeletal muscle mediated by electric pulses. Proc Natl Acad Sci USA 96 April (8) (1999) 4262-4267
23. Vicat J.M., Boisseau S., Jourdes P., Laine M., Wion D., Bouali-Benazzouz R., et al. Muscle transfection by electroporation with high-voltage and short-pulse currents provides high-level and long-lasting gene expression. Hum Gene Ther 11 April (6) (2000) 909-916
24. Selby M., Goldbeck C., Pertile T., Walsh R., and Ulmer J. Enhancement of DNA vaccine potency by electroporation in vivo. J Biotechnol 83 September (1/2) (2000) 147-152
25. Widera G., Austin M., Rabussay D., Goldbeck C., Barnett S.W., Chen M., et al. Increased DNA vaccine delivery and immunogenicity by electroporation in vivo. J Immunol 164 May (9) (2000) 4635-4640
26. Dupuis M., Denis-Mize K., Woo C., Goldbeck C., Selby M.J., Chen M., et al. Distribution of DNA vaccines determines their immunogenicity after intramuscular injection in mice. J Immunol 165 September (5) (2000) 2850-2858
27. Banga A.K., and Prausnitz M.R. Assessing the potential of skin electroporation for the delivery of protein- and gene-based drugs. Trends Biotechnol 16 October (10) (1998) 408-412
28. Belehradek M., Domenge C., Luboinski B., Orlowski S., Belehradek Jr. J., and Mir L.M. Electrochemotherapy, a new antitumor treatment. First clinical phase I-II trial. Cancer 72 December (12) (1993) 3694-3700
29. Hofmann G.A., Dev S.B., Nanda G.S., and Rabussay D. Electroporation therapy of solid tumors. Crit Rev Ther Drug Carrier Syst 16 6 (1999) 523-569
30. Hofmann G.A., Dev S.B., Dimmer S., and Nanda G.S. Electroporation therapy: a new approach for the treatment of head and neck cancer. IEEE Trans Biomed Eng 46 June (6) (1999) 752-759
31. Goto T., Nishi T., Tamura T., Dev S.B., Takeshima H., Kochi M., et al. Highly efficient electro-gene therapy of solid tumor by using an expression plasmid for the herpes simplex virus thymidine kinase gene. Proc Natl Acad Sci USA 97 January (1) (2000) 354-359
32. Mathiesen I. Electropermeabilization of skeletal muscle enhances gene transfer in vivo. Gene Ther 6 April (4) (1999) 508-514
33. Rizzuto G., Cappelletti M., Maione D., Savino R., Lazzaro D., Costa P., et al. Efficient and regulated erythropoietin production by naked DNA injection and muscle electroporation. Proc Natl Acad Sci USA 96 May (11) (1999) 6417-6422
34. Rizzuto G., Cappelletti M., Mennuni C., Wiznerowicz M., DeMartis A., Maione D., et al. Gene electrotransfer results in a high-level transduction of rat skeletal muscle and corrects anemia of renal failure. Hum Gene Ther 11 September (13) (2000) 1891-1900
35. Cappelletti M., Zampaglione I., Rizzuto G., Ciliberto G., La Monica N., and Fattori E. Gene electro-transfer improves transduction by modifying the fate of intramuscular DNA. J Gene Med 5 April (4) (2003) 324-332
36. Lamartina S., Silvi L., Roscilli G., Casimiro D., Simon A.J., Davies M.E., et al. Construction of an rtTA2 (s)-m2/tts (kid)-based transcription regulatory switch that displays no basal activity, good inducibility, and high responsiveness to doxycycline in mice and non-human primates. Mol Ther 7 February (2) (2003) 271-280
37. Mennuni C., Calvaruso F., Zampaglione I., Rizzuto G., Rinaudo D., Dammassa E., et al. Hyaluronidase increases electrogene transfer efficiency in skeletal muscle. Hum Gene Ther 13 February (3) (2002) 355-365
38. Zucchelli S., Capone S., Fattori E., Folgori A., Di Marco A., Casimiro D., et al. Enhancing B- and T-cell immune response to a hepatitis C virus E2 DNA vaccine by intramuscular electrical gene transfer. J Virol 74 December (24) (2000) 11598-11607
39. Chastain M., Simon A.J., Soper K.A., Holder D.J., Montgomery D.L., Sagar S.L., et al. Antigen levels and antibody titers after DNA vaccination. J Pharm Sci 90 April (4) (2001) 474-484
40. Casimiro D.R., Tang A., Perry H.C., Long R.S., Chen M., Heidecker G.J., et al. Vaccine-induced immune responses in rodents and nonhuman primates by use of a humanized human immunodeficiency virus type 1 pol gene. J Virol 76 January (1) (2002) 185-194
41. Graham F.L. Adenoviruses as expression vectors and recombinant vaccines. Trends Biotechnol 8 April (4) (1990) 85-87
42. Lathe R. Synthetic oligonucleotide probes deduced from amino acid sequence data. Theoretical and practical considerations. J Mol Biol 183 May (1) (1985) 1-12
43. Dubey S., Clair J., Fu T.M., Guan L., Long R., Mogg R., et al. Detection of HIV vaccine-induced cell-mediated immunity in HIV-seronegative clinical trial participants using an optimized and validated enzyme-linked immunospot assay. J Acquir Immune Defic Syndr 45 May (1) (2007) 20-27 PMID: 17310936
44. Shiver J.W., Perry H.C., Davies M.E., and Liu M.A. Immune responses to HIV gp120 elicited by DNA vaccination. In: Chanock R.M., Brown F., Ginsberg H.S., and Norrby E. (Eds). Vaccines 95 (1995), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY 95-98
45. Capone S., Zampaglione I., Vitelli A., Pezzanera M., Kierstead L., Burns J., et al. Modulation of the immune response induced by gene electrotransfer of a hepatitis C virus DNA vaccine in nonhuman primates. J Immunol 177 November (10) (2006) 7462-7471
46. Zampaglione I., Arcuri M., Cappelletti M., Ciliberto G., Perretta G., Nicosia A., et al. In vivo DNA gene electro-transfer: a systematic analysis of different electrical parameters. J Gene Med 7 November (11) (2005) 1475-1481
47. Fattori E., Cappelletti M., Zampaglione I., Mennuni C., Calvaruso F., Arcuri M., et al. Gene electro-transfer of an improved erythropoietin plasmid in mice and non-human primates. J Gene Med 7 February (2) (2005) 228-236
48. Koup R.A., Safrit J.T., Cao Y., Andrews C.A., McLeod G., Borkowsky W., et al. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J Virol 68 July (7) (1994) 4650-4655
49. Shiver J.W., Fu T.M., Chen L., Casimiro D.R., Davies M.E., Evans R.K., et al. Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity. Nature 415 January (6869) (2002) 331-335
50. Zampaglione I., Simon A.J., Capone S., Finnefrock A.C., Casimiro D.R., Kath G.S., et al. Genetic vaccination by gene electro-transfer in non-human primates. J Drug Deliv Sci Technol 16 January/February (1) (2006) 85-89
51. Ugen K.E., Kutzler M.A., Marrero B., Westover J., Coppola D., Weiner D.B., et al. Regression of subcutaneous B16 melanoma tumors after intratumoral delivery of an IL-15-expressing plasmid followed by in vivo electroporation. Cancer Gene Ther 13 October (10) (2006) 969-974