Electron Capture Dissociation, Electron Detachment Dissociation, and Collision-Induced Dissociation of Polyamidoamine (PAMAM) Dendrimer Ions with Amino, Amidoethanol, and Sodium Carboxylate Surface Groups

Journal of the American Society for Mass Spectrometry

Volumn 19, Issue 9, 2008, Pages 1312-1319

  Kaczorowska, Malgorzata A ^a   Cooper, Helen J ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; CARBOXYLATION; CHLORINE COMPOUNDS; DENDRIMERS; ELECTROCHEMICAL SENSORS; ELECTROCHROMIC DEVICES; ELECTRONS; ELECTROOPTICAL DEVICES; MASS SPECTROMETERS; MASS SPECTROMETRY; REDUCTION; STRUCTURAL ANALYSIS;

COLLISION-INDUCED DISSOCIATION; ELECTRON CAPTURE DISSOCIATION; ELECTRON DETACHMENT DISSOCIATION; MASS SPECTRUM; PAMAM DENDRIMERS; POLYAMIDOAMINE DENDRIMER; POLYAMIDOAMINE DENDRIMERS; SODIUM CARBOXYLATES; SURFACE GROUPS;

DISSOCIATION;

AMINE; CARBOXYLIC ACID; DENDRIMER; POLYAMIDOAMINE; SODIUM CARBOXYLIC ACID; UNCLASSIFIED DRUG;

ARTICLE; COLLISIONALLY ACTIVATED DISSOCIATION; ELECTRON CAPTURE DETECTION;

AMINES; CARBOXYLIC ACIDS; ELECTRONS; ETHANOL; IONS; POLYAMINES; SODIUM COMPOUNDS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SURFACE PROPERTIES;

EID: 50849123732     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2008.06.016     Document Type: Article

References (21)

1. Tomalia D. A., Kaplan D. A., Kruper W. J. Jr., Cheng R. C., Tomplinson I. A., Fazio M. J., Edwards D. S. U.S. Patent 5 728 461, 1994.
2. Tomalia D.A., Baker H., Dewald J., Hall M., Kallos G., Martin S., Roeck J., Ryder J., and Smith P. A New Class of Polymers: Starburst Dendritic Macromolecules. Polym. J 17 (1985) 117-132
3. Tomalia D.A., and Esfand R. Dendrons, Dendrimers and Dendigrafts. Chem. Ind 11 (1997) 416-420
4. Esfand R., and Tomalia D.A. Poly(amidoamine) (PAMAM) Dendrimers: From Biomimicry to Drug Delivery and Biomedical Applications. Drug Disc. Today 6 (2001) 427-436
5. Boas U., and Heegaard P.M.H. Dendrimers in Drug Research. Chem. Soc. Rev 33 (2004) 43-63
6. Svenson S., and Tomalia D.A. Commentary: Dendrimers in Biomedical Applications-Reflections on the Field. Adv. Drug Del. Rev 57 (2005) 2106-2129
7. Tomalia D.A., Reyna L.A., and Svenson S. Dendrimers as Multi-Purpose Nanodevices for Oncology Drug Delivery and Diagnostic Imaging. Biochem. Soc. Trans 35 (2007) 61-67
8. Caminade A.-M., Laurent R., and Majoral J.-P. Characterization of Dendrimers. Adv. Drug Del. Rev 57 (2005) 2130-2146
9. Pasa-Tolic L., Anderson G.A., Smith R.D., Brothers H.M., Spindler R., and Tomalia D.A. ESI FT-ICR Mass Spectrometric Characterization of High Molecular Mass Starburst Dendrimers. Int. J. Mass Spectrom 165 (1997) 405-418
10. Muller R., Laschober C., Szymanski W.W., and Allmaier G. Determination of Molecular Weight, Particle Size, and Density of High Number Generation PAMAM Dendrimers Using MALDI-TOF-MS and nES-GEMMA. Macromolecules 40 (2007) 5599-5605
11. 2+ by MALDI Mass Spectrometry. Macromolecules 34 (2001) 3567-3573
12. Giordanengo R., Mazarin M., Wu J., Peng L., and Charles L. Propagation of Structural Deviations of PAMAM Fan-Shape Dendrimers (Generations 0-3) Characterized by MALDI and Electrospray Mass Spectrometry. Int. J. Mass Spectrom 266 (2007) 62-75
13. Peterson J., Allikmaa V., Subbi J., Pehk T., and Lopp M. Structural Deviations in PAMAM Dendrimers: A MALDI-TOF-MS Analysis. Eur. Polym. J 39 (2003) 33-42
14. Subbi J., Aguraiuja R., Tanner R., Allikmaa V., and Lopp M. Fragmentation of PAMAM Dendrimers in MALDI. Eur. Polym. J 41 (2005) 2552-2558
15. Mazzitelli C.L., and Brodbelt J.S. Investigation of Silver-Binding to PAMAM Dendrimers by ESI Tandem Mass Spectrometry. J. Am. Soc. Mass Spectrom 17 (2006) 676-684
16. He M., and McLuckey S.A. Tandem Mass Spectrometry of Half Generation PAMAM Dendrimer Anions. Rapid Commun. Mass Spectrom 18 (2004) 960-972
17. Lee S., Han S.Y., Lee T.G., Chung G., Lee D., and Oh H.B. Observation of Pronounced b-Dot, y Cleavages in the ECD Mass Spectrometry of PAMAM Dendrimer Ions with Amide Functionalities. J. Am. Soc. Mass Spectrom 17 (2006) 536-543
18. Zubarev R.A., Kelleher N.L., and McLafferty F.W. ECD of Multiply Charged Protein Cations. A Non-Ergodic Process. J. Am. Chem. Soc 120 (1998) 3265-3266
19. Budnik B.A., Haselmann K.F., and Zubarev R.A. Electron Detachment Dissociation of Peptide Di-Anions: An Electron-Hole Recombination Phenomenon. Chem. Phys. Lett 342 (2001) 299-302
20. Crooks R.M., Lemon B.I., Sun L., Yeung L.K., and Zhao M.Q. Dendrimer Encapsulated Metals and Semiconductors: Synthesis, Characterization, and Applications. In: Vogtle F. (Ed). Dendrimers III: Design, Dimension, Function (2001), Springer-Verlag, Berlin 81-135
21. Neta P., Pu Q.-L., Kilpatrick L., Yang X., and Stein S.E. Dehydration versus Deamination of N-Terminal Glutamine in CID of Protonated Peptides. J. Am. Soc. Mass Spectrom 18 (2006) 27-36