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Volumn 84, Issue 3, 2008, Pages 651-

The potential role of Nutlins in the treatment of B-chronic lymphocytic leukemia (B-CLL)

Author keywords

Apoptosis; Cell cycle progression; CpG oligodeoxynucleotides; MDM2 inhibitor

Indexed keywords

ANTINEOPLASTIC AGENT; NUTLIN; OLIGODEOXYNUCLEOTIDE; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 50849103036     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0408222     Document Type: Letter
Times cited : (4)

References (10)
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    • Combined treatment of CpG-oligodeoxynucleotide with Nutlin-3 induces strong immune stimulation coupled to cytotoxicity in B-chronic lymphocytic leukemic (B-CLL) cells
    • Secchiero, P., Melloni, E., Tiribelli, M., Gonelli, A., Zauli, G. (2008) Combined treatment of CpG-oligodeoxynucleotide with Nutlin-3 induces strong immune stimulation coupled to cytotoxicity in B-chronic lymphocytic leukemic (B-CLL) cells. J. Leukoc. Biol. 83, 434-437.
    • (2008) J. Leukoc. Biol , vol.83 , pp. 434-437
    • Secchiero, P.1    Melloni, E.2    Tiribelli, M.3    Gonelli, A.4    Zauli, G.5
  • 2
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    • Comprehensive biomarker and genomic analysis identifies p53 status as the major determinant of response to MDM2 inhibitors in chronic lymphocytic leukemia
    • Saddler, C., Ouillette, P., Kujawski, L., Shangary, S., Talpaz, M., Kaminski, M., Erba, H., Shedden, K., Wang, S., Malek, S. N. (2008) Comprehensive biomarker and genomic analysis identifies p53 status as the major determinant of response to MDM2 inhibitors in chronic lymphocytic leukemia. Blood 111, 1584-1593.
    • (2008) Blood , vol.111 , pp. 1584-1593
    • Saddler, C.1    Ouillette, P.2    Kujawski, L.3    Shangary, S.4    Talpaz, M.5    Kaminski, M.6    Erba, H.7    Shedden, K.8    Wang, S.9    Malek, S.N.10
  • 5
    • 33746646758 scopus 로고    scopus 로고
    • Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukemia
    • Kojima, K., Konopleva, M., McQueen, T., O'Brien, S., Plunkett, W., Andreeff, M. (2006) Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukemia. Blood 108, 993-1000.
    • (2006) Blood , vol.108 , pp. 993-1000
    • Kojima, K.1    Konopleva, M.2    McQueen, T.3    O'Brien, S.4    Plunkett, W.5    Andreeff, M.6
  • 6
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    • Good prognosis cytogenetics in B-cell chronic lymphocytic leukemia is associated in vitro with low susceptibility to apoptosis and enhanced immunogenicity
    • Jahrsdörfer, B., Wooldridge, J. E., Blackwell, S. E., Taylor, C. M., Link, B. K., Weiner, G. J. (2005) Good prognosis cytogenetics in B-cell chronic lymphocytic leukemia is associated in vitro with low susceptibility to apoptosis and enhanced immunogenicity. Leukemia 19, 759-766.
    • (2005) Leukemia , vol.19 , pp. 759-766
    • Jahrsdörfer, B.1    Wooldridge, J.E.2    Blackwell, S.E.3    Taylor, C.M.4    Link, B.K.5    Weiner, G.J.6
  • 8
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    • The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease
    • Longo, P. G., Laurenti, L., Gobessi, S., Petlickovski, A., Pelosi, M., Chiusolo, P., Sica, S., Leone, G., Efremov, D. G. (2007) The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease. Leukemia 21, 110-120.
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    • Longo, P.G.1    Laurenti, L.2    Gobessi, S.3    Petlickovski, A.4    Pelosi, M.5    Chiusolo, P.6    Sica, S.7    Leone, G.8    Efremov, D.G.9
  • 10
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    • Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: An updated retrospective comparative analysis of CALGB 9712 and CALGB 9011
    • Byrd, J. C., Rai, K., Peterson, B. L., Appelbaum, F. R., Morrison, V. A., Kolitz, J. E., Shepherd, L., Hines, J. D., Schiffer, C. A., Larson, R. A. (2005) Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: an updated retrospective comparative analysis of CALGB 9712 and CALGB 9011. Blood 105, 49-53.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.