Relaxing effect and mechanism of tafluprost on isolated rabbit ciliary arteries

Experimental Eye Research

Volumn 87, Issue 3, 2008, Pages 251-256

  Dong, Yaru ^a,b   Watabe, Hiroshi ^a   Su, Guanfang ^b   Ishikawa, Hitoshi ^c   Sato, Noriko ^a   Yoshitomi, Takeshi ^a  

^a AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b JILIN UNIVERSITY   (China)

^c KITASATO UNIVERSITY   (Japan)

Author keywords

Ca2+; glaucoma; tafluprost; vasodilator

Indexed keywords

DILTIAZEM; HISTAMINE; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; OUABAIN; POTASSIUM; TAFLUPROST; THAPSIGARGIN;

ANIMAL EXPERIMENT; ARTICLE; CILIARY ARTERY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; MALE; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PHOTOMETRY; PRIORITY JOURNAL; SMOOTH MUSCLE;

ANIMALS; CALCIUM; CILIARY ARTERIES; DILTIAZEM; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTAMINE; PROSTAGLANDINS F; RABBITS; TISSUE CULTURE TECHNIQUES; VASODILATION; VASODILATOR AGENTS;

EID: 50849096378     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2008.06.005     Document Type: Article

References (33)

1. Akaishi T., Kurashima H., Odani N., Ishida N., and Shimazaki A. Comparison of the effect of tafluprost, latanoprost and travoprost on the optic nerve head blood flow in rabbits. Invest. Ophthalmol. Vis. Sci. 48 (2007) (E-abstract 2278)
2. Dong Y., Ishikawa H., Wu Y., Shimizu K., Goseki T., and Yoshitomi T. Effect and mechanisms of betaxolol and timolol on vascular relaxation in isolated rabbit ciliary artery. Jpn. J. Ophthalmol. 50 (2006) 504-508
3. Dong Y., Ishikawa H., Wu Y., and Yoshitomi T. Vasodilatory mechanism of levobunolol on vascular smooth muscle cells. Exp. Eye Res. 84 (2007) 1039-1046
4. Flammer J., Orgul S., Costa V.P., Orzalesi N., Krieglstein G.K., Serra L.M., Renard J.P., and Stefansson E. The impact of ocular blood flow in glaucoma. Prog. Retin. Eye Res. 21 (2002) 359-393
5. Gunthorpe M.J., and Lummis S.C. Diltiazem causes open channel block of recombinant 5-HT3 receptors. J. Physiol. 519 (1999) 713-722
6. Halpern W., Mulvany M.J., and Warshaw D.M. Mechanical properties of smooth muscle cells in the walls of arterial resistance vessels. J. Physiol. 275 (1978) 85-101
7. Hayashi-Morimoto R., Yoshitomi T., Ishikawa H., Hayashi E., and Sato Y. Effects of beta antagonists on mechanical properties in rabbit ciliary artery. Graefes Arch. Clin. Exp. Ophthalmol. 237 (1999) 661-667
8. Hutchinson P.J., Palmer R.M., and Moncada S. Comparative pharmacology of EDRF and nitric oxide on vascular strips. Eur. J. Pharmacol. 141 (1987) 445-451
9. Ishii K., Tomidokoro A., Nagahara M., Tamaki Y., Kanno M., Fukaya Y., and Araie M. Effects of topical latanoprost on optic nerve head circulation in rabbits, monkeys, and humans. Invest. Ophthalmol. Vis. Sci. 42 (2001) 2957-2963
10. 2α on isolated rabbit ciliary artery. Graefes Arch. Clin. Exp. Ophthalmol. 240 (2002) 120-125
11. Kashiwagi K., Iizuka Y., and Tsukahara S. Metabolites of isopropyl unoprostone as potential ophthalmic solutions to reduce intraocular pressure in pigmented rabbits. Jpn. J. Pharmacol. 81 (1999) 56-62
12. Katz A.M. Molecular biology of calcium channels in the cardiovascular system. Am. J. Cardiol. 80 (1997) 171-221
13. Keef K.D., and Bowen S.M. Effect of ACh on electrical and mechanical activity in guinea pig coronary arteries. Am. J. Physiol. 257 (1989) H1096-H1103
14. Komori K., and Vanhoutte P.M. Endothelium-derived hyperpolarizing factor. Blood Vessels 27 (1990) 238-245
15. Laporte R., and Laher I. Sarcoplasmic reticulum-sarcolemma interactions and vascular smooth muscle tone. J. Vasc. Res. 34 (1997) 325-343
16. Mulvany M.J., and Halpern W. Mechanical properties of vascular smooth muscle cells in situ. Nature. 260 (1976) 617-619
17. Mulvany M.J., and Halpern W. Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. Circ. Res. 41 (1977) 19-26
18. 2αderivatives with prostanoid FP-receptor agonistic activity as potent ocular-hypotensive agents. Biol. Pharm. Bull. 26 (2003) 1691-1695
19. Numaga J., Koseki N., Kaburaki T., Kawashima H., Tomita G., and Araie M. Intraocular metabolites of isopropyl unoprostone. Curr. Eye Res. 30 (2005) 909-913
20. Ota T., Murata H., Sugimoto E., Aihara M., and Araie M. Prostaglandin analogues and mouse intraocular pressure: Effects of tafluprost, latanoprost, travoprost, and unoprostone considering 24-hour variation. Invest. Ophthalmol. Vis. Sci. 46 (2005) 2006-2011
21. Palmer R.M., Rees D.D., Ashton D.S., and Moncada S. l-Arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation. Biochem. Biophys. Res. Commun. 153 (1988) 1251-1256
22. Potocnik S.J., and Hill M.A. Pharmacological evidence for capacitative Ca(2+) entry in cannulated and pressurized skeletal muscle arterioles. Br. J. Pharmacol. 134 (2001) 247-256
23. Putney Jr. J.W. A model for receptor-regulated calcium entry. Cell Calcium. 7 (1986) 1-12
24. Putney Jr. J.W. Capacitative calcium entry revisited. Cell Calcium. 11 (1990) 611-624
25. Putney Jr. J.W., and Bird G.S. The signal for capacitative calcium entry. Cell. 75 (1993) 199-201
26. Putney Jr. J.W., and Bird G.S. Calcium mobilization by inositol phosphates and other intracellular messengers. Trends Endocrinol. Metab. 5 (1994) 256-260
27. Takagi Y., Nakajima T., Shimazaki A., Kageyama M., Matsugi T., Matsumura Y., Gabelt B.T., Kaufman P.L., and Hara H. Pharmacological characteristics of AFP-168 (tafluprost), a new prostanoid FP receptor agonist, as an ocular hypotensive drug. Exp. Eye Res. 78 (2004) 767-776
28. 2+-ATPases. Trends Pharmacol. Sci. 19 (1998) 131-135
29. Ushio-Fukai M., Abe S., Kobayashi S., Nishimura J., and Kanaide H. Effects of isoprenaline on cytosolic calcium concentrations and on tension in the porcine coronary artery. J. Physiol. 462 (1993) 679-696
30. Vanhoutte P.M. The endothelium and arterial reactivity. J. Mal. Vasc 11 (1986) 213-221
31. Weiss D.N., Podberesky D.J., Heidrich J., and Blaustein M.P. Nanomolar ouabain augments caffeine-evoked contractions in rat arteries. Am. J. Physiol. 265 (1993) C1443-C1448
32. Yoshitomi T., Yamaji K., Ishikawa H., and Ohnishi Y. Vasodilatory effects of nipradilol, an alpha- and beta-adrenergic blocker with nitric oxide releasing action, in rabbit ciliary artery. Exp. Eye Res. 75 (2002) 669-676
33. Yoshitomi T., Yamaji K., Ishikawa H., and Ohnishi Y. Vasodilatory mechanism of unoprostone isopropyl on isolated rabbit ciliary artery. Curr. Eye Res. 28 (2004) 167-174