Isoflavones and gamma irradiation inhibit cell growth in human salivary gland cells

Cancer Letters

Volumn 270, Issue 1, 2008, Pages 87-94

  Katz, J ^a   Blake, E ^a   Medrano, T A ^a   Sun, Y ^a   Shiverick, K T ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

Genistein; HSG cells; Oral cancer; Radiotherapy; Soy isoflavones; Vitamin E succinate

Indexed keywords

AGLYCONE; ALPHA TOCOPHEROL SUCCINATE; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; DAIDZEIN; GENISTEIN; GLUCOSIDE; ISOFLAVONE; NOVASOY; PROTEIN P53; SERINE; UNCLASSIFIED DRUG;

ARTICLE; CANCER THERAPY; CELL CYCLE; CELL GROWTH; CELL LINE; CLONOGENIC ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS; DRUG MECHANISM; GAMMA IRRADIATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; MOUTH CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RADIATION DOSE; RADIOSENSITIVITY; SALIVARY GLAND; SURVIVAL; WESTERN BLOTTING;

CELL CYCLE; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; GAMMA RAYS; GENISTEIN; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOFLAVONES; PHOSPHORYLATION; SALIVARY GLANDS; SOYBEANS; TUMOR SUPPRESSOR PROTEIN P53; VITAMIN E;

PHOS;

EID: 50649120139     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2008.04.051     Document Type: Article

References (38)

1. Chung C.H., Wong S., Ang K.K., et al. Strategic plans to promote head and neck cancer translational research within the radiation therapy oncology group: a report from the translational research program. Int. J. Radiat. Oncol. Biol. Phys. 69 (2007) S67-S78
2. Mageras G. Introduction management of target localization uncertainties in external beam therapy. Semin. Radiat. Oncol. 15 3 (2005) 133-135
3. Le Scodan R., Pommier P., Ardiet J.M., Montbarbon X., Malet C., Favrel V., Zrounba P., Poupart M., Ceruse P., Ferlay C., and Clippe S. Exclusive brachytherapy for T1 and T2 squamous cell carcinomas of the velotonsillar area: results in 44 patients. Int. Radiat. Oncol. Biol. Phys. 63 (2005) 441-448
4. Rubenstein E., Peterson D., Schubert M., et al. Clinical Practice guidelines for the prevention and treatment of cancer therapy-induced oral and gastrointestinal mucositis. Cancer 100 9 (2004) 2026-2046
5. Akimoto T., Nonaka T., Ishikawa H., Sakurai H., Saitoh J.I., Takahashi T., and Mitsuhashi N. Genistein a tyrosine kinase inhibitor, enhanced radiosensitivity in human esophageal cancer cell lines in vitro: possible involvement of inhibition of survival signal transduction pathways. Int. J. Radiat. Oncol. Biol. Phys. 50 (2001) 195-201
6. Konopacka M., and Rzeszowska J. Antioxidant Vitamins C, E and B-carotene reduce DNA damage before as well as after gamma-ray irradiation of human lymphocytes in vitro. Mutat. Res./Genet. Toxicol. Environ. Mutagen. 491 (2001) 1-7
7. Jha M.N., Bedford J., Cole W., Edward-Prasad J., and Kedar N. Vitamin E decreases mitotic accumulation in gamma-irradiated human tumor, but not in normal cells. Nutr. Cancer 35 2 (1999) 189-194
8. Rama B., and Prasad K. Study of the specificity of alpha-tocopherol (Vitamin E) acid succinate effects on melanoma, glioma and neuroblastoma cells in culture. Poc. Soc. Exp. Biol. Med. 174 (1983) 302-307
9. Delanian S., and Lefaix J.L. Current management for late normal tissue injury: radiation-induced fibrosis and necrosis. Semin. Radiat. Oncol. 17 (2007) 99-107
10. Noaman E., Zahran A.M., Kamal A.M., and Omran M.F. Vitamin E and selenium administered as modulator of antioxidant defense system: biochemical assessment and modification. Biol. Trace Elem. Res. 86 (2002) 55-64
11. Pagliacci M.C., Smacchia M., Migliorati G., Grignani F., Riccardi C., et al. Growth inhibitory effect of the natural phytooestrogen genistein in MCF-7 human breast cancer cells. Eur. J. Cancer 30A (1994) 675-1682
12. Mastukawa Y., Mauri N., Sakai T., Satomi Y., Toshida M., et al. Genistein arrests cell cycle progression at G2-M. Cancer Res. 53 (1993) 1328-1331
13. Kyle E., Neckers L., Takimoto C., Curt G., and Bergan R. Genistein-induced apoptosis of prostate cancer cells is preceded by a specific decrease in focal adhesion kinase activity. Mol. Pharmacol. 151 (1997) 193-200
14. Nagler R. Effect of radiotherapy and chemotherapeutic cytokines on a human salivary cell line. Anticancer Res. 18 (1988) 309-314
15. Rice L., Samedi V.G., Medrano T., Sweeney C., Baker H.V., Stenstrom A.G., Furman J., and Shiverick K.T. Mechanisms of the growth inhibitory effects of the isoflavone biochanin A on LNCaP cells and xenografts. Prostate 52 (2002) 201-212
16. Handayani R., Rice L.P., Cui Y., Medrano T.A., Samedi V.G., Baker H.V., Szabo N.J., and Shiverick K.T. Soy isoflavones alter expression of genes associated with cancer progression, including interleukin-8, in PC-3 human prostate cancer cells. J. Nutr. 136 (2006) 75-82
17. Drukteinis J.S., Medrano T., Kitzman J.M., and Shiverick K.T. Benzo(a)pyrene, but not 2,3,7,8-TCDD, induces G2/M cell cycle arrest, p21 CIP1, and p53 phosphorylation at serine-15 in human choriocarcinoma JEG-3 cells: a distinct signaling pathway. Placenta 26 (2005) S87-S95
18. Anai S., Good ison S., Shiverick K.T., Tanaka M., Hirao Y., and Rosser C.J. A combination of PTEN gene therapy and radiation therapy inhibits the growth of human prostate cancer PC-3 xeno graft tumors. Hum. Gene Ther. 17 (2006) 975-984
19. Barnes S., Peterson T.G., and Coward L. Rationale for the use of genistein-containing soy matrices in chemoprevention trials for breast and prostate cancer. J. Cell. Biochem. 22 (1995) 181-187
20. Zhou JR., Yu L., Zhong Y., Nassr RL., Franke AA., Gaston S.M., and Blackburn GL. Inhibition of orthotopic growth and metastasis of androgen-sensitive human prostate tumors in mice by bioactive soybean components. Prostate 53 2 (2002) 143-153
21. Adlercreutz H., Markkanen H., and Watanabe S. Plasma concentrations of phyto-oestrogens in Japanese men. Lancet 342 8881 (1993) 1209-1210
22. Miltyk W., Craciunescu CN., Fischer L., Reffcoat RA., Koch MA., Lopaczynski W., Mahoney C., Jeffcoat RA., Crowell J., Paglieri J., and Zeisel SH. Lack of significant genotoxicity of purified soy isoflavones (genistein, daidzein, and glycitein) in 20 patients with prostate cancer. Am. J. Clin. Nutr. 77 4 (2003) 875-882
23. Messina M.J., Parsky Stetchell K.D., and Barnes S. Soy intake and cancer risk: a review of the in vitro and in vivo data. Nutr. Cancer 21 (1994) 113-131
24. Horn-Ross PL., Morrow M., and Ljung BM. Diet and the risk of salivary gland cancer. Am. J. Epidem. 146 (1997) 171-176
25. Alhasan S.A., Ensley J.F., and Sarkar F.H. Genistein induced molecular changes in SCC of the head and neck cell line. Int. J. Oncol. 16 (2000) 333-338
26. Fotsis T., Pepper M., Aktas E., Breit S., Rasku S., et al. Flavonoids, dietary derived inhibitors of cell proliferation and in vitro angiogenesis. Cancer Res. 57 (1997) 2912-2916
27. Fotsis T., Pepper M., Adlercreutz H., Hase T., Montesano R., et al. Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis. J. Nutr. 125 (1995) 790S-979S Suppl
28. Alhasan S.A., Pietrasczkiwicz H., Alonso M., Sarkar J., and Fazlul H. Genistein-induced cell cycle arrest and apoptosis in a head and neck SCC cell line. Nutr. Cancer 34 (1999) 12-19
29. Moss R.W. Do antioxidants interfere with radiation therapy for cancer. Integr. Cancer Ther. 6 (2007) 281-292
30. Win W., Cao Z., Peng X., Trush M.A., and Li Y. Different effects of genistein and resveratrol on oxdiative DNA damage in vitro. Mutat. Res. 513 (2002) 113-120
31. Shintani S., Kiyota A., Mihara M., Sumida T., Nakashiro K., and Hamakawa H. Enhancement of radiosensitivity in head and neck cancer cells by ZD1839 (IRESSA), a selective epidermal growth factor receptor tyrosine kinase inhibitor. Am. J. Clin. Oncol. 26e (2003) 150-156
32. Rice L., Handayani R., Cui Y., Medrano T., Samedi V., Baker H., Szabo N.J., Rosser C.J., Goodison S., and Shiverick K.T. Soy isoflavones exert differential effects on androgen responsive genes in LNCaP human prostate cancer cells. J. Nutr. 137 (2007) 964-972
33. Noaman E., Zahran A.M., Kamal A.M., and Omran M.F. Vitamin E and selenium administration as modulator of antioxidant defense system: biochemical assessment and modification. Biol. Trace Elem. Res. 86 (2002) 55-64
34. Konopacka M., and Rzeszowska-Wolny J. Antioxidant vitamins C and E and beta-carotene reduce DNA damage before as well as after gamma-ray irradiation of human lymphocytes in vitro. Mutat. Res. 491 (2001) 1-7
35. Shintani S., Mihara M., Ueyama Y., Matsumura T., and Wong D.T.W. Cyclin D1 overexpression associates with radiosensitivity in oral squamous cell carcinoma. Int. J. Cancer Radiat. Oncol. Invest. 96 (2001) 159-165
36. Ferreira P.R., Fleck J.F., Diehl A., et al. Protective effect of alphatocopherol in head and neck cancer radiation-induced mucositis: a double-blind randomized trial. Head Neck 26 (2004) 313-321
37. 60 Co gamma rays on human tumor cells in vitro. Radiat. Res. 158 (2002) 311-318
38. Shintani S., Li C., Mihara M., Yano J., Terakado N., Nakashiro K., and Hamakawa H. P27KIP1, Skp2 and JAB1 expression and their clinical implications in oral squamous cell carcinoma. Head Neck Cancer 29 (2003) 210-216