Trials and tribulations in adult congenital heart disease

International Journal of Cardiology

Volumn 129, Issue 2, 2008, Pages 160-162

  Dimopoulos, Konstantinos ^a  

^a ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

ACE inhibitors; Adult congenital heart disease; Mustard operation; Randomised controlled trials; Systemic right ventricle

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; RAMIPRIL; SPIRONOLACTONE;

CLINICAL PRACTICE; CLINICAL TRIAL; CONGENITAL HEART DISEASE; EDITORIAL; EVIDENCE BASED MEDICINE; EXERCISE; EXERCISE TEST; EXERCISE TOLERANCE; FOLLOW UP; GREAT VESSELS TRANSPOSITION; HEART FAILURE; HEART SURGERY; HEART VENTRICLE SIZE; HUMAN; ISCHEMIC HEART DISEASE; MEDICAL PRACTICE; OXYGEN CONSUMPTION; PRIORITY JOURNAL; SYSTEMIC CIRCULATION;

ADULT; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANTIHYPERTENSIVE AGENTS; CARDIOVASCULAR SURGICAL PROCEDURES; HEART DEFECTS, CONGENITAL; HEART VENTRICLES; HUMANS; RAMIPRIL; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TREATMENT FAILURE;

EID: 50649119256     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2008.06.048     Document Type: Editorial

References (15)

1. Dimopoulos K., Diller G.P., Piepoli M.F., and Gatzoulis M.A. Exercise intolerance in adults with congenital heart disease. Cardiol Clin 24 (2006) 641-660 vii
2. Dimopoulos K., Diller G., Koltsida E., et al. Prevalence, predictors and prognostic value of renal dysfunction in adults with congenital heart disease. Circulation 117 (2008) 2320-2328
3. Dimopoulos K., Okonko D.O., Diller G.P., et al. Abnormal ventilatory response to exercise in adults with congenital heart disease relates to cyanosis and predicts survival. Circulation 113 (2006) 2796-2802
4. Spence M.S., Balaratnam M.S., and Gatzoulis M.A. Clinical update: cyanotic adult congenital heart disease. Lancet 370 (2007) 1530-1532
5. Therrien J., Provost Y., Harrison J., Connelly M., Kaemmerer H., and Webb G.D. Effect of angiotensin receptor blockade on systemic right ventricular function and size: A small, randomized, placebo-controlled study. Int J Cardiol 129 (2008) 187-192
6. Babu-Narayan S.V., Goktekin O., Moon J.C., et al. Late gadolinium enhancement cardiovascular magnetic resonance of the systemic right ventricle in adults with previous atrial redirection surgery for transposition of the great arteries. Circulation 111 (2005) 2091-2098
7. Konstam M.A., Udelson J.E., Anand I.S., and Cohn J.N. Ventricular remodeling in heart failure: a credible surrogate endpoint. J Card Fail 9 (2003) 350-353
8. Schulz K.F., and Grimes D.A. Sample size calculations in randomised trials: mandatory and mystical. Lancet 365 (2005) 1348-1353
9. Gatzoulis M.A., Webb G.D., and Daubeney P.E.F. Diagnosis and management of adult congenital heart disease (2003), Churchill Livingstone, Edinburgh
10. Diller G.P., Dimopoulos K., Okonko D., et al. Exercise intolerance in adult congenital heart disease: comparative severity, correlates, and prognostic implication. Circulation 112 (2005) 828-835
11. Engelfriet P., Boersma E., Oechslin E., et al. The spectrum of adult congenital heart disease in Europe: morbidity and mortality in a 5 year follow-up period. The Euro Heart Survey on adult congenital heart disease. Eur Heart J 26 (2005) 2325-2333
12. Dhruva S.S., and Redberg R.F. Variations between clinical trial participants and Medicare beneficiaries in evidence used for medicare national coverage decisions. Arch Intern Med 168 (2008) 136-140
13. Palange P., Ward S.A., Carlsen K.H., et al. Recommendations on the use of exercise testing in clinical practice. Eur Respir J 29 (2007) 185-209
14. Gatzoulis M.A. Adult congenital heart disease: education, education, education. Nat Clin Pract Cardiovasc Med 3 (2006) 2-3
15. Caldwell P.H., Murphy S.B., Butow P.N., and Craig J.C. Clinical trials in children. Lancet 364 (2004) 803-811