Detection and pharmacokinetics of alginate oligosaccharides in mouse plasma and urine after oral administration by a liquid chromatography/tandem mass spectrometry (LC-MS/MS) method

Bioscience, Biotechnology and Biochemistry

Volumn 72, Issue 8, 2008, Pages 2184-2190

  Nishikawa, Toru ^a,b   Yokose, Takeshi ^a,b   Yamamoto, Yoshiko ^b   Yamaguchi, Kenichi ^b   Oda, Tatsuya ^b  

^a Nagasaki Prefectural Institute for Environmental Research and Public Health   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

Alginate oligosaccharides; Digestive absorption; Liquid chromatography tandem mass spectrometry; Oral administration

Indexed keywords

ARCTIC ENGINEERING; COMPUTER NETWORKS; DIGESTIVE SYSTEM; MASS SPECTROMETERS; MASS SPECTROMETRY; OLIGOMERS; OLIGOSACCHARIDES; PHARMACOKINETICS; PLASMAS; POLYMERS; SENSITIVITY ANALYSIS; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS;

ALGINATE OLIGOSACCHARIDES; DIGESTIVE ABSORPTION; LC-MS/MS; LIQUID CHROMATOGRAPHY/ TANDEM MASS SPECTROMETRY; ORAL ADMINISTRATION;

BODY FLUIDS;

ALGINIC ACID; GLUCURONIC ACID; HEXURONIC ACID; OLIGOSACCHARIDE;

ANIMAL; ARTICLE; BLOOD; CHEMISTRY; LIQUID CHROMATOGRAPHY; MALE; METABOLISM; METHODOLOGY; MOUSE; ORAL DRUG ADMINISTRATION; TANDEM MASS SPECTROMETRY; URINE;

ADMINISTRATION, ORAL; ALGINATES; ANIMALS; CHROMATOGRAPHY, LIQUID; GLUCURONIC ACID; HEXURONIC ACIDS; MALE; MICE; OLIGOSACCHARIDES; TANDEM MASS SPECTROMETRY;

EID: 50649103328     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.80270     Document Type: Article

References (30)

1. Haug, A., Isolation and fractionation with potassium chloride and manganous ions. Methods Carbohydr. Chem., 5, 69-73 (1965).
2. Scott, C. D., Immobilized cells: a review of recent literature. Enzyme Microb. Technol., 9, 66-73 (1987).
3. Kurachi, M., Nakashima, T., Miyajima, C., Iwamoto, Y., Muramatsu, T., Yamaguchi, K., and Oda, T., Comparison of the activities of various alginates to induce TNF-alpha secretion in RAW264.7 cells. J. Infect. Chemother., 11, 199-203 (2005).
4. Yonemoto, Y., Tanaka, H., Yamashita, T., Kitabatake, N., Ishida, Y., Kimura, A., and Murata, K., Promotion of germination and shoot elongation of some plants by alginate oligomers prepared with bacterial alginate lyase. J. Ferment. Bioeng., 75, 68-70 (1993).
5. Tomoda, Y., Uemura, K., and Adachi, T., Promotion of barley root elongation under hypoxic conditions by alginate lyase-lysate (A.L.L). Biosci. Biotechnol. Biochem., 58, 202-203 (1994).
6. Iwasaki, K., and Matsubara, Y., Purification of alginate oligosaccharides with root growth-promoting activity toward lettuce. Biosci. Biotechnol. Biochem., 64, 1067-1070 (2000).
7. Kawada, A., Hiura, N., Tajima, S., and Takahara, H., Alginate oligosaccharides stimulate VEGF-mediated growth and migration of human endothelial cells. Arch. Dermatol. Res., 291, 542-547 (1999).
8. Kawada, A., Hiura, N., Shiraiwa, M., Tajima, S., Hiruma, M., Hara, K., Ishibashi, A., and Takahara, H., Stimulation of human keratinocyte growth by alginate oligosaccharides, a possible co-factor for epidermal growth factor in cell culture. FEBS Lett., 408, 43-46 (1997).
9. Iwamoto, Y., Xu, X., Tamura, T., Oda, T., and Muramatsu, T., Enzymatically depolymerized alginate oligomers that cause cytotoxic cytokine production in human mononuclear cells. Biosci. Biotechnol. Biochem., 67, 258-263 (2003).
10. Yamamoto, Y., Kurachi, M., Yamaguchi, K., and Oda, T., Induction of multiple cytokine secretion from RAW264.7 cells by alginate oligosaccharides. Biosci. Biotechnol. Biochem., 71, 238-241 (2007).
11. Yamamoto, Y., Kurachi, M., Yamaguchi, K., and Oda, T., Stimulation of multiple cytokine production in mice by alginate oligosaccharides following intraperitoneal administration. Carbohydr. Res., 342, 1133-1137 (2007).
12. Uno, T., Hattori, M., and Yoshida, T., Oral administration of alginic acid oligosaccharide suppresses IgE production and inhibits the induction of oral tolerance. Biosci. Biotechnol. Biochem., 70, 3054-3057 (2006).
13. Hiura, N., Chaki, T., and Ogawa, H., Antihypertensive effects of sodium alginate oligosaccharides. Nippon Nōgeikagaku Kaishi (in Japanese), 75, 783-785 (2001).
14. Tsuchida, T., Chaki, T., Hiura, N., and Satou, R., Effects of sodium alginate oligosaccharide on human blood pressure. Med. Cons. New-Remed. (in Japanese), 38, 555-560 (2001).
15. Chaki, T., Nishimoto, S., Hiura, N., Satou, R., Tou, Y., and Kakinuma, S., Effects of a powdered drink containing sodium alginate oligosaccharide on blood pressure in mild hypertensive and high normal blood pressure subjects. J. Nutr. Food (in Japanese), 5, 41-54 (2002).
16. Chaki, T., Kajimoto, N., Ogawa, H., Baba, T., and Hiura, N., Metabolism and calcium antagonism of sodium alginate oligosaccharides. Biosci. Biotechnol. Biochem., 71, 1819-1825 (2007).
17. Iwamoto, Y., Hidaka, H., Oda, T., and Muramatsu, T., A study of tryptophan fluorescence quenching of bifunctional alginate lyase from a marine bacterium Pseudoalteromonas sp. strain No. 272 by acrylamide. Biosci. Biotechnol. Biochem., 67, 1990-1992 (2003).
18. Suzuki, S., Kakehi, K., and Honda, S., Comparison of the sensitivities of various derivatives of oligosaccharides in LC-MS with fast atom bombardment and electrospray ionization interfaces. Anal. Chem., 68, 2073-2083 (1996).
19. Koizumi, K., Separation and analysis of saccharides - on mainly oligosaccharides. Yakugaku Zasshi (in Japanese), 119, 199-214 (1999).
20. McIntosh, T. S., Davis, H. M., and Matthews, D. E., A liquid chromatography-mass spectrometry method to measure stable isotopic tracer enrichment of glycerol and glucose in human serum. Anal. Biochem., 300, 163-169 (2002).
21. Wunschel, D., Fox, K. F., Fox, A., Nagpal, M. L., Kim, K., Stewart, G. C., and Shahgholi, M., Quantitative analysis of neutral and acidic sugars in whole bacterial cell hydrolysates using high-performance anion-exchange liquid chromatography-electrospray ionization tandem mass spectrometry. J. Chromatogr., 776, 205-219 (1997).
22. Nakao, C., Gamoh, K., Hishida, K., and Wada, H., Ligand exchange liquid chromatography/mass spectrometry of mono- and oligosaccharides. J. Mass Spectrom. Soc. Jpn. (in Japanese), 54, 49-56 (2006).
23. Zhang, Z., Yu, G., Zhao, X., Liu, H., and Guan, H., Sequence analysis of alginate-derived oligosaccharide by negative-ion electrospray tandem mass spectrometry. J. Am. Soc. Mass Spectrum., 17, 621-630 (2006).
24. Chaki, T., Kakimi, H., Shibata, A., and Baba, T., Detection of alginate oligosaccharides from mollusks. Biosci. Biotechnol. Biochem., 70, 2793-2796 (2006).
25. Liu, Y., Jiang, X. L., Cui, H., and Guan, H. S., Analysis of oligomannuronic acids and oligoguluronic acids by high-performance anion-exchange chromatography and electrospray ionization mass spectrometry. J. Chromatogr. A, 884, 105-111 (2000).
26. Mei, H., Hsieh, Y., Nardo, C., Xu, X., Wang, S., Ng, K., and Korfmacher, W. A., Investigation of matrix effects in bioanalytical high-performance liquid chromatography/tandem mass spectrometric assays: application to drug discovery. Rapid Commun. Mass Spectrom., 17, 97-103 (2003).
27. Lipinski, C. A., Lombardo, F., Dominy, B. W., and Feeney, P. J., Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev., 46, 3-26 (1997).
28. Ferraris, R. P., Dietary and developmental regulation of intestinal sugar transport. Biochem. J., 360, 265-276 (2001).
29. Humphreys, E. R., and Triffitt, J. T., Absorption by rats of alginate labeled with carbon-14. Nature, 219, 1172-1173 (1968).
30. Inui, K. I., Masuda, S., and Saito, H., Cellular and molecular aspects of drug transport in the kidney. Kidney Int., 58, 944-958 (2000).