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Volumn 14, Issue 3, 2008, Pages 201-209

Possible indirect detection of rHuEPO administration in human urine by high-performance liquid chromatography tandem mass spectrometry

Author keywords

ADMA; Arginine; Citrulline; Collision induced dissociation; Doping; Erythropoietin; Fragmentation; Indirect method; Liquid chromatography; Mass spectrometry; SDMA; Sport

Indexed keywords

AMIDASE; ARGININE; BIOLOGICAL MARKER; CITRULLINE; DIMETHYLARGININASE; DIMETHYLARGININE; DRUG DERIVATIVE; NITRIC OXIDE SYNTHASE; RECOMBINANT ERYTHROPOIETIN;

EID: 50649091590     PISSN: 14690667     EISSN: None     Source Type: Journal    
DOI: 10.1255/ejms.922     Document Type: Article
Times cited : (13)

References (27)
  • 1
    • 0037114935 scopus 로고    scopus 로고
    • Detection of isoelectric profiles of erythropoietin in urine: Differentiation of natural and administered recombinant hormones
    • doi: 10.1016/ S0003-2697(02)00407-4
    • F. Lasne, L. Martin, N. Crepin and J. Ceaurriz, "Detection of isoelectric profiles of erythropoietin in urine: differentiation of natural and administered recombinant hormones", Anal. Biochem. 311, 119 (2002). doi: 10.1016/ S0003-2697(02)00407-4
    • (2002) Anal. Biochem , vol.311 , pp. 119
    • Lasne, F.1    Martin, L.2    Crepin, N.3    Ceaurriz, J.4
  • 2
    • 0036840574 scopus 로고    scopus 로고
    • Comparison of the Isoelectric Focusing Patterns of Darbepoetin Alfa, Recombinant Human Erythropoietin and Endogenous Erythropoietin from Human Urine
    • D.H. Catlin, A. Breidbach, S. Elliott and J. Glaspy, "Comparison of the Isoelectric Focusing Patterns of Darbepoetin Alfa, Recombinant Human Erythropoietin and Endogenous Erythropoietin from Human Urine", Clin. Chem. 48, 2057 (2002).
    • (2002) Clin. Chem , vol.48 , pp. 2057
    • Catlin, D.H.1    Breidbach, A.2    Elliott, S.3    Glaspy, J.4
  • 4
    • 0035141379 scopus 로고    scopus 로고
    • Soluble transferrin receptor (sTfR) concentration quantided using two sTfR kits: Analytical and clinical performance characteristics
    • doi: 10.1016/S0009-8981(00)00376-4
    • F.H.Jr. Wians, J.E. Urban, S.H. Kroft and J.H. Keffer, "Soluble transferrin receptor (sTfR) concentration quantided using two sTfR kits: analytical and clinical performance characteristics", Clin. Chim. Acta. 303, 75 (2001). doi: 10.1016/S0009-8981(00)00376-4
    • (2001) Clin. Chim. Acta , vol.303 , pp. 75
    • Wians Jr., F.H.1    Urban, J.E.2    Kroft, S.H.3    Keffer, J.H.4
  • 6
    • 0032993366 scopus 로고    scopus 로고
    • Erythropoietin depresses nitric oxide synthase expression by human endothelial cells
    • X.Q. Wang and N.D. Vaziri, "Erythropoietin depresses nitric oxide synthase expression by human endothelial cells", Hypertension 33, 894 (1999).
    • (1999) Hypertension , vol.33 , pp. 894
    • Wang, X.Q.1    Vaziri, N.D.2
  • 9
    • 1942438521 scopus 로고    scopus 로고
    • Asymmetrical dimethylarginine. The Uber marker?
    • doi: 10.1161/01. CIR.0000126823.07732.D5
    • J.P. Cooke, "Asymmetrical dimethylarginine. The Uber marker?", Circulation 109, 1813 (2004). doi: 10.1161/01. CIR.0000126823.07732.D5
    • (2004) Circulation , vol.109 , pp. 1813
    • Cooke, J.P.1
  • 10
    • 2942577486 scopus 로고    scopus 로고
    • Cardiovascular biology of the asymmetric dimethylarginine: Dimethylarginine dimethylaminohydrolase pathway
    • doi: 10.1161/01. ATV.0000128897.54893.26
    • P. Vallance and J. Leiper, "Cardiovascular biology of the asymmetric dimethylarginine: Dimethylarginine dimethylaminohydrolase pathway", Arterioscler. Thromb. Vasc. Biol. 24, 1023 (2004). doi: 10.1161/01. ATV.0000128897.54893.26
    • (2004) Arterioscler. Thromb. Vasc. Biol , vol.24 , pp. 1023
    • Vallance, P.1    Leiper, J.2
  • 11
    • 22844437495 scopus 로고    scopus 로고
    • Erythropoietin increases asymmetric dimethylarginine in endothelial cells: Role of dimethylarginine dimethylaminohydrolase
    • doi: 10.1681/ ASN.2004090735
    • F. Scalera, J.T. Kielstein, J. Martens-Lobenhoffer, S.C. Postel, M. Täger and S.M. Bode-Böger, "Erythropoietin increases asymmetric dimethylarginine in endothelial cells: role of dimethylarginine dimethylaminohydrolase", J. Am. Soc. Nephrol. 16, 892 (2005). doi: 10.1681/ ASN.2004090735
    • (2005) J. Am. Soc. Nephrol , vol.16 , pp. 892
    • Scalera, F.1    Kielstein, J.T.2    Martens-Lobenhoffer, J.3    Postel, S.C.4    Täger, M.5    Bode-Böger, S.M.6
  • 12
    • 33644533171 scopus 로고    scopus 로고
    • Fast and efficient determination of arginine, aymmetric dimethylarginine and asymmetric dimethylarginine in biological fluids by hydrophilic-interaction liquid chromatography-electrospray tandem mass spectrometry
    • doi: 10.1373/clinchem.2005.060152
    • J. Martens-Lobenhoffer and S.M. Bode-Böger, "Fast and efficient determination of arginine, aymmetric dimethylarginine and asymmetric dimethylarginine in biological fluids by hydrophilic-interaction liquid chromatography-electrospray tandem mass spectrometry", Clin. Chem. 52, 488 (2006). doi: 10.1373/clinchem.2005.060152
    • (2006) Clin. Chem , vol.52 , pp. 488
    • Martens-Lobenhoffer, J.1    Bode-Böger, S.M.2
  • 13
    • 34848821201 scopus 로고    scopus 로고
    • K. Chobanyan, T. Thum, M.T. Suchy, B Zhu, A. Mitschke, F.M. Gutzki, B. Beckmann, D.O. Stichtenoth and D. Tsikas, GC-MS assay for hepatic DDAH activity in diabetic and non-diabetic rats by measuring dimethylamine (DMA) formed from asymmetric dimethylarginine (ADMA): Evaluation of the importance of S-nitrosothiots as inhibitors of DDAH activity in vitro and in vivo in humans, J. Chromatogr. B Anatyt. Technol. Biomed. Life Sci. 858, 32 (2007). doi: 10.1016/j. jchromb.2007.08.002
    • K. Chobanyan, T. Thum, M.T. Suchy, B Zhu, A. Mitschke, F.M. Gutzki, B. Beckmann, D.O. Stichtenoth and D. Tsikas, "GC-MS assay for hepatic DDAH activity in diabetic and non-diabetic rats by measuring dimethylamine (DMA) formed from asymmetric dimethylarginine (ADMA): Evaluation of the importance of S-nitrosothiots as inhibitors of DDAH activity in vitro and in vivo in humans", J. Chromatogr. B Anatyt. Technol. Biomed. Life Sci. 858, 32 (2007). doi: 10.1016/j. jchromb.2007.08.002
  • 14
    • 34248180612 scopus 로고    scopus 로고
    • D. Tsikas, T. Thum, T. Becker, V.V. Pham, K. Chobanyan, A. Mitschke, B. Beckmann, F.M. Gutzki, J. Bauersachs and D.O. Stichtenoth, Accurate quantification of dimethylamine (DMA) in human urine by gas chromatography-mass spectrometry as pentafluorobenzamide derivative: evaluation of the relationship between DMA and its precursor asymmetric dimethylarginine (ADMA) in health and disease, J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 851, 229 (2007). doi: 10.1016/j. jchromb.2006.09.015
    • D. Tsikas, T. Thum, T. Becker, V.V. Pham, K. Chobanyan, A. Mitschke, B. Beckmann, F.M. Gutzki, J. Bauersachs and D.O. Stichtenoth, "Accurate quantification of dimethylamine (DMA) in human urine by gas chromatography-mass spectrometry as pentafluorobenzamide derivative: evaluation of the relationship between DMA and its precursor asymmetric dimethylarginine (ADMA) in health and disease", J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 851, 229 (2007). doi: 10.1016/j. jchromb.2006.09.015
  • 15
    • 34248191785 scopus 로고    scopus 로고
    • Accurate quantification of dimethylamine (DMA) in human plasma and serum by GC-MS and GC-tandem MS as pentafluorobenzamide derivative in the positive-ion chemical ionization mode
    • doi: 10.1016/j.jchromb.2007.03.006
    • K. Chobanyan, A. Mitschke, F.M. Gutzki, D.O. Stichtenoth and D. Tsikas, "Accurate quantification of dimethylamine (DMA) in human plasma and serum by GC-MS and GC-tandem MS as pentafluorobenzamide derivative in the positive-ion chemical ionization mode", J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 851, 240 (2007). doi: 10.1016/j.jchromb.2007.03.006
    • (2007) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci , vol.851 , pp. 240
    • Chobanyan, K.1    Mitschke, A.2    Gutzki, F.M.3    Stichtenoth, D.O.4    Tsikas, D.5
  • 16
    • 34547901469 scopus 로고    scopus 로고
    • Reference values for plasma concentrations of asymmetrical dimethylarginine (ADMA) and other arginine metabolites in men after validation of a chromatographic method
    • doi: 10.1016/j.cca.2007.07.006
    • A. Meinitzer, M. Puchinger, B.M. Winklhofer-Roob, E. Rock, J. Ribalta, J.M. Roob, I. Sundl, G. Halwachs-Baumann and W. März, "Reference values for plasma concentrations of asymmetrical dimethylarginine (ADMA) and other arginine metabolites in men after validation of a chromatographic method", Clin. Chim. Acta. 384, 141 (2007). doi: 10.1016/j.cca.2007.07.006
    • (2007) Clin. Chim. Acta , vol.384 , pp. 141
    • Meinitzer, A.1    Puchinger, M.2    Winklhofer-Roob, B.M.3    Rock, E.4    Ribalta, J.5    Roob, J.M.6    Sundl, I.7    Halwachs-Baumann, G.8    März, W.9
  • 17
    • 36148933356 scopus 로고    scopus 로고
    • Sensitivity enhancement of a GC-MS/MS method for asymmetric dimethylarginine (ADMA) by plasma ultrafiltrate reduction
    • doi: 10.1016/j. ab.2007.09.010
    • B. Beckmann, F.M. Gutzki and D. Tsikas, "Sensitivity enhancement of a GC-MS/MS method for asymmetric dimethylarginine (ADMA) by plasma ultrafiltrate reduction", Anal. Biochem. 372, 264 (2008). doi: 10.1016/j. ab.2007.09.010
    • (2008) Anal. Biochem , vol.372 , pp. 264
    • Beckmann, B.1    Gutzki, F.M.2    Tsikas, D.3
  • 18
    • 34248189154 scopus 로고    scopus 로고
    • HPLC analysis of ADMA and other methylated L-arginine analogs in biological fluids
    • doi: 10.1016/j.jchromb.2006.07.024
    • T. Teerlink, "HPLC analysis of ADMA and other methylated L-arginine analogs in biological fluids", J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 851, 21 (2007). doi: 10.1016/j.jchromb.2006.07.024
    • (2007) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci , vol.851 , pp. 21
    • Teerlink, T.1
  • 19
    • 31544457631 scopus 로고    scopus 로고
    • Comparison of HPLC method and commercial ELISA assay for asymmetric dimethylarginine (ADMA) determination in human serum
    • doi: 10.1016/j. jchromb.2005.11.015
    • F. Schulze, E. Schwedhelm, R. Maas and R.H. Böger, "Comparison of HPLC method and commercial ELISA assay for asymmetric dimethylarginine (ADMA) determination in human serum", J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 831, 333 (2006). doi: 10.1016/j. jchromb.2005.11.015
    • (2006) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci , vol.831 , pp. 333
    • Schulze, F.1    Schwedhelm, E.2    Maas, R.3    Böger, R.H.4
  • 20
    • 14144252472 scopus 로고    scopus 로고
    • High-performance liquid chromatographic assay of N(G)-monomethyl-L-arginine, N(G),N(G)-dimethyl-L- arginine and N(G),N(G)'-dimethyl-L-arginine using 4-fluoro-7-nitro-2, 1,3-benzoxadiazole as a fluorescent reagent
    • doi: 10.1016/j. chroma.2005.01.052
    • S. Nonaka, M. Tsunoda, K. Imai, T. Funatsu. "High-performance liquid chromatographic assay of N(G)-monomethyl-L-arginine, N(G),N(G)-dimethyl-L- arginine and N(G),N(G)'-dimethyl-L-arginine using 4-fluoro-7-nitro-2, 1,3-benzoxadiazole as a fluorescent reagent", J. Chromatogr. A. 1066, 41 (2005). doi: 10.1016/j. chroma.2005.01.052
    • (2005) J. Chromatogr. A , vol.1066 , pp. 41
    • Nonaka, S.1    Tsunoda, M.2    Imai, K.3    Funatsu, T.4
  • 21
    • 35748979118 scopus 로고    scopus 로고
    • Direct analysis of un-derivatized asymmetric dimethylarginine (ADMA) and L-arginine from plasma using mixed-mode ion-exchange liquid chromatography- tandem mass spectrometry
    • doi: 10.1016/j.jchromb.2007.09.024
    • M.J. Bishop, B. Crow, D. Norton, E. Paliakov, J. George and J.A. Bralley, "Direct analysis of un-derivatized asymmetric dimethylarginine (ADMA) and L-arginine from plasma using mixed-mode ion-exchange liquid chromatography- tandem mass spectrometry", J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 859, 164 (2007). doi: 10.1016/j.jchromb.2007.09.024
    • (2007) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci , vol.859 , pp. 164
    • Bishop, M.J.1    Crow, B.2    Norton, D.3    Paliakov, E.4    George, J.5    Bralley, J.A.6
  • 22
    • 34248190179 scopus 로고    scopus 로고
    • High-throughput liquid chromatographic-tandem mass spectrometric determination of arginine and dimethylated arginine derivatives in human and mouse plasma
    • doi: 10.1016/j. jchromb.2006.11.052
    • E. Schwedhelm, R. Maas, J. Tan-Andresen, F. Schulze, U. Riederer and R.H. Böger, "High-throughput liquid chromatographic-tandem mass spectrometric determination of arginine and dimethylated arginine derivatives in human and mouse plasma", J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 851, 211 (2007). doi: 10.1016/j. jchromb.2006.11.052
    • (2007) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci , vol.851 , pp. 211
    • Schwedhelm, E.1    Maas, R.2    Tan-Andresen, J.3    Schulze, F.4    Riederer, U.5    Böger, R.H.6
  • 23
    • 34248154258 scopus 로고    scopus 로고
    • Chromatographic- mass spectrometric methods for the quantification of L-arginine and its methylated metabolites in biological fluids
    • doi: 10.1016/j. jchromb.2006.07.038
    • J. Martens-Lobenhoffer and S.M. Bode-Böger, "Chromatographic- mass spectrometric methods for the quantification of L-arginine and its methylated metabolites in biological fluids", J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 851, 30 (2007). doi: 10.1016/j. jchromb.2006.07.038
    • (2007) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci , vol.851 , pp. 30
    • Martens-Lobenhoffer, J.1    Bode-Böger, S.M.2
  • 24
    • 0038000050 scopus 로고    scopus 로고
    • Detection of arginine dimethylated peptides by parallel precursor ion scanning mass spectrometry in positive ion mode
    • doi: 10.1021/ac026283q
    • J. Rappsilber, W.J. Friesen, S. Paushkin, G. Dreyfuss and M. Mann, "Detection of arginine dimethylated peptides by parallel precursor ion scanning mass spectrometry in positive ion mode", Anal. Chem. 75, 3107 (2003). doi: 10.1021/ac026283q
    • (2003) Anal. Chem , vol.75 , pp. 3107
    • Rappsilber, J.1    Friesen, W.J.2    Paushkin, S.3    Dreyfuss, G.4    Mann, M.5
  • 25
    • 1942534606 scopus 로고    scopus 로고
    • A mass spectrometry based method for distinguishing between symmetrically and asymmetrically dimethylated arginine residues
    • doi: 10.1002/rcm.1421
    • C.J. Brame, M.F. Moran and L.D. McBroom-Cerajewski, "A mass spectrometry based method for distinguishing between symmetrically and asymmetrically dimethylated arginine residues", Rapid Commun. Mass Spectrom. 18, 877 (2004). doi: 10.1002/rcm.1421
    • (2004) Rapid Commun. Mass Spectrom , vol.18 , pp. 877
    • Brame, C.J.1    Moran, M.F.2    McBroom-Cerajewski, L.D.3
  • 26
    • 0842310469 scopus 로고    scopus 로고
    • Fragmentation pathways of NG-methylated and unmodified arginine residues in peptides studied by ESi-MS/MS and MALDI-MS
    • doi: 10.1016/j. jasms.2003.10.002
    • P.M. Gehring, P.E. Hunziker, S. Zahariev and S. Pongor, "Fragmentation pathways of NG-methylated and unmodified arginine residues in peptides studied by ESi-MS/MS and MALDI-MS", J. Am. Soc. Mass Spectrom. 15, 142 (2004). doi: 10.1016/j. jasms.2003.10.002
    • (2004) J. Am. Soc. Mass Spectrom , vol.15 , pp. 142
    • Gehring, P.M.1    Hunziker, P.E.2    Zahariev, S.3    Pongor, S.4


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