HPLC-DAD and MS/MS analysis of novel drug candidates from the group of aromatic hydrazones revealing the presence of geometric isomers

Journal of Pharmaceutical and Biomedical Analysis

Volumn 48, Issue 2, 2008, Pages 295-302

  Kovaříková, Petra ^a   Vávrová, Kateřina ^a   Tomalová, Kateřina ^a   Schöngut, Michal ^a   Hrušková, Kateřina ^a   Hašková, Pavlína ^b   Klimeš, Jiří ^a  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Aroylhydrazones; Geometric isomers; HPLC DAD; HPLC MS; Iron chelators

Indexed keywords

2' HYDROXYACETOPHENONE ISONICOTINOYLHYDRAZONE; 2' HYDROXYPROPIOPHENONE ISONICOTINOYLHYDRAZONE; HYDRAZONE DERIVATIVE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; DRUG DETERMINATION; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION TRAP MASS SPECTROMETRY; ISOMER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; ULTRAVIOLET SPECTROSCOPY;

ALDEHYDES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDRAZONES; ISOMERISM; MASS SPECTROMETRY;

EID: 50649087711     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2007.12.017     Document Type: Article

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