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Volumn 28, Issue 12, 2005, Pages 1300-1306
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Development of high-performance liquid chromatographic determination of salicylaldehyde isonicotinoyl hydrazone in rabbit plasma and application of this method to an in vivo study
a
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Author keywords
HPLC; Iron chelator; Pharmacokinetics; Salicylaldehyde isonicotinoyl hydrazone; SIH
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Indexed keywords
ACETONITRILE;
DRUG PRODUCTS;
PHARMACOKINETICS;
PHASE SEPARATION;
PLASMAS;
PRECIPITATION (CHEMICAL);
PROTEINS;
SOLVENT EXTRACTION;
IRON-CHELATOR;
PROTEIN PRECIPITATION;
RABBIT PLASMA;
SALICYLALDEHYDE ISONICOTINOYL HYDRAZONE;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
ACETONITRILE;
BUFFER;
CARBON;
EDETIC ACID;
HYDRAZONE DERIVATIVE;
METHANOL;
PENTOBARBITAL;
PHOSPHATE;
PYRIDOXAL 2 CHLOROBENZOYLHYDRAZONE;
PYRIDOXAL ISONICOTINOYLHYDRAZONE;
SALICYLALDEHYDE ISONICOTINOYLHYDRAZONE;
SODIUM DIHYDROGEN PHOSPHATE;
UNCLASSIFIED DRUG;
WATER;
ACCURACY;
ANALYTIC METHOD;
ANIMAL EXPERIMENT;
ARTICLE;
COLUMN CHROMATOGRAPHY;
CONCENTRATION (PARAMETERS);
CONCENTRATION RESPONSE;
CONTROLLED STUDY;
DRUG BLOOD LEVEL;
DRUG DETERMINATION;
DRUG STRUCTURE;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
IN VIVO STUDY;
LINEAR SYSTEM;
LIQUID LIQUID EXTRACTION;
MALE;
NONHUMAN;
PHASE SEPARATION;
PRECIPITATION;
PRIORITY JOURNAL;
PROTEIN ANALYSIS;
QUANTITATIVE ANALYSIS;
RABBIT;
REPRODUCIBILITY;
SAMPLING;
SEPARATION TECHNIQUE;
SOLID PHASE EXTRACTION;
STATISTICAL SIGNIFICANCE;
VALIDATION PROCESS;
ALDEHYDES;
ANIMALS;
BLOOD CHEMICAL ANALYSIS;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
DRUG STABILITY;
HYDRAZONES;
IRON CHELATING AGENTS;
MALE;
QUALITY CONTROL;
RABBITS;
ORYCTOLAGUS CUNICULUS;
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EID: 23944448097
PISSN: 16159306
EISSN: None
Source Type: Journal
DOI: 10.1002/jssc.200500077 Document Type: Article |
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Times cited : (31)
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References (17)
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