Short-term treatment of stroke-prone spontaneously hypertensive rats with an AT1 receptor blocker protects against hypertensive end-organ damage by prolonged inhibition of the renin-angiotensin system

Clinical and Experimental Pharmacology and Physiology

Volumn 35, Issue 10, 2008, Pages 1151-1155

  Hamaguchi, Rika ^a   Takemori, Kumiko ^a   Inoue, Takao ^a   Masuno, Kouichi ^a   Ito, Hiroyuki ^a  

^a KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Angiotensin II; Angiotensin II receptor blocker; Cerebral oedema; Hypertension; Oxidative stress

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN II; CANDESARTAN; DIPEPTIDYL CARBOXYPEPTIDASE; HYDROPEROXIDE; INTERCELLULAR ADHESION MOLECULE 1; RENIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE VARIABILITY; BRAIN CORTEX; BRAIN EDEMA; CONTROLLED STUDY; ENZYME ACTIVITY; ESSENTIAL HYPERTENSION; KIDNEY; KIDNEY FUNCTION; MALE; NONHUMAN; ORGAN INJURY; OXIDATIVE STRESS; PLASMA RENIN ACTIVITY; PROTEIN EXPRESSION; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SHORT COURSE THERAPY; STROKE PRONE SPONTANEOUSLY HYPERTENSIVE RAT;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BLOOD PRESSURE; BRAIN EDEMA; HYPERTENSION; KIDNEY FUNCTION TESTS; MALE; OXIDATIVE STRESS; RATS; RATS, INBRED SHR; RECEPTOR, ANGIOTENSIN, TYPE 1; RENIN-ANGIOTENSIN SYSTEM; STROKE; TIME FACTORS;

EID: 50649083061     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2008.04973.x     Document Type: Article

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