Coupled mother-child model for bioaccumulation of POPs in nursing infants

Environmental Pollution

Volumn 156, Issue 1, 2008, Pages 90-98

  Trapp, Stefan ^a   Ma Bomholtz, Li ^a   Legind, Charlotte N ^a,b  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Accumulation; Breast milk; Human exposure; Infant; Model; POP

Indexed keywords

ARSENIC COMPOUNDS; BIOACCUMULATION; BIOCHEMISTRY; CHLORINE COMPOUNDS; FOOD PRODUCTS PLANTS; INDUSTRIAL CHEMICALS; NURSING; ORGANIC COMPOUNDS; ORGANIC POLLUTANTS; RISK ASSESSMENT; RISK MANAGEMENT; SAFETY ENGINEERING;

ACCUMULATION; BIOACCUMULATION FACTORS; BREAST MILK; CHEMICAL RISK ASSESSMENT; COUPLED MODELING; HUMAN EXPOSURE; HUMAN MILK; INFANT; MODEL; PERSISTENT ORGANIC POLLUTANTS; POP;

ORGANIC CHEMICALS;

ORGANIC COMPOUND; VOLATILE AGENT;

BIOACCUMULATION; BREASTFEEDING; MILK; MODEL; ORGANIC POLLUTANT; PERSISTENCE; POLLUTION EXPOSURE; RISK ASSESSMENT; VOLATILE SUBSTANCE;

ADULT; ARTICLE; BIOACCUMULATION; BREAST MILK; CHILD; FEMALE; HUMAN; INFANT NUTRITION; MATHEMATICAL MODEL; MILK; MOTHER CHILD RELATION; ORGANIC POLLUTION; POLLUTANT; PREDICTION; RISK ASSESSMENT; STRUCTURE ANALYSIS;

ADIPOSE TISSUE; BREAST FEEDING; ENVIRONMENTAL POLLUTANTS; FOOD CONTAMINATION; HUMANS; INFANT; INFANT, NEWBORN; INHALATION EXPOSURE; LACTATION; MILK, HUMAN; MODELS, BIOLOGICAL; ORGANIC CHEMICALS; TETRACHLORODIBENZODIOXIN;

EID: 50549104344     PISSN: 02697491     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.envpol.2007.12.036     Document Type: Article

References (35)

1. BgVV (Bundesinstitut für gesundheitlichen Verbraucherschutz und Veterinärmedizin). Trends der Rückstandsgehalte in Frauenmilch der Bundesrepublik Deutschland - Aufbau der Frauenmilch- und Dioxin-Humandatenbank am BgVV (2000). http://www.bfr.bund.de/cd/432 (accessed 12.03.06)
2. CEHAPE Children's Environment and Health Action Plan for Europe, 2004. Fourth Ministerial Conference on Environment and Health, Budapest, Hungary, 23-25 June 2004. Working paper. http://www.euro.who.int/document/che/edoc07.pdf (accessed 04.07.07).
3. Czub G., and McLachlan M.S. Bioaccumulation potential of persistent organic chemicals in humans. Environ. Sci. Technol. 38 (2004) 2406-2412
4. Czub G., and McLachlan M.S. A food chain model to predict the levels of lipophilic organic contaminants in humans. Environ. Toxicol. Chem. 23 (2004) 2356-2366
5. Dahl P., Lindström G., Wiberg K., and Rappe C. Absorption of polychlorinated biphenyls, dibenzo-p-dioxins and dibenzofurans by breast-fed infants. Chemosphere 30 (1995) 2297-2306
6. Deurenberg P., Weststrate J.A., and Seidell J.C. Body mass index as a measure of body fatness: age- and sex-specific prediction formulas. Br. J. Nutr. 65 (1991) 105-114
7. EC (European Commission), 1996. EUSES, the European Union System for the Evaluation of Substances. National Institute of Public Health and the Environment (RIVM), The Netherlands. Available from the European Chemicals Bureau (EC/DG XI), Ispra, Italy.
8. EC (European Commission), 2003. Technical Guidance Document on Risk Assessment in Support of Commission Directive 93/67/EEC on Risk Assessment for New Notified Substances, Commission Regulation (EC) No 1488/94 on Risk Assessment for Existing Substances, and Directive 98/8/EC of the European Parliament and of the Council Concerning the Placing of Biocidal Products on the Market. Available from: http://ecb.jrc.it/documents/.
9. Filser J.G., Baur C., Csanády G., Kessler W., and Kreuzer P.E. Toxicokinetic modeling as a tool for risk estimation: 2,3,7,8-tetrachlorodibenzo-p-dioxin. Int. J. Toxicol. 16 (1997) 433-448
10. Harris C.A., Woolridge M.W., and Hay A.W.M. Factors affecting the transfer of organochlorine pesticide residues to breastmilk. Chemosphere 43 (2001) 243-256
11. Harrison K. Too close to home: dioxin contamination of breast milk and political agenda. Policy Sci. 34 (2001) 35-62
12. Hesse V., Jaeger U., Vogel H., Kromeyer K., Zellner K., Bernhardt I., et al. Wachstumsdaten deutscher Kinder von Geburt bis zu 18 Jahren. Sozialpädiatrie 19 (1997) 20-22
13. Kreuzer P.E., Csanády G., Baur C., Kessler W., Päpke O., Greim H., and Filser J.G. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and congeners in infants. A toxicokinetic model of human lifetime body burden by TCDD with special emphasis on its uptake by nutrition. Arch. Toxicol. 71 (1997) 383-400
14. Kulhanek A., Trapp S., Sismilich M., Janků J., and Zimová M. Crop-specific human exposure assessment for polycyclic aromatic hydrocarbons in Czech soils. Sci. Total Environ. 339 (2005) 71-80
15. Layton D.W. Metabolically consistent breathing rates for use in dose assessments. Health Phys. 64 (1993) 23-26
16. Maruyama W., Yoshida K., Tanaka T., and Nakanishi J. Simulation of dioxin accumulation in human tissues and analysis of reproductive risk. Chemosphere 53 (2003) 301-313
17. McLachlan, M.S., 1992. Das Verhalten hydrophober chlororganischer Verbindungen in laktierenden Rindern [doctoral thesis]. University of Bayreuth, Germany.
18. Nazaroff W.N., and Alvarez-Cohen L. Environmental Engineering Science (2001), John Wiley & Sons, New York 624-625
19. Raab U., Schwegler U., Preiss U., Albrecht M., and Fromme H. Bavarian breast milk survey - pilot study and future developments. Int. J. Hyg. Environ. Health 210 (2007) 341-344
20. Rikken M.G.J., Lijzen J.P.A., and Cornelese A.A. Evaluation of Model Concepts on Human Exposure. Proposals for Updating the Most Relevant Exposure Routes of CSOIL. RIVM Report 711 701 022 (2001), Bilthoven, The Netherlands
21. Rippen G. Handbuch Umweltchemikalien. (permanently updated) (1990-2007), ecomed, Landsberg am Lech, D
22. Rogan W.J., Gladen B.C., McKinney J.D., Carreras N., Hardy P., Thullen J., et al. Polychlorinated biphenyls (PCB) and dichlorophenyl dichloroethane (DDE) in human milk: effects of maternal factors and previous lactation. Am. J. Public Health 76 (1986) 172-177
23. Schade G., and Heinzow B. Organochlorine pesticides and polychlorinated biphenyls in human milk of mothers living in northern Germany: current extent of contamination, time trend from 1986 to 1997 and factors that influence the levels of contamination. Sci. Total Environ. 215 (1998) 31-39
24. Schecter A., Päpke O., Lis A., Ball M., Ryan J.J., Olson J.R., et al. Decrease in milk and blood dioxin levels over two years in a mother nursing twins: estimates of decreased maternal and increased infant dioxin body burden from nursing. Chemosphere 32 (1996) 543-549
25. Shen H., Main K.H., Virtanen H.E., Damggard I.N., Haavisto A.-M., Kaleva M., Boisen K.A., Schmidt I.M., Chellakooty M., Skakebaek N.E., Toppari J., and Schramm K.-W. From mother to child: investigation of the prenatal and postnatal exposure to persistent bioaccumulating toxicants using breast milk and placenta biomonitoring. Chemosphere 67 (2007) S256-S262
26. Tanabe S., and Kunisue T. Persistent organic pollutants in human breast milk from Asian countries. Environ. Pollut. 146 (2007) 400-413
27. Trapp S. Plant uptake and transport models for neutral and ionic chemicals. Environ. Sci. Pollut. Res. 11 (2004) 33-39
28. Trapp S., and Horobin R.W. A predictive model for the selective accumulation of chemicals in tumor cells. Eur. Biophys. J. 34 (2005) 959-966
29. Travis C.C., Hattemer-Frey H.A., and Arms A.A. Relationship between dietary intake of organic chemicals and their concentrations in human adipose tissue and breast milk. Arch. Environ. Contam. Toxicol. 17 (1988) 473-478
30. Travis C.C., and Hattemeyer-Frey H.A. Human exposure to dioxin. Sci. Total Environ. 104 (1991) 97-127
31. UNEP (United Nations Environmental Program). Stockholm Convention on Persistent Organic Pollutants (POPs) (2007). http://www.pops.int/ (accessed 04.06.07)
32. US EPA (U.S. Environmental Protection Agency). Children's Environmental Health: 2006 Report. Environment, Health, and a Focus on Children (2006). http://yosemite.epa.gov/ochp/ochpweb.nsf/content/homepage.htm (accessed 04.07.07)
33. Van Der Molen G.W., Kooijman S.A.L.M., and Slob W. A generic toxicokinetic model for persistent lipophilic compounds in humans: an application to TCDD. Fundam. Appl. Toxicol. 31 (1996) 83-94
34. Wittsiepe J., Fürst P., Schrey P., Lemm F., Kraft M., Eberwein G., et al. PCDD/F and dioxin-like PCB in human blood and milk from German mothers. Chemosphere 67 (2007) S286-S294
35. Wuenschmann S., Fraenzle S., Markert B., and Zechmeister H. Input and transfer of trace metals from food via mothermilk to the child - bioindicative aspects to human health. In: Prasad M.N.V. (Ed). Trace Elements: Nutritional Benefits, Environmental Contamination, and Health Implications (2008), John Wiley and Sons, New York