Successful Incorporation of Tissue-Engineered Porcine Small-Intestinal Submucosa as Substitute Flexor Tendon Graft Is Mediated by Elevated TGF-β1 Expression in the Rabbit

Journal of Hand Surgery

Volumn 33, Issue 7, 2008, Pages 1168-1178

  Murphy, Kevin D ^a   Mushkudiani, Ioseb A ^a   Kao, Dennis ^a   Levesque, Andre Y ^a   Hawkins, Hal K ^a   Gould, Lisa J ^a  

^a ULSTER HOSPITAL   (United Kingdom)

Author keywords

Bioengineering; tendon grafts; tendon healing; tendon substitutes; TGF 1; tissue substitutes

Indexed keywords

COLLAGEN; EOSIN; HEMATOXYLIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FOREFOOT; FOREIGN BODY; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; INTESTINE MUCOSA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; SMALL INTESTINE; SWINE; TENDON GRAFT; TENSILE STRENGTH; TISSUE ENGINEERING; VASCULARIZATION;

ANIMALS; INTESTINAL MUCOSA; INTESTINE, SMALL; RABBITS; TENDON INJURIES; TENDONS; TENSILE STRENGTH; TISSUE ENGINEERING; TISSUE TRANSPLANTATION; TRANSFORMING GROWTH FACTOR BETA1; TRANSPLANTATION, AUTOLOGOUS; TRANSPLANTATION, HETEROLOGOUS; WOUND HEALING;

EID: 50549096827     PISSN: 03635023     EISSN: 15316564     Source Type: Journal    
DOI: 10.1016/j.jhsa.2008.02.003     Document Type: Article

References (24)

1. Badylak S.F., Tullius R., Kokini K., Shelbourne K.D., Klootwyk T., Voytiket S.L., et al. The use of xenogeneic small intestinal submucosa as a biomaterial for Achilles tendon repair in a dog model. J Biomed Mater Res 29 (1995) 977-985
2. Cobb M.A., Badylak S.F., Janas W., Simmons-Byrd A., and Boop F.A. Porcine small intestinal submucosa as a dural substitute. Surg Neurol 51 (1999) 99-104
3. Gu Y., and Dai K. Substitution of porcine small intestinal submucosa for rabbit Achilles tendon, an experimental study. Zhonghua Yi Xue Za Zhi 82 (2002) 1279-1282
4. Kim S.S., Kaihara S., Benvenuto M.S., Kim B.S., Mooney D.J., and Vacanti J.P. Small intestinal submucosa as a small-caliber venous graft: a novel model for hepatocyte transplantation on synthetic biodegradable polymer scaffolds with direct access to the portal venous system. J Pediatr Surg 34 (1999) 124-128
5. Nuininga J.E., van Moerkerk H., Hanssen A., Hulsbergen C.A., Oosterwijk-Wakka J., Oosterwijk E., et al. Rabbit urethra replacement with a defined biomatrix or small intestinal submucosa. Eur Urol 44 (2003) 266-271
6. Ngo M., Pham H., Longaker M.T., and Chang J. Differential expression of transforming growth factor-beta receptors in a rabbit zone II flexor tendon wound healing model. Plast Reconstr Surg 108 (2001) 1260-1267
7. Chang J., Most D., Stelnicki E., Siebert J.W., Longaker M.T., Hui K., et al. Gene expression of transforming growth factor beta-1 in rabbit zone II flexor tendon wound healing: evidence for dual mechanisms of repair. Plast Reconstr Surg 100 (1997) 937-944
8. Gelberman R.H., Manske P.R., Vande Berg J.S., Lesker P.A., and Akeson W.H. Flexor tendon repair in vitro: a comparative histologic study of the rabbit, chicken, dog, and monkey. J Orthop Res 2 (1984) 39-48
9. Lundborg G., Rank F., and Heinau B. Intrinsic tendon healing. A new experimental model. Scand J Plast Reconstr Surg 19 (1985) 113-117
10. Malaviya P., Butler D.L., Boivin G.P., Smith F.N., Barry F.P., Murphy J.M., et al. An in vivo model for load-modulated remodeling in the rabbit flexor tendon. J Orthop Res 18 (2000) 116-125
11. Malaviya P., Butler D.L., Korvick D.L., and Proch F.S. In vivo tendon forces correlate with activity level and remain bounded: evidence in a rabbit flexor tendon model. J Biomech 31 (1998) 1043-1049
12. Reddy G.K., and Enwemeka C.S. A simplified method for the analysis of hydroxyproline in biological tissues. Clin Biochem 29 (1996) 225-229
13. Boyes J.H. Evaluation of results of digital flexor tendon graft. Am J Surg 89 (1955) 1116-1119
14. McDevitt C.A., Wildey G.M., and Cutrone R.M. Transforming growth factor-beta1 in a sterilized tissue derived from the pig small intestine submucosa. J Biomed Mater Res A 67 (2003) 637-640
15. Voytik-Harbin S.L., Brightman A.O., Kraine M.R., Waisner B., and Badylak S.F. Identification of extractable growth factors from small intestinal submucosa. J Cell Biochem 67 (1997) 478-491
16. Ansaloni L., Catena F., and D'Alessandro L. Prospective randomized, double-blind, controlled trial comparing Lichtenstein's repair of inguinal hernia with polypropylene mesh versus Surgisis gold soft tissue graft: preliminary results. Acta Biomed 74 Suppl 2 (2003) 10-14
17. Franklin Jr. M.E., Gonzalez Jr. J.J., and Glass J.L. Use of porcine small intestinal submucosa as a prosthetic device for laparoscopic repair of hernias in contaminated fields: 2-year follow-up. Hernia 8 (2004) 186-189
18. Oelschlager B.K., Barreca M., Chang L., and Pellegrini C.A. The use of small intestine submucosa in the repair of paraesophageal hernias: initial observations of a new technique. Am J Surg 186 (2003) 4-8
19. Franklin Jr. M.E., Gonzalez Jr. J.J., Michaelson R.P., Glass J.L., and Chock D.A. Preliminary experience with new bioactive prosthetic material for repair of hernias in infected fields. Hernia 6 (2002) 171-174
20. Ambro B.T., Zimmerman J., Rosenthal M., and Pribitkin E.A. Nasal septal perforation repair with porcine small intestinal submucosa. Arch Facial Plast Surg 5 (2003) 528-529
21. Struck H. Immunological investigations of antigenicity and specificity of soluble collagen fractions. IV. Anaphylaxis and allergy experiments. Eur Surg Res 8 (1976) 243-249
22. Supp D.M., and Boyce S.T. Engineered skin substitutes: practices and potentials. Clin Dermatol 23 (2005) 403-412
23. Small J.O., Brennen M.D., and Colville J. Early active mobilization following flexor tendon repair in Zone 2. J Hand Surg 14B (1989) 383-391
24. Cullen K.W., Tolhurst P., Land D., and Page R.E. Flexor tendon repair in zone 2 followed by controlled active mobilization. J Hand Surg 14B (1989) 392-395