Bioactive peptides derived from the Limulus anti-lipopolysaccharide factor: Structure-activity relationships and formation of mixed peptide/lipid complexes

Journal of Peptide Science

Volumn 14, Issue 8, 2008, Pages 963-971

  Mora, Puig ^a   de la Paz, Manuela López ^b   Pérez Payá, Enrique ^a,c  

^a CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

Author keywords

Bioactive peptides; Endotoxin; LALF; Lipid A; LPS; Molecular recognition; Sepsis; Septic shock

Indexed keywords

CYCLOPEPTIDE; LIMULUS ANTILIPOPOLYSACCHARIDE FACTOR; LIMULUS ANTILIPOPOLYSACCHARIDE FACTOR 14; LIMULUS ANTILIPOPOLYSACCHARIDE FACTOR 40; LIMULUS ANTILIPOPOLYSACCHARIDE FACTOR 41; LIMULUS ANTILIPOPOLYSACCHARIDE FACTOR 42; LIMULUS ANTILIPOPOLYSACCHARIDE FACTOR 43; LIMULUS ANTILIPOPOLYSACCHARIDE FACTOR 44; LIMULUS ANTILIPOPOLYSACCHARIDE FACTOR F39A; LIMULUS ANTILIPOPOLYSACCHARIDE FACTOR K43A; LIMULUS ANTILIPOPOLYSACCHARIDE FACTOR K45A; LIMULUS ANTILIPOPOLYSACCHARIDE FACTOR K47A; LIMULUS ANTILIPOPOLYSACCHARIDE FACTOR L42A; LIMULUS ANTILIPOPOLYSACCHARIDE FACTOR R40A; LIMULUS ANTILIPOPOLYSACCHARIDE FACTOR R41A; LIMULUS ANTILIPOPOLYSACCHARIDE FACTOR W44A; LIMULUS ANTILIPOPOLYSACCHARIDE FACTOR Y46A; LIPID; LIPOPOLYSACCHARIDE; PEPTIDE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG BINDING; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENCE SPECTROSCOPY; IN VITRO STUDY; LIMULUS; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN INTERACTION; SEPTIC SHOCK; STRUCTURE ACTIVITY RELATION;

AMINO ACID SUBSTITUTION; ANIMALS; CELL MEMBRANE; CIRCULAR DICHROISM; DISEASE MODELS, ANIMAL; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; ENDOTOXEMIA; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT DYES; INJECTIONS, INTRAPERITONEAL; INVERTEBRATE HORMONES; LIPIDS; LIPOPOLYSACCHARIDES; MACROMOLECULAR SUBSTANCES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED BALB C; MODELS, MOLECULAR; PEPTIDES, CYCLIC; SOLUTIONS; SPECTROMETRY, FLUORESCENCE; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR NECROSIS FACTOR-ALPHA;

BACTERIA (MICROORGANISMS); LIMULUS;

EID: 50449111197     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.1033     Document Type: Article

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