Neurogenetic networks for startle-induced locomotion in Drosophila melanogaster

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 34, 2008, Pages 12393-12398

  Yamamoto, Akihiko ^a   Zwarts, Liesbeth ^b   Callaerts, Patrick ^b   Norga, Koenraad ^b   Mackay, Trudy F C ^a   Anholt, Robert R H ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Behavioral genetics; Epistasis; p element insertional mutagenesis; Sensorimotor integration; Startle behavior

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; FEMALE; GENE; HETEROZYGOTE; LOCOMOTION; MALE; MUTANT; MUTATION; NEUROANATOMY; NONHUMAN; PRIORITY JOURNAL; STARTLE REFLEX; TRANSPOSON;

ANIMALS; DNA TRANSPOSABLE ELEMENTS; DROSOPHILA MELANOGASTER; EPISTASIS, GENETIC; GENE REGULATORY NETWORKS; LOCOMOTION; MUTATION; NERVOUS SYSTEM PHYSIOLOGY; STARTLE REACTION;

DROSOPHILA MELANOGASTER;

EID: 50449085759     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0804889105     Document Type: Article

References (48)

1. Anholt RRH (2004) Genetic modules and networks for behavior: Lessons from Drosophila. BioEssays 26:1299-1306.
2. Anholt RRH, Mackay TFC (2004) Quantitative genetic analyses of complex behaviours in Drosophila. Nat Rev Genet 5:838-849.
3. Edwards AC, Rollmann SM, Morgan TJ, Mackay TFC (2006) Quantitative genomics of aggressive behavior in Drosophila melanogaster. PLoS Genet 2:e154.
4. Morozova TV, Anholt RRH, Mackay TFC (2007) Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaster. Genome Biol 8:R231.
5. Jordan KW, Carbone MA, Yamamoto A, Morgan TJ, Mackay TFC (2007) Quantitative genomics of locomotor behavior in Drosophila melanogaster. Genome Biol 8:R172.
6. Mackay TFC, et al. (2005) Genetics and genomics of Drosophila mating behavior. Proc Natl Acad Sci USA 102:6622-6629.
7. Toma DP, White KP, Hirsch J, Greenspan RJ (2002) Identification of genes involved in Drosophila melanogaster geotaxis, a complex behavioral trait. Nat Genet 31:349-353.
8. Dierick HA, Greenspan RJ (2006) Molecular analysis of flies selected for aggressive behavior. Nat Genet 38:1023-1031.
9. Daniels GM, Buck KJ (2002) Expression profiling identified strain-specific changes associated with ethanol withdrawal in mice. Genes Brain Behav 1:35-45.
10. Worst TJ, et al. (2005) Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. J Neurosci Res 80:529-538.
11. Jordan KW, Morgan TJ, Mackay TFC (2006) Quantitative trait loci for locomotor behavior in Drosophila melanogaster. Genetics 174:271-284.
12. Carbone MA, et al. (2006) Phenotypic variation and natural selection at catsup, a pleiotropic quantitative trait gene in Drosophila. Curr Biol 16:912-919.
13. Leal SM, Kumar N, Neckameyer WS (2004) GABAergic modulation of motor-driven behaviors in juvenile Drosophila and evidence for a nonbehavioral role for GABA transport. J Neurobiol 61:189-208.
14. Fox LE, Soll DR, Wu CF (2006) Coordination and modulation of locomotion pattern generators in Drosophila larvae: Effects of altered biogenic amine levels by the tyramine beta hydroxylase mutation. J Neurosci 26:1486-1498.
15. Hardie SL, Zhang JX, Hirsh J (2007) Trace amines differentially regulate adult locomotor activity, cocaine sensitivity, and female fertility in Drosophila melanogaster. Dev Neurobiol 67:1396-1405.
16. Nichols CD (2007) 5-HT2 receptors in Drosophila are expressed in the brain and modulate aspects of circadian behaviors. Dev Neurobiol 67:752-763.
17. Seeger M, Tear G, Ferres-Marco D, Goodman CS (1993) Mutations affecting growth cone guidance in Drosophila: Genes necessary for guidance toward or away from the midline. Neuron 10:409-426.
18. Kidd T, et al. (1998) Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors. Cell 92:205-215.
19. Tsai LT, Bainton RJ, Blau J, Heberlein U (2004) Lmo mutants reveal a novel role for circadian pacemaker neurons in cocaine-induced behaviors. PLoS Biol 2:e408.
20. Rollmann SM, et al. (2008) Pleiotropic effects of Drosophila neuralized on complex behaviors and brain structure. Genetics in press.
21. Rollmann SM, et al. (2007) The early developmental gene Semaphorin 5c contributes to olfactory behavior in adult Drosophila. Genetics 176:947-956.
22. Lyman RF, Lawrence F, Nuzhdin SV, Mackay TFC (1996) Effects of single P-element insertions on bristle number and viability in Drosophila melanogaster. Genetics 143:277-292.
23. Fedorowicz GM, Fry JD, Anholt RRH, Mackay TFC (1998) Epistatic interactions between smell-impaired loci in Drosophila melanogaster. Genetics 148:1885-1891.
24. Sambandan D, Yamamoto A, Fanara JJ, Mackay TFC, Anholt RRH (2006) Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster. Genetics 174:1349-1363.
25. van Swinderen B, Greenspan RJ (2005) Flexibility in a gene network affecting a simple behavior in Drosophila melanogaster. Genetics 169:2151-2163.
26. Griffing B (1956) Concept of general and specific combining ability in relation to diallel crossing systems. Aust J Biol Sci 9:463-493.
27. Giniger E, Tietje K, Jan LY, Jan YN (1994) lola encodes a putative transcription factor required for axon growth and guidance in Drosophila. Development 120:1385-1398.
28. Crowner D, Madden K, Goeke S, Giniger E (2002) Lola regulates midline crossing of CNS axons in Drosophila. Development 129:1317-1325.
29. Cayirlioglu P, et al. (2008) Hybrid neurons in a microRNA mutant are putative evolutionary intermediates in insect CO2 sensory systems. Science 319:1256-1260.
30. Li X, Carthew RW (2005) A microRNA mediates EGF receptor signaling and promotes photoreceptor differentiation in the Drosophila eye. Cell 123:1267-1277.
31. Yi R, et al. (2006) Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs. Nat Genet 38:356-362.
32. Plasterk RH (2006) MicroRNAs in animal development. Cell 124:877-881.
33. Choi PS, et al. (2008) Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron 57:41-55.
34. Rajewski N, Socci ND (2004) Computational identification of microRNAs targets. Dev Biol 267:529-535.
35. Hirth F, et al. (1995) Developmental defects in brain segmentation caused by mutations of the homeobox genes orthodenticle and empty spiracles in Drosophila. Neuron 15:769-778.
36. Davis RL (2005) Olfactory memory formation in Drosophila: From molecular to systems neuroscience. Annu Rev Neurosci 28:275-302.
37. Margulies C, Tully T, Dubnau J (2005) Deconstructing memory in Drosophila. Curr Biol 15:R700-R713.
38. Martin JR, Ernst R, Heisenberg M (1998) Mushroom bodies suppress locomotor activity in Drosophila melanogaster. Learning & Memory 5:179-191.
39. Helfrich-Förster C, Wulf J, de Belle JS (2002) Mushroom body influence on locomotor activity and circadian rhythms in Drosophila melanogaster. J Neurogenet 16:73-109.
40. Strauss R, Heisenberg M (1993) A higher control center of locomotor activity in the Drosophila brain. J Neurosci 13:1852-1861.
41. Strauss R (2002) The central complex and the genetic dissection of locomotor behaviour. Curr Opin Neurobiol 12: 633-638.
42. Norga KK, et al. (2003) Quantitative analysis of bristle number in Drosophila mutants identifies genes involved in neural development. Curr Biol 13:1388-1396.
43. Anholt RRH, et al. (2003) The genetic architecture of odor-guided behavior in Drosophila: Epistasis and the transcriptome. Nat Genet 35:180-184.
44. Kraut R, Menon K, Zinn K (2001) A gain-of-function screen for genes controlling motor axon guidance and synaptogenesis in Drosophila. Curr Biol 11:417-430.
45. Madden K, Crowner D, Giniger E (1999) lola has the properties of a master regulator of axon-target interaction for SNb motor axons of Drosophila. Dev Biol 213:301-313.
46. Yu HH, Araj HH, Ralls SA, Kolodkin AL (1998) The transmembrane Semaphorin Sema I is required in Drosophila for embryonic motor and CNS axon guidance. Neuron 20:207-220.
47. Lukacsovich T, et al. (2001) Dual-tagging gene trap of novel genes in Drosophila melanogaster. Genetics 157:727-742.
48. Bellen HJ, et al. (2004) The BDGP gene disruption project: Single transposon insertions associated with 40% of Drosophila genes. Genetics 167:761-781.