Flow-induced permeation of non-occlusive blood clots: An MRI study and modelling

European Biophysics Journal

Volumn 37, Issue 7, 2008, Pages 1229-1233

  Grobelnik, Barbara ^a   Vidmar, Jernej ^a   Tratar, Gregor ^b   Blinc, Aleš ^b   Serša, Igor ^a  

^a JO EF STEFAN INSTITUTE   (Slovenia)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

Dynamical MRI; Flow; Mathematical modelling; Non occlusive blood clot; Permeation; Thrombolysis

Indexed keywords

BLOOD CLOT; BLOOD CLOT LYSIS; BLOOD CLOT RETRACTION; CONFERENCE PAPER; FIBRINOLYTIC THERAPY; FLOW KINETICS; IMAGE ANALYSIS; MATHEMATICAL MODEL; NUCLEAR MAGNETIC RESONANCE IMAGING; PERMEABILITY; POROSITY;

BLOOD COAGULATION; CONTRAST MEDIA; CORONARY OCCLUSION; GADOLINIUM DTPA; MAGNETIC RESONANCE IMAGING; MODELS, BIOLOGICAL; PERMEABILITY; THROMBOLYTIC THERAPY; TIME FACTORS;

EID: 50449085691     PISSN: 01757571     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00249-008-0342-8     Document Type: Conference Paper

References (15)

1. K Kandarpa 1999 Catheter-directed thrombolysis of peripheral arterial occlusions and deep vein thrombosis Thromb Haemost 82 987 996
2. A Blinc CW Francis 1996 Transport processes in fibrinolysis and fibrinolytic therapy Thromb Haemost 76 481 491
3. ME Carr Jr LL Shen J Hermans 1977 Mass-length ratio of fibrin fibers from gel permeation and light scattering Biopolymers 16 1 15
4. D Collen 1999 The plasminogen (fibrinolytic) system Thromb Haemost 82 259 270
5. J Hennig A Nauerth H Friedburg 1986 RARE imaging: a fast imaging method for clinical MR Magn Reson Med 3 823 833
6. N Kucher SZ Goldhaber 2006 Risk stratification of acute pulmonary embolism Semin Thromb Hemost 32 838 847
7. Landau LD, Lifshitz EM (1995) Fluid mechanics, 2nd edn. Butterworth-Heinemann, Oxford
8. Nichols WW, McDonald DA, O'Rourke MF (2005) McDonald's blood flow in arteries: theoretical, experimental, and clinical principles, 5th edn. Hodder Arnold; distributed in the United States of America by Oxford University Press, New York
9. CP Pleydell T David SW Smye DC Berridge 2002 A mathematical model of post-canalization thrombolysis Phys Med Biol 47 209 224
10. DV Sakharov DC Rijken 2000 The effect of flow on lysis of plasma clots in a plasma environment Thromb Haemost 83 469 474
11. I Sersa G Tratar U Mikac A Blinc 2007 A mathematical model for the dissolution of non-occlusive blood clots in fast tangential blood flow Biorheology 44 1 16
12. I Sersa J Vidmar B Grobelnik U Mikac G Tratar A Blinc 2007 Modelling the effect of laminar axially directed blood flow on the dissolution of non-occlusive blood clots Phys Med Biol 52 2969 2985
13. G Tratar A Blinc M Strukelj U Mikac I Sersa 2004 Turbulent axially directed flow of plasma containing rt-PA promotes thrombolysis of non-occlusive whole blood clots in vitro Thromb Haemost 91 487 496
14. SR White-Bateman HC Schumacher RL Sacco PS Appelbaum 2007 Consent for intravenous thrombolysis in acute stroke: review and future directions Arch Neurol 64 785 792
15. DM Wootton AS Popel BR Alevriadou 2002 An experimental and theoretical study on the dissolution of mural fibrin clots by tissue-type plasminogen activator Biotechnol Bioeng 77 405 419