Leukocytoclastic vasculitis associated with tumor necrosis factor-α blocking agents

Journal of Rheumatology

Volumn 31, Issue 10, 2004, Pages 1955-1958

  Mohan, Niveditha ^a,d   Edwards, Evelyne T ^b   Cupps, Thomas R ^c   Slifman, Nancy ^b   Lee, Jong Hoon ^b   Siegel, Jeffrey N ^b   Braun, M Miles ^b  

^a UNIVERSITY OF SOUTH DAKOTA   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^d Avera Research Institute   (United States)

Author keywords

Etanercept; Infliximab; Leukocytoclastic vasculitis; Tumor necrosis factor blockers

Indexed keywords

ANTIHISTAMINIC AGENT; AZATHIOPRINE; ETANERCEPT; FUROSEMIDE; GLUCOCORTICOID; INFLIXIMAB; LISINOPRIL; LOSARTAN; METHOTREXATE; NAPROXEN; PREDNISONE; QUININE; SALAZOSULFAPYRIDINE; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ABDOMINAL PAIN; ADOLESCENT; ADULT; AGED; ANKYLOSING SPONDYLITIS; ARTHRALGIA; ARTICLE; BLISTER; CEREBROVASCULAR ACCIDENT; CLINICAL ARTICLE; CROHN DISEASE; DRUG SURVEILLANCE PROGRAM; EDEMA; FATIGUE; FEMALE; FEVER; FOOD AND DRUG ADMINISTRATION; HEMATURIA; HUMAN; JUVENILE RHEUMATOID ARTHRITIS; LEUKOCYTOCLASTIC VASCULITIS; MALAISE; MALE; MYALGIA; PERICARDIAL EFFUSION; PERIPHERAL NEUROPATHY; PETECHIA; PLEURISY; PRIORITY JOURNAL; PSORIATIC ARTHRITIS; RHEUMATOID ARTHRITIS; SKIN NODULE; URTICARIA;

ADOLESCENT; ADULT; ADVERSE DRUG REACTION REPORTING SYSTEMS; AGED; ANTIBODIES, MONOCLONAL; ANTIRHEUMATIC AGENTS; FEMALE; HUMANS; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; RECEPTORS, TUMOR NECROSIS FACTOR; RECOMBINANT FUSION PROTEINS; RHEUMATIC DISEASES; TUMOR NECROSIS FACTOR-ALPHA; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION; VASCULITIS, HYPERSENSITIVITY;

EID: 5044237150     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Mori L, Iselin S, De Libero G, Lesslauer W. Attenuation of collagen-induced arthritis in 55-kDa TNF receptor type (TNFR1)-IgG1-treated and TNFR1-deficient mice. J Immunol 1996;157:3178-82.
2. Moreland LW, Baumgartner SW, Schiff MH, et al. Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N Engl J Med 1997;337:141-7.
3. Elliott MJ, Maini RN, Feldmann M, et al. Randomized double-blind comparison of chimeric monoclonal antibody to tumor necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis. Lancet 1994;344:1105-10.
4. Brandt J, Haibel H, Cornely D, et al. Successful treatment of active ankylosing spondylitis with the anti-tumor necrosis factor alpha monoclonal antibody infliximab. Arthritis Rheum 2000;43:1346-52.
5. Chaudhari U, Romano P, Mulcahy LD, Dooley LT, Baker DG, Gottlieb AB. Efficacy and safety of infliximab monotherapy for plaque-type psoriasis: a randomized trial. Lancet 2001;357:1842-7.
6. Goossens PH, Verburg RJ, Breedveld FC. Remission of Behcet's syndrome with tumor necrosis factor alpha blocking therapy. Ann Rheum Dis 2001;60:637.
7. Targan SR, Hanauer SB, van Deventer SJ, et al. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. N Engl J Med 1997;337:1029-35.
8. Present DH, Rutgeerts P, Targan S, et al. Infliximab for the treatment of fistulas in patients with Crohn's disease. N Engl J Med 1999;340:1398-405.
9. Galaria NA, Werth VP, Schumacher HR. Leukocytoclastic vasculitis due to etanercept. J Rheumatol 2000;27:2041-4.
10. Brion PH, Mittal-Henkle A, Kalunian KC. Autoimmune skin rashes associated with etanercept for rheumatoid arthritis [letter]. Ann Intern Med 1999;131:634.
11. Smolen JS, Steiner G, Breedveld FC, et al. Anti-TNFa therapy and drug-induced lupus-like syndrome [abstract]. Ann Rheum Dis 1999;50 Suppl:128.
12. Jennette JC, Falk RJ. Small-vessel vasculitis. New Engl J Med 1997;337:1512-23.
13. Koutkia P, Mylonakis E, Rounds S, Erickson A. Leukocytoclastic vasculitis: an update for the clinician. Scand J Rheumatol 2001;30:315-22.
14. Halevy S, Giryes H, Avinoach I, Livni E, Sukenik S. Leukocytoclastic vasculitis induced by low-dose methotrexate: in vitro evidence for an immunologic mechanism. J Eur Acad Dermatol Venereol 1998;10:81-5.
15. Simonart T, Durez P, Margaux J, Van Geertruyden J, Goldschmidt D, Parent D. Cutaneous necrotizing vasculitis after low dose methotrexate therapy for rheumatoid arthritis: a possible manifestation of methotrexate hypersensitivity. Clin Rheumatol 1997;16:623-5.
16. Laversuch CJ, Collins DA, Charles PJ, Bourke BE. Sulphasalazine-induced autoimmune abnormalities in patients with rheumatic disease. Br J Rheumatol 1995;34:435-9.
17. Knowles SR, Gupta AK, Shear NH, Sauder D. Azathioprine hypersensitivity-like reactions - a case report and review of the literature. Clin Exp Dermatol 1995;20:353-6.
18. Price EJ, Bevan JS, Rees A. Quinine-induced cutaneous vasculitis. Br J Clin Pract 1992;46:138-9.
19. Disdier P, Harle JR, Verrot D, Jouglard J, Weiller PJ. Adult Schonlein-Henoch purpura after lisinopril [letter]. Lancet 1992;340:985.
20. Bosch X. Henoch-Schonlein purpura induced by losartan therapy. Arch Intern Med 1998;158:191-2.
21. Lin RY. Unusual autoimmune manifestations in furosemide-associated hypersensitivity angiitis. NY State J Med 1988;88:439-40.
22. Schapira D, Balbir-Gurman A, Nahir AM. Naproxen-induced leukocytoclastic vasculitis. Clin Rheumatol 2000;19:242-4.
23. Turesson C, O'Fallon WM, Crowson CS, Gabriel SE, Malteson EL. Occurrence of extraarticular disease manifestations is associated with excess mortality in a community-based cohort of patients with rheumatoid arthritis. J Rheumatol 2002;29:62-7.
24. McCain ME, Quinet RJ, Davis WE. Etanercept and infliximab associated with cutaneous vasculitis. Rheumatology Oxford 2002;41:116-7.
25. Mohan AK, Edwards ET, Cote TR, Siegel JN, Braun MM. Drug-induced systemic lupus erythematosus and TNF-alpha blockers [letter]. Lancet 2002;360:646.
26. Weinblatt ME, Kremer JM, Bankhurst AD, et al. A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate. N Engl J Med 1999;340:253-9.
27. Claudy A. Pathogenesis of leukocytoclastic vasculitis. Eur J Dermatol 1998;8:75-9.
28. Roujeau JC, Stem RS. Severe adverse cutaneous reactions to drugs. N Engl J Med 1994;10:1272-85.