Treating heparin-induced thrombocytopenia. The unconventional way!

Saudi Medical Journal

Volumn 25, Issue 9, 2004, Pages 1258-1260

  Abdel Razeq, Hikmat N ^a   Bajouda, Ali A ^a   Khalil, Manar M ^a   Ashmeg, Abdullah K ^a  

^a KING FAHD ARMED FORCES HOSPITAL   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALBUMIN; ARGATROBAN; DANAPAROID; FRESH FROZEN PLASMA; GLYCERYL TRINITRATE; HEPARIN; IMMUNOGLOBULIN; LEPIRUDIN; LOW MOLECULAR WEIGHT HEPARIN; THROMBIN INHIBITOR; WARFARIN;

ADULT; ANTICOAGULATION; ARTERY THROMBOSIS; ARTICLE; CASE REPORT; DISEASE SEVERITY; DRUG WITHDRAWAL; FEMALE; GANGRENE; HEART INFARCTION; HEPARINIZATION; HUMAN; LIMB ISCHEMIA; OCCLUSIVE CEREBROVASCULAR DISEASE; PLASMAPHERESIS; SKIN NECROSIS; THROMBOCYTOPENIA; VEIN THROMBOSIS;

FEMALE; FIBRINOLYTIC AGENTS; FOLLOW-UP STUDIES; HEPARIN; HUMANS; MIDDLE AGED; MYOCARDIAL INFARCTION; PLASMAPHERESIS; RISK ASSESSMENT; SAUDI ARABIA; SEVERITY OF ILLNESS INDEX; THROMBOCYTOPENIA; TREATMENT OUTCOME;

EID: 5044235579     PISSN: 03795284     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Warkentin TE, Chong BH, Greinacher A. Heparin-induced thrombocytopenia: toward consensus. Thromb Haemost 1998; 79: 1-7.
2. Warkentin TE. Heparin-induced thrombocytopenia: pathogenesis, frequency, avoidance and management. Drug Saf 1997; 17: 325-341.
3. Warkentin TE. Venous thromboembolism in heparin-induced thrombocytopenia. Curr Opin Pulm Med 2000; 6: 343-351.
4. Warkentin TE, Sheppard JA, Horsewood P, Simpson PJ, Moore JC, Kelton JG. Impact of the patient population on the risk for heparin-induced thrombocytopenia. Blood 2000; 96: 1703-1708.
5. Greinacher A, Eichler P, Lubenow N, Kwasny H, Luz M. Heparin-induced thrombocytopenia with thromboembolic complication: meta-analysis of two prospective trials to assess the value of parenteral treatment with lepuridin and its therapeutic aPTT range. Blood 2000; 96: 846-851.
6. Greinacher A, Potzsch B, Amiral J, Dummel V, Eichner A, Mueller-Eckhardt C. Heparin-associated thrombocytopenia: isolation of the antibody & characterization of a multi molecular PF4-heparin complex as the major antigen. Thromb Haemost 1994; 71: 247-251.
7. Warkentin TE, Elavathil LJ, Hayward CP, Johnston MA, Russett JI, Kelton JG. The pathogenesis of venous limb gangrene associated with heparin-induced thrombocytopenia. Ann Intern Med 1997; 127: 804-812.
8. Hirsh J, Warkentin TE, Shaughnessy SG, Anand SS, Halperin JL, Raschke R et al. Heparin and low-molecular weight heparin. Mechanism of action, pharmacokinetic, dosing, monitoring, efficacy and safety. Chest 2001; 119: 64S-94S.
9. Alving BM. How I treat heparin-induced thrombocytopenia and thrombosis. Blood 2003; 101: 31-37.
10. Cohen JI, Cooper MR, Greenberg CS. Streptokinase therapy of pulmonary emboli with heparin-associated thrombocytopenia. Arch Intern Med 1985; 145: 1725-1726.
11. Robinson JA, Lewis BE. Plasmapheresis in the management of heparin-induced thrombocytopenia. Semin Hematol 1999; 36 Suppl 1: 29-32.