Massive vulval edema secondary to obesity and immobilization: A potential mimic of aggressive angiomyxoma

International Journal of Gynecological Pathology

Volumn 27, Issue 3, 2008, Pages 447-452

  McCluggage, W Glenn ^a   Nielsen, G P ^b   Young, Robert H ^b  

^a ROYAL GROUP OF HOSPITALS TRUST   (United Kingdom)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Edema; Vulva

Indexed keywords

ESTROGEN RECEPTOR;

ADIPOSE TISSUE; ADULT; AGED; AGGRESSIVE ANGIOMYXOMA; ANAMNESIS; ARTICLE; CASE REPORT; CLINICAL FEATURE; CONNECTIVE TISSUE; EDEMA; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMOBILIZATION; LYMPH VESSEL; LYMPHEDEMA; LYMPHOID CELL; MYXOMA; OBESITY; PLASMA CELL; PRIORITY JOURNAL; VULVAL EDEMA; WHEELCHAIR; VULVA DISEASE;

ADULT; EDEMA; FEMALE; HUMANS; IMMOBILIZATION; OBESITY; VULVAR DISEASES;

EID: 50349100197     PISSN: 02771691     EISSN: None     Source Type: Journal    
DOI: 10.1097/PGP.0b013e31816017a7     Document Type: Article

References (22)

1. McCluggage WG. A review and update of morphologically bland vulvovaginal mesenchymal lesions. Int J Gynecol Pathol 2005;24:26-38.
2. Nielsen GP, Young RH. Mesenchymal tumors and tumor-like lesions of the female genital tract: a selective review with emphasis on recently described entities. Int J Gynecol Pathol 2001;20:105-127
3. Steeper TA, Rosai J. Aggressive angiomyxoma of the female pelvis and perineum: report of nine cases of a distinctive type of gynecologic soft tissue neoplasm. Am J Surg Pathol 1983;7:463-475
4. Fetsch JF, Laskin WB, Lefkowitz M, et al. Aggressive angiomyxoma: a clinicopathologic study of 29 female patients. Cancer 1996;78:79-90. (Pubitemid 26189908)
5. Granter SR, Nucci MR, Fletcher CDM. Aggressive angiomyxoma: reappraisal of its relationship to angiomyofibroblastoma in a series of 16 cases. Histopathology 1997;30:3-10.
6. McCluggage WG, Patterson A, Maxwell P. Aggressive angiomyxoma of pelvic parts exhibits oestrogen and progesterone receptor positivity. J Clin Pathol 2000;53:603-605 (Pubitemid 30640171)
7. Ganesan R, McCluggage WG, Hirshowitz L, et al. Superficial myofibroblastoma of the lower female genital tract: report of a series including tumours with a vulval location. Histopathology 2005;46:137-143 (Pubitemid 40293011)
8. McCluggage WG, Ganesan R, Hirschowitz L, et al. Cellular angiofibroma and related fibromatous lesions of the vulva: report of a series of cases with a morphological spectrum wider than previously described. Histopathology 2004;45:360-368 (Pubitemid 39430641)
9. Fletcher CDM, Tsang WY, Fisher C, et al. Angiomyofibroblastoma of the vulva. A benign neoplasm distinct from aggressive angiomyxoma. Am J Surg Pathol 1992;16:373-382
10. Nielsen GP, Rosenberg AE, Koerner FC, et al. Smooth-muscle tumors of the vulva. A clinicopathologic study of 25 cases and review of the literature. Am J Surg Pathol 1996;20:779-793 (Pubitemid 26230741)
11. Laskin WB, Fetsch JF, Tavassoli FA. Superficial cervicovaginal myofibroblastoma: fourteen cases of a distinctive mesenchymal tumor arising from the specialized subepithelial stroma of the lower female genital tract. Hum Pathol 2001;32:715-725
12. Vang R, Connelly JH, Hammill HA, et al. Vulvar hypertrophy with lymphedema. A mimicker of aggressive angiomyxoma. Arch Pathol Lab Med 2000;124:1697-1699
13. Farshid G, Weiss S. Massive localized lymphedema in the morbidly obese: a histologically distinct reactive lesion simulating liposarcoma. Am J Surg Pathol 1998;22:1277-1283 (Pubitemid 28462776)
14. MacLean AB, Nicol LA, Hodgins MB. Immunohistochemical localization of estrogen receptors in the vulva and vagina. J Reprod Med 1990;35:1015-1016
15. Varnholt H, Otis CN, Nucci MR, et al. Fallopian tube prolapse mimicking aggressive angiomyxoma. Int J Gynecol Pathol 2005;24:292-294 (Pubitemid 40885085)
16. Nucci MR, Young RH, Fletcher CDM. Cellular pseudosarcomatous fibroepithelial stromal polyps of the lower female genital tract: an underrecognized lesion often misdiagnosed as sarcoma. Am J Surg Pathol 2000;24:231-240
17. Ostor AG, Fortune DW, Riley CB. Fibroepithelial polyps with atypical stromal cells (pseudosarcoma botryoides) of vulva and vagina. A report of 13 cases. Int J Gynecol Pathol 1988;7:351-360
18. Iwasa Y, Fletcher CD. Distinctive prepubertal vulval fibroma: a hitherto unrecognised mesenchymal tumor of prepubertal girls: analysis of 11 cases. Am J Surg Pathol 2004;28:1601-1608 (Pubitemid 39564965)
19. Vargas SO, Kozakewich HP, Boyd TK, et al. Childhood asymmetric labium majus enlargement mimicking a neoplasm. Am J Surg Pathol 2005;29:1007-1016
20. Humphries D. Unilateral vulval hypertrophy in competitive female cyclists. Br J Sports Med 2002;36:463-464 (Pubitemid 35454466)
21. Scanlon R, Kelehan P, Flannelly G, et al. Ischemic fasciitis: an unusual vulvovaginal spindle cell lesion. Int J Gynecol Pathol 2004;23:65-67 (Pubitemid 38018240)
22. Perosio PM, Weiss SW. Ischemic fasciitis: a juxtaskeletal fibroblastic proliferation with a predilection for elderly females. Mod Pathol 1993;6:69-72.