200th Anniversary of lactate research in muscle

Exercise and Sport Sciences Reviews

Volumn 36, Issue 3, 2008, Pages 109-115

  Gladden, L Bruce ^a  

^a AUBURN UNIVERSITY   (United States)

Author keywords

History; Intracellular lactate shuttle; Isozymes; Lactate dehydrogenase; Lactic dehydrogenase

Indexed keywords

ISOENZYME; LACTATE DEHYDROGENASE; LACTIC ACID;

ACIDOSIS; CELLULAR DISTRIBUTION; EXERCISE; HUMAN; MITOCHONDRIAL MEMBRANE; MUSCLE FATIGUE; MUSCLE METABOLISM; MUSCLE MITOCHONDRION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; REVIEW; ARTICLE; HISTORY; INTRACELLULAR SPACE; METABOLISM; PHYSIOLOGY; RESEARCH; SKELETAL MUSCLE;

EXERCISE; HISTORY, 18TH CENTURY; HISTORY, 19TH CENTURY; HISTORY, 20TH CENTURY; HUMANS; INTRACELLULAR SPACE; ISOENZYMES; L-LACTATE DEHYDROGENASE; LACTIC ACID; MITOCHONDRIA, MUSCLE; MUSCLE, SKELETAL; PHYSIOLOGY; RESEARCH;

EID: 50349086384     PISSN: 00916331     EISSN: None     Source Type: Journal    
DOI: 10.1097/JES.0b013e31817c0038     Document Type: Review

References (30)

1. Baba, N., and H.M. Sharma. Histochemistry of lactic dehydrogenase in heart and pectoralis muscles of rat. J. Cell. Biol. 51:621-635, 1971.
2. Benninga, H. A History of Lactic Acid Making: A Chapter in the History of Biotechnology. Boston, MA: Kluwer Academic Publishers, 1990, pp. 1-61.
3. Brandt, R.B., J.E. Laux, S.E. Spain2hour, and E.S. Kline. Lactate dehydrogenase in rat mitochondria. Arch. Biochem. Biophys. 259:412-422, 1987.
4. Brooks, G.A., M.A. Brown, C.E. Butz, J.P. Sicurello, and H. Dubouchaud. Cardiac and skeletal muscle mitochondria have a monocarboxylate transporter MCT1. J. Appl. Physiol. 87:1713-1718, 1999.
5. Brooks, G.A., H. Dubouchaud, M. Brown, J.P. Sicurello, and C.E. Butz. Role of mitochondrial lactate dehydrogenase and lactate oxidation in the intracellular lactate shuttle. Proc. Natl. Acad. Sci. U.S.A. 96:1129-1134, 1999.
6. Cahn, R.D., N.O. Kaplan, L. Levine, and E. Zwilling. Nature and development of lactic dehydrogenases. Science. 136:926-969, 1962.
7. Chretien, D., M. Pourrier, T. Bourgeron, M. Séné, A. Rötig, A. Munnich, and P. Rustin. An improved spectrophotometric assay of pyruvate dehydrogenase in lactate dehydrogenase contaminated mitochondrial preparations from human skeletal muscle. Clin. Chim. Acta. 240:129-136, 1995.
8. Deimann, W., R. Freeman, and H.D. Fahimi. Improved contrast in cytochemistry of dehydrogenases by scanning transmission electron microscopy. J. Histochem. Cytochem. 29:678-681, 1981.
9. Gladden, L.B. Lactate metabolism: a new paradigm for the third millennium. J. Physiol. 558(Pt 1):5-30, 2004.
10. Gladden, L.B. A "lactatic" perspective on metabolism. Med. Sci. Sports. Exerc. 40:477-485, 2008.
11. Hashimoto, T., and G.A. Brooks. Mitochondrial lactate oxidation complex and an adaptive role for lactate production. Med. Sci. Sports Exerc. 40:486-494, 2008.
12. Hashimoto, T., R. Hussien, and G.A. Brooks. Colocalization of MCT1, CD147, and LDH in mitochondrial inner membrane of L6 muscle cells: evidence of a mitochondrial lactate oxidation complex. Am. J. Physiol. Endocrinol. Metab. 290:E1237-1244, 2006.
13. Hashimoto, T., S. Masuda, S. Taguchi, and G.A. Brooks. Immunohistochemical analysis of MCT1, MCT2 and MCT4 expression in rat plantaris muscle. J. Physiol. 567(Pt 1):121-129, 2005.
14. Hildyard, J.C.W., C. Ammälä, I.D. Dukes, S.A. Thomson, and A.P. Halestrap. Identification and characterisation of a new class of highly specific and potent inhibitors of the mitochondrial pyruvate carrier. Biochim. Biophys. Acta. 1707:221-230, 2005.
15. James, J.H., F.A. Luchette, F.D. McCarter, and J.E. Fischer. Lactate is an unreliable indicator of tissue hypoxia in injury or sepsis. Lancet. 354:505-508, 1999.
16. Kline, E.S., R.B. Brandt, J.E. Laux, S.E. Spainhour, E.S. Higgins, K.S. Rogers, S.B. Tinsley, and M. G. Waters. Localization of L-lactate dehydrogenase in mitochondria. Arch. Biochem. Biophys. 246:673-680, 1986.
17. Markert, C.L., and F. Møller. Multiple forms of enzymes: tissue, ontogenetic, and species specific patterns. Proc. Natl. Acad. Sci. U. S. A. 45:753-763, 1959.
18. Nakae, Y., and P.J. Stoward. Effects of tissue protectants on the kinetics of lactate dehydrogenase in cells. J. Histochem. Cytochem. 45:1417-1425, 1997.
19. Needham, D.M. Machina Carnis: The Biochemistry of Muscular Contraction in Its Historical Development. Cambridge, UK: Cambridge University Press, 1971, 782.
20. Needham, J. Introduction. In: The Chemistry of Life; Eight Lectures on the History of Biochemistry, J. Needham (Ed.). Cambridge, UK: University Press, 1970, pp. vii-xxx.
21. Newsholme, E.A. Enzymes, energy and endurance. Some provocative thoughts. In: Principles of Exercise Biochemistry, J.R. Poortmans (Ed.). Basel, Switzerland: Karger, 2004, pp. 1-35.
22. Ponsot, E., J. Zoll, B. N'Guessan, F. Ribera, E. Lampert, R. Richard, V. Veksler, R. Ventura-Clapier, and B. Mettauer. Mitochondrial tissue specificity of substrates utilization in rat cardiac and skeletal muscles. J. Cell. Physiol. 203:479-486, 2005.
23. Rasmussen, H.N., G. van Hall, and U.F. Rasmussen. Lactate dehydrogenase is not a mitochondrial enzyme in human and mouse vastus lateralis muscle. J. Physiol. 541(Pt 2):575-580, 2002.
24. Sahlin, K., M. Fernström, M. Svensson, and M. Tonkonogi. No evidence of an intracellular lactate shuttle in rat skeletal muscle. J. Physiol. 541(Pt 2):569-574, 2002.
25. Skilleter, D.N., and E. Kun. The oxidation of L-lactate by liver mitochondria. Arch. Biochem. Biophys. 152:92-104, 1972.
26. Szczesna-Kaczmarek, A. L-lactate oxidation by skeletal muscle mitochondria. Int. J. Biochem. 22:617-620, 1990.
27. Van Hall, G. Lactate as a fuel for mitochondrial respiration. Acta. Physiol. Scand. 168:643-656, 2000.
28. A Biographical Dictionary of Scientists. 3rd ed. T.I. Williams (Ed.). New York, NY: John Wiley and Sons, 1982.
29. Willis, W.T., A. Thompson, J.I. Messer, and J.S. Thresher. Vmax of mitochondrial electron shuttles in rat skeletal muscle and liver (Abstract). Med. Sci. Sports. Exerc. 35:S396, 2003.
30. Yoshida, Y., G.P. Holloway, V. Ljubicic, H. Hatta, L.L. Spriet, D.A. Hood, and A. Bonen. Negligible direct lactate oxidation in subsarcolemmal and intermyofibrillar mitochondria obtained from red and white rat skeletal muscle. J. Physiol. 582(Pt 3):1317-1335, 2007.