Perfusion CT imaging follows clinical severity in left hemispheric strokes

European Neurology

Volumn 60, Issue 5, 2008, Pages 244-252

  Furtado, A D ^a   Smith, W S ^b   Koroshetz, W ^c   Dillon, W P ^a   Furie, K L ^c   Lev, M H ^c   Vittinghoff, E ^a   Schaeffer, S ^a   Biagini, T ^b   Hazarika, O ^b   Wintermark, M ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d Paion ^*

Author keywords

Clinical severity, stroke; Left hemispheric stroke; Noncontrast CT, stroke; Perfusion CT, stroke

Indexed keywords

ADULT; AGED; ARTICLE; CEREBROVASCULAR ACCIDENT; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FOLLOW UP; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HUMAN; ISCHEMIA; MAJOR CLINICAL STUDY; MALE; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; NEUROIMAGING; OUTCOME ASSESSMENT; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; BRAIN; CONTRAST MEDIA; FEMALE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MALE; MIDDLE AGED; STROKE; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 50249187669     PISSN: 00143022     EISSN: None     Source Type: Journal    
DOI: 10.1159/000151700     Document Type: Article

References (45)

1. Brott T, Adams HP Jr, Olinger CP, et al: Measurements of acute cerebral infarction: a clinical examination scale. Stroke 1989;20:864-870.
2. National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group: Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995;333:1581-1587.
3. Rankin J: Cerebral vascular accidents in patients over the age of 60. II. Prognosis. Scott Med J 1957;2:200-215.
4. Bamford JM, Sandercock PA, Warlow CP, Slattery J: Interobserver agreement for the assessment of handicap in stroke patients. Stroke 1989;20:828.
5. Menezes NM, Ay H, Wang Zhu M, et al: The real estate factor: quantifying the impact of infarct location on stroke severity. Stroke 2007;38:194-197.
6. Hillis AE, Wityk RJ, Barker PB, et al: Change in perfusion in acute nondominant hemisphere stroke may be better estimated by tests of hemispatial neglect than by the National Institutes of Health Stroke Scale. Stroke 2003;34:2392-2396.
7. Ringman JM, Saver JL, Woolson RF, et al: Frequency, risk factors, anatomy, and course of unilateral neglect in an acute stroke cohort. Neurology 2004;63:468-474.
8. Fink JN, Selim MH, Kumar S, et al: Is the association of National Institutes of Health Stroke Scale scores and acute magnetic resonance imaging stroke volume equal for patients with right- and left-hemisphere ischemic stroke? Stroke 2002;33:954-958.
9. Ward NS: Neural plasticity and recovery of function. Prog Brain Res 2005;150:527-535.
10. Butefisch CM: Plasticity in the human cerebral cortex: lessons from the normal brain and from stroke. Neuroscientist 2004;10:163-173.
11. Hacke W, Kaste M, Fieschi C, et al, Second European-Australasian Acute Stroke Study Investigators: Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Lancet 1998;352:1245-1251.
12. Wardlaw JM, Zoppo G, Yamaguchi T, Berge E: Thrombolysis for acute ischaemic stroke. Cochrane Database Syst Rev 2003:CD000213.
13. NINDS t-PA Stroke Study Group: Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke. Stroke 1997;28:2109-2118.
14. Steiner T, Bluhmki E, Kaste M, et al: The ECASS 3-hour cohort. Secondary analysis of ECASS data by time stratification. ECASS Study Group. European Cooperative Acute Stroke Study. Cerebrovasc Dis 1998;8:198-203.
15. Albers GW, Clark WM, Madden KP, Hamilton SA: ATLANTIS trial: results for patients treated within 3 hours of stroke onset. Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke. Stroke 2002;33:493-495.
16. Hacke W, Albers G, Al-Rawi Y, et al: The Desmoteplase in Acute Ischemic Stroke Trial (DIAS): a phase II MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase. Stroke 2005;36:66-73.
17. Furlan AJ, Eyding D, Albers GW, et al: Dose Escalation of Desmoteplase for Acute Ischemic Stroke (DEDAS): evidence of safety and efficacy 3 to 9 h after stroke onset. Stroke 2006;37:1227-1231.
18. Croquelois A, Wintermark M, Reichhart M, et al: Aphasia in hyperacute stroke: language follows brain penumbra dynamics. Ann Neurol 2003;54:321-329.
19. Baird AE, Lovblad KO, Dashe JF, et al: Clinical correlations of diffusion and perfusion lesion volumes in acute ischemic stroke. Cerebrovasc Dis 2000;10:441-448.
20. Warach S, Latour LL: Evidence of reperfusion injury, exacerbated by thrombolytic therapy, in human focal brain ischemia using a novel imaging marker of early bloodbrain barrier disruption. Stroke 2004;35:2659-2661.
21. Schellinger PD, Latour LL, Wu CS, et al: The association between neurological deficit in acute ischemic stroke and mean transit time: comparison of four different perfusion MRI algorithms. Neuroradiology 2006;48:69-77.
22. Simak J, Gelderman MP, Yu H, et al: Circulating endothelial microparticles in acute ischemic stroke: a link to severity, lesion volume and outcome. J Thromb Haemost 2006; 4:1296-1302.
23. Schellinger PD, Jansen O, Fiebach JB, et al: Monitoring intravenous recombinant tissue plasminogen activator thrombolysis for acute ischemic stroke with diffusion and perfusion MRI. Stroke 2000;31:1318-1328.
24. Schellinger PD, Chalela JA, Kang DW, et al: Diagnostic and prognostic value of early MR imaging vessel signs in hyperacute stroke patients imaged <3 h and treated with recombinant tissue plasminogen activator. AJNR Am J Neuroradiol 2005;26:618-624.
25. Nighoghossian N, Hermier M, Adeleine P, et al: Baseline magnetic resonance imaging parameters and stroke outcome in patients treated by intravenous tissue plasminogen activator. Stroke 2003;34:458-463.
26. Kaste M: Reborn workhorse, CT, pulls the wagon toward thrombolysis beyond 3 hours. Stroke 2004;35:357-359.
27. Mitsias PD, Ewing JR, Lu M, et al: Multiparametric iterative self-organizing MR imaging data analysis technique for assessment of tissue viability in acute cerebral ischemia. AJNR Am J Neuroradiol 2004;25:1499-1508.
28. Nuutinen J, Liu Y, Laakso MP, et al: Assessing the outcome of stroke: a comparison between MRI and clinical stroke scales. Acta Neurol Scand 2006;113:100-107.
29. Sanak D, Nosal V, Horak D, et al: Impact of diffusion-weighted MRI-measured initial cerebral infarction volume on clinical outcome in acute stroke patients with middle cerebral artery occlusion treated by thrombolysis. Neuroradiology 2006;48:632-639.
30. Ritter MA, Poeplau T, Schaefer A, et al: CT angiography in acute stroke - does it provide additional information on occurrence of infarction and functional outcome after 3 months? Cerebrovasc Dis 2006;22:362-367.
31. Patel SC, Levine SR, Tilley BC, et al: Lack of clinical significance of early ischemic changes on computed tomography in acute stroke. JAMA 2001;286:2830-2838.
32. Linfante I, Llinas RH, Schlaug G, et al: Diffusion-weighted imaging and National Institutes of Health Stroke Scale in the acute phase of posterior-circulation stroke. Arch Neurol 2001;58:621-628.
33. Ernst R, Pancioli A, Tomsick T, et al: Combined intravenous and intra-arterial recombinant tissue plasminogen activator in acute ischemic stroke. Stroke 2000;31:2552-2557.
34. Tong DC, Yenari MA, Albers GW, et al: Correlation of perfusion- and diffusion-weighted MRI with NIHSS score in acute (<6.5 h) ischemic stroke. Neurology 1998;50:864-870.
35. Tei H, Uchiyama S, Usui T: Clinical-diffusion mismatch defined by NIHSS and ASPECTS in non-lacunar anterior circulation infarction. J Neurol 2007;254:340-346.
36. Wintermark M, Maeder P, Thiran JP, et al: Quantitative assessment of regional cerebral blood flows by perfusion CT studies at low injection rates: a critical review of the underlying theoretical models. Eur Radiol 2001;11:1220-1230.
37. Axel L: Tissue mean transit time from dynamic computed tomography by a simple deconvolution technique. Invest Radiol 1983;18:94-99.
38. Zilkha E, Ladurner G, Iliff LD, et al: Computer subtraction in regional cerebral blood volume measurements using the EMI Scanner. Br J Radiol 1976;49:330-334.
39. Wintermark M, Flanders AE, Velthuis B, et al: Perfusion CT assessment of infarct core and penumbra: receiver operating characteristic curve analysis in 130 patients suspected of acute hemispheric stroke. Stroke 2006;37:979-985.
40. Pexman JH, Barber PA, Hill MD, et al: Use of the Alberta Stroke Program Early CT Score (ASPECTS) for assessing CT scans in patients with acute stroke. AJNR Am J Neuroradiol 2001;22:1534-1542.
41. Wintermark M, Reichhart M, Thiran JP, et al: Prognostic accuracy of cerebral blood flow measurement by perfusion computed tomography, at the time of emergency room admission, in acute stroke patients. Ann Neurol 2002;51:417-432.
42. Murphy BD, Fox AJ, Lee DH, et al: Identification of penumbra and infarct in acute ischemic stroke using computed tomography perfusion-derived blood flow and blood volume measurements. Stroke 2006;37:1771-1777.
43. Schaefer PW, Roccatagliata L, Ledezma C, et al: First-pass quantitative CT perfusion identifies thresholds for salvageable penumbra in acute stroke patients treated with intra-arterial therapy. AJNR Am J Neuroradiol 2006;27:20-25.
44. Wintermark M, Fischbein NJ, Smith WS, et al: Accuracy of dynamic perfusion CT with deconvolution in detecting acute hemispheric stroke. AJNR Am J Neuroradiol 2005;26:104-112.
45. Lovblad KO, Baird AE, Schlaug G, et al: Ischemic lesion volumes in acute stroke by diffusion-weighted magnetic resonance imaging correlate with clinical outcome. Ann Neurol 1997;42:164-170.