The - 384A > C polymorphism of endothelial lipase gene promoter region in Chinese healthy normolipidemic and endogenous hypertriglyceridemic subjects

Chinese Journal of Medical Genetics

Volumn 25, Issue 4, 2008, Pages 443-446

  Huang, Yi ^a   Bai, Huai ^a   Fan, Ping ^a   Liu, Rui ^b   Liu, Yu ^a   Liu, Bing Wen ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Endogenous hypertriglyceridemia; Endothelial lipase; Gene polymorphism

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN A2; APOLIPOPROTEIN B100; APOLIPOPROTEIN C2; APOLIPOPROTEIN C3; APOLIPOPROTEIN E; LIPID; TRIACYLGLYCEROL;

ALLELE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HYPERTRIGLYCERIDEMIA; IMMUNODIFFUSION; LIPID BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEX DIFFERENCE; STATISTICAL SIGNIFICANCE;

ADULT; AGED; AGED, 80 AND OVER; ALLELES; APOLIPOPROTEINS C; ASIAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; HUMANS; HYPERTRIGLYCERIDEMIA; LIPASE; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POPULATION GROUPS; PROMOTER REGIONS, GENETIC; TRIGLYCERIDES; YOUNG ADULT;

EID: 50249182361     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Jaye M, Lynchi KJ, Krawiec J, et al. A novel endothelial-derived lipase that modulates HDL metabolism. Nat Genet, 1999, 21:424-428.
2. Hirata K, Dichek HL, Cioffi JA, et al. Cloning of a unique lipase from endothelial cells extends the lipase gene family. J Biol Chem, 1999, 274:14170-14175.
3. Ishida T, Choi S, Kundu RK, et al. Endothelial lipase is a major determinant of HDL level. J Clin Invest, 2003, 111:347-355.
4. Jin W, Millar JS, Broedl U, et al. Inhibition of endothelial liapse causes increased HDL cholesterol levels in vivo. J Clin Invest, 2003, 111:357-362.
5. Broedl UC, Mangeais C, Millar JS, et al. Endothelial lipase promotes the catabolism of apoB-containing lipoproteins. Circ Res, 2004, 94:1554-1561.
6. Ishida T, Zheng Z, Dichek HL, et al. Molecular cloning of nonsecreted endothelial cell-derived lipase isoforms. Genomics, 2004, 83:24-33.
7. Yamakawa-Kobayashi K, Yanai H, Endo K, et al. Relationship between serum HDL-C levels and common genetic variants of the endothelial lipase gene in Japanese school-aged children. Hum Genet, 2003, 113:311-315.
8. Hutter CM, Austin MA, Farin FM, et al. Association of endothelial lipase (LIPG) haplotypes with high-density lipoprotein cholesterol subfractions and apolipoprotein AI plasma levels in Japanese Americans. Atherosclerosis, 2006, 185:78-86.
9. Erlich HA, ed. Principles and applications for DNA amplification. In: Higuchi R. PCR technology. New York: Stockton Press, 1989. 36.
10. Liu BW. Immunoassay for human apolipoprotein and its clinical application. In: Wang KQ. Ed. Lipoprotein and arteriosclerosis. 1st ed. Beijing: People Health Publishing House, 1995:359-360.
11. Friedewakd WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem, 1972, 18:499-502.
12. Zhang QP, Liu BW, Liu Y, et al. Common genetic variants of lipoprotein lipase and hepatic lipase in Chinese endogenous hypertriglyceridemics. Chin J Med Genet, 1997, 14:289-293.
13. Zhang R, Liu BW, Bai H. A study of lipoprotein lipase gene Hind III polymorphism associated with Chinese endogenous hypertriglyceridemics. Chin J Arterioscler, 2001, 9:49-52.