메뉴 건너뛰기




Volumn 40, Issue 8, 2008, Pages 539-543

Cetilistat (ATL-962), a novel pancreatic lipase inhibitor, ameliorates body weight gain and improves lipid profiles in rats

Author keywords

High fat diet; Nonesterified fatty acid; Total cholesterol; Triglyceride; Visceral fat; White adipose tissue

Indexed keywords

CETILISTAT; CHOLESTEROL; LEPTIN; LIPID; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE;

EID: 50249171836     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1076699     Document Type: Article
Times cited : (45)

References (14)
  • 1
    • 0033830448 scopus 로고    scopus 로고
    • Regulation of metabolism and body fat mass by leptin
    • Baile CA, Della-Fera MA, Martin RJ. Regulation of metabolism and body fat mass by leptin. Annu Rev Nutr 2000; 20: 105-127
    • (2000) Annu Rev Nutr , vol.20 , pp. 105-127
    • Baile, C.A.1    Della-Fera, M.A.2    Martin, R.J.3
  • 2
    • 33845886915 scopus 로고    scopus 로고
    • Abdominal obesity and metabolic syndrome
    • Despres JP, Lemieux I. Abdominal obesity and metabolic syndrome. Nature 2006; 444: 881-887
    • (2006) Nature , vol.444 , pp. 881-887
    • Despres, J.P.1    Lemieux, I.2
  • 3
    • 24644438086 scopus 로고    scopus 로고
    • International Diabetes Federation
    • Diabetes Atlas Committee, Executive Summary 2nd edition
    • Diabetes Atlas Committee. International Diabetes Federation. In: Diabetes Atlas Executive Summary 2nd edition 2003
    • (2003) Diabetes Atlas
  • 4
    • 0037423243 scopus 로고    scopus 로고
    • Obesity: What is to be done?
    • Kelner K, Helmuth L. Obesity: What is to be done? Science 2003; 299: 846-860
    • (2003) Science , vol.299 , pp. 846-860
    • Kelner, K.1    Helmuth, L.2
  • 5
    • 33847261129 scopus 로고    scopus 로고
    • Cetilistat (ATL-962), a novel lipase inhibitor: A 12-week randomized, placebo-controlled study of weight reduction in obese patients
    • Kopelman P, Bryson A, Hickiing R, Rissanen A, Rossner S, Toubro S, Valensi P. Cetilistat (ATL-962), a novel lipase inhibitor: a 12-week randomized, placebo-controlled study of weight reduction in obese patients. Int J Obes 2007; 31: 494-499
    • (2007) Int J Obes , vol.31 , pp. 494-499
    • Kopelman, P.1    Bryson, A.2    Hickiing, R.3    Rissanen, A.4    Rossner, S.5    Toubro, S.6    Valensi, P.7
  • 6
    • 0037423327 scopus 로고    scopus 로고
    • Obesity drug pipeline not so fat
    • Cura T. Obesity drug pipeline not so fat. Science 2003; 299: 849-852
    • (2003) Science , vol.299 , pp. 849-852
    • Cura, T.1
  • 8
    • 33845642664 scopus 로고    scopus 로고
    • The role of leptin and ghrelin in the regulation of food intake and body weight in humans: A review
    • Klok MD, Jakobsdottir S, Drent ML. The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review. Obes Rev 2007; 8: 21-34
    • (2007) Obes Rev , vol.8 , pp. 21-34
    • Klok, M.D.1    Jakobsdottir, S.2    Drent, M.L.3
  • 9
    • 0025911832 scopus 로고
    • The lipase inhibitor tetrahydrolipstatin binds covalently to the putative active site serine of pancreatic lipase
    • Harvary P, Sidler W, Meister W, Vetter W, Wolfer H. The lipase inhibitor tetrahydrolipstatin binds covalently to the putative active site serine of pancreatic lipase.J Biol Chem 1991; 266: 2021-2027
    • (1991) J Biol Chem , vol.266 , pp. 2021-2027
    • Harvary, P.1    Sidler, W.2    Meister, W.3    Vetter, W.4    Wolfer, H.5
  • 10
    • 0023544338 scopus 로고
    • Studies on the antiobesity activity of tetrahydrolipstatin, a potent and selective inhibitor of pancreatic lipase
    • Hogan S, Fleury A, Hadvery P, Lengsfeld H, Meier MK, Triscari J, Sullivan AC. Studies on the antiobesity activity of tetrahydrolipstatin, a potent and selective inhibitor of pancreatic lipase. Int J Obes 1987; 11 (Suppl. 3): 35-42
    • (1987) Int J Obes , vol.11 , Issue.SUPPL. 3 , pp. 35-42
    • Hogan, S.1    Fleury, A.2    Hadvery, P.3    Lengsfeld, H.4    Meier, M.K.5    Triscari, J.6    Sullivan, A.C.7
  • 11
    • 0032543870 scopus 로고    scopus 로고
    • For the European Multicentre Orlistat Study Group: Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients
    • Sjostrom L, Rissanen A, Andersen T, Boldrin M, Golay A, Kopperschaar HPF, Krempf M. For the European Multicentre Orlistat Study Group: Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. Lancet 1998; 352: 167-172
    • (1998) Lancet , vol.352 , pp. 167-172
    • Sjostrom, L.1    Rissanen, A.2    Andersen, T.3    Boldrin, M.4    Golay, A.5    Kopperschaar, H.P.F.6    Krempf, M.7
  • 12
    • 0029597837 scopus 로고
    • Association of postprandial triglyceride and retinyl palmitate responses with asymptomatic carotid artery atherosclerosis in middle-aged men and women: The Atherosclerosis Risk in Communities (ARIC) Study
    • Sharrett AR, Chambless IE, Heiss G, Paton CC, Patsch W. Association of postprandial triglyceride and retinyl palmitate responses with asymptomatic carotid artery atherosclerosis in middle-aged men and women: The Atherosclerosis Risk in Communities (ARIC) Study. Arterioscler Thromb Vascu Biol 1995; 15: 2122-2129
    • (1995) Arterioscler Thromb Vascu Biol , vol.15 , pp. 2122-2129
    • Sharrett, A.R.1    Chambless, I.E.2    Heiss, G.3    Paton, C.C.4    Patsch, W.5
  • 13
    • 33645711050 scopus 로고    scopus 로고
    • Cancelas J, Prieto Villanueva-Penacarrillo ML. ValVerde I, Malaisse WJ. Effects of an olive-oil enriched diet on glucagon-like peptide 1 release and intestinal content, plasma insulin concentration, glucose tolerance and pancreatic insulin content in an animal model of type 2 diabetes. Horm Metab Res 2006; 38: 98-105
    • Cancelas J, Prieto PG, Villanueva-Penacarrillo ML. ValVerde I, Malaisse WJ. Effects of an olive-oil enriched diet on glucagon-like peptide 1 release and intestinal content, plasma insulin concentration, glucose tolerance and pancreatic insulin content in an animal model of type 2 diabetes. Horm Metab Res 2006; 38: 98-105
  • 14
    • 34248223285 scopus 로고    scopus 로고
    • Biology of incretins: GLP-1 and GIP
    • Baggio LL, Drucker D. Biology of incretins: GLP-1 and GIP. Gastroenterology 2007; 132: 2131-2157
    • (2007) Gastroenterology , vol.132 , pp. 2131-2157
    • Baggio, L.L.1    Drucker, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.