Neuregulin attenuated cerebral ischemia-Creperfusion injury via inhibiting apoptosis and upregulating aquaporin-4

Neuroscience Letters

Volumn 443, Issue 3, 2008, Pages 155-159

  Li, Qin ^a   Li, Zhen ^a   Mei, Yuanwu ^b   Guo, Yunliang ^a  

^a QINGDAO UNIVERSITY MEDICAL COLLEGE   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Apoptosis; AQP 4; Cerebral ischemia reperfusion injury; Double fluorescence labeling; Neuregulin; RT PCR; Treatment time window

Indexed keywords

AQUAPORIN 4; MESSENGER RNA; NEU DIFFERENTIATION FACTOR; X LINKED INHIBITOR OF APOPTOSIS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN DAMAGE; BRAIN FUNCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; DISEASE DURATION; DRUG MECHANISM; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MITOCHONDRION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCORING SYSTEM; TREATMENT OUTCOME; UPREGULATION;

ANIMALS; APOPTOSIS; AQUAPORIN 4; BEHAVIOR, ANIMAL; BRAIN; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; MALE; NEUREGULIN-1; RATS; RATS, WISTAR; REPERFUSION INJURY; RNA, MESSENGER; TIME FACTORS; UP-REGULATION; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 50249157443     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2008.07.064     Document Type: Article

References (23)

1. Badaut J., Lasbennes F., Magistretti P.J., and Regli L. Aquaporins in brain: distribution, physiology, and pathophysiology[J]. J Cereb Blood Flow Metab 22 3 (2002) 367-378
2. Bourekas E.C., Slivka A.P., Shah R., Sunshine J., and Suarez J.I. Intraarterial thrombolyic therapy with 3 hours of the onset of stroke[J]. Neurosurg 54 1 (2004) 39-44
3. Chen C.H., Xue R., Zhang J., Li X., Mori S., and Bhardwaj A. Effect of osmotherapy with hypertonic saline on regional cerebral edema following experimental stroke: a study utilizing magnetic resonance imaging[J]. Neurocrit Care 7 1 (2007) 92-100
4. Da T., and Verkman A.S. Aquaporin-4 gene disruption in mice protects against impaired retinal function and cell death after ischemia. Invest Ophthalmol Vis Sci 45 12 (2004) 4477-4483
5. Dimayuga F.O., Ding Q., Keller J.N., Marchionni M.A., Seroogy K.B., and Bruce-Keller A.J. The neuregulin GGF2 attenuates free radical release from activated microglial cells[J]. J Neuroimmunol 136 1-2 (2003) 67-74
6. Frydenlund D.S., Bhardwaj A., Otsuka T., Mylonakou M.N., Yasumura T., Davidson K.G., Zeynalov E., Skare O., Laake P., Haug F.M., Rash J.E., Agre P., Ottersen O.P., and Amiry-Moghaddam M. Temporary loss of perivascular aquaporin-4 in neocortex after transient middle cerebral artery occlusion in mice[J]. Proc Natl Acad Sci USA 103 36 (2006) 13532-13536
7. Longa E.Z., Weinstein P.R., Carlson S., and Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats[J]. Stroke 20 1 (1989) 84-91
8. Liu D., Smith C.L., Barone F.C., Ellison J.A., Lysko P.G., Li K., and Simpson I.A. Astrocytic demise precedes delayed neuronal death in focal ischemic rat brain[J]. Brain Res Mol Brain Res 68 1 (1999) 29-41
9. Li Y., Xu Z., Ford G.D., Croslan D.R., Cairobe T., Li Z., and Ford B.D. Neuroprotection by neuregulin-1 in a rat model of permanent focal cerebral ischemia[J]. Brain Res 1184 (2007) 277-283
10. Papadopoulos M.C., Krishna S., and Verkman A.S. Aquaporin water channels and brain edema. Mt Sinai J Med 69 2 (2002) 242-248
11. Papadopoulos M.C., Manley G.T., Krishna S., and Verkman A.S. Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema [J]. FASEB J 18 11 (2004) 1291-1293
12. Saito A., Hayashi T., Okuno S., Ferrand-Drake M., and Chan P.H. Interaction between XIAP and Smac/DIABLO in the mouse brain after transient focal cerebral ischemia[J]. J Cereb Blood Flow Metab 23 9 (2003) 1010-1019
13. Saito A., Hayashi T., Okuno S., Nishi T., and Chan P.H. Oxidative stress is associated with XIAP and Smac/DIABLO signaling pathways in mouse brains after transient focal cerebral ischemia[J]. Stroke 35 6 (2004) 1443-1448
14. Srinivasula S.M., Gupta S., Datta P., Zhang Z., Hegde R., Cheong N., Fernandes-Alnemri T., and Alnemri E.S. Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2[J]. J Biol Chem 278 34 (2003) 31469-31472
15. Suzuki R., Okuda M., Asai J., Nagashima G., Itokawa H., Matsunaga A., Fujimoto T., and Suzuki T. Astrocytes co-express aquaporin-1, -4, and vascular endothelial growth factor in brain edema tissue associated with brain contusion[J]. Acta Neurochir Suppl 96 (2006) 398-401
16. Taniguchi M., Yamashita T., Kumura E., Tamatani M., Kobayashi A., Yokawa T., Maruno M., Kato A., Ohnishi T., Kohmura E., Tohyama M., and Yoshimine T. Induction of aquaporin-4 water channel mRNA after focal cerebral ischemia in rat[J]. Brain Res Mol Brain Res 78 1-2 (2000) 131-137
17. Tokita Y., Keino H., Matsui F., Aono S., Ishiguro H., Higashiyama S., and Oohira A. Regulation of neuregulin expression in the injured rat brain and cultured astrocytes[J]. J Neurosci 21 4 (2001) 1257-1264
18. Trapp T., Korhonen L., Besselmann M., Martinez R., Mercer E.A., and Lindholm D. Transgenic mice overexpressing XIAP in neurons show better outcome after transient cerebral ischemia[J]. Mol Cell Neurosci 23 2 (2003) 302-313
19. Venero J.L., Vizuete M.L., Machado A., and Cano J. Aquaporins in the central nervous system[J]. Prog Neurobiol 63 3 (2001) 321-336
20. Wang X., Zhu C., Wang X., Hagberg H., Korhonen L., Sandberg M., Lindholm D., and Blomgren K. X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia[J]. Neurobiol Dis 16 1 (2004) 179-189
21. Xu Z., and Ford B.D. Upregulation of erbB receptors in rat brain after middle cerebral arterial occlusion. Neuroscience Letters 375 3 (2005) 181-186
22. Xu Z., Ford G.D., Croslan D.R., Jiang J., Gates A., Allen R., and Ford B.D. Neuroprotection by neuregulin-1 following focal stroke is associated with the attenuation of ischemia-induced pro-inflammatory and stress gene expression[J]. Neurobiol Dis 19 3 (2005) 461-470
23. Zhu C., Wang X., Xu F., Bahr B.A., Shibata M., Uchiyama Y., Hagberg H., and Blomgren K. The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia[J]. Cell Death Differ 12 2 (2005) 162-176