Release characteristics and in vitro-in vivo correlation of pulsatile pattern for a pulsatile drug delivery system activated by membrane rupture via osmotic pressure and swelling

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 70, Issue 1, 2008, Pages 289-301

  Lin, Hong Liang ^a   Lin, Shyr Yi ^a,b   Lin, Ying Ku ^a   Ho, Hsiu O ^a   Lo, Yo Wen ^a   Sheu, Ming Thau ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Ethylcellulose; Hydroxypropylmethylcellulose (HPMC); Lag time; Membrane Rupture; Pulsatile Release

Indexed keywords

AEROSIL; DOXAZOSIN MESYLATE; DOXOBEN XL; ETHYL CELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; MAGNESIUM STEARATE; PLASTICIZER; PRAZOSIN; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CONTROLLED STUDY; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG SOLUBILITY; GELATION; HUMAN; HUMAN EXPERIMENT; HYDROPHILICITY; IN VITRO STUDY; IN VIVO STUDY; IONIC STRENGTH; MEMBRANE RUPTURE; NORMAL HUMAN; OSMOTIC PRESSURE; PH; PULSATILE DRUG RELEASE; THICKNESS; VISCOSITY;

ADMINISTRATION, ORAL; ADULT; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; CROSS-OVER STUDIES; DELAYED-ACTION PREPARATIONS; DOXAZOSIN; DRUG CARRIERS; HUMANS; HYDROGEN-ION CONCENTRATION; MEMBRANES, ARTIFICIAL; METHYLCELLULOSE; MODELS, BIOLOGICAL; OSMOTIC PRESSURE; PERMEABILITY; PILOT PROJECTS; PULSE THERAPY, DRUG; SODIUM CHLORIDE; SOLUBILITY; TABLETS; VISCOSITY; WATER;

EID: 50149114921     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2008.03.021     Document Type: Article

References (29)

1. Reinberg A.E. Concepts in chronopharmacology. Annu. Rev. Pharmacol. Toxicol. 32 (1992) 51-66
2. Lemmer B. The clinical relevance of chronopharmacology. Pharmacol. Res. 33 (1996) 107-115
3. Smlensky M.H., and D'alonzo G.E. Medical chronobiology: concepts and applications. Am. Rev. Respir. Dis. 147 (1993) s2-s19
4. D'Emanuele A. Responsive polymeric drug delivery. Clin. Pharmacokinet. 31 (1996) 241-245
5. Yoshida R., Sakai K., Okano T., and Sakurai Y. Pulsatile drug delivery systems using hydrogels. Adv. Drug Deliv. Rev. 11 (1993) 85-108
6. Lin S.Y., Lin Y.Y., and Chen K.S. Permeation behavior of salbutamol sulfate through hydrophilic and hydrophobic membranes embedded by thermo-responsive cholesteryl oleyl carbonate. Pharm. Res. 13 (1996) 914-919
7. Lin S.Y., Chen K.S., and Lin Y.Y. Artificial thermo-responsive membrane able to control on-off switching drug release through nude mice skin without interference from skin penetrating enhancers. J. Bioact. Comp. Polym. 15 (2000) 170-178
8. Krögel I., and Bodmeier R. Floating or pulsatile drug delivery systems based on coated effervescent cores. Int. J. Pharm. 187 (1999) 175-184
9. W. Phuapradit, A. Railkar, N.H. Shah, Pharmaceutical composition, EP Patent 0,673,645, September 27, 1995.
10. Gazzaniga A., Iamartino P., Maffione G., and Sangalli M.E. Oral delayed-release system for colonic specific delivery. Int. J. Pharm. 108 (1994) 77-83
11. Sangalli M.E., Maroni A., Zema L., Busetti C., Giordano F., and Gazzaniga A. In vitro and in vivo evaluation of an oral system for time and/or site-specific drug delivery. J. Control. Release 79 (2001) 103-110
12. Hejazi R., and Amiji M. Chitosan-based gastrointestinal delivery systems. J. Control. Release 89 (2003) 151-165
13. M.E. McNeil, A. Rashid, H.N.E. Stevens, Drug dispensing device, US Patent, 5,342,624, 1994.
14. Ross A.C., Macrae R.J., Walther M., and Stevens H.N.E. Chronopharmaceutical drug delivery from a pulsatile capsule device based on programmable erosion. J. Pharm. Pharmacol. 52 (2000) 903-909
15. Gohel M.C., and Sumitra G M. Modulation of active pharmaceutical material release from a novel 'tablet in capsule system' containing an effervescent blend. J. Control. Release 79 (2002) 157-164
16. Cao Q.R., Choi H.G., Kim D.C., and Lee B.J. Release behavior and photo-image of nifedipine tablet coated with high viscosity hydroxypropylmethylcellulose: effect of coating conditions. Int. J. Pharm. 274 (2004) 107-117
17. Wan L.S.C., Heng P.W.S., and Wong L.F. Relationship between swelling and drug release in a hydrophilic matrix. Drug Dev. Ind. Pharm. 19 (1993) 1201-1210
18. Tahara K., Yamamoto K., and Nishihara T. Overall mechanism behind matrix sustained release (SR) tablets prepared with hydroxypropylmethylcellulose 2910. J. Control. Release 35 (1995) 59-66
19. Matsuo M., Nakamura C., Arimori K., and Nakano M. Evaluation of hydroxyethylcellulose as a hydrophilic swellable material for delayed-release tablets. Chem. Pharm. Bull. 43 (1995) 311-314
20. Takeuchi H., Yasuji T., Hino T., Yamamoto H., and Kawashima Y. Spray-dried composite particles of lactose and sodium alginate for direct tabletting and controlled releasing. Int. J. Pharm. 174 (1998) 91-100
21. Takeuchi H., Yasuji T., Yamamoto H., and Kawashima Y. Spray dried lactose composite particles containing an ion complex of alginate-chitosan for designing a dry-coated tablet having a time-controlled releasing function. Pharm. Res. 17 (2000) 94-99
22. R.W. Baker, Controlled release delivery system by an osmotic bursting mechanism, U.S. Patent 3,952,741, 1976.
23. Razaghi A.M., and Schwartz J.B. Release of cyclobenzaprine hydrochloride from osmotically rupturable tablets. Drug Dev. Ind. Pharm. 28 6 (2002) 695-701
24. Zhang Y., Zhang Z., and Wu F. A novel pulsed-release system based on swelling and osmotic pumping mechanism. J. Control. Release 89 (2003) 47-55
25. Bussemer T., Dashevesky A., and Bodmeier R. A pulsatile drug delivery system based on rupturable coated hard gelatin capsules. J. Control. Release 93 (2003) 331-339
26. Lin S.Y., Lin K.H., and Li M.J. Influence of excipients, drugs, and osmotic agent in the inner core on the time-controlled disintegration of compression-coated ethylcellulose tablets. J. Pharm. Sci. 91 (2002) 2040-2046
27. Lin S.Y., Li M.J., and Lin K.H. Hydrophilic excipients modulate the time lag of time-controlled disintegrating press-coated tablets. AAPS Pharm. Sci. Tech. 5 4 (2004) (article 54)
28. Kao C.C., Chen S.C., and Sheu M.T. Lag time method to delay drug release to various sites in the gastrointestinal tract. J. Control. Release 93 (1997) 263-270
29. Morita R., Honda R., and Takahashi Y. Development of oral controlled release preparations a PVA swelling controlled release system (SCRS) Ι. Design of SCRS and its release controlling factor. J. Control. Release 63 (2000) 297-304