Detection of endogenous DNA adducts, O6-carboxymethyl- 2′-deoxyguanosine and 3-ethanesulfonic acid-2′- deoxycytidine, in the rat stomach after duodenal reflux

Cancer Science

Volumn 99, Issue 9, 2008, Pages 1741-1746

  Terasaki, Masaru ^a   Totsuka, Yukari ^a   Nishimura, Koichi ^a   Mukaisho, Ken Ichi ^b   Chen, Kuan Hao ^b   Hattori, Takanori ^b   Takamura Enya, Takeji ^c   Sugimura, Takashi ^a   Wakabayashi, Keiji ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^c KANAGAWA INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 ETHANESULFONIC ACID 2' DEOXYCYTIDINE; BILE ACID CONJUGATE; DEOXYCYTIDINE; DEOXYGUANOSINE; GLYCOCHOLIC ACID; N NITROSOGLYCOCHOLIC ACID; N NITROSOTAUROCHOLIC ACID; NITROSO DERIVATIVE; O6 CARBOXYMETHYL 2' DEOXYGUANOSINE; TAUROCHOLIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CHEMICAL STRUCTURE; CONTROLLED STUDY; DNA ADDUCT; DUODENOGASTRIC REFLUX; GASTRIC CORPUS; JEJUNUM; NITROSATION; NONHUMAN; PRIORITY JOURNAL; RAT; SHAM PROCEDURE; STOMACH;

ANIMALS; BILE ACIDS AND SALTS; DEOXYCYTIDINE; DEOXYGUANOSINE; DNA ADDUCTS; DUODENOGASTRIC REFLUX; MALE; RATS; RATS, WISTAR; SENSITIVITY AND SPECIFICITY; STOMACH; SULFONIC ACIDS;

EID: 50149100897     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2008.00871.x     Document Type: Article

References (34)

1. Caygill CP, Hill MJ, Kirkham JS, Northfield TC. Mortality from gastric cancer following gastric surgery for peptic ulcer. Lancet 1986; i: 929-31.
2. Viste A, Bjornestad E, Opheim P et al. Risk of carcinoma following gastric operations for benign disease: A historical cohort study of 3470 patients. Lancet 1986; ii: 502-4.
3. Lundegardh G, Adami HO, Helmick C, Zack M, Meirik O. Stomach cancer after partial gastrectomy for benign ulcer disease. N Engl J Med 1988; 319: 195-200.
4. Toftgaard C. Gastric cancer after peptic ulcer surgery. A historic prospective cohort investigation. Ann Surg 1989; 210: 159-64.
5. Mirvish SS. Role of N-nitroso compounds (NOC) and N-nitrosation in etiology of gastric, esophageal, nasopharyngeal and bladder cancer and contribution to cancer of known exposures to NOC. Cancer Lett 1995; 93: 17-48.
6. Dayal B, Ertel NH. Studies on N-nitroso bile acid amides in relation to their possible role in gastrointestinal cancer. Lipids 1997; 32: 1331-40.
7. Ohshima H, Bartsch H. Chronic infections and inflammatory processes as cancer risk factors: Possible role of nitric oxide in carcinogenesis. Mutat Res 1994; 305: 253-64.
8. Ohshima H, Tsuda M, Adachi H, Ogura T, Sugimura T, Esumi H. 1-arginine-dependent formation of N-nitrosamines by the cytosol of macrophages activated with lipopolysaccharide and interferon-γ. Carcinogenesis 1991; 12: 1217-20.
9. Phillips RW, Wong RK. Barrett's esophagus. Natural history, incidence, etiology, and complications. Gastroenterol Clin North Am 1991; 20: 791-816.
10. Attwood SE, Smyrk TC, DeMeester TR, Mirvish SS, Stein HJ, Hinder RA. Duodenoesophageal reflux and the development of esophageal adenocarcinoma in rats. Surgery 1992; 111: 503-10.
11. Stamp DH. Three hypotheses linking bile to carcinogenesis in the gastrointestinal tract: Certain bile salts have properties that may be used to complement chemotherapy. Med Hypotheses 2002; 59: 398-405.
12. Stamp DH. Bile acids aided by acid suppression therapy may be associated with the development of esophageal cancers in westernized societies. Med Hypotheses 2006; 66: 154-7.
13. Gillen P, Keeling P, Byrne PJ, Healy M, O'Moore RR, Hennessy TP. Implication of duodenogastric reflux in the pathogenesis of Barrett's oesophagus. Br J Surg 1988; 75: 540-3.
14. Miwa K, Hasegawa H, Fujimura T et al. Duodenal reflux through the pylorus induces gastric adenocarcinoma in the rat. Carcinogenesis 1992; 13: 2313-16.
15. Miwa K, Kinami S, Miyazaki I, Hattori T. Positive association between dietary fat intake and risk of gastric stump carcinoma in rats. Carcinogenesis 1996; 17: 1885-9.
16. Kumagai H, Mukaisho K, Sugihara H, Miwa K, Yamamoto G, Hattori T. Thioproline inhibits development of esophageal adenocarcinoma induced by gastroduodenal reflux in rats. Carcinogenesis 2004; 25: 723-7.
17. Suo M, Mukaisho K, Shimomura A, Sugihara H, Hattori T. Thioproline prevents carcinogenesis in the remnant stomach induced by duodenal reflux. Cancer Lett 2006; 237: 256-62.
18. Shuker DEG, Tannenbaum SR, Wishnok JS. N-nitroso bile acid conjugates. 1. Synthesis, chemical reactivity, and mutagenic activity. J Org Chem 1981; 46: 2092-6.
19. Puju S, Shuker DEG, Bishop WW, Falchuk KR, Tannenbaum SR, Thilly WG. Mutagenicity of N-nitroso bile acid conjugates in Salmonella typhimurium and diploid human lymphoblasts. Cancer Res 1982; 42: 2601-4.
20. Busby WF, Shuker DEG, Charley G, Newberne PM, Tannenbaum SR, Wogan GN. Carcinogenicity in rats of the nitrosated bile acid conjugates: N-nitrosoglycocholic acid and N-nitrosotaurocholic acid. Cancer Res 1985; 45: 1367-71.
21. 6-methylguanine in DNA. Cancer Res 1997; 57: 366-9.
22. Totsuka Y, Nishigaki R, Enomoto S et al. Structures and biological properties of DNA adducts derived from N-nitroso bile acid conjugates. Chem Res Toxicol 2005; 18: 1553-62.
23. 6- (carboxymethyl)-2′-deoxyguanosine: A DNA adduct formed by nitrosated glycine derivatives. Chem Res Toxicol 1997; 10: 652-9.
24. 4-ethylthymidine in human biomonitoring studies. Chem Res Toxicol 2002; 15: 433-7.
25. Nagaoka H, Wakabayashi K, Kim SB et al. Adduct formation at C-8 of guanine on in vitro reaction of the ultimate form of 2-amino-1-methyl-6-phenylimidazo[4,5-#1b] pyridine with 2′-deoxyguanosine and its phosphate esters. Jpn J Cancer Res 1992; 83: 1025-9.
26. 32P-postlabeling analysis of DNA adducts persisting for up to 42 weeks in the skin, epidermis and dermis of mice treated topically with 7,12-dimethylbenz[a] anthracene. Carcinogenesis 1985; 6: 1117-26.
27. 32 P-post-labeling analysis of aromatic carcinogen: DNA adducts. Cancer Res 1985; 45: 5656-62.
28. 32 P-postlabeling test for structurally diverse DNA adducts. Carcinogenesis 1986; 7: 1543-51.
29. 6- carboxymethyl-2′-deoxyguanosine in DNA following reaction of nitric oxide with glycine and in human blood DNA using a quantitative immunoslot blot assay. Chem Res Toxicol 2004; 17: 294-300.
30. 6-carboxymethyl guanine: implications for colorectal cancer risk. Cancer Res 2006; 66: 1859-65.
31. 6-methyl-2′- deoxyguanosine DNA adducts: Relevance for gastrointestinal cancer. Carcinogenesis 2007; 28: 356-62.
32. Min C, Hesheng L, Jihong C, Qiaoyun T, Xianzhen L, Chireyeth S. Effects and mechanism of changes of local neurotransmitters in rats'pylorus and bile reflux to the stomach with stress ulcer. Dig Dis Sci 2005; 50: 1898-903.
33. 6 -methyl-2′-deoxyguanosine in DNA exposed to nitrosated glycine derivatives using a combined immunoaffinity/HPLC method. Chem Res Toxicol 1999; 12: 106-11.
34. Armstrong D, Rytina ER, Murphy GM, Dowling RH. Gastric mucosal toxicity of duodenal juice constituents in the rat. Acute studies using ex vivo rat gastric chamber model. Dig Dis Sci 1994; 39: 327-39.