Subcutaneous transplantation of autologous oral mucosal epithelial cell sheets fabricated on temperature-responsive culture dishes

Journal of Biomedical Materials Research - Part A

Volumn 86, Issue 4, 2008, Pages 1088-1096

  Obokata, Haruko ^a,b   Yamato, Masayuki ^b   Yang, Joseph ^b   Nishida, Kohji ^c   Tsuneda, Satoshi ^a   Okano, Teruo ^b  

^a WASEDA UNIVERSITY   (Japan)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cell sheet; Phenotypic modulation; Progenitor cell; Tissue engineering autologous cell

Indexed keywords

ANTIBODIES; CELL CULTURE; CYTOLOGY; HISTOLOGY; MONOCLONAL ANTIBODIES; OPTICAL DESIGN;

CELL SHEET; CELLULAR CHANGES; CULTURE DISHES; CYTOKERATINS; EPITHELIAL CELLS; HUMAN PATIENTS; ORAL MUCOSA; PHENOTYPIC CHANGES; PHENOTYPIC MODULATION; PROGENITOR CELL; PROGENITOR CELLS; PROLIFERATING CELL NUCLEAR ANTIGEN; RAT MODELS; REGENERATIVE THERAPIES; SUBCUTANEOUS TISSUES; TEMPERATURE-RESPONSIVE; TISSUE ENGINEERING AUTOLOGOUS CELL;

CELLS;

CYCLINE; CYTOKERATIN 10; CYTOKERATIN 13; CYTOKERATIN 14; CYTOKERATIN 4; MONOCLONAL ANTIBODY; PROTEIN P63;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOTRANSPLANTATION; CELL CULTURE; CELL DEGENERATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; EPITHELIUM CELL; GENE EXPRESSION; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; MOUTH MUCOSA; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; RAT; SCANNING TRANSMISSION ELECTRON MICROSCOPY; STEM CELL; TEMPERATURE SENSITIVITY; TISSUE ENGINEERING; TISSUE REGENERATION; TISSUE TRANSPLANTATION;

ANIMALS; CELL CULTURE TECHNIQUES; CELL TRANSPLANTATION; EPITHELIAL CELLS; IMMUNOHISTOCHEMISTRY; KERATINS; MALE; MOUTH MUCOSA; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, INBRED LEW; STEM CELLS; SUBCUTANEOUS TISSUE; TEMPERATURE; TISSUE ENGINEERING; TRANSPLANTATION, AUTOLOGOUS;

EID: 50149099589     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31659     Document Type: Article

References (35)

1. Hefton JM, Madden MR, Finkelstein JL, Shires GT. Grafting of burn patients with allografts of cultured epidermal cells. Lancet 1983;2:428-430.
2. Gallico GG III, O'Connor NE, Compton CC, Kehinde O, Green H. Permanent coverage of large burn wounds with autologous cultured human epithelium. N Engl J Med 1984;311:448-451.
3. De Luca M, Albanese E, Bondanza S, Megna M, Ugozzoli L, Molina F, Cancedda R, Santi PL, Bormioli M, Stella M, Magliacani G. Multicentre experience in the treatment of burns with autologous and allogenic cultured epithelium, fresh or preserved in a frozen state. Burns 1989;15:303-309.
4. Gallico GG III, O'Connor NE, Compton CC, Remensnyder JP, Kehinde O, Green H. Cultured epithelial autografts for giant congenital nevi. Plast Reconstr Surg 1989;84:1-9.
5. Mavilio F, Pellegrini G, Ferrari S, Di Nunzio F, Di Iorio E, Recchia A, Maruggi G, Ferrari G, Provasi E, Bonini C, Capurro S, Conti A, Magnoni C, Giannetti A, De Luca M. Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells. Nat Med 2006;12:1397-1402.
6. Pellegrini G, Traverso CE, Franzi AT, Zingirian M, Cancedda R, De Luca M. Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium. Lancet 1997;349:990-993.
7. Tsai RJ, Li LM, Chen JK. Reconstruction of damaged corneas by transplantation of autologous limbal epithelial cells. N Engl J Med 2000;343:86-93.
8. Rama P, Bonini S, Lambiase A, Golisano O, Paterna P, De Luca M, Pellegrini G. Autologous fibrin-cultured limbal stem cells permanently restore the corneal surface of patients with total limbal stem cell deficiency. Transplantation 2001;72:1478-1485.
9. Nishida K, Yamato M, Hayashida Y, Watanabe K, Yamamoto K, Adachi E, Nagai S, Kikuchi A, Maeda N, Watanabe H, Okano T, Tano Y. Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium. N Engl J Med 2004;351:1187-1196.
10. Ohki T, Yamato M, Murakami D, Takagi R, Yang J, Namiki H, Okano T, Takasaki K. Treatment of oesophageal ulcerations using endoscopic transplantation of tissue-engineered autologous oral mucosal epithelial cell sheets in a canine model. Gut 2006;55:1704-1710.
11. Hayashida Y, Nishida K, Yamato M, Watanabe K, Maeda N, Watanabe H, Kikuchi A, Okano T, Tano Y. Ocular surface reconstruction using autologous rabbit oral mucosal epithelial sheets fabricated ex vivo on a temperature-responsive culture surface. Invest Ophthalmol Vis Sci 2005;46:1632-1639.
12. Barrandon Y, Li V, Green H. New techniques for the grafting of cultured human epidermal cells onto athymic animals. J Invest Dermatol 1988;91:315-318.
13. Hirose M, Kwon OH, Yamato M, Kikuchi A, Okano T. Creation of designed shape cell sheets that are noninvasively harvested and moved onto another surface. Biomacromolecules 2000;1:377-381.
14. Rheinwald JG, Green H. Serial cultivation of strains of human epidermal keratinocytes: The formation of keratinizing colonies from single cells. Cell 1975;6:331-343.
15. Murakami D, Yamato M, Nishida K, Ohki T, Takagi R, Yang J, Namiki FI, Okano T. Fabrication of transplantable human oral mucosal epithelial cell sheets using temperature-responsive culture inserts without feeder layer cells. J Artif Organs 2006;9:185-191.
16. Murakami D, Yamato M, Nishida K, Ohki T, Takagi R, Yang J, Namiki H, Okano T. The effect of micropores in the surface of temperature-responsive culture inserts on the fabrication of transplantable canine oral mucosal epithelial cell sheets. Biomaterials 2006;27:5518-5523.
17. Takeda A, Kadoya K, Shioya N, Uchinuma E, Tsunenaga M, Amano S, Nishiyama T, Burgeson RE. Pretreatment of human keratinocyte sheets with laminin 5 improves their grafting efficiency. J Invest Dermatol 1999;113:38-42.
18. Yamato M, Utsumi M, Kushida A, Konno C, Kikuchi A, Okano T. Thermo-responsive culture dishes allow the intact harvest of multilayered keratinocyte sheets without dispase by reducing temperature. Tissue Eng 2001;7:473-480.
19. Nishida K, Yamato M, Hayashida Y, Watanabe K, Maeda N, Watanabe H, Yamamoto K, Nagai S, Kikuchi A, Tano Y, Okano T. Functional bioengineered corneal epithelial sheet grafts from corneal stem cells expanded ex vivo on a temperature-responsive cell culture surface. Transplantation 2004;77:379-385.
20. Moll R, Franke WW, Schiller DL, Geiger B, Krepier R. The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells. Cell 1982;31:11-24.
21. Blanpain C, Fuchs E. Epidermal stem cells of the skin. Annu Rev Cell Dev Biol 2006;22:339-373.
22. Blanpain C, Horsley V, Fuchs E. Epithelial stem cells: Turning over new leaves. Cell 2007;128:445-458.
23. Green H, Kehinde O, Thomas J. Growth of cultured human epidermal cells into multiple epithelia suitable for grafting. Proc Natl Acad Sci USA 1979;76:5665-5668.
24. Barrandon Y, Green H. Three clonal types of keratinocyte with different capacities for multiplication. Proc Natl Acad Sci USA 1987;84:2302-2306.
25. Pellegrini G, Ranno R, Stracuzzi G, Bondanza S, Guerra L, Zambruno G, Micali G, De Luca M. The control of epidermal stem cells (holoclones) in the treatment of massive full-thickness burns with autologous keratinocytes cultured on fibrin. Transplantation 1999;68:868-879.
26. Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dotsch V, Andrews NC, Caput D, McKeon F. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell 1998;2:305-316.
27. Pellegrini G, Dellambra E, Golisano O, Martinelli E, Fantozzi I, Bondanza S, Ponzin D, McKeon F, De Luca M. p63 identifies keratinocyte stem cells. Proc Natl Acad Sci USA 2001;98:3156-3161.
28. Di Iorio E, Barbaro V, Ruzza A, Ponzin D, Pellegrini G, De Luca M. Isoforms of ΔNp63 and the migration of ocular limbal cells in human corneal regeneration. Proc Natl Acad Sci USA 2005;102:9523-9528.
29. Di Iorio E, Barbaro V, Ferrari S, Ortolani C, De Luca M, Pellegrini G. Q-FIHC: Quantification of fluorescence immunohistochemistry to analyse p63 isoforms and cell cycle phases in human limbal stem cells. Microsc Res Tech 2006;69:983-991.
30. Yang A, Schweitzer R, Sun D, Kaghad M, Walker N, Bronson RT, Tabin C, Sharpe A, Caput D, Crum C, McKeon F. p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 1999;398:714-718.
31. Takasaki Y, Deng JS, Tan EM. A nuclear antigen associated with cell proliferation and blast transformation. J Exp Med 1981;154:1899-1909.
32. Counter CM, Press W, Compton CC. Telomere shortening in cultured autografts of patients with burns. Lancet 2003;361:1345-1346.
33. Ricordi C, Lacy PE, Callery MP, Park PW, Flye MW. Trophic factors from pancreatic islets in combined hepatocyte-islet allografts enhance hepatocellular survival. Surgery 1989;105(2, Part 1):218-223.
34. Ohashi K, Waugh JM, Dake MD, Yokoyama T, Kuge H, Nakajima Y, Yamanouchi M, Naka H, Yoshioka A, Kay MA. Liver tissue engineering at extrahepatic sites in mice as a potential new therapy for genetic liver diseases. Hepatology 2005;41:132-140.
35. Yokoyama T, Ohashi K, Kuge H, Kanehiro H, Iwata H, Yamato M, Nakajima Y. In vivo engineering of metabolically active hepatic tissues in a neovascularized subcutaneous cavity. Am J Transplant 2006;6:50-59.