메뉴 건너뛰기




Volumn 31, Issue 16, 2008, Pages 2442-2454

Determination of flunitrazepam in human plasma and urine by HPLC with mass spectrometry detection

Author keywords

Flunitrazepam; Liquid chromatography; Mass spectrometry; Plasma; Urine; Validation

Indexed keywords

ATMOSPHERIC PRESSURE; ATMOSPHERICS; CHROMATOGRAPHIC ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; ION SOURCES; IONIZATION OF LIQUIDS; IONS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; PLASMA (HUMAN); PLASMAS; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS;

EID: 50049105830     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826070802319636     Document Type: Article
Times cited : (8)

References (20)
  • 1
    • 33646058023 scopus 로고    scopus 로고
    • Abuse of prescription drugs and the risk of addiction
    • Compton, E.M.; Volkow, N.D. Abuse of prescription drugs and the risk of addiction. Drug Alcohol Depend. 2006, 83S, S4-S7.
    • (2006) Drug Alcohol Depend , vol.83 S
    • Compton, E.M.1    Volkow, N.D.2
  • 2
    • 27644509178 scopus 로고    scopus 로고
    • Correlates of nonmedical use of prescription benzodiazepine anxiolytics: Results from a national survey of US
    • McCabe, S.E. Correlates of nonmedical use of prescription benzodiazepine anxiolytics: results from a national survey of US. Drug Alcohol Depend. 2005, 79, 53-62.
    • (2005) Drug Alcohol Depend , vol.79 , pp. 53-62
    • McCabe, S.E.1
  • 3
    • 0035500972 scopus 로고    scopus 로고
    • Flunitrazepam: An evaluation of use, abuse and toxicity
    • Druid, H.; Holmgren, P.; Ahlner, J. Flunitrazepam: an evaluation of use, abuse and toxicity. Foren. Sci. Int. 2001, 122, 136-141.
    • (2001) Foren. Sci. Int , vol.122 , pp. 136-141
    • Druid, H.1    Holmgren, P.2    Ahlner, J.3
  • 4
    • 31544465470 scopus 로고    scopus 로고
    • A case of drug-facilitated sexual assault by the use of flunitrazepam
    • Ohshima, T. A case of drug-facilitated sexual assault by the use of flunitrazepam. J. Clin. Foren. Med. 2006, 13, 44-45.
    • (2006) J. Clin. Foren. Med , vol.13 , pp. 44-45
    • Ohshima, T.1
  • 5
    • 32644448772 scopus 로고    scopus 로고
    • Extraction and analysis of flunitrazepam/ 7-aminoflunitrazepam in blood and urine by LC-PDA and GC-MS using butyl SPE columns
    • Hackett, J.; Elian, A.A. Extraction and analysis of flunitrazepam/ 7-aminoflunitrazepam in blood and urine by LC-PDA and GC-MS using butyl SPE columns. Foren. Sci. Int. 2006, 157, 156-162.
    • (2006) Foren. Sci. Int , vol.157 , pp. 156-162
    • Hackett, J.1    Elian, A.A.2
  • 6
    • 0034663838 scopus 로고    scopus 로고
    • Simultaneous determination of benzodiazepines in whole blood or serum by HPLC/DAD with a semi-micro column
    • El Mahjoub, A.; Staub, C. Simultaneous determination of benzodiazepines in whole blood or serum by HPLC/DAD with a semi-micro column. J. Pharm. Biomed. Anal. 2000, 23, 447-458.
    • (2000) J. Pharm. Biomed. Anal , vol.23 , pp. 447-458
    • El Mahjoub, A.1    Staub, C.2
  • 7
    • 0034625476 scopus 로고    scopus 로고
    • High-performance liquid chromatographic method for the determination of benzodiazepines in plasma or serum using the column-switching technique
    • El Mahjoub, A.; Staub, C. High-performance liquid chromatographic method for the determination of benzodiazepines in plasma or serum using the column-switching technique. J. Chromatogr. B Biomed. Sci. Appl. 2000, 742 (2), 381-390.
    • (2000) J. Chromatogr. B Biomed. Sci. Appl , vol.742 , Issue.2 , pp. 381-390
    • El Mahjoub, A.1    Staub, C.2
  • 8
    • 0030601728 scopus 로고    scopus 로고
    • Simultaneous high-performance liquid chromatographic analysis of flunitrazepam and four metabolites in serum
    • Berthault, F.; Kintz, P.; Mangin, P. Simultaneous high-performance liquid chromatographic analysis of flunitrazepam and four metabolites in serum. J. Chromatogr. B Biomed. Appl. 1996, 685 (2), 383-387.
    • (1996) J. Chromatogr. B Biomed. Appl , vol.685 , Issue.2 , pp. 383-387
    • Berthault, F.1    Kintz, P.2    Mangin, P.3
  • 10
    • 5344229411 scopus 로고    scopus 로고
    • Quantitative analysis of 33 benzodiazepines, metabolites and benzodiazepine-like substances in whole blood by liquid chromatography-(tandem) mass spectrometry
    • Smink, B.E.; Brandsma, J.E.; Dijkhuizen, A.; Lusthof, K.J.; de Gier, J.J.; Egberts, A.C.G.; Uges, D.R.A. Quantitative analysis of 33 benzodiazepines, metabolites and benzodiazepine-like substances in whole blood by liquid chromatography-(tandem) mass spectrometry. J. Chromatogr. B 2004, 811, 13-20.
    • (2004) J. Chromatogr. B , vol.811 , pp. 13-20
    • Smink, B.E.1    Brandsma, J.E.2    Dijkhuizen, A.3    Lusthof, K.J.4    de Gier, J.J.5    Egberts, A.C.G.6    Uges, D.R.A.7
  • 11
    • 33644747271 scopus 로고    scopus 로고
    • A fast LC-APCI/MS method for analysing benzodiazepines in whole blood using monolithic support
    • Bugey, A.; Rudaz, S.; Staub, C. A fast LC-APCI/MS method for analysing benzodiazepines in whole blood using monolithic support. J. Chromatogr. B 2006, 832, 249-255.
    • (2006) J. Chromatogr. B , vol.832 , pp. 249-255
    • Bugey, A.1    Rudaz, S.2    Staub, C.3
  • 12
    • 24344483851 scopus 로고    scopus 로고
    • Liquid chromatography-electrospray ionization mass-spectrometry for the determination of nine selected benzodiazepines in human plasma and oral fluid
    • Quintela, O.; Cruz, A.; de Castro, A.; Concheiro, M.; Lopez-Rivadulla, M. Liquid chromatography-electrospray ionization mass-spectrometry for the determination of nine selected benzodiazepines in human plasma and oral fluid. J. Chromatogr. B 2005, 825, 63-71.
    • (2005) J. Chromatogr. B , vol.825 , pp. 63-71
    • Quintela, O.1    Cruz, A.2    de Castro, A.3    Concheiro, M.4    Lopez-Rivadulla, M.5
  • 13
    • 34248358661 scopus 로고    scopus 로고
    • Determination of flunitrazepam and 7-aminoflunitrazepam in human urine by on-line solid phase extraction liquid chromatography-electrospray-tandem masss-pectrometry
    • Fuh, M.-R.; Lin, S.-W.; Chen, L.-L.; Lin, T.-Y. Determination of flunitrazepam and 7-aminoflunitrazepam in human urine by on-line solid phase extraction liquid chromatography-electrospray-tandem masss-pectrometry. Talanta 2007, 72, 1329-1335.
    • (2007) Talanta , vol.72 , pp. 1329-1335
    • Fuh, M.-R.1    Lin, S.-W.2    Chen, L.-L.3    Lin, T.-Y.4
  • 14
    • 34249706845 scopus 로고    scopus 로고
    • Rapid determination of omeprazole in human plasma by protein precipitation and liquid chromatography-tandem mass spectrometry
    • Macek, J.; Klíma, J.; Ptáček, P. Rapid determination of omeprazole in human plasma by protein precipitation and liquid chromatography-tandem mass spectrometry. J. Chromatogr. B 2007, 852, 282-287.
    • (2007) J. Chromatogr. B , vol.852 , pp. 282-287
    • Macek, J.1    Klíma, J.2    Ptáček, P.3
  • 15
    • 2942564444 scopus 로고    scopus 로고
    • Development and validation of a gas chromatography-mass spectrometry method for the simultaneous determination of buprenorphine, flunitrazepam and their metabolites in rat plasma: Application to the pharmacokinetic study
    • Pirnay, S.; Bouchonnet, S.; Herve, F.; Libong, D.; Milan, N.; d'Athis, P.; Baud, F.; Ricordel, I. Development and validation of a gas chromatography-mass spectrometry method for the simultaneous determination of buprenorphine, flunitrazepam and their metabolites in rat plasma: application to the pharmacokinetic study. J. Chromatogr. B 2004, 807, 335-342.
    • (2004) J. Chromatogr. B , vol.807 , pp. 335-342
    • Pirnay, S.1    Bouchonnet, S.2    Herve, F.3    Libong, D.4    Milan, N.5    d'Athis, P.6    Baud, F.7    Ricordel, I.8
  • 16
  • 17
    • 50049127515 scopus 로고    scopus 로고
    • Guidance for Industry. Bioavailability and Bioequivalence Studies for Orally Administered Drug Products-General Considerations, Rockville
    • U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research
    • U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research. Guidance for Industry. Bioavailability and Bioequivalence Studies for Orally Administered Drug Products-General Considerations, Rockville, USA, March 2003, http://www.fda.gov/cder/guidance/index.htm.
    • (2003) USA, March
  • 18
    • 2542465496 scopus 로고    scopus 로고
    • U.S. Department of Health and Human Services, Center for Drug Evaluation and Research. Guidance for Industry-Bioanalytical Method Validation, May
    • U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research. Guidance for Industry-Bioanalytical Method Validation, May 2001.
    • (2001) Food and Drug Administration
  • 19
    • 8444250979 scopus 로고    scopus 로고
    • Matrix effect in LC-ESI-MS and LC-APCI-MS with off-line and on-line extraction procedures
    • Souverain, S.; Rudaz, S.; Veuthey, J.-L. Matrix effect in LC-ESI-MS and LC-APCI-MS with off-line and on-line extraction procedures. J. Chromatogr. A 2004, 1058, 61-66.
    • (2004) J. Chromatogr. A , vol.1058 , pp. 61-66
    • Souverain, S.1    Rudaz, S.2    Veuthey, J.-L.3
  • 20
    • 8444232111 scopus 로고    scopus 로고
    • Evaluation of three calibration methods to compensate matrix effects in environmental analysis with LC-ESI-MS
    • Stüber, M.; Reemtsma, T. Evaluation of three calibration methods to compensate matrix effects in environmental analysis with LC-ESI-MS. Anal. Bioanal. Chem. 2004, 378, 910-916.
    • (2004) Anal. Bioanal. Chem , vol.378 , pp. 910-916
    • Stüber, M.1    Reemtsma, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.