Synthesis and calpain inhibitory activity of peptidomimetic compounds with constrained amino acids at the P2 position

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 17, 2008, Pages 4806-4808

  Donkor, Isaac O ^a   Korukonda, Rajani ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Calpain; Cathepsin; Constrained amino acids; Cysteine proteases; Inhibitors; Peptidomimetics

Indexed keywords

ALPHA AMINOCYCLOPENTANE CARBOXYLIC ACID; ALPHA,ALPHA' DIETHYLGLYCINE; AMINO ACID; CALPAIN 1; CALPASTATIN; CATHEPSIN B; CYSTEINE PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG POTENCY; DRUG SYNTHESIS;

AMINO ACIDS; ANIMALS; BIOMIMETIC MATERIALS; CALPAIN; CATHEPSIN B; CYSTEINE PROTEINASE INHIBITORS; DRUG DESIGN; HUMANS; PEPTIDES; SWINE;

EID: 49949117649     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.07.094     Document Type: Article

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