Sex-specific differences in ischemic heart failure: Role of estrogen

Gender Medicine

Volumn 5, Issue 3, 2008, Pages 239-243

  Bauer, Michael ^a   Podesser, Bruno K ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CANDESARTAN; ESTROGEN; GESTAGEN; SEX HORMONE; WARFARIN;

AGE; ARTICLE; CAUSE OF DEATH; CIGARETTE SMOKING; CLINICAL TRIAL; CONGESTIVE HEART FAILURE; ECHOCARDIOGRAPHY; FEMALE; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART PROTECTION; HORMONE SUBSTITUTION; HUMAN; HYPERTENSION; INCIDENCE; MALE; MEDICAL RESEARCH; MORBIDITY; MORTALITY; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; SEX DIFFERENCE; SURVIVAL RATE; TREATMENT OUTCOME;

ESTROGENS; FEMALE; HEART FAILURE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; RISK; SEX FACTORS; SURVIVAL ANALYSIS;

EID: 49849095627     PISSN: 15508579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.genm.2008.08.003     Document Type: Article

References (22)

1. World Health Organization. World Health Statistics 2007. http://www.who.int/whosis/whostat/2007/en/index.html. Accessed July 29, 2008.
2. Rosamond W., Flegal K., Friday G., et al., For the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics-2007 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee [published correction appears in Circulation. 2007;115:e172]. Circulation 115 (2007) e69-e171
3. Christian A.H., Rosamond W., White A.R., and Mosca L. Nine-year trends and racial and ethnic disparities in women's awareness of heart disease and stroke. J Womens Health 16 (2007) 68-81
4. Bello N., and Mosca L. Epidemiology of coronary heart disease in women. Prog Cardiovasc Dis 46 (2004) 287-295
5. Gustafsson F., Torp-Pedersen C., Burchardt H., et al., For the DIAMOND Study Group. Female sex is associated with a better long-term survival in patients hospitalized with congestive heart failure. Eur Heart J 25 (2004) 129-135
6. Hulley S., Grady D., Bush T., et al., For the Heart and Estrogen/progestin Replacement Study (HERS) Research Group. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. JAMA 280 (1998) 605-613
7. Adams Jr. K.F., Dunlap S.H., Sueta C.A., et al. Relation between gender, etiology and survival in patients with symptomatic heart failure. J Am Coll Cardiol 28 (1996) 1781-1788
8. Ghali J.K., Krause-Steinrauf H.J., Adams K.F., et al. Gender differences in advanced heart failure: Insights from the BEST study. J Am Coll Cardiol 42 (2003) 2128-2134
9. O'Meara E., Clayton T., McEntegart M.B., et al., For the CHARM Investigators. Sex differences in clinical characteristics and prognosis in a broad spectrum of patients with heart failure: Results of the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM) program. Circulation 115 (2007) 3111-3120
10. Vaccarino V., Parsons L., Every N.R., et al., For the National Registry of Myocardial Infarction 2 Participants. Sex-based differences in early mortality after myocardial infarction. N Engl J Med 341 (1999) 217-225
11. Leinwand L.A. Sex is a potent modifier of the cardiovascular system. J Clin Invest 112 (2003) 302-307
12. Podesser B.K., Jain M., Ngoy S., et al. Unveiling gender differences in demand ischemia: A study in a M. Bauer and B.K. Podesser rat model of genetic hypertension. Eur J Cardiothorac Surg 31 (2007) 298-304
13. Litwin S.E., Katz S.E., Litwin C.M., et al. Gender differences in postinfarction left ventricular remodeling. Cardiology 91 (1999) 173-183
14. Hügel S., Reincke M., Strömer H., et al. Evidence against a role of physiological concentrations of estrogen in post-myocardial infarction remodeling. J Am Coll Cardiol 34 (1999) 1427-1434
15. van Eickels M., Patten R.D., Aronovitz M.J., et al. 17-Beta-estradiol increases cardiac remodeling and mortality in mice with myocardial infarction [published correction appears in J Am Coll Cardiol. 2003;42:following 183]. J Am Coll Cardiol 41 (2003) 2084-2092
16. Babiker F.A., De Windt L.J., van Eickels M., et al. 17-Beta-estradiol antagonizes cardiomyocyte hypertrophy by autocrine/paracrine stimulation of a guanylyl cyclase A receptor-cyclic guanosine monophosphate-dependent protein kinase pathway. Circulation 109 (2004) 269-276
17. Nekooeian A.A., and Pang C.C. Estrogen restores role of basal nitric oxide in control of vascular tone in rats with chronic heart failure. Am J Physiol 274 (1998) H2094-H2099
18. Cavasin M.A., Tao Z., Menon S., and Yang X.P. Gender differences in cardiac function during early remodeling after acute myocardial infarction in mice. Life Sci 75 (2004) 2181-2192
19. Pelzer T., Loza P.A., Hu K., et al. Increased mortality and aggravation of heart failure in estrogen receptor-beta knockout mice after myocardial infarction. Circulation 111 (2005) 1492-1498
20. Grady D., Herrington D., Bittner V., et al., For the HERS Research Group. Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II) [published correction appears in JAMA. 2002;288:1064]. JAMA 288 (2002) 49-57
21. Alexander K.P., Newby L.K., Hellkamp A.S., et al. Initiation of hormone replacement therapy after acute myocardial infarction is associated with more cardiac events during follow-up. J Am Coll Cardiol 38 (2001) 1-7
22. Manson J.E., Hsia J., Johnson K.C., et al., For the Women's Health Initiative Investigators. Estrogen plus progestin and the risk of coronary heart disease. N Engl J Med 349 (2003) 523-534